المؤلفون: Alexander M Kloosterman, Peter Cimermancic, Somayah S Elsayed, Chao Du, Michalis Hadjithomas, Mohamed S Donia, Michael A Fischbach, Gilles P van Wezel, Marnix H Medema

المصدر: PLoS Biology, Vol 18, Iss 12, p e3001026 (2020)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

URL الوصول: https://doaj.org/article/37a2f5ceef8e46f8a72e0714fee61104

المؤلفون: Isabel Nuñez Santiago, Nataliia V. Machushynets, Marija Mladic, Doris A. van Bergeijk, Somayah S. Elsayed, Thomas Hankemeier, Gilles P. van Wezel

المصدر: Communications Chemistry, Vol 7, Iss 1, Pp 1-10 (2024)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3669

URL الوصول: https://doaj.org/article/0c87ac983fb441bc8d63c0baaabb8440

المؤلفون: Somayah S. Elsayed, Helga U. van der Heul, Xiansha Xiao, Aleksi Nuutila, Laura R. Baars, Changsheng Wu, Mikko Metsä-Ketelä, Gilles P. van Wezel

المصدر: Communications Chemistry, Vol 6, Iss 1, Pp 1-16 (2023)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3669

URL الوصول: https://doaj.org/article/552e4cdb804544a5861a5f3671f524ed

المؤلفون: Mandy B. Hulst, Le Zhang, Helga U. van der Heul, Chao Du, Somayah S. Elsayed, Arina Koroleva, Thadee Grocholski, Dennis P. A. Wander, Mikko Metsä-Ketelä, Jacques J. C. Neefjes, Gilles P. van Wezel

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)

مصطلحات موضوعية: doxorubicin, anthracyclines, anticancer, metabolic engineering, biosynthesis, Streptomyces, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2024.1363803/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/4df9c2d97b6a46d0a40d7261af1249f7

المؤلفون: Jack Jansma, Nicola U. Thome, Markus Schwalbe, Anastasia Chrysovalantou Chatziioannou, Somayah S. Elsayed, Gilles P. van Wezel, Pieter van den Abbeele, Saskia van Hemert, Sahar El Aidy

المصدر: Gut Microbes, Vol 15, Iss 1 (2023)

مصطلحات موضوعية: Probiotics, gut microbiota, small intestine, dynamic correlation-based networks, metabolites, sequencing, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

URL الوصول: https://doaj.org/article/aefc9eaf089d4395beb16aea36d020a3

المؤلفون: Nataliia V. Machushynets, Somayah S. Elsayed, Chao Du, Maxime A. Siegler, Mercedes de la Cruz, Olga Genilloud, Thomas Hankemeier, Gilles P. van Wezel

المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Medicine, Science

Relation: https://doi.org/10.1038/s41598-022-06736-0; https://doaj.org/toc/2045-2322; https://doaj.org/article/936e287858154edda7e76a3907273f6b

الاتاحة: https://doi.org/10.1038/s41598-022-06736-0
https://doaj.org/article/936e287858154edda7e76a3907273f6b

المؤلفون: Doris A. van Bergeijk, Somayah S. Elsayed, Chao Du, Isabel Nuñez Santiago, Anna M. Roseboom, Le Zhang, Victor J. Carrión, Herman P. Spaink, Gilles P. van Wezel

المصدر: Communications Chemistry, Vol 5, Iss 1, Pp 1-12 (2022)

مصطلحات موضوعية: Chemistry, QD1-999

Relation: https://doi.org/10.1038/s42004-022-00632-4; https://doaj.org/toc/2399-3669; https://doaj.org/article/38cafff306da48aa90a4c69594586c68

الاتاحة: https://doi.org/10.1038/s42004-022-00632-4
https://doaj.org/article/38cafff306da48aa90a4c69594586c68

المؤلفون: Mandy B. Hulst, Le Zhang, Helga U. van der Heul, Chao Du, Somayah S. Elsayed, Arina Koroleva, Thadee Grocholski, Dennis P. A. Wander, Mikko Metsä-Ketelä, Jacques J. C. Neefjes, Gilles P. van Wezel

