المؤلفون: Rebecca Nofsinger, Sophie-Dorothee Clas, Rosa I. Sanchez, Abbas Walji, Kimberly Manser, Becky Nissley, Jaume Balsells, Amrithraj Nair, Qun Dang, David Jonathan Bennett, Michael Hafey, Junying Wang, John Higgins, Allen Templeton, Paul Coleman, Jay Grobler, Ronald Smith, Yunhui Wu

المصدر: Pharmaceuticals, Vol 7, Iss 2, Pp 207-219 (2014)

مصطلحات موضوعية: prodrugs, colonic absorption, dog colonic studies, enabling QD dosing, chemistry-enabled drug delivery, enhancing lipophilicity, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1424-8247/7/2/207; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/f16659dde48e4fc4a5f8d5c963902bbd

المؤلفون: Yuan Gao, Jieyu Zuo, Nadia Bou-Chacra, Terezinha de Jesus Andreoli Pinto, Sophie-Dorothee Clas, Roderick B. Walker, Raimar Löbenberg

المصدر: BioMed Research International, Vol 2013 (2013)

مصطلحات موضوعية: Medicine

Relation: http://dx.doi.org/10.1155/2013/136590; https://doaj.org/toc/2314-6133; https://doaj.org/toc/2314-6141; https://doaj.org/article/963f455f9a944e3d8af3a558c07517c7

الاتاحة: https://doi.org/10.1155/2013/136590
https://doaj.org/article/963f455f9a944e3d8af3a558c07517c7

المؤلفون: Sophie-Dorothee Clas, Gabriella Costabile, Ricky D. Wildman, Amina Faham, Olivia M. Merkel, Juergen Siepmann, Christine Allen, James C. Evans, Vincent Jannin, Ben J. Boyd, Hang Zhao, Jean-Christophe Leroux, Andreas Bernkop-Schnürch, Morgan R. Alexander, Clive J. Roberts, Sébastien Lecommandoux

المساهمون: Institut National de la Santé et de la Recherche Médicale (INSERM), University Hospital of Lille, DuPont Health & Nutrition, PharmaSolv Consulting, Monash Institute of Pharmaceutical Science, Gattefossé SAS, Gattefossé, Leopold Franzens Universität Innsbruck - University of Innsbruck, Laboratoire de Chimie des Polymères Organiques (LCPO), Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC), Team 3 LCPO : Polymer Self-Assembly & Life Sciences, Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Institut Polytechnique de Bordeaux-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Université de Bordeaux (UB)-Institut de Chimie du CNRS (INC), Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canada, 9Department of Biochemistry, Faculty of Medicine, University of Toronto, Ludwig Maximilian University [Munich] (LMU), University of Nottingham, UK (UON), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-Ecole Nationale Supérieure de Chimie, de Biologie et de Physique (ENSCBP)-Institut Polytechnique de Bordeaux-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Sandre, Olivier, Siepmann, Juergen, Faham, Amina, Clas, Sophie-Dorothée, Boyd, Ben J, Jannin, Vincent, Bernkop-Schnürch, Andrea, Zhao, Hang, Lecommandoux, Sébastien, Evans, James C, Allen, Christine, Merkel, Olivia M, Costabile, Gabriella, Alexander, Morgan R, Wildman, Ricky D, Roberts, Clive J, Leroux, Jean-Christophe

المصدر: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2019, 558, pp.128-142. ⟨10.1016/j.ijpharm.2018.12.080⟩
International Journal of Pharmaceutics, 2019, 558, pp.128-142. ⟨10.1016/j.ijpharm.2018.12.080⟩
International Journal of Pharmaceutics, 558

