نتائج البحث - "Son Jung Beom"

1

Academic Journal

p21-activated kinase 4 inhibition protects against liver ischemia/reperfusion injury: Role of nuclear factor erythroid 2-related factor 2 phosphorylation

المؤلفون: Mao, Yuancheng, Han, Chang Yeob, Hao, Lihua, Lee, Younho, Son, Jung Beom, Choi, Hwangeun, Lee, Mi Rin, Do Yang, Jae, Hong, Suk Kyun, Suh, Kyung-Suk, Yu, Hee Chul, Kim, Nam Doo, Bae, Eun Ju, Park, Byung-Hyun

المساهمون: Suh, Kyung-Suk

Relation: Hepatology, Vol.76 No.2, pp.345-356; https://hdl.handle.net/10371/184948; 000784450600001; 2-s2.0-85128558452; 167951

الاتاحة: https://hdl.handle.net/10371/184948
https://doi.org/10.1002/hep.32384

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2

Academic Journal

Pan-Src kinase inhibitor treatment attenuates diabetic kidney injury via inhibition of Fyn kinase-mediated endoplasmic reticulum stress

المؤلفون: Dorotea, Debra, Jiang, Songling, Pak, Eun Seon, Son, Jung Beom, Choi, Hwan Geun, Ahn, Sung-Min, Ha, Hunjoo

المساهمون: National Research Foundation of Korea, RP-Grant 2021 of Ewha Womans University

المصدر: Experimental & Molecular Medicine ; volume 54, issue 8, page 1086-1097 ; ISSN 2092-6413

الاتاحة: http://dx.doi.org/10.1038/s12276-022-00810-3
https://www.nature.com/articles/s12276-022-00810-3.pdf
https://www.nature.com/articles/s12276-022-00810-3

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3

Patent

Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase

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4

X-ray Crystal Structure-Guided Design and Optimization of 7H-Pyrrolo[2,3-d]pyrimidine-5-carbonitrile Scaffold as a Potent and Orally Active Monopolar Spindle 1 Inhibitor

المؤلفون: Seo Kyung Ah, Son Jung Beom, Ikyon Kim, Jun Goo Jee, Nam Doo Kim, Kim Hyunkyung, Haelee Kim, Eunhwa Ko, Hwan Geun Choi, Younho Lee, Ha Yeon Cho

المصدر: Journal of Medicinal Chemistry. 64:6985-6995

مصطلحات موضوعية: 0303 health sciences, Scaffold, Pyrimidine, Crystal structure, Tnbc cell, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, Orally active, chemistry, In vivo, Drug Discovery, Cancer research, Molecular Medicine, Protein kinase A, Monopolar spindle, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::efd1e225ff0d0ed781f23a424e08089d
https://doi.org/10.1021/acs.jmedchem.1c00542

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5

Patent

Thieno[3,2-d]pyrimidine derivatives having inhibitory activity on protein kinases

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6

Patent

Indazole derivatives or pharmaceutically acceptable salts thereof as protein kinase inhibitors for proliferative diseases treatment, and a pharmaceutical composition containing the same as an active ingredient

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7

KF-1607, a Novel Pan Src Kinase Inhibitor, Attenuates Obstruction-Induced Tubulointerstitial Fibrosis in Mice

المؤلفون: Gayoung Lee, Hunjoo Ha, Lee Sun Joo, Sung Min Ahn, Son Jung Beom, Seungyeon Lee, Hwan Geun Choi, Debra Dorotea

المصدر: Biomolecules & Therapeutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846dff003ac339b295eeec7e321ead57
https://pubmed.ncbi.nlm.nih.gov/32690822

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8

Patent

BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE

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9

Patent

NOVEL INDAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS PROTEIN KINASE INHIBITORS FOR PROLIFERATIVE DISEASES TREATMENT, AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT

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10

Academic Journal

Total Synthesis, Structural Revision, and Absolute Configuration of (+)-Clavosolide A

المؤلفون: Son, Jung Beom, Kim, Si Nae, Kim, Na Yeong, Lee, Duck Hyung

المصدر: Organic Letters ; volume 8, issue 15, page 3411-3411 ; ISSN 1523-7060 1523-7052

الاتاحة: http://dx.doi.org/10.1021/ol061172p
https://pubs.acs.org/doi/pdf/10.1021/ol061172p