مصطلحات موضوعية: Biotechnology, Biological Engineering, Genetic Engineering, Biomarkers, Biomaterials, Biomechanical Engineering, Biomedical Engineering not elsewhere classified, Synthetic Biology, Agricultural Marine Biotechnology, Bioremediation, Bioprocessing, Bioproduction and Bioproducts, Industrial Biotechnology Diagnostics (incl. Biosensors), Industrial Microbiology (incl. Biofeedstocks), Industrial Molecular Engineering of Nucleic Acids and Proteins, Industrial Biotechnology not elsewhere classified, Medical Biotechnology Diagnostics (incl. Biosensors), Medical Molecular Engineering of Nucleic Acids and Proteins, Regenerative Medicine (incl. Stem Cells and Tissue Engineering), Medical Biotechnology not elsewhere classified, doxorubicin, anthracyclines, anticancer, metabolic engineering, biosynthesis, Streptomyces

Relation: https://figshare.com/articles/dataset/DataSheet1_Metabolic_engineering_of_Streptomyces_peucetius_for_biosynthesis_of_N_N-dimethylated_anthracyclines_PDF/25305847

الاتاحة: https://doi.org/10.3389/fbioe.2024.1363803.s001
https://figshare.com/articles/dataset/DataSheet1_Metabolic_engineering_of_Streptomyces_peucetius_for_biosynthesis_of_N_N-dimethylated_anthracyclines_PDF/25305847

المؤلفون: Karol Al Ayed, Denise Zamarbide Losada, Nataliia V. Machushynets, Barbara Terlouw, Somayah S. Elsayed, Julian Schill, Vincent Trebosc, Michel Pieren, Marnix H. Medema, Gilles P. van Wezel, Nathaniel I. Martin

المصدر: ACS Infectious Diseases 9 (2023) 4
ACS Infectious Diseases, 9(4), 739-748

مصطلحات موضوعية: Infectious Diseases, relacidine, Bioinformatics, NRPS, Bioinformatica, AMR, bioinformatics, EPS, total synthesis, lipopeptides

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8b1f8dc30b226e87fcbcb3a89f3277
https://doi.org/10.1021/acsinfecdis.3c00043

المؤلفون: Jack Jansma, Nicola U. Thome, Markus Schwalbe, Anastasia Chrysovalantou Chatziioannou, Somayah S. Elsayed, Gilles P. van Wezel, Pieter van den Abbeele, Saskia van Hemert, Sahar El Aidy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ade563a261d3a11f36325f0a8d1aceb
https://doi.org/10.1101/2023.01.29.525861

المؤلفون: Doris A. van Bergeijk, Hannah E. Augustijn, Somayah S. Elsayed, Joost Willemse, Victor J. Carrión, Mia Urem, Lena V. Grigoreva, Maksim Y. Cheprasov, Semyon Grigoriev, Bas Wintermans, Andries E. Budding, Herman P. Spaink, Marnix H. Medema, Gilles P. van Wezel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::432c94bcb012bd24ecbbf14af8e41485
https://doi.org/10.1101/2022.12.22.521380

المؤلفون: Peter H. Nibbering, Somayah S. Elsayed, Wietse de Boer, Gilles P. van Wezel, Maxime A. Siegler, Thomas Hankemeier, Grégory Genta-Jouve, Víctor J. Carrión

المساهمون: Microbial Ecology (ME)

المصدر: The Journal of Organic Chemistry
Journal of organic chemistry, 85(16), 10648-10657. American Chemical Society
Journal Of Organic Chemistry (0022-3263) (Amer Chemical Soc), 2020-08, Vol. 85, N. 16, P. 10648-10657
Journal of Organic Chemistry 85 (2020) 16
Journal of Organic Chemistry, 85(16), 10648-10657. AMER CHEMICAL SOC
Journal of Organic Chemistry, 85(16), 10648-10657

مصطلحات موضوعية: Genus Streptomyces, biology, Genus Streptacidiphilus, Chemistry, Streptomycetaceae, Stereochemistry, 010405 organic chemistry, Organic Chemistry, Plan_S-Compliant_NO, Soil Biology, biology.organism_classification, PE&RC, 010402 general chemistry, 01 natural sciences, Streptomyces, Article, Anti-Bacterial Agents, 0104 chemical sciences, Polyketide, Polyketides, international, Life Science, Streptacidiphilus, Bodembiologie

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a509269b41a568abbc93d4a812790da
http://europepmc.org/articles/PMC7497648

المؤلفون: Herman P. Spaink, Chao Du, Isabel Nunez Santiago, Le Zhang, Víctor J. Carrión, Anna Roseboom, Gilles P. van Wezel, Doris A. van Bergeijk, Somayah S. Elsayed

مصطلحات موضوعية: Catechol, chemistry.chemical_compound, chemistry, Biochemistry, biology, bacteria, Metabolism, Antibiotic production, biology.organism_classification, Streptomyces, Elicitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fb9337fcd46a54ff8279d934216bfa42
https://doi.org/10.21203/rs.3.rs-715051/v1