مصطلحات موضوعية: Polymers, Pharmaceutical Science, Administration, Oral, Polymersome, 02 engineering and technology, 030226 pharmacology & pharmacy, Drug formulations, Dosage form, Nanoparticle, 0302 clinical medicine, solid dispersions, sustained release, Polymer, Drug Carrier, Active ingredient, chemistry.chemical_classification, Dosage Forms, Drug Carriers, Chemistry, Pillar, Self-emulsifying drug delivery system, 3D printing, [CHIM.MATE]Chemical Sciences/Material chemistry, Lipid, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, 021001 nanoscience & nanotechnology, Lipids, Liposome, [SDV.SP] Life Sciences [q-bio]/Pharmaceutical sciences, Peptide, Printing, Three-Dimensional, 0210 nano-technology, [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], Human, liposomes, [CHIM.POLY] Chemical Sciences/Polymers, Solid dispersion, Nanotechnology, self-emulsifying drug delivery systems, Excipients, 03 medical and health sciences, Excipient, Pharmaceutical technology, Animals, Humans, Technology, Pharmaceutical, Dosage Form, gene delivery, [CHIM.MATE] Chemical Sciences/Material chemistry, Animal, Solid dispersions, Self-emulsifying drug delivery systems, Sustained release, Liposomes, Polymersomes, Peptides, Gene delivery, 3D Printing, [PHYS.COND.CM-SCM] Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], [CHIM.POLY]Chemical Sciences/Polymers, polymersomes, peptides, Nanoparticles

وصف الملف: application/pdf; application/application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6f1a7e135a0c83474a41ba5a3b5126
https://hal.archives-ouvertes.fr/hal-01978128

المؤلفون: Wilson Roa, Sophie-Dorothee Clas, Yuan Gao, Muhammad Sarfraz, Raimar Löbenberg

المصدر: Journal of Biomedical Nanotechnology. 11:1312-1329

مصطلحات موضوعية: Cell Survival, medicine.medical_treatment, alpha-Tocopherol, Antitubercular Agents, Biomedical Engineering, Pharmaceutical Science, Medicine (miscellaneous), Bioengineering, Endocytosis, Micelle, Nanocapsules, Cell Line, Diffusion, Mice, chemistry.chemical_compound, Macrophages, Alveolar, Hyaluronic acid, polycyclic compounds, medicine, Animals, heterocyclic compounds, General Materials Science, Hyaluronic Acid, Particle Size, Micelles, Chemistry, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Cytokine, Cell culture, Delayed-Action Preparations, Alveolar macrophage, Biophysics, Cytokines, bacteria, Rifampin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93715b44e646e6888b58ac7984526e13
https://doi.org/10.1166/jbn.2015.2091

المؤلفون: Paul J. Coleman, Becky Nissley, Allen C. Templeton, Yunhui Wu, Rosa I. Sanchez, Jaume Balsells, Jay A. Grobler, Sophie-Dorothee Clas, Michael J. Hafey, Junying Wang, Abbas Walji, Qun Dang, Rebecca Nofsinger, Jing Li, Manuel de Lera Ruiz, Gene Chessen, John M. Sanders, Christopher T. John, Amrithraj Bennet, John S. Wai, David Jonathan Bennett, Kimberly Manser, Christina N. Di Marco, Scott S. Ceglia, Somang Hope Kim, John Higgins, Ronald D. Smith

المصدر: ChemMedChem. 10:245-252

مصطلحات موضوعية: Male, Carbonates, Drug Evaluation, Preclinical, HIV Integrase, Pyrimidinones, Pharmacology, Biochemistry, Structure-Activity Relationship, Acetals, Dogs, Pharmacokinetics, In vivo, Raltegravir Potassium, Drug Discovery, medicine, Animals, Humans, Prodrugs, HIV Integrase Inhibitors, Intestinal Mucosa, Rats, Wistar, General Pharmacology, Toxicology and Pharmaceutics, Oxadiazoles, biology, Chemistry, Drug discovery, Organic Chemistry, Prodrug, Raltegravir, Small molecule, Pyrrolidinones, Rats, Integrase, ROC Curve, Tolerability, Area Under Curve, HIV-1, Hepatocytes, biology.protein, Molecular Medicine, Half-Life, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8eaf7e17f0b6021ac4c02ad8253c13
https://doi.org/10.1002/cmdc.201402393

