المؤلفون: Adrian D. Matthews, Ellyn Peters, John S. Debenham, Qi Gao, Maya D. Nyamiaka, Jianping Pan, Li-Kang Zhang, Spencer D. Dreher, Shane W. Krska, Matthew S. Sigman, Mycah R. Uehling

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Sociology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, multiple time points, demonstrate broad generality, complex aryl halides, build statistical models, aryl halides promoted, consistent data sets, oxamate ligand system, improved reaction performance, data science synthesis, investigating ligand function, branched aryl amines, stage library synthesis, used miniaturized hte, ligand features, cu oxamate, branched amines, throughput experimentation, substrate scope, rapid production, provided insight

Relation: https://figshare.com/articles/journal_contribution/Cu_Oxamate-Promoted_Cross-Coupling_of_Branched_Amines_and_Complex_Aryl_Halides_Investigating_Ligand_Function_through_Data_Science/24749091

الاتاحة: https://doi.org/10.1021/acscatal.3c04566.s003
https://figshare.com/articles/journal_contribution/Cu_Oxamate-Promoted_Cross-Coupling_of_Branched_Amines_and_Complex_Aryl_Halides_Investigating_Ligand_Function_through_Data_Science/24749091

المؤلفون: Spencer D. Dreher (1317162), Shane W. Krska (1339053)

مصطلحات موضوعية: Sociology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, nanoscale chemistry approaches, chemistry Informer Libraries, nonstandardized test molecules, substrate, PCA, data generation workflow, method, synthesis, principle component analysis, 1536- well-plate nanoscale reaction., reaction conditions

Relation: https://figshare.com/articles/journal_contribution/Chemistry_Informer_Libraries_Conception_Early_Experience_and_Role_in_the_Future_of_Cheminformatics/14224032

الاتاحة: https://doi.org/10.1021/acs.accounts.0c00760.s001

المؤلفون: Cesar N. Prieto Kullmer, Jacob A. Kautzky, Shane W. Krska, Timothy Nowak, Spencer D. Dreher, David W. C. MacMillan

المصدر: Science

مصطلحات موضوعية: Multidisciplinary, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7dedbb311cdaed9d29c74bd68fb545
https://doi.org/10.1126/science.abn1885

المؤلفون: Shishi Lin, Spencer D. Dreher, Michael K. Wismer, Ning Qi, Shane W. Krska, Donald V. Conway

المصدر: Reaction Chemistry & Engineering. 7:354-360

مصطلحات موضوعية: Fluid Flow and Transfer Processes, Materials science, Chemistry (miscellaneous), business.industry, Process Chemistry and Technology, High-throughput screening, Chemical Engineering (miscellaneous), Optoelectronics, business, Catalysis, Intensity (heat transfer)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::16020e6c46d5b6657646423d7bef5aa7
https://doi.org/10.1039/d1re00317h

المؤلفون: Marion H. Emmert, Melodie Christensen, Daniel A. DiRocco, Spencer D. Dreher, David C. Isom, Rosanne Isom, Michael Shevlin

المصدر: ACS Symposium Series ISBN: 9780841297579

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7ba69a882629a088693f9226f3919e10
https://doi.org/10.1021/bk-2022-1419.ch006

المؤلفون: Spencer D. Dreher, Shane W. Krska

المصدر: Accounts of Chemical Research. 54:1586-1596

مصطلحات موضوعية: Scope (project management), 010405 organic chemistry, Test data generation, business.industry, Usability, General Medicine, General Chemistry, Space (commercial competition), 010402 general chemistry, 01 natural sciences, Data science, 0104 chemical sciences, Workflow, Cheminformatics, Relevance (information retrieval), Chemistry (relationship), business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a60e10bec65da84eb21319c184dd9e
https://doi.org/10.1021/acs.accounts.0c00760

المؤلفون: Spencer D. Dreher, Michael R. Maser, Klavs F. Jensen, Abigail G. Doyle, Michael Wleklinski, Anton Kast, Steven Kearnes, Connor W. Coley, Joel M. Hawkins

مصطلحات موضوعية: Downstream (software development), Database, Emerging technologies, Chemistry, General Chemistry, Information repository, computer.software_genre, External Data Representation, Biochemistry, Structuring, Catalysis, Schema (genetic algorithms), Data sharing, Colloid and Surface Chemistry, User interface, computer

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6438fc1ea7b025adab5183dd9c46ccc8
https://resolver.caltech.edu/CaltechAUTHORS:20211122-234818109

المؤلفون: Spencer D. Dreher, David W. C. MacMillan, Jacob A. Kautzky, Shane W. Krska, Timothy Nowak, Cesar N. Prieto Kullmer

مصطلحات موضوعية: Generality, Scope (project management), Computer science, Generalization, Phenotypic screening, Contrast (statistics), Biochemical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89229345025daddecca6f698b74d28a1
https://doi.org/10.33774/chemrxiv-2021-8f5ws