المؤلفون: Changsheng Wu, Andrea E. Prota, Helga U. van der Heul, Chao Du, Xiansha Xiao, Weidong Liu, Mikko Metsä-Ketelä, Chun-Chi Chen, Rey-Ting Guo, Somayah S. Elsayed, Jan Pieter Abrahams, Gilles P. van Wezel

المصدر: ACS Chemical Biology, 15(9), 2529-2538
ACS Chemical Biology

مصطلحات موضوعية: 0301 basic medicine, Rossmann fold, Conformational change, Stereochemistry, Plasma protein binding, Reductase, Cleavage (embryo), Crystallography, X-Ray, 01 natural sciences, Biochemistry, Enzyme catalysis, Substrate Specificity, 03 medical and health sciences, Polyketide, Bacterial Proteins, Catalytic Domain, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, General Medicine, Articles, Streptomyces, 0104 chemical sciences, Anti-Bacterial Agents, Alcohol Oxidoreductases, 030104 developmental biology, Enzyme, Polyketides, Mutation, Biocatalysis, Mutagenesis, Site-Directed, Molecular Medicine, Oxidation-Reduction, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8fee26a0f5dd1336b75ddf16474bfb
http://hdl.handle.net/1887/3134616

المؤلفون: Peter Cimermancic, Michael A. Fischbach, Alexander M. Kloosterman, Somayah S. Elsayed, Gilles P. van Wezel, Marnix H. Medema, Michalis Hadjithomas, Mohamed S. Donia, Chao Du

المصدر: PloS Biology, 18
PLoS Biology, Vol 18, Iss 12, p e3001026 (2020)
PLoS Biology
PloS Biology 18 (2020)
PLoS Biology, 18(12), e3001026

مصطلحات موضوعية: 0301 basic medicine, Subfamily, Pathology and Laboratory Medicine, Biochemistry, 01 natural sciences, Genome, Machine Learning, Bacteriocins, Gene cluster, Medicine and Health Sciences, Amino Acids, Biology (General), Dehydration (Medicine), Fungal Pathogens, Enzyme Precursors, Organic Compounds, General Neuroscience, Methods and Resources, Genomics, Streptomyces, Chemistry, Medical Microbiology, Multigene Family, Physical Sciences, Identification (biology), Pathogens, General Agricultural and Biological Sciences, Algorithms, QH301-705.5, Bioinformatics, Gene prediction, Protein domain, Mycology, Computational biology, Biology, 010402 general chemistry, Microbiology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Signs and Symptoms, Protein Domains, Bioinformatica, Genetics, Life Science, Sulfur Containing Amino Acids, Cysteine, Gene Prediction, Microbial Pathogens, Gene, Biological Products, General Immunology and Microbiology, Organic Chemistry, Chemical Compounds, Computational Biology, Biology and Life Sciences, Proteins, Genome Analysis, 0104 chemical sciences, 030104 developmental biology, Enzymology, Clinical Medicine, EPS, Peptides, Protein Processing, Post-Translational, Ribosomes

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412e65b2c866ff42f148c76879df05d5
https://research.wur.nl/en/publications/expansion-of-ripp-biosynthetic-space-through-integration-of-pan-g

المؤلفون: Vittorio Tracanna, Lucas William Mendes, Somayah S. Elsayed, Mattias de Hollander, John van der Oost, Juan E. Pérez-Jaramillo, Marnix H. Medema, Jos M. Raaijmakers, Víctor J. Carrión, Rodrigo Mendes, Wilfred F. J. van IJcken, Joseph N. Paulson, Daniel Ruiz-Buck, Ruth Gomez-Exposito, Prarthana Mohanraju, Viviane Cordovez, Adini Q Arifah, Gilles P. van Wezel

المساهمون: Microbial Ecology (ME), Cell biology

المصدر: Science, 366(6465), 606-612. American Association for the Advancement of Science (AAAS)
Science, 366(6465), 606-+. American Association for the Advancement of Science
Science, 366(6465), 606-612
Science 366 (2019) 6465

