المؤلفون: Strathearn, Lauren E., Spender, Lindsay, Schoenherr, Christina, Mason, Susan, Edwards, Ruaridh, Blyth, Karen, Inman, Gareth J

المصدر: Strathearn , L E , Spender , L , Schoenherr , C , Mason , S , Edwards , R , Blyth , K & Inman , G J 2024 , ' C1orf106 (INAVA) Is a SMAD3-Dependent TGF-β Target Gene That Promotes Clonogenicity and Correlates with Poor Prognosis in Breast Cancer ' , Cells , vol. 13 , no. 18 , 1530 . https://doi.org/10.3390/cells13181530

مصطلحات موضوعية: C1orf106, INAVA, TGF-β, breast carcinoma, /dk/atira/pure/subjectarea/asjc/1300/1300, name=General Biochemistry,Genetics and Molecular Biology

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/100160b3-2e77-4967-a9fb-07d036de3dc6
https://doi.org/10.3390/cells13181530
https://discovery.dundee.ac.uk/ws/files/136735316/cells-13-01530.pdf
http://www.scopus.com/inward/record.url?scp=85205109013&partnerID=8YFLogxK

المؤلفون: Strathearn, Lauren S., Spender, Lindsay C., Schoenherr, Christina, Mason, Susan, Edwards, Ruaridh, Blyth, Karen, Inman, Gareth

وصف الملف: text

Relation: https://eprints.gla.ac.uk/334456/1/334456.pdf; Strathearn, L. S., Spender, L. C., Schoenherr, C. , Mason, S. , Edwards, R., Blyth, K. and Inman, G. (2024) C1orf106 (INAVA) is a SMAD3-dependent TGF-β target gene that promotes clonogenicity and correlates with poor prognosis in breast cancer. Cells , 13(18), 1530. (doi:10.3390/cells13181530 )

الاتاحة: https://eprints.gla.ac.uk/334456/
https://eprints.gla.ac.uk/334456/1/334456.pdf

المؤلفون: Baxter, Mark, Spender, Lindsay, Cairns, David, Walsh, S., Oparka, R., Porter, R. J., Bray, S., Skinner, G., King, S., Turbitt, J., Collinson, D., Miedzybrodzka, Z. H., Jellema, G., Logan, G., Kennedy, Richard, Turkington, Richard, McLean, Mairi H., Swinson, D., Grabsch, H. I., lord, simon, Seymour, Matthew, Hall, P. S., Petty, R. D.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/330845/1/330845.pdf; Baxter, M. et al. (2024) An investigation of the clinical impact and therapeutic relevance of a DNA damage immune response (DDIR) signature in patients with advanced gastroesophageal adenocarcinoma. ESMO Open , 9(5), 103450. (doi:10.1016/j.esmoop.2024.103450 ) (PMID:38744099) (PMCID:PMC11108838)

الاتاحة: https://eprints.gla.ac.uk/330845/
https://eprints.gla.ac.uk/330845/1/330845.pdf

المؤلفون: Baxter, Mark A., Spender, Lindsay C., Walsh, Shaun, Bray, Susan, Skinner, Gemma, King, Sharon, Hall, Peter S., Seymour, Matthew J., Petty, Russell D.

المصدر: Baxter , M A , Spender , L C , Walsh , S , Bray , S , Skinner , G , King , S , Hall , P S , Seymour , M J , Petty , R D & GO2 Trial Investigators 2023 , ' Female sex but not oestrogen receptor expression predicts survival in advanced gastroesophageal adenocarcinoma—a post-hoc analysis of the go2 trial ' , Cancers , vol. 15 , no. 9 , 2591 . https://doi.org/10.3390/cancers15092591

مصطلحات موضوعية: gastroesophageal cancer, oestrogen receptor, older adults, prognosis, biomarker, /dk/atira/pure/subjectarea/asjc/2700/2730, name=Oncology, /dk/atira/pure/subjectarea/asjc/1300/1306, name=Cancer Research