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11

Discovery of a potent dual ALK and EGFR T790M inhibitor

المؤلفون: Pasi A. Jänne, Jaebong Jang, Kim So Young, Son Jung Beom, Ciric To, Nathanael S. Gray, Magda Bahcall, Younho Lee, Mierzhati Mushajiang, Kang Seock Yong, Hwan Geun Choi

المصدر: European Journal of Medicinal Chemistry. 136:497-510

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Antineoplastic Agents, Pharmacology, Article, Small Molecule Libraries, Structure-Activity Relationship, 03 medical and health sciences, T790M, 0302 clinical medicine, Cell Line, Tumor, hemic and lymphatic diseases, Drug Discovery, medicine, Humans, Anaplastic lymphoma kinase, Anaplastic Lymphoma Kinase, Osimertinib, Epidermal growth factor receptor, Protein Kinase Inhibitors, Cell Proliferation, EGFR inhibitors, Dose-Response Relationship, Drug, Molecular Structure, biology, Ceritinib, Chemistry, Organic Chemistry, Receptor Protein-Tyrosine Kinases, General Medicine, ErbB Receptors, ALK inhibitor, 030104 developmental biology, Cell culture, 030220 oncology & carcinogenesis, biology.protein, Drug Screening Assays, Antitumor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace9e39fdca483aec84f85feb73a8c21
https://doi.org/10.1016/j.ejmech.2017.04.079

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12

Abstract LB139: VRN10, Discovery of Potent Irreversible HER2 Kinase Inhibitors with Intracranial Activity

المؤلفون: Somi Lee, Eunhwa Ko, Nam Doo Kim, Sunghwan Kim, Hwan Geun Choi, Kim Hwan, Ji Eun Choi, Younho Lee, Chanmi Park, Jihye Yoo, Son Jung Beom, Daekwon Kim, Park Jin-Hee, Youngyi Lee

المصدر: Cancer Research. 81:LB139-LB139

مصطلحات موضوعية: MAPK/ERK pathway, Cancer Research, Chemistry, Kinase, Cancer, Lapatinib, medicine.disease, Oncology, In vivo, Neratinib, medicine, Cancer research, Signal transduction, skin and connective tissue diseases, Protein kinase B, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b365ccbefb06004be8e8ee65e5554603
https://doi.org/10.1158/1538-7445.am2021-lb139

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13

Abstract LB119: VRN08, a Selective Mps1 Kinase Inhibitor Induces Mitotic Catastrophe and Apoptosis Efficiently in Advanced Cancers Including Rb1-Deficient

المؤلفون: Yeon-Sil Kim, Nam Doo Kim, Dong-hyuk Seo, Ji-Hye Kwon, Haelee Kim, Jung Hong Ryul, Sunghwan Kim, Son Jung Beom, Daekwon Kim

المصدر: Cancer Research. 81:LB119-LB119

مصطلحات موضوعية: Cancer Research, Spindle checkpoint, Oncology, Cell division, Tumor suppressor gene, Kinase, Chemistry, Chromosome instability, Cancer research, Cell cycle, Mitotic catastrophe, Mitosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8ef3fdf2a369e5f414fc8cfbd9f771ee
https://doi.org/10.1158/1538-7445.am2021-lb119

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14

Abstract 1466: ORIC-114, a brain penetrant, orally bioavailable, irreversible inhibitor selectively targets EGFR and HER2 exon20 insertion mutants and regresses intracranial NSCLC xenograft tumors

المصدر: Cancer Research. 81:1466-1466

مصطلحات موضوعية: Cancer Research, biology, business.industry, Cell, Cancer, medicine.disease, medicine.anatomical_structure, Oncology, In vivo, medicine, Cancer research, biology.protein, Kinome, Viability assay, Epidermal growth factor receptor, business, Receptor, EGFR inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7df9d4530299f94f91c3e624cd7871c0
https://doi.org/10.1158/1538-7445.am2021-1466

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15

Abstract 2211: Discovery of orally available and potent MPS1(TTK) kinase inhibitors for anti-cancer drugs

المؤلفون: Kang Sein, Jaeyoung Ahn, Hyun Kyung Kim, Kang Juhee, Younho Lee, Son Jung Beom, Kyung-ah Seo, Ji Eun Choi, Nam Doo Kim

