المؤلفون: Chao Zheng Li, Hiromi Ogawa, Soon Seng Ng, Xindi Chen, Eriko Kishimoto, Kokoro Sakabe, Aiko Fukami, Yueh-Chiang Hu, Christopher N. Mayhew, Jennifer Hellmann, Alexander Miethke, Nahrin L. Tasnova, Samuel J.I. Blackford, Zu Ming Tang, Adam M. Syanda, Liang Ma, Fang Xiao, Melissa Sambrotta, Oliver Tavabie, Filipa Soares, Oliver Baker, Davide Danovi, Hisamitsu Hayashi, Richard J. Thompson, S. Tamir Rashid, Akihiro Asai

المصدر: JHEP Reports, Vol 4, Iss 4, Pp 100446- (2022)

مصطلحات موضوعية: PFIC (progressive familial intrahepatic cholestasis), Cellular polarity, Bile acid transport, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555922000180; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/a3897953261242379e6856ff67f6e514

المؤلفون: Adam M. Syanda, Vera I. Kringstad, Samuel J. I. Blackford, Joachim S. Kjesbu, Soon Seng Ng, Liang Ma, Fang Xiao, Abba E. Coron, Anne Mari A. Rokstad, Sunil Modi, S. Tamir Rashid, Berit Løkensgard Strand

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)

مصطلحات موضوعية: sulfated alginate, cGMP, hPSC, pluripotent stem cell-derived hepatocytes, PFO, immunogenicity, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2021.816542/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/f457da41d2f843768b7ad1d228d8561c

المؤلفون: Joe M. Segal, Deniz Kent, Daniel J. Wesche, Soon Seng Ng, Maria Serra, Bénédicte Oulès, Gozde Kar, Guy Emerton, Samuel J. I. Blackford, Spyros Darmanis, Rosa Miquel, Tu Vinh Luong, Ryo Yamamoto, Andrew Bonham, Wayel Jassem, Nigel Heaton, Alessandra Vigilante, Aileen King, Rocio Sancho, Sarah Teichmann, Stephen R. Quake, Hiromitsu Nakauchi, S. Tamir Rashid

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/6bbc0c0ed8f149fd9701e5f07676f1d3

المؤلفون: John Ong, Maria Paola Serra, Joe Segal, Ana-Maria Cujba, Soon Seng Ng, Richard Butler, Val Millar, Stephanie Hatch, Salman Zimri, Hiroyuki Koike, Karen Chan, Andrew Bonham, Michelle Walk, Ty Voss, Nigel Heaton, Ragai Mitry, Anil Dhawan, Daniel Ebner, Davide Danovi, Hiromitsu Nakauchi, S. Tamir Rashid

المصدر: Stem Cell Reports, Vol 10, Iss 3, Pp 693-702 (2018)

مصطلحات موضوعية: Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671118300511; https://doaj.org/toc/2213-6711

URL الوصول: https://doaj.org/article/7c1f980085ad4d33ad10a8f4d8dd7616

المؤلفون: Samuel J.I. Blackford, Tracy T.L. Yu, Michael D.A. Norman, Adam M. Syanda, Michail Manolakakis, Dariusz Lachowski, Ziqian Yan, Yunzhe Guo, Elena Garitta, Federica Riccio, Geraldine M. Jowett, Soon Seng Ng, Santiago Vernia, Armando E. del Río Hernández, Eileen Gentleman, S. Tamir Rashid

المصدر: Gentleman, E, Rashid, T, Blackford, S, Jowett, G, Yan, Z, Yu, T, Norman, M, Guo, Y, Syanda, A, Riccio, F, Ng, S S, Manolakakis, M, Lachowski, D, Garrita, E, Vernia, S & de Rio Hernandez, A 2023, ' RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling ', Biomaterials, vol. 293, 121982 . https://doi.org/10.1016/j.biomaterials.2022.121982

مصطلحات موضوعية: Biomaterials, Mechanics of Materials, Biophysics, Ceramics and Composites, Bioengineering

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d9ea300a57246addd8c417a8dad89a
http://hdl.handle.net/10044/1/102659

المؤلفون: Helen A. B. Paterson, Sijia Yu, Natalia Artigas, Miguel A. Prado, Nejc Haberman, Yi-Fang Wang, Andrew M. Jobbins, Elena Pahita, Joao Mokochinski, Zoe Hall, Maryse Guerin, Joao A. Paulo, Soon Seng Ng, Francesc Villarroya, Sheikh Tamir Rashid, Wilfried Le Goff, Boris Lenhard, Inês Cebola, Daniel Finley, Steven P. Gygi, Christopher R. Sibley, Santiago Vernia