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/a278b888-8b6a-4f23-b0ab-49eaa9b44dac
https://doi.org/10.3390/cancers15092591
https://discovery.dundee.ac.uk/ws/files/101657253/cancers_15_02591.pdf
http://www.scopus.com/inward/record.url?scp=85159632300&partnerID=8YFLogxK

المؤلفون: Meemanage, Madusha, Spender, Lindsay C., Collinson, Diane, Iannetta, Joanna, Challapalli, Pranavi, Turbitt, Julie, Clark, Caroline, Baxter, Mark, Murray, Graeme, Walsh, Shaun, Miedzybrodzka, Zofia, Petty, Russell D.

المصدر: Meemanage , M , Spender , L C , Collinson , D , Iannetta , J , Challapalli , P , Turbitt , J , Clark , C , Baxter , M , Murray , G , Walsh , S , Miedzybrodzka , Z & Petty , R D 2021 , ' Interactions between anti-EGFR therapies and cytotoxic chemotherapy in oesophageal squamous cell carcinoma: why clinical trials might have failed and how they could succeed ' , Cancer Chemotherapy and Pharmacology , vol. 87 , pp. 361-377 . https://doi.org/10.1007/s00280-020-04187-w

مصطلحات موضوعية: Gastroesophageal cancer, Gefitinib, EGFR, Docetaxel, Platinum, ESCC, Chemotherapy combinations, /dk/atira/pure/subjectarea/asjc/2700/2736, name=Pharmacology (medical), /dk/atira/pure/subjectarea/asjc/2700/2730, name=Oncology, /dk/atira/pure/subjectarea/asjc/1300/1306, name=Cancer Research, /dk/atira/pure/subjectarea/asjc/3000/3005, name=Toxicology, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/67a8ea50-dac1-48ca-a0d2-f38a05715189

الاتاحة: https://discovery.dundee.ac.uk/en/publications/67a8ea50-dac1-48ca-a0d2-f38a05715189
https://doi.org/10.1007/s00280-020-04187-w
https://discovery.dundee.ac.uk/ws/files/54388914/Meemanage2020_Article_InteractionsBetweenAnti_EGFRTh.pdf

المؤلفون: Baxter, Mark, Spender, Lindsay, Petty, Russell

المصدر: Baxter , M , Spender , L & Petty , R 2020 , ' Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma ' , British Journal of Cancer , vol. 123 , no. 11 , pp. 1585-1587 . https://doi.org/10.1038/s41416-020-01057-3

مصطلحات موضوعية: Oesophageal cancer, /dk/atira/pure/subjectarea/asjc/2700/2730, name=Oncology, /dk/atira/pure/subjectarea/asjc/1300/1306, name=Cancer Research

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/e467a26f-fbf6-43e2-8ecb-2e8b08a35c20

الاتاحة: https://discovery.dundee.ac.uk/en/publications/e467a26f-fbf6-43e2-8ecb-2e8b08a35c20
https://doi.org/10.1038/s41416-020-01057-3
https://discovery.dundee.ac.uk/ws/files/52689765/Final_Published_Version.pdf
http://www.scopus.com/inward/record.url?scp=85091161562&partnerID=8YFLogxK

المؤلفون: Spender, Lindsay C., Ferguson, G. John, Hughes, Gareth D., Davies, Barry R., Goldberg, Frederick W., Herrera, Blanca, Taylor, Richard G., Strathearn, Lauren, Sansom, Owen J., Barry, Simon T., Inman, Gareth

المصدر: Spender , L C , Ferguson , G J , Hughes , G D , Davies , B R , Goldberg , F W , Herrera , B , Taylor , R G , Strathearn , L , Sansom , O J , Barry , S T & Inman , G 2019 , ' Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor β Superfamily Type 1 Receptors. ' , Molecular Pharmacology , vol. 95 , no. 2 , pp. 222-234 . https://doi.org/10.1124/mol.118.112946