المؤلفون: Abbas Walji, Becky Nissley, Michael J. Hafey, Jay A. Grobler, Rosa I. Sanchez, Jaume Balsells, John Higgins, Allen C. Templeton, Ronald D. Smith, Paul J. Coleman, David Jonathan Bennett, Kimberly Manser, Qun Dang, Sophie-Dorothee Clas, Rebecca Nofsinger, Amrithraj Nair, Yunhui Wu, Junying Wang

المصدر: Pharmaceuticals
Pharmaceuticals; Volume 7; Issue 2; Pages: 207-219
Pharmaceuticals, Vol 7, Iss 2, Pp 207-219 (2014)

مصطلحات موضوعية: Absorption (pharmacology), lcsh:Medicine, lcsh:RS1-441, Pharmaceutical Science, Pharmacology, Article, lcsh:Pharmacy and materia medica, prodrugs, colonic absorption, dog colonic studies, enabling QD dosing, chemistry-enabled drug delivery, enhancing lipophilicity, Pharmacokinetics, In vivo, Drug Discovery, Solubility, Chemistry, lcsh:R, Prodrug, Combinatorial chemistry, Biopharmaceutical, Lipophilicity, Drug delivery, Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82703542f99decf50128201918231f4
http://europepmc.org/articles/PMC3942693

المؤلفون: Rebecca Nofsinger, Sophie-Dorothee Clas, Rosa I. Sanchez

المصدر: Drug Discovery Today. 19:79-87

مصطلحات موضوعية: Pharmacology, Drug, Active ingredient, Clinical Trials as Topic, media_common.quotation_subject, Nanotechnology, Prodrug, Drug molecule, Drug Delivery Systems, Biopharmaceutical, Pharmaceutical Preparations, Risk analysis (engineering), Drug Discovery, Drug delivery, Animals, Humans, Prodrugs, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74ec5d319f6c2239844b3ebbd84588a
https://doi.org/10.1016/j.drudis.2013.08.014

المؤلفون: Elizabeth Kwong, Raj Suryanarayanan, Allen C. Templeton, Kapildev K. Arora, Sunny P. Bhardwaj, Sophie-Dorothee Clas

المصدر: Molecular Pharmaceutics. 10:694-700

مصطلحات موضوعية: Arrhenius equation, Materials science, Chromatography, Kinetics, Pharmaceutical Science, Thermodynamics, Atmospheric temperature range, Instability, Isothermal process, Dielectric spectroscopy, Amorphous solid, symbols.namesake, Drug Discovery, symbols, Molecular Medicine, Itraconazole, Crystallization, Supercooling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec2a8a611a381184dd3565d4f33db64
https://doi.org/10.1021/mp300487u

المؤلفون: Wilson Roa, Raimar Löbenberg, Yuan Gao, Wenjun Shi, Muhammad Sarfraz, Nadia Araci Bou-Chacra, Sophie-Dorothee Clas

المصدر: Therapeutic delivery. 7(4)

مصطلحات موضوعية: inorganic chemicals, 0301 basic medicine, Materials science, food.ingredient, Drug Liberation, Cell Survival, Moxifloxacin, Antitubercular Agents, Pharmaceutical Science, Enzyme-Linked Immunosorbent Assay, 02 engineering and technology, Pharmacology, Gelatin, Microbiology, Cell Line, 03 medical and health sciences, Mice, food, Immune system, Microscopy, Electron, Transmission, mental disorders, medicine, Macrophage, Animals, Tuberculosis, Cyanoacrylates, health care economics and organizations, Chromatography, High Pressure Liquid, Drug Carriers, Macrophages, technology, industry, and agriculture, respiratory system, Enbucrilate, 021001 nanoscience & nanotechnology, Dynamic Light Scattering, 030104 developmental biology, Cell culture, Toxicity, Cytokines, Nanoparticles, Spectrophotometry, Ultraviolet, Rifampin, 0210 nano-technology, Drug carrier, medicine.drug, Fluoroquinolones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efbfd6df40fb27b16ca19d9af3f9600
https://pubmed.ncbi.nlm.nih.gov/27075954

