المؤلفون: Halama, A., Kulinski, M., Dib, S.S., Zaghlool, S.B., Siveen, K.S., Iskandarani, A., Zierer, J., Prabhu, K.S., Satheesh, N.J., Bhagwat, A.M., Uddin, S., Kastenmüller, G., Elemento, O., Gross, S.S., Suhre, K.

المصدر: Cancer Lett. 430, 133-147 (2018)

مصطلحات موضوعية: Cancer Metabolism, Glutaminolysis Inhibition, Cancer Survival Mechanisms, Beta-oxidation, Autophagy

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/29777783; info:eu-repo/semantics/altIdentifier/wos/WOS:000436912200013; info:eu-repo/semantics/altIdentifier/isbn/0304-3835; info:eu-repo/semanti; https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53550; urn:isbn:0304-3835; urn:issn:0304-3835

الاتاحة: https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53550
https://doi.org/10.1016/j.canlet.2018.05.017

المؤلفون: Siveen, K.S., Kuttan, Girija

المصدر: Immunopharmacology and Immunotoxicology ; volume 34, issue 1, page 116-125 ; ISSN 0892-3973 1532-2513

الاتاحة: http://dx.doi.org/10.3109/08923973.2011.586703
http://www.tandfonline.com/doi/pdf/10.3109/08923973.2011.586703

المؤلفون: Siveen, K.S., Kuttan, Girija

المصدر: Immunopharmacology and Immunotoxicology ; volume 33, issue 3, page 423-432 ; ISSN 0892-3973 1532-2513

الاتاحة: http://dx.doi.org/10.3109/08923973.2010.526614
http://www.tandfonline.com/doi/pdf/10.3109/08923973.2010.526614

المؤلفون: Prabhu K.S., Siveen K.S., Kuttikrishnan S., Jochebeth A., Ali T.A., Elareer N.R., Iskandarani A., Khan A.Q., Merhi M., Dermime S., El-Elimat T., Oberlies N.H., Alali F.Q., Steinhoff M., Uddin S.

مصطلحات موضوعية: AKT, Imatinib, Greensporone A, Apoptosis, Reactive oxygen species, cIAP

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1664::879cd3b7dd95ca1e7c067fee6445a88f
https://hdl.handle.net/10576/14202

المؤلفون: Shanmugam, M.K, Ahn, K.S, Lee, J.H, Kannaiyan, R, Mustafa, N, Manu, K.A, Siveen, K.S, Sethi, G, Chng, W.J, Kumar, A.P

المساهمون: PHARMACOLOGY, MEDICINE, DUKE-NUS MEDICAL SCHOOL, CANCER SCIENCE INSTITUTE OF SINGAPORE

المصدر: Unpaywall 20200831

مصطلحات موضوعية: bortezomib, caspase 3, celastrol, chemokine receptor CXCR4, gelatinase B, immunoglobulin enhancer binding protein, interleukin 6, syndecan 1, tumor necrosis factor, animal cell, animal experiment, animal model, animal tissue, antineoplastic activity, apoptosis, Article, cell invasion, cell migration, cell proliferation, controlled study, CXCR4 gene, drug effect, drug structure, enzyme activation, enzyme repression, gene product, human, human cell, human tissue, in vitro study

Relation: Shanmugam, M.K, Ahn, K.S, Lee, J.H, Kannaiyan, R, Mustafa, N, Manu, K.A, Siveen, K.S, Sethi, G, Chng, W.J, Kumar, A.P (2018). Celastrol attenuates the invasion and migration and augments the anticancer effects of bortezomib in a xenograft mouse model of multiple myeloma. Frontiers in Pharmacology 9 (MAY) : 365. ScholarBank@NUS Repository. https://doi.org/10.3389/fphar.2018.00365; https://scholarbank.nus.edu.sg/handle/10635/175386

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/175386

المؤلفون: Khan A.Q., Siveen K.S., Prabhu K.S., Kuttikrishnan S., Akhtar S., Shaar A., Raza A., Mraiche F., Dermime S., Uddin S.

مصطلحات موضوعية: HPV, Apoptosis, Head and neck squamous cell carcinoma, Skp2, Cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1664::fc7ed987c138a35857d5abb2e06605d1
https://hdl.handle.net/10576/13068

المؤلفون: Neelgundmath, M., Dinesh, K.R., Mohan, C.D., Li, F., Dai, X., Siveen, K.S., Paricharak, S., Mason, D.J., Fuchs, J.E., Sethi, G., Bender, A., Rangappa, K.S., Kotresh, O., Basappa

Relation: http://www.sciencedirect.com/science/article/pii/S0960894X14013730; lucris-id: 12731651; https://hdl.handle.net/1887/3197451

الاتاحة: https://hdl.handle.net/1887/3197451
http://www.sciencedirect.com/science/article/pii/S0960894X14013730
https://doi.org/10.1016/j.bmcl.2014.12.065

المؤلفون: Li F., Shanmugam M.K., Siveen K.S., Wang F., Ong T.H., Loo S.Y., Swamy M.M.M., Mandal S., Kumar A.P., Goh B.C., Kundu T., Ahn K.S., Wang L.Z., Hui K.M., Sethi G.

المساهمون: CANCER SCIENCE INSTITUTE OF SINGAPORE, PHARMACOLOGY, MECHANOBIOLOGY INSTITUTE, PHYSIOLOGY, PHARMACY, DUKE-NUS MEDICAL SCHOOL

المصدر: Unpaywall 20200831

مصطلحات موضوعية: antineoplastic agent, benzophenone derivative, cisplatin, cyclin D1, garcinol, immunoglobulin enhancer binding protein, Ki 67 antigen, protein bcl 2, survivin, tumor marker, unclassified drug, vasculotropin, biological marker, messenger RNA, plant extract, terpene, animal cell, animal experiment, animal model, animal tissue, apoptosis, area under the curve, Article, cancer combination chemotherapy, cancer inhibition, cancer model, capillary density, carcinoma cell, cell viability, chemosensitization

Relation: Li F., Shanmugam M.K., Siveen K.S., Wang F., Ong T.H., Loo S.Y., Swamy M.M.M., Mandal S., Kumar A.P., Goh B.C., Kundu T., Ahn K.S., Wang L.Z., Hui K.M., Sethi G. (2015). Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers. Oncotarget 6 (7) : 5147-5163. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.2881; https://scholarbank.nus.edu.sg/handle/10635/174150

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/174150

المؤلفون: Dai X., Ahn K.S., Kim C., Siveen K.S., Ong T.H., Shanmugam M.K., Li F., Shi J., ALAN PREM KUMAR, Wang L.Z., Goh B.C., Magae J., Hui K.M., Sethi G.

المساهمون: SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH

Relation: Dai X., Ahn K.S., Kim C., Siveen K.S., Ong T.H., Shanmugam M.K., Li F., Shi J., ALAN PREM KUMAR, Wang L.Z., Goh B.C., Magae J., Hui K.M., Sethi G. (2015). Non-invasive sensitive detection of KRAS and BRAF mutation in circulating tumor cells of colorectal cancer patients. Molecular Oncology 9 (4) : 850-860. ScholarBank@NUS Repository. https://doi.org/10.1016/j.molonc.2014.12.011; http://scholarbank.nus.edu.sg/handle/10635/127654; 000353735100009

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/127654

المؤلفون: Selvi, R.B, Swaminathan, A, Chatterjee, S, Shanmugam, M.K, Li, F, Ramakrishnan, G.B, Siveen, K.S, Chinnathambi, A, Emam Zayed, M, Alharbi, S.A, Basha, J, Bhat, A, Vasudevan, M, Dharmarajan, A, Sethi, G, Kundu, T.K

المساهمون: DEPT OF PHARMACOLOGY, CANCER SCIENCE INSTITUTE OF SINGAPORE

المصدر: Unpaywall 20200831

مصطلحات موضوعية: acetyl coenzyme A, E1A associated p300 protein, histone, luteolin, microRNA, microRNA 135a, microRNA 195, microRNA 215, microRNA let7C, protein p53, unclassified drug, antineoplastic agent, histone acetyltransferase PCAF, lysine, p300-CBP-associated factor, transcriptome, animal experiment, animal model, animal tissue, antineoplastic activity, Article, binding competition, cancer inhibition, cell cycle arrest, chromatin immunoprecipitation, controlled study, down regulation, drug binding site, drug efficacy, enzyme activity

Relation: Selvi, R.B, Swaminathan, A, Chatterjee, S, Shanmugam, M.K, Li, F, Ramakrishnan, G.B, Siveen, K.S, Chinnathambi, A, Emam Zayed, M, Alharbi, S.A, Basha, J, Bhat, A, Vasudevan, M, Dharmarajan, A, Sethi, G, Kundu, T.K (2015). Inhibition of p300 Lysine Acetyltransferase activity by Luteolin