مصطلحات موضوعية: Activin Receptors, Type I/metabolism, Animals, Bone Morphogenetic Proteins/metabolism, Cell Line, Cell Proliferation/drug effects, DNA-Binding Proteins, Mice, NIH 3T3 Cells, Neoplasm Metastasis/pathology, Phosphorylation/drug effects, Protein Kinase Inhibitors/pharmacology, Receptor, Transforming Growth Factor-beta Type I/metabolism, Signal Transduction/drug effects, Smad2 Protein/metabolism, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/d762b2cc-a82d-46da-bc0e-5e2bbfaf029f
https://doi.org/10.1124/mol.118.112946
https://discovery.dundee.ac.uk/ws/files/29210625/Author_Accepted_Manuscript.pdf
http://www.scopus.com/inward/record.url?scp=85059879858&partnerID=8YFLogxK

المؤلفون: Inman, Gareth J., Wang, Jun, Nagano, Ai, Alexandrov, Ludmil B., Purdie, Karin J., Taylor, Richard G., Sherwood, Victoria, Thomson, Jason, Hogan, Sarah, Spender, Lindsay C., South, Andrew P., Stratton, Michael, Chelala, Claude, Harwood, Catherine A., Proby, Charlotte M., Leigh, Irene M.

المصدر: Inman , G J , Wang , J , Nagano , A , Alexandrov , L B , Purdie , K J , Taylor , R G , Sherwood , V , Thomson , J , Hogan , S , Spender , L C , South , A P , Stratton , M , Chelala , C , Harwood , C A , Proby , C M & Leigh , I M 2018 , ' The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature ' , Nature Communications , vol. 9 , no. ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/1600/1600, name=General Chemistry, /dk/atira/pure/subjectarea/asjc/1300/1300, name=General Biochemistry,Genetics and Molecular Biology, /dk/atira/pure/subjectarea/asjc/3100/3100, name=General Physics and Astronomy

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/9839180b-71d1-43c5-b6f2-e438402da062
https://doi.org/10.1038/s41467-018-06027-1
https://discovery.dundee.ac.uk/ws/files/28466773/s41467_018_06027_1.pdf

المؤلفون: Rose, Aidan M., Spender, Lindsay C., Stephen, Christopher, Mitchell, Alastair, Rickaby, William, Bray, Susan, Evans, Alan T., Dayal, Jasbani, Purdie, Karin J., Harwood, Catherine A., Proby, Charlotte M., Leigh, Irene M., Coates, Philip J ., Inman, Gareth J.

المصدر: Rose , A M , Spender , L C , Stephen , C , Mitchell , A , Rickaby , W , Bray , S , Evans , A T , Dayal , J , Purdie , K J , Harwood , C A , Proby , C M , Leigh , I M , Coates , P J & Inman , G J 2018 , ' Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma ' , Oncotarget , vol. 9 , no. 18 , pp. 14552-14566 . https://doi.org/10.18632/oncotarget.24545

مصطلحات موضوعية: Carcinoma, FFPE, IHC, SMAD, TGF-β, /dk/atira/pure/subjectarea/asjc/2700/2730, name=Oncology

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/721b0998-a06a-483f-82fb-00203c7d4578

الاتاحة: https://discovery.dundee.ac.uk/en/publications/721b0998-a06a-483f-82fb-00203c7d4578
https://doi.org/10.18632/oncotarget.24545
https://discovery.dundee.ac.uk/ws/files/20370191/24545_343565_7_PB.pdf
http://www.scopus.com/inward/record.url?scp=85042923342&partnerID=8YFLogxK

المؤلفون: Cammareri, Patrizia, Rose, Aidan M., Vincent, David F., Wang, Jun, Nagano, Ai, Libertini, Silvana, Ridgway, Rachel A., Athineos, Dimitris, Coates, Philip J., McHugh, Angela, Pourreyron, Celine, Dayal, Jasbani H S, Larsson, Jonas, Weidlich, Simone, Spender, Lindsay C., Sapkota, Gopal P., Purdie, Karin J., Proby, Charlotte M., Harwood, Catherine A., Leigh, Irene M., Clevers, Hans, Barker, Nick, Karlsson, Stefan, Pritchard, Catrin, Marais, Richard, Chelala, Claude, South, Andrew P., Sansom, Owen J., Inman, Gareth J.