المؤلفون: Ivan Santos, Roy Helmy, Elizabeth Kwong, Robert Wenslow, and Chad Dalton, Narayan Variankaval, Robert Hartman, Sophie-Dorothee Clas, Jerry A. Murry

المصدر: Crystal Growth & Design. 6:690-700

مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, Carboxylic acid, Free base, General Chemistry, Condensed Matter Physics, Combinatorial chemistry, Cocrystal, Bioavailability, chemistry.chemical_compound, chemistry, Tartaric acid, Molecule, General Materials Science, Acid–base reaction, Isostructural

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c7a3b02bb1f41686777f8bb26cf98850
https://doi.org/10.1021/cg050462u

المؤلفون: Jean-Michel Rabanel, Véronique Nadeau, Sophie-Dorothee Clas, Shilpa Sant, Roula Chahwan, Patrice Hildgen

المصدر: Journal of Applied Polymer Science. 102:2568-2577

مصطلحات موضوعية: chemistry.chemical_classification, Conductive polymer, Condensation polymer, Materials science, Polymers and Plastics, Biocompatibility, General Chemistry, Polymer, Surfaces, Coatings and Films, Contact angle, Thermogravimetry, Crystallinity, chemistry.chemical_compound, Monomer, chemistry, Polymer chemistry, Materials Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::790fd58281c85da270e015f402af5c24
https://doi.org/10.1002/app.24686

المؤلفون: Patrick M Gosselin, Sophie-Dorothee Clas, François-Xavier Lacasse, Michel Preda, Jean Norbert Mcmullen, Roch Thibert

المصدر: Pharmaceutical Development and Technology. 8:11-20

مصطلحات موضوعية: Thermogravimetric analysis, Chromatography, Differential scanning calorimetry, Chemical engineering, Scanning electron microscope, Chemistry, Spray drying, Pharmaceutical Science, General Medicine, Particle size, Micronization, Microparticle, Supercritical fluid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::30eea28f7091085ce1ddb7277f87bf37
https://doi.org/10.1081/pdt-120017519

المؤلفون: Sophie-Dorothee Clas, Sunny P. Bhardwaj, Kapildev K. Arora, Allen C. Templeton, Elizabeth Kwong, Raj Suryanarayanan

المصدر: Molecular pharmaceutics. 11(11)

مصطلحات موضوعية: Materials science, Kinetics, Pharmaceutical Science, Methylcellulose, law.invention, Drug Stability, X-Ray Diffraction, law, Drug Discovery, medicine, Organic chemistry, Crystallization, chemistry.chemical_classification, Polyvinylpyrrolidone, Plasticizer, Temperature, Povidone, Polymer, Amorphous solid, Dielectric spectroscopy, Chemical engineering, chemistry, Molecular Medicine, Itraconazole, Glass transition, Synchrotrons, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a02be94e9bf1d22b6f60d77b571904
https://pubmed.ncbi.nlm.nih.gov/25325389

المؤلفون: Sophie-Dorothee Clas, Karen Christensen, Bruno C. Hancock

المصدر: International Journal of Pharmaceutics. 209:27-35

مصطلحات موضوعية: Materials science, Drug Storage, Pharmaceutical Science, Mineralogy, Young's modulus, Elasticity, Excipients, Microcrystalline cellulose, symbols.namesake, chemistry.chemical_compound, Microcrystalline, Fracture toughness, chemistry, Hardness, symbols, Relative humidity, Powders, Composite material, Elasticity (economics), Cellulose, Porosity, Algorithms, Stress intensity factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e675fb6aa63fee7d9c0b0e13f4f87f
https://doi.org/10.1016/s0378-5173(00)00541-x