المصدر: Cancer Research. 79:2211-2211

مصطلحات موضوعية: Cancer Research, biology, business.industry, Kinase, Cell, Cell cycle, Spindle checkpoint, chemistry.chemical_compound, medicine.anatomical_structure, Oncology, Paclitaxel, chemistry, Cyclin-dependent kinase, Mitotic exit, Cancer research, biology.protein, Medicine, business, Mitosis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6301c5ab5725fd6fa8b96d99e0b7c0e7
https://doi.org/10.1158/1538-7445.am2019-2211

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16

Abstract 2209: Novel therapeutic agents for RET-driven cancers, which is highly potent and selective inhibitor to RET kinase

المؤلفون: Hyun Kyung Kim, Kim Hwan, Nam Doo Kim, Jo Seohyun, Ji Eun Choi, Ji-hoon Oh, Do Woomi, Son Jung Beom, Kyung-ah Seo, Li Hua, Jaeyoung Ahn

المصدر: Cancer Research. 79:2209-2209

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, Cancer Research, endocrine system diseases, Cabozantinib, Chemistry, Kinase, Medullary thyroid cancer, Vandetanib, medicine.disease, chemistry.chemical_compound, Oncology, medicine, Cancer research, Phosphorylation, Potency, Cytotoxicity, Tyrosine kinase, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e783ba4eed8d6a819d8e03c9ce8fa354
https://doi.org/10.1158/1538-7445.am2019-2209

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17

Suppression of the metastatic spread of breast cancer by DN10764 (AZD7762)-mediated inhibition of AXL signaling

المؤلفون: Hong-Yan Nan, ChuHee Lee, Hwan Geun Choi, Joon-Suk Park, Hyun-Kyoung Kim, Sukkyoon Yoon, Kim Dayea, Kim Namdoo, Cho Joong-Heui, Sun-Hwa Lee, Choong-Yong Kim, Eunhwa Ko, Son Jung Beom

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Time Factors, Apoptosis, Metastasis, 0302 clinical medicine, Cell Movement, Medicine, Urea, Tube formation, Caspase 7, Mice, Inbred BALB C, Kinase, Caspase 3, Primary tumor, 3. Good health, Tumor Burden, Oncology, 030220 oncology & carcinogenesis, Intercellular Signaling Peptides and Proteins, Female, RNA Interference, signal transduction, Research Paper, kinase inhibitor, Mice, Nude, Neovascularization, Physiologic, Antineoplastic Agents, Breast Neoplasms, Thiophenes, Adenocarcinoma, Transfection, 03 medical and health sciences, Breast cancer, breast cancer, Proto-Oncogene Proteins, Human Umbilical Vein Endothelial Cells, Animals, Humans, metastasis, Protein Kinase Inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, Cell growth, business.industry, Receptor Protein-Tyrosine Kinases, AXL, medicine.disease, Xenograft Model Antitumor Assays, Axl Receptor Tyrosine Kinase, 030104 developmental biology, A549 Cells, Immunology, Cancer research, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d9fed295190472ed04aef6f5d40e53
https://pubmed.ncbi.nlm.nih.gov/27829217

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18

Academic Journal

ChemInform Abstract: Enantioselective Total Synthesis of (‐)‐Clavosolide A and B.

المؤلفون: Son, Jung Beom, Kim, Si Nae, Kim, Na Yeong, Hwang, Min‐ho, Lee, Wonsun, Lee, Duck Hyung

المصدر: ChemInform ; volume 41, issue 31 ; ISSN 0931-7597 1522-2667

الاتاحة: http://dx.doi.org/10.1002/chin.201031208
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.201031208
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.201031208

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19

Academic Journal

An efficient and enantioselective total synthesis of naturally occurring L-783277

المؤلفون: Choi, Hwan Geun, Son, Jung Beom, Park, Dong-Sik, Ham, Young Jin, Hah, Jung-Mi, Sim, Taebo

المصدر: Tetrahedron Letters ; volume 51, issue 38, page 4942-4946 ; ISSN 0040-4039

الاتاحة: http://dx.doi.org/10.1016/j.tetlet.2010.07.122
https://api.elsevier.com/content/article/PII:S0040403910013286?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0040403910013286?httpAccept=text/plain

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20

Academic Journal

ChemInform Abstract: Enantioselective Total Synthesis of (‐)‐Clavosolide B.

المؤلفون: Son, Jung Beom, Hwang, Min‐ho, Lee, Wonsun, Lee, Duck‐Hyung

المصدر: ChemInform ; volume 39, issue 8 ; ISSN 0931-7597 1522-2667

الاتاحة: http://dx.doi.org/10.1002/chin.200808208
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.200808208
https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.200808208

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