المصدر: Nature Communications StemTherapy: National Initiative on Stem Cells for Regenerative Therapy BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation. 7

مصطلحات موضوعية: Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Cell- och molekylärbiologi, Medical and Health Sciences, Basic Medicine, Cell and Molecular Biology

URL الوصول: https://lup.lub.lu.se/record/566613de-909e-4bcc-a755-0731e8ca92c9
http://dx.doi.org/10.1038/ncomms12493

المؤلفون: Spender, Lindsay C., Inman, Gareth J.

المصدر: Spender , L C & Inman , G J 2017 , ' Targeting BRAF-mutant tumours with TGFBR1 inhibitors ' , Aging , vol. 9 , no. 1 , pp. 5-6 . https://doi.org/10.18632/aging.101169

مصطلحات موضوعية: TGFβ, BRAF, melanoma, therapy

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/e2e3c7db-2788-40c9-abca-a3393087a9ec

الاتاحة: https://discovery.dundee.ac.uk/en/publications/e2e3c7db-2788-40c9-abca-a3393087a9ec
https://doi.org/10.18632/aging.101169
https://discovery.dundee.ac.uk/ws/files/11856692/5g7xPefurPpwBqr3p.pdf

المؤلفون: Spender, Lindsay C., Ferguson, G. John, Liu, Sijia, Cui, Chao, Girotti, Maria Romina, Sibbet, Gary, Higgs, Ellen B., Shuttleworth, Morven K., Hamilton, Tom, Lorigan, Paul, Weller, Michael, Vincent, David F., Sansom, Owen J., Frame, Margaret, Ten Dijke, Peter, Marais, Richard, Inman, Gareth J.

المصدر: Spender , L C , Ferguson , G J , Liu , S , Cui , C , Girotti , M R , Sibbet , G , Higgs , E B , Shuttleworth , M K , Hamilton , T , Lorigan , P , Weller , M , Vincent , D F , Sansom , O J , Frame , M , Ten Dijke , P , Marais , R & Inman , G J 2016 , ' Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells ' , Oncotarget , ....

مصطلحات موضوعية: melanoma, BRAF, verurafenib, PLX-4720, TFG-beta

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/2a08233e-bd3d-498d-9501-9601d740760e

الاتاحة: https://discovery.dundee.ac.uk/en/publications/2a08233e-bd3d-498d-9501-9601d740760e
https://doi.org/10.18632/oncotarget.13226
https://discovery.dundee.ac.uk/ws/files/11938540/13226_197669_1_PB.pdf

المؤلفون: Spender, Lindsay C., Inman, Gareth J.

وصف الملف: text

Relation: http://eprints.gla.ac.uk/178931/1/178931.pdf; Spender, L. C. and Inman, G. J. (2014) Developments in Burkitt's lymphoma: novel cooperations in oncogenic MYC signaling. Cancer Management and Research , 6, pp. 27-38. (doi:10.2147/CMAR.S37745 ) (PMID:24426788) (PMCID:PMC3890408)

الاتاحة: http://eprints.gla.ac.uk/178931/
http://eprints.gla.ac.uk/178931/1/178931.pdf

المؤلفون: Inman, Gareth, Spender, Lindsay

المصدر: Cancer Management and Research ; page 27 ; ISSN 1179-1322

الاتاحة: http://dx.doi.org/10.2147/cmar.s37745
https://www.dovepress.com/getfile.php?fileID=18640

المؤلفون: Spender, Lindsay C., Carter, Matthew J., O'Brien, Darren I., Clark, Louise J., Yu, Jian, Michalak, Ewa M., Happo, Lina, Cragg, Mark S., Inman, Gareth J.