مصطلحات موضوعية: 0106 biological sciences, Bioinformatics, Biology, Bacterial Physiological Phenomena, 01 natural sciences, Genome, Flavobacterium, Plant Roots, Microbiology, Rhizoctonia, 03 medical and health sciences, Nonribosomal peptide, Microbiologie, Gene cluster, Bioinformatica, Endophytes, Life Science, Microbiome, Peptide Synthases, Gene, Soil Microbiology, 030304 developmental biology, Disease Resistance, Plant Diseases, chemistry.chemical_classification, Genetics, 0303 health sciences, Multidisciplinary, Bacteria, Bacteroidetes, Microbiota, Chitinases, fungi, Root microbiome, food and beverages, Biodiversity, biology.organism_classification, chemistry, Metagenomics, Genes, Bacterial, international, Mutagenesis, Site-Directed, Metagenome, Beta vulgaris, EPS, Polyketide Synthases, Genome, Bacterial, 010606 plant biology & botany

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd1220c22b7d80fc6d39935f1adddbe
https://pure.knaw.nl/portal/en/publications/deefab07-97e5-482c-9346-99ae1bdf65cd

المؤلفون: Changsheng Wu, Somayah S. Elsayed, Nataliia V. Machushynets, Thomas Hankemeier, Gilles P. van Wezel

المصدر: Journal of Industrial Microbiology and Biotechnology, 46(3-4), 483-492
Journal of Industrial Microbiology and Biotechnology
Journal of Industrial Microbiology & Biotechnology

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Bioengineering, Secondary metabolite, 4(3H)-quinazolinones, Applied Microbiology and Biotechnology, Streptomyces, Actinobacteria, chemistry.chemical_compound, Biosynthesis, Drug Discovery, medicine, Glycerol, Anthranilic acid, Metabolomics, ortho-Aminobenzoates, Molecular networking, Quinazolinone, Quinazolinones, Biological Products, Natural product, Molecular Structure, biology, biology.organism_classification, Natural Products - Original Paper, chemistry, Fermentation, Carbon source, Biotechnology, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55cd463e68701f67a95507912cb2933a
https://hdl.handle.net/1887/72041

المؤلفون: Zixin Deng, Marcel Jaspars, Yi Yu, Roland Gyampoh, Meinan Lv, Hai Deng, Kwaku Kyeremeh, Mostafa E. Rateb, Somayah S. Elsayed, Sheng Huang, Jioji N. Tabudravu, Rainer Ebel

المصدر: Chemistry & Biology. 22(12):1633-1642

مصطلحات موضوعية: Stereochemistry, Prenyltransferase, Molecular Sequence Data, Clinical Biochemistry, Carbazoles, Hydroxylation, Biochemistry, chemistry.chemical_compound, Biosynthesis, Prenylation, Tandem Mass Spectrometry, neocarazostatin A formation prenylation hydroxylation Streptomyces sequence, Drug Discovery, Escherichia coli, Moiety, Bioorganic chemistry, Cloning, Molecular, Molecular Biology, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Pharmacology, Molecular Structure, Carbazole, General Medicine, Biosynthetic Pathways, Enzyme, chemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d49d1cc7918ab7ceda94849283625c

المؤلفون: Jioji N. Tabudravu, Doe Peace, Somayah S. Elsayed, Kwaku Kyeremeh, Rainer Ebel, Hai Deng, Ming Him Tong, Sheng Huang, Yi Yu, Jeanne Travert, Laurent Trembleau, Marcel Jaspars, Sharon M. Kelly

مصطلحات موضوعية: legonmycins, Stereochemistry, Multifunctional Enzymes, Catalysis, Mixed Function Oxygenases, chemistry.chemical_compound, pyrrolizidine alkaloids, Biosynthesis, Bioorganic chemistry, Soil Microbiology, chemistry.chemical_classification, Biological Products, multifunctional enzymes, non-ribosomal peptide synthetases, Indolizidine, General Medicine, General Chemistry, Monooxygenase, Streptomyces, Enzyme, chemistry, Biochemistry, Genes, Bacterial, Multigene Family, Pyrrolizidine, Heterologous expression, Carbamates, biosynthesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1464cea4b80da5da99d326f335f92d1b
https://hdl.handle.net/1887/3201962

المؤلفون: Yi Yu, Rainer Ebel, Sheng Huang, Jioji N. Tabudravu, Doe Peace, Sharon M. Kelly, Ming Him Tong, Kwaku Kyeremeh, Jeanne Travert, Laurent Trembleau, Hai Deng, Marcel Jaspars, Somayah S. Elsayed

المصدر: Angewandte Chemie. 127:13016-13016

مصطلحات موضوعية: Carbamate, chemistry.chemical_compound, Contraction (grammar), Biosynthesis, chemistry, Stereochemistry, medicine.medical_treatment, medicine, General Medicine, Monooxygenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5dac1fcc8d6fa141f3d926e8f89c83e9
https://doi.org/10.1002/ange.201506192