المصدر: Paterson, H, Yu, S, Artigas, N, Prado, M, Haberman, N, Wang, Y-F, Jobbins, A, Pahita, E, Mokochinski, J, Hall, Z, Guerin, M, Paulo, J, Ng, S S, Villarroya, F, Rashid, S T, Goff, W L, Lenhard, B, Cebola, I, Finley, D, Gygi, S, Sibley, C R & Vernia, S 2022, ' Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice ', Nature Metabolism, vol. 4, no. 12, pp. 1812-1829 . https://doi.org/10.1038/s42255-022-00681-y

مصطلحات موضوعية: Scarb1 (SR-BI/II), pre-mRNA alternative splicing, Endocrinology, Diabetes and Metabolism, RNA-Binding Proteins, MAFLD, cholesterol, Cell Biology, Scavenger Receptors, Class B, Mice, Alternative Splicing, Cholesterol, splice-switching oligonucleotide (SSO), Liver, Physiology (medical), Internal Medicine, Animals, Protein Isoforms, RNA, Homeostasis, RNA Splicing Factors, triglyceride, RBFOX2

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15b0846709fc330dbcd9cb12a59260e
https://hdl.handle.net/20.500.11820/eecc8061-8675-4351-a1e0-503b0c53cf98

المؤلفون: Guoqing Zang, Xiaohua Chen, Ting Yao, Yi Zhang, Mengjiao Lv, Soon Seng Ng

المصدر: Acta Biochimica et Biophysica Sinica. 53:643-651

مصطلحات موضوعية: 0301 basic medicine, Culture model, Cell, Cell Culture Techniques, Biophysics, 02 engineering and technology, Disease, Computational biology, Biology, Biochemistry, 03 medical and health sciences, 3D cell culture, medicine, Humans, Tissue Engineering, Tissue Scaffolds, Critical factors, Bioprinting, General Medicine, 021001 nanoscience & nanotechnology, Extracellular Matrix, Liver Transplantation, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Liver, Cell culture, Printing, Three-Dimensional, Hepatocytes, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e140aa3cc4ed7c793911c65a2ca933
https://doi.org/10.1093/abbs/gmab046

المؤلفون: Pearlyn Jia Ying Toh, Yue Zhang, Cornelia Monzel, S. Tamir Rashid, Vidhyalakshmi Acharya, Hanry Yu, Virgile Viasnoff, Jasmine Fei Li Chin, Noémi van Hul, Inn Chuan Ng, Richard De Mets, Soon Seng Ng

المصدر: Nature Materials. 19:1026-1035

مصطلحات موضوعية: Polarity (international relations), Cytoskeleton organization, Cadherin, Chemistry, Mechanical Engineering, 02 engineering and technology, General Chemistry, 010402 general chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 01 natural sciences, Embryonic stem cell, Epithelium, 0104 chemical sciences, Cell biology, Extracellular matrix, medicine.anatomical_structure, Mechanics of Materials, medicine, General Materials Science, 0210 nano-technology, Actin, Lumen (unit)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::961ba6831073c3cff3a9943f26987179
https://doi.org/10.1038/s41563-020-0662-3

المؤلفون: Deniz Kent, Soon Seng Ng, Payam Khoshkenar, Adam Syanda, Chao Zheng Li, Marina Zieger, Stephanie Hatch, Joe Segal, Samuel Blackford, Kaixing Le, Vivek Chowdary, Taylor Ismaili, Davide Danovi, Patrick Lewis, Sunil Sahdeo, Daniel Ebner, Christian Mueller, S. Tamir Rashid

مصطلحات موضوعية: nervous system diseases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb8daaf1f53f7f2962db34f88649f13a
https://doi.org/10.21203/rs.3.rs-1283764/v1

المؤلفون: Alicia J. El Haj, Soon Seng Ng, Sergi Junyent, Yoshihisa Okuchi, Shukry J. Habib, Daniel Doro, Joshua Reeves, Karen J. Liu

المصدر: Nature Materials

مصطلحات موضوعية: 02 engineering and technology, Bone healing, 010402 general chemistry, Bone tissue, 01 natural sciences, Bone and Bones, Mice, Tissue engineering, Osteogenesis, medicine, Asymmetric cell division, Animals, Humans, General Materials Science, Asymmetric stem cell division, Tissue Engineering, Chemistry, Mechanical Engineering, Stem Cells, Mesenchymal stem cell, Skull, General Chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, 0104 chemical sciences, 3. Good health, Cell biology, Wnt Proteins, medicine.anatomical_structure, Mechanics of Materials, Cortical bone, Stem cell, 0210 nano-technology, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16540ba25d3d84925128b5964239ef2b

المؤلفون: Pearlyn Jia Ying Toh, Cornelia Monzel, R. De Mets, Virgile Viasnoff, N. Van Hul, T. Rashid, Soon Seng Ng, Yi Zhang