المؤلفون: Karine Khougaz, Sophie-Dorothee Clas

المصدر: Journal of Pharmaceutical Sciences. 89:1325-1334

مصطلحات موضوعية: chemistry.chemical_classification, technology, industry, and agriculture, Pharmaceutical Science, macromolecular substances, Polymer, Miscibility, law.invention, chemistry.chemical_compound, Differential scanning calorimetry, chemistry, law, Polymer chemistry, Vinyl acetate, Copolymer, Crystallization, Drug carrier, Glass transition, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00605d65194d40150d213adf23941584
https://doi.org/10.1002/1520-6017(200010)89:10<1325::aid-jps10>3.0.co;2-5

المؤلفون: Bruno C. Hancock, Chad Dalton, Sophie-Dorothee Clas

المصدر: Pharmaceutical Science & Technology Today. 2:311-320

مصطلحات موضوعية: Differential scanning calorimetry, Materials science, Drug development, Pharmaceutical Science, Nanotechnology, Thermal analysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1fe3d9040dcb917cd577d707d50ed8
https://doi.org/10.1016/s1461-5347(99)00181-9

المؤلفون: Sophie-Dorothee Clas, Chad Dalton, Bruno C. Hancock

المصدر: Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition ISBN: 9781841848204

مصطلحات موضوعية: Engineering, business.industry, Nanotechnology, Calorimetry, Pharmaceutical sciences, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7a5057fa1d6d69f7e1b638bccbdbfcf4
https://doi.org/10.1081/e-ept4-120050206

المؤلفون: Roch Thibert, Elizabeth B. Vadas, Henryk Mach, Sophie-Dorothee Clas, Dale R. Meisner

المصدر: International Journal of Pharmaceutics. 134:59-70

مصطلحات موضوعية: Surface tension, Chromatography, Dynamic light scattering, Chemistry, Ionic strength, Critical micelle concentration, Radius of gyration, Analytical chemistry, Pharmaceutical Science, Solubility, Micelle, Light scattering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d82d345aa900e92ed3c76a0675e7e1fa
https://doi.org/10.1016/0378-5173(96)04435-3

المؤلفون: Nadia Araci Bou-Chacra, Jieyu Zuo, Sophie-Dorothee Clas, Roderick B. Walker, Terezinha de Jesus Andreoli Pinto, Raimar Löbenberg, Yuan Gao

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
BioMed Research International
BioMed Research International, Vol 2013 (2013)

مصطلحات موضوعية: food.ingredient, Article Subject, Kinetics, Antitubercular Agents, lcsh:Medicine, Nanoparticle, 02 engineering and technology, Pharmacology, Moxifloxacin hydrochloride, 030226 pharmacology & pharmacy, Gelatin, General Biochemistry, Genetics and Molecular Biology, Dialysis tubing, 03 medical and health sciences, 0302 clinical medicine, food, Drug Delivery Systems, Humans, Dissolution testing, Particle Size, Chromatography, General Immunology and Microbiology, Chemistry, lcsh:R, Regenerated cellulose, General Medicine, 021001 nanoscience & nanotechnology, Nanoparticles, Nanocarriers, Rifampin, 0210 nano-technology, ANTI-INFECCIOSOS, Research Article

وصف الملف: text/xhtml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a7f8b7000292961efa77f023134736

المؤلفون: R. E. O'Connor, Elizabeth B. Vadas, Sophie-Dorothee Clas, Rumi Faizer

المصدر: International Journal of Pharmaceutics. 121:73-79

مصطلحات موضوعية: Materials science, Calibration curve, X-ray, Pharmaceutical Science, eye diseases, Amorphous solid, Leukotriene biosynthesis, Microcrystalline cellulose, Crystallinity, chemistry.chemical_compound, Crystallography, chemistry, sense organs, Magnesium stearate, Powder diffraction, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ba88151830fde0f98f85df399bb7c580
https://doi.org/10.1016/0378-5173(95)00008-7