المؤلفون: Abigail G. Doyle, Spencer D. Dreher, Jesús G. Estrada, Shishi Lin, Derek T. Ahneman

المصدر: Science. 360:186-190

مصطلحات موضوعية: Coupling, Multidisciplinary, 010405 organic chemistry, business.industry, Value (computer science), 010402 general chemistry, Machine learning, computer.software_genre, 01 natural sciences, Chemical space, 0104 chemical sciences, Random forest, Linear regression, Artificial intelligence, business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0c32cdb75279e8c9fac1d2f9dbca56ad
https://doi.org/10.1126/science.aar5169

المؤلفون: Marion H. Emmert, Matthieu Jouffroy, David C. Leitch, Simon Berritt, Melodie Christensen, Magnus J. Johansson, Shane W. Krska, Stephen G. Newman, Jessica Sampson, Eric M. Simmons, Ying Wang, Neil A. Strotman, Iulia I. Strambeanu, Justin B. Diccianni, C. Liana Allen, Kelsey F. VanGelder, Courtney K. Maguire, Nessa Carson, Daniel A. DiRocco, Spencer D. Dreher, David C. Isom, Rosanne Isom, Michael Shevlin, Alexandra C. Sun, Corey R. J. Stephenson, Robert T. Kennedy, Carla Casadevall, Jordi Aragón, Santiago Cañellas, Miquel A. Pericàs, Julio Lloret-Fillol, Xisco Caldentey, Jonas Rein, Song Lin, Dipannita Kalyani, Dan Lehnherr, Noah P Tu, Brian J. Kotecki

Resource Type: eBook.

الموضوعات: Combinatorial chemistry, Pharmaceutical chemistry, High throughput screening (Drug development), Biopharmaceutics

Categories: TECHNOLOGY & ENGINEERING / Chemical & Biochemical

المؤلفون: Spencer D. Dreher, R. Thomas Williamson, Neil C. Tomson, Mengnan Zhang, Samuel P. McCollom, Sonia Montel, Jianyou Mao, Christopher J. Welch, Brian C. Manor, Erik L. Regalado, Tiezheng Jia, Ana Bellomo, Patrick J. Walsh

المصدر: Journal of the American Chemical Society. 139:8337-8345

مصطلحات موضوعية: inorganic chemicals, chemistry.chemical_element, SULFOXIDE, 010402 general chemistry, 01 natural sciences, Biochemistry, Medicinal chemistry, Catalysis, chemistry.chemical_compound, Transmetalation, Colloid and Surface Chemistry, Bromide, ENANTIOSELECTIVE, Organic chemistry, Moiety, JOSIPHOS, 010405 organic chemistry, Chemistry, Otras Ciencias Químicas, Aryl, Ciencias Químicas, Enantioselective synthesis, General Chemistry, Oxidative addition, 0104 chemical sciences, CIENCIAS NATURALES Y EXACTAS, Palladium

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c3d190fc288b63cb74b385a8f207e0
https://doi.org/10.1021/jacs.7b03623

المؤلفون: Spencer D. Dreher, John A. Ragan

المصدر: The Journal of organic chemistry. 84(8)

مصطلحات موضوعية: chemistry.chemical_compound, Engineering management, Chemistry, Excellence, media_common.quotation_subject, Organic Chemistry, Organic synthesis, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b28938bdb528f327bff8b13b25b4da
https://pubmed.ncbi.nlm.nih.gov/30999757

المؤلفون: Daniel A. DiRocco, David W. C. MacMillan, Stephen L. Buchwald, Spencer D. Dreher, Ian W. Davies, Michael T. Pirnot, Emily B. Corcoran, Shishi Lin

المساهمون: Massachusetts Institute of Technology. Department of Chemistry, Pirnot, Michael T, Buchwald, Stephen Leffler

المصدر: PMC

مصطلحات موضوعية: Multidisciplinary, Natural product, 010405 organic chemistry, Ligand, Aryl, chemistry.chemical_element, Halide, Photoredox catalysis, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, Article, Reductive elimination, 0104 chemical sciences, Metal, Nickel, chemistry.chemical_compound, chemistry, visual_art, visual_art.visual_art_medium, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2784315b681ce0925f14a9944174eea
https://doi.org/10.1126/science.aag0209

المؤلفون: Varsolona Richard J, Jeremy P. Scott, Andrew W. Gibson, Lorenzo Codan, Xianliang He, Sophie Strickfuss, Lushi Tan, Alfred Y. Lee, Feng Wen, Wei Lin, Mark McLaughlin, Stephen P. Keen, Qinghao Chen, David R. Lieberman, Guiquan Liu, Mikhail Reibarkh, Spencer D. Dreher, Yan Jin, Michael Williams, Renee K. Dermenjian