مصطلحات موضوعية: Extracellular matrix, medicine.anatomical_structure, Polarity (international relations), Cytoskeleton organization, Cadherin, Chemistry, Cell, medicine, Embryonic stem cell, Actin, Epithelium, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc390d79f566ea498cf77bdd62ff8de
https://doi.org/10.1101/636654

المؤلفون: Yue, Zhang, Richard, De Mets, Cornelia, Monzel, Vidhyalakshmi, Acharya, Pearlyn, Toh, Jasmine Fei Li, Chin, Noémi, Van Hul, Inn Chuan, Ng, Hanry, Yu, Soon Seng, Ng, S, Tamir Rashid, Virgile, Viasnoff

المصدر: Nature materials. 19(9)

مصطلحات موضوعية: Biomimetics, Hepatocytes, Cell Polarity, Humans, Cell Line

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::491775f12dfe1d71496e42983c0838b7
https://pubmed.ncbi.nlm.nih.gov/32820290

المؤلفون: Soon Seng, Ng, Kourosh, Saeb-Parsy, Samuel J I, Blackford, Joe M, Segal, Maria Paola, Serra, Marta, Horcas-Lopez, Da Yoon, No, Sotiris, Mastoridis, Wayel, Jassem, Curtis W, Frank, Nam Joon, Cho, Hiromitsu, Nakauchi, Jeffrey S, Glenn, S Tamir, Rashid

المصدر: Biomaterials

مصطلحات موضوعية: Organogenesis, Biomimetic materials, CLF, cholyl-lysyl-flourescence, Biocompatible Materials, IH, iPSC derived hepatic progenitors, ECAM, epithelial cell adhesion molecule, HUVEC, human umbilical endothelial cell, MSC, mesenchymal stem cell, HSGP, heparin sulfate glycoprotein, Polyethylene Glycols, CLDN1, claudin 1, 2D, two-dimensional, TGFβ, transforming growth factor beta, DE, iPSC derived definitive endoderm, Cells, Cultured, Liver stem cells, AFP, alpha-fetoprotein, HNF4a, hepatocyte nuclear factor 4-alpha, Tissue Scaffolds, RNA-seq, RNA-sequence, ZO-1, tight junction protein 1, TGZ, Troglitazone, ICC, inverted colloidal crystal, OCLN, occludin, ECM, extracellular matrix, Organoids, ASGR1, asialoglycoprotein receptor 1, Liver, BSEP, bile-salt efflux pump, HCV, hepatitis C virus, LDLR, low-density lipoprotein receptor, H&E, haematoxylin and eosin, CYC, cyclopamine, Crystallization, SCARB1, scavenger receptor class B type 1, iPSC, induced pluripotent stem cell, Induced Pluripotent Stem Cells, Ln, laminin, Bioengineering, RT-qPCR, reverse transcription-quantitative polymerase chain reaction, Article, CK19, keratin 19, MRP2, multidrug resistance protein 1, Humans, ALB, albumin, PEG, polyethylene glycol, Tissue Engineering, 3D, three-dimensional, Col, collagen, PCA, principle component analysis, FDA, food and drug administration, Fn, fibronectin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::980af13431e95964b9ef5cde2da9bdcf
https://pubmed.ncbi.nlm.nih.gov/30149262

المؤلفون: Dusko Ilic, Ragai R. Mitry, Michael Sheldon, Soon Seng Ng, Sji Blackford, Ajf King, Joe M. Segal, Jennifer C. Moore, Anil Dhawan, Sheikh Tamir Rashid

مصطلحات موضوعية: Hepatic function, Scaffold, Liver therapy, Hepatic tissue, Progenitor cell, Biology, Induced pluripotent stem cell, Biocompatible material, Phenotype, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b76f40702a76b37c675a628eac12cb
https://doi.org/10.1101/298760

المؤلفون: Samuel J I, Blackford, Soon Seng, Ng, Joe M, Segal, Aileen J F, King, Amazon L, Austin, Deniz, Kent, Jennifer, Moore, Michael, Sheldon, Dusko, Ilic, Anil, Dhawan, Ragai R, Mitry, S Tamir, Rashid

المصدر: Stem Cells Translational Medicine

مصطلحات موضوعية: Pluripotent Stem Cells, iPSC, Cellular therapy, Cell Culture Techniques, Cell- and Tissue-Based Therapy, Cell Differentiation, Bioengineering, Hepatocyte differentiation, Cell Line, cGMP, Mice, Liver, hESC, Liver therapy, Hepatocytes, Animals, Humans, Cell transplantation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::7bbb4c4a724acec6e4a1d9563537dcc1
https://pubmed.ncbi.nlm.nih.gov/30456803

