المؤلفون: Antonina V. Kurtova, Melanie Heinlein, Simon Haas, Lars Velten, Gerrit J. P. Dijkgraaf, Elaine E. Storm, Noelyn M. Kljavin, Soufiane Boumahdi, Patricia Himmels, Aurelie Herault, Andrew Mancini, Hartmut Koeppen, Monique Dail, Qingxiang Yan, Jianhuan Zhang, Ute Koch, Freddy Radtke, Zora Modrusan, Ciara Metcalfe, Robert Piskol, Frederic J. de Sauvage

مصطلحات موضوعية: Cancer Research, wnt/beta-catenin, lgr5, ligands, receptors, beta-catenin, differentiation, Hematology, Stem cells, Hematopoiesis, wnt pathway, zonation, Hematopoesi, activation, Molècules, Cèl·lules mare, mouse

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b308255afe28c772497cb21827be407c
http://edoc.mdc-berlin.de/21971/2/21971suppl.pdf

المؤلفون: Frederic J. de Sauvage, Soufiane Boumahdi

المصدر: Nature Reviews Drug Discovery. 19:39-56

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Cell Plasticity, Antineoplastic Agents, Drug resistance, Biology, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Drug Discovery, Tumor Microenvironment, medicine, Humans, Basal cell carcinoma, Molecular Targeted Therapy, Pharmacology, Melanoma, General Medicine, medicine.disease, Phenotype, 030104 developmental biology, Tumor Escape, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, Adenocarcinoma, Reprogramming

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e05c24dad8fc69a36cab49e317a5b3
https://doi.org/10.1038/s41573-019-0044-1

المؤلفون: Frederic J. de Sauvage, Stephen E. Gould, Gerrit J. P. Dijkgraaf, Franklin Peale, Soufiane Boumahdi, Brian Biehs, Bruno Alicke, Robert Piskol

المصدر: Nature. 562:429-433

مصطلحات موضوعية: 0301 basic medicine, Multidisciplinary, Wnt signaling pathway, Vismodegib, Biology, medicine.disease, Hedgehog signaling pathway, 03 medical and health sciences, 030104 developmental biology, Cancer cell, Cancer research, medicine, Basal cell carcinoma, Stem cell, Smoothened, Reprogramming, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f27efd049b599d0ab2b873636c5fa4c1
https://doi.org/10.1038/s41586-018-0596-y

المؤلفون: Ievgenia Pastushenko, Federico Sopena, Virginie Moers, Audrey Brisebarre, Angel Lanas, Soufiane Boumahdi, Cédric Blanpain, Isabelle Salmon, Marco Fioramonti, Cédric Balsat, Jean-Christophe Marine, Youri Sokolow, Sarah De Clercq, Panagiota A. Sotiropoulou, Samuel Scozzaro, Alejandro Sifrim, Alexandra Van Keymeulen, Florian De Cock, Christine Dubois, Tatiana Revenco, Esmeralda Minguijón, Thierry Voet, Daniel Brown, Nicky D'Haene, Sophie Lemaire

المصدر: Nature. 556:463-468

مصطلحات موضوعية: Male, 0301 basic medicine, Cell signaling, Epithelial-Mesenchymal Transition, Skin Neoplasms, Transcription, Genetic, Tumour heterogeneity, Cell, Gene regulatory network, Mammary Neoplasms, Animal, Biology, Epigenesis, Genetic, Metastasis, Mesoderm, Mice, 03 medical and health sciences, Neoplasms, medicine, Animals, Humans, Gene Regulatory Networks, Neoplasm Invasiveness, Epigenetics, Neoplasm Metastasis, Transcription factor, Regulation of gene expression, Multidisciplinary, Epithelial Cells, medicine.disease, Chromatin, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, embryonic structures, Cancer research, Female, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a960807e419e524687a9ba4aaa5404b6
https://doi.org/10.1038/s41586-018-0040-3

المؤلفون: Christine Dubois, Erwin Nkusi, Sandrine Rorive, Soufiane Boumahdi, Gregory Driessens, Cédric Blanpain, François Fuks, Isabelle Salmon, Benjamin Delatte, Sylvain Brohée, Benjamin Beck, Amélie Caauwe, Gaëlle Lapouge, Marie Le Mercier, Véronique Del Marmol, Sandrine Lenglez, Dany Nassar

المصدر: Nature. 511:246-250

مصطلحات موضوعية: Multidisciplinary, fungi, Human skin, Biology, medicine.disease_cause, Embryonic stem cell, Transplantation, stomatognathic system, SOX2, Cancer stem cell, embryonic structures, Cancer cell, Immunology, medicine, Cancer research, sense organs, Carcinogenesis, Adult stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::01c67bf00ebeb757dea7ba18cc99bfd9
https://doi.org/10.1038/nature13305

المؤلفون: Rui Yi, Audrey Brisebarre, Agnieszka Checinska, Alizée Vercauteren Drubbel, Erwin Nkusi, Soufiane Boumahdi, Sandrine Lenglez, Christine Dubois, Michael Devos, Benjamin Beck, Mathilde Latil, Cédric Blanpain, Li Wang, Dany Nassar, Wim Declercq

المصدر: Cell stem cell, 20 (2

مصطلحات موضوعية: 0301 basic medicine, Skin Neoplasms, Transcription, Genetic, Carcinogenesis, Cellular differentiation, gene regulatory network, medicine.disease_cause, cancer cell of origin, Epigenesis, Genetic, Mice, cellular reprogramming, tumor heterogeneity, cancer cell plasticity, Neoplasm Metastasis, Epigenomics, skin cancer, EMT, Cell Differentiation, Sciences bio-médicales et agricoles, Chromatin, Editorial, embryonic structures, Carcinoma, Squamous Cell, Neoplastic Stem Cells, Molecular Medicine, Hair Follicle, epigenetic, Epithelial-Mesenchymal Transition, Biology, 03 medical and health sciences, transcription factors, Genetics, medicine, Animals, Humans, Cell Lineage, Epithelial–mesenchymal transition, Epigenetics, Transcription factor, Base Sequence, Epithelial Cells, Cell Biology, Phosphoproteins, Clone Cells, Repressor Proteins, 030104 developmental biology, HEK293 Cells, Cancer cell, Immunology, Cancer research, Trans-Activators

وصف الملف: 2 full-text file(s): application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ebd28d06492300f594cf5f17a53a26
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/241437

المؤلفون: Soufiane, Boumahdi, Cédric, Blanpain

المصدر: Science (New York, N.Y.). 351(6272)

مصطلحات موضوعية: Gene Expression Regulation, Neoplastic, Skin Neoplasms, Carcinogenesis, Neural Crest, Melanoma, Experimental, Animals, Gene Expression Regulation, Developmental, Melanoma, Zebrafish, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9648eaa8fd427c052d1fc54513b164ef
https://pubmed.ncbi.nlm.nih.gov/26823433

المؤلفون: Cédric Blanpain, Soufiane Boumahdi

المصدر: Science. 351:453-454

مصطلحات موضوعية: 0301 basic medicine, Multidisciplinary, Transgene, Cancer, Tumor initiation, Biology, medicine.disease_cause, medicine.disease, Tumor formation, 03 medical and health sciences, 030104 developmental biology, Cancer cell, Cancer research, medicine, Progenitor cell, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4773df7f503d022f8fd5f5b3c6d49f90
https://doi.org/10.1126/science.aad9670