المصدر: Organic Process Research & Development. 20:1227-1238

مصطلحات موضوعية: Active ingredient, 010405 organic chemistry, Chemistry, Stereochemistry, Process development, Organic Chemistry, Process improvement, 010402 general chemistry, 01 natural sciences, Borylation, 0104 chemical sciences, chemistry.chemical_compound, Physical and Theoretical Chemistry, NS5B, Boronic acid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::faa863929f3ac296401789ae4c0011ea
https://doi.org/10.1021/acs.oprd.5b00405

المؤلفون: Spencer D. Dreher, Shishi Lin, William D. Blincoe, Huaming Sheng

المصدر: Tetrahedron. 76:131434

مصطلحات موضوعية: Routine screening, 010405 organic chemistry, Chemistry, Organic Chemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, Method development, Chemical reaction, Small molecule, 0104 chemical sciences, Matrix-assisted laser desorption/ionization, Drug Discovery, Profiling (information science), Screening tool, Biochemical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::879c245a38a325a0a516c008215c0ef0
https://doi.org/10.1016/j.tet.2020.131434

المؤلفون: Spencer D. Dreher, Nicholas K. Terrett, Emma R. Parmee, Matthew D. Truppo, Richard D. Tillyer, Robert M. Garbaccio, Kevin R. Campos, Juan C. Alvarez, Paul J. Coleman

المصدر: Science (New York, N.Y.). 363(6424)

مصطلحات موضوعية: Drug Industry, Emerging technologies, Photochemistry, Chemistry, Pharmaceutical, Mature technology, 010402 general chemistry, Chemist, 01 natural sciences, Machine Learning, Inventions, Drug Discovery, Pharmaceutical industry, Multidisciplinary, 010405 organic chemistry, Drug discovery, business.industry, Biosynthetic Chemistry, Chemical space, 0104 chemical sciences, Enzymes, High-Throughput Screening Assays, Pharmaceutical Preparations, Cheminformatics, Biocatalysis, Biochemical engineering, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4944906dcdf6c76e77faf1e97bcee336
https://pubmed.ncbi.nlm.nih.gov/30655413

المؤلفون: Huaming Sheng, Shishi Lin, Tim Cernak, Christopher J. Welch, Kerstin Zawatzky, William D. Blincoe, Ian W. Davies, Zhengwei Peng, Ron Ferguson, Robert P. Sheridan, Sergei Dikler, Daniel A. DiRocco, Spencer D. Dreher, Heather Wang, Donald V. Conway

المصدر: Science. 361

مصطلحات موضوعية: Protocol (science), Multidisciplinary, 010405 organic chemistry, Process (engineering), Photoredox catalysis, 010402 general chemistry, 01 natural sciences, Chemical reaction, Coupling reaction, 0104 chemical sciences, Structural element, Identification (information), Lead (geology), Biochemical engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61431e9cc955e0f2d7412a6d8da3428
https://doi.org/10.1126/science.aar6236

المؤلفون: Spencer D. Dreher, Derek T. Ahneman, Abigail G. Doyle, Jesús G. Estrada, Robert P. Sheridan

المصدر: Science (New York, N.Y.). 362(6416)

مصطلحات موضوعية: Coupling, Multidisciplinary, 010405 organic chemistry, business.industry, Computer science, 010402 general chemistry, Machine learning, computer.software_genre, 01 natural sciences, 0104 chemical sciences, Machine Learning, Models, Chemical, Artificial intelligence, business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60af36977685cde52663790cfd38ce18
https://pubmed.ncbi.nlm.nih.gov/30442776

المؤلفون: Jianyou Mao, Jiadi Zhang, Hui Jiang, Ana Bellomo, Mengnan Zhang, Zidong Gao, Spencer D. Dreher, Patrick J. Walsh

المصدر: Angewandte Chemie. 128:2572-2576

مصطلحات موضوعية: 010405 organic chemistry, General Medicine, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6e80287020c4c382eea8441eec26308c
https://doi.org/10.1002/ange.201509917

المؤلفون: Daniel A. DiRocco, Bing Li, Spencer D. Dreher, Shane W. Krska, Tim Cernak, Eric Streckfuss, Peter S. Kutchukian, Ian W. Davies, Petr Vachal, James F. Dropinski, Louis-Charles Campeau, Kevin D. Dykstra

المصدر: Chem. Sci.. 7:2604-2613

مصطلحات موضوعية: 010405 organic chemistry, Chemistry, business.industry, Nanotechnology, General Chemistry, 010402 general chemistry, Machine learning, computer.software_genre, 01 natural sciences, 0104 chemical sciences, Visualization, Cheminformatics, Artificial intelligence, Chemistry (relationship), business, computer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3bcd64675da33d4e536cbac82c269c4b
https://doi.org/10.1039/c5sc04751j