المصدر: Journal of Biological Chemistry ; volume 288, issue 7, page 5198-5209 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.m112.410274
https://api.elsevier.com/content/article/PII:S0021925820463239?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820463239?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M112.410274

المؤلفون: Spender, Lindsay C., Inman, Gareth J.

وصف الملف: text

Relation: http://eprints.gla.ac.uk/178975/1/178975.pdf; Spender, L. C. and Inman, G. J. (2011) Inhibition of germinal centre apoptotic programmes by Epstein-Barr Virus. Advances in Hematology , 2011, 829525. (doi:10.1155/2011/829525 ) (PMID:22110506) (PMCID:PMC3202104)

الاتاحة: http://eprints.gla.ac.uk/178975/
http://eprints.gla.ac.uk/178975/1/178975.pdf

المؤلفون: Hannigan, Adele, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I., Shah, Reshma, Syed, Nelofer, Spender, Lindsay C., Herrera, Blanca, Thurlow, Johanna K., Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E., Buffa, Francesca M., Mann, Jelena, Chu, David C. K., West, Catharine M. L., Patridge, Max, Oien, Karin A., Cooper, Jonathan A., Frame, Margaret C., Harris, Adrian L., Hiller, Louise, Nicholson, Linda J., Gasco, Milena, Crook, Tim, Inman, Gareth J.

المصدر: Hannigan , A , Smith , P , Kalna , G , Lo Nigro , C , Orange , C , O'Brien , D I , Shah , R , Syed , N , Spender , L C , Herrera , B , Thurlow , J K , Lattanzio , L , Monteverde , M , Maurer , M E , Buffa , F M , Mann , J , Chu , D C K , West , C M L , Patridge , M , Oien , K A , Cooper , J A , Frame , M ....

مصطلحات موضوعية: GROWTH-FACTOR-BETA, CHEMICALLY TRANSFORMED-CELLS, BREAST-CANCER, ADAPTER PROTEIN, DAB2, GENE, METASTASIS, EXPRESSION, RECEPTORS, PATHWAY

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/c8ccb32a-d025-4a84-ab14-346eb255383b
https://doi.org/10.1172/JCI36125
https://discovery.dundee.ac.uk/ws/files/733359/Hannigan_2010.v2_2_.pdf
http://www.scopus.com/inward/record.url?scp=77955295090&partnerID=8YFLogxK

المؤلفون: Spender, Lindsay C., Inman, Gareth J.

المصدر: Journal of Biological Chemistry ; volume 284, issue 3, page 1435-1442 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.m808080200
https://api.elsevier.com/content/article/PII:S0021925819821592?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925819821592?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M808080200

المؤلفون: Birch, Joanna L., Coull, Barry J., Spender, Lindsay C., Watt, Courtney, Willison, Alice, Syed, Nelofer, Chalmers, Anthony J., Hossain-Ibrahim, M. Kismet, Inman, Gareth J.

Relation: Birch, Joanna L. and Coull, Barry J. and Spender, Lindsay C. and Watt, Courtney and Willison, Alice and Syed, Nelofer and Chalmers, Anthony J. and Hossain-Ibrahim, M. Kismet and Inman, Gareth J. (2020) Multifaceted transforming growth factor-beta (TGFβ) signalling in glioblastoma. Cellular Signalling, 72. p. 109638. ISSN 0898-6568

الاتاحة: https://eprints.lancs.ac.uk/id/eprint/196543/
https://doi.org/10.1016/j.cellsig.2020.109638

المؤلفون: Spender, Lindsay C, Whiteman, Hannah J, Karstegl, Claudio Elgueta, Farrell, Paul J

المصدر: Oncogene ; volume 24, issue 11, page 1873-1881 ; ISSN 0950-9232 1476-5594

الاتاحة: http://dx.doi.org/10.1038/sj.onc.1208404
https://www.nature.com/articles/1208404.pdf
https://www.nature.com/articles/1208404