المؤلفون: Joe M. Segal, Deniz Kent, Hiromitsu Nakauchi, Gozde Kar, Tu Vinh, S. Tamir Rashid, Alessandra Vigilante, Samuel J.I. Blackford, Guy Emerton, Bénédicte Oulès, Ryo Yamamoto, Spyros Darmanis, Andrew Bonham, Maria Paola Serra, Daniel J. Wesche, Stephen R. Quake, Rosa Miquel, Soon Seng Ng, Sarah A. Teichmann

مصطلحات موضوعية: Liver injury, 0303 health sciences, Bile duct, Cell, Biology, medicine.disease, In vitro, Cell biology, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Single-cell analysis, 030220 oncology & carcinogenesis, Hepatocyte, medicine, Progenitor cell, 030304 developmental biology, Progenitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6b89481ebb38efb3fb460a1d579bad

المؤلفون: Amy Voedisch, Marilyn Masek, Khanh Nguyen, Mark A. Winters, Sheikh Tamir Rashid, Curtis W. Frank, Menashe Elazar, Jeffrey S. Glenn, Eyal Shteyer, Nam-Joon Cho, Soon Seng Ng, Da Yoon No, Anming Xiong, Kate Shaw

المساهمون: School of Materials Science & Engineering

المصدر: JCI Insight. 2

مصطلحات موضوعية: 0301 basic medicine, Drug, medicine.drug_class, media_common.quotation_subject, Hepatitis C virus, Fialuridine, medicine.disease_cause, Virus, 03 medical and health sciences, 0302 clinical medicine, Medicine, media_common, Hepatitis, business.industry, Liver cell, Gastroenterology, General Medicine, medicine.disease, Engineering::Materials [DRNTU], 030104 developmental biology, Technical Advance, 030220 oncology & carcinogenesis, Cancer research, Antiviral drug, business, Drug metabolism, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1c06421998affaf99f19aab1d93b25
https://doi.org/10.1172/jci.insight.90853

المؤلفون: Myung Hee Kim, Yan Wang, Soon Seng Ng, Jae Ho Lee, Nam-Joon Cho, Hitomi Shirahama, Jeffrey S. Glenn

المساهمون: School of Chemical and Biomedical Engineering, School of Materials Science & Engineering, Centre for Biomimetic Sensor Science

المصدر: Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Integrins, Scaffold, Cell Survival, Integrin, Cell Culture Techniques, 02 engineering and technology, Collagen Type I, Article, Extracellular matrix, 03 medical and health sciences, Tissue Scaffold, Albumins, Cell Line, Tumor, Occludin, Gene expression, Cytochrome P-450 CYP3A, Humans, Colloids, Cell Proliferation, Regulation of gene expression, Multidisciplinary, Tissue Scaffolds, biology, Chemistry, Cadherins, 021001 nanoscience & nanotechnology, Actins, Extracellular Matrix, Fibronectins, Cell biology, Engineering::Materials [DRNTU], Fibronectin, 030104 developmental biology, Gene Expression Regulation, Hepatocyte Nuclear Factor 4, Hepatocyte nuclear factor 4, Cell culture, Hepatocytes, biology.protein, 0210 nano-technology, Porosity

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c6707e8c60e1002324bea29114242f
https://doi.org/10.1038/srep37427

المؤلفون: Supriya K. Kumar, Jae Ho Lee, Seyed R. Tabaei, Soon Seng Ng, Hitomi Shirahama, Myung Hee Kim, Won-Yong Jeon, Nam-Joon Cho

المصدر: Journal of Visualized Experiments.

مصطلحات موضوعية: 0301 basic medicine, Scaffold, Materials science, General Immunology and Microbiology, General Chemical Engineering, General Neuroscience, Bioengineering, 02 engineering and technology, Colloidal crystal, 021001 nanoscience & nanotechnology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Polymerization, Tissue engineering, Cell culture, Self-healing hydrogels, Biophysics, 0210 nano-technology, Cytotoxicity, Ethylene glycol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eaaa4927c387edf66c1c39158185398
https://doi.org/10.3791/54331-v

المؤلفون: Vincent Chan, Koon Gee Neoh, Wei Ning Chen, En-Tang Kang, Tao He, Soon Seng Ng, Ying Zhang, Ning Fang

المصدر: Bio-medical materials and engineering. 24(2)

مصطلحات موضوعية: Surface Properties, Kinetics, Myocytes, Smooth Muscle, Biomedical Engineering, Acrylic Resins, Ligands, Lower critical solution temperature, Cell Line, Biomaterials, chemistry.chemical_compound, Coated Materials, Biocompatible, Hyaluronic acid, Cell Adhesion, Animals, Hyaluronic Acid, Cell adhesion, Ligand, Temperature, General Medicine, Adhesion, Elastin, Rats, chemistry, Poly(N-isopropylacrylamide), Biophysics, Adhesive, Collagen, Laminin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7180049469843301eb34353e337d24bb
https://pubmed.ncbi.nlm.nih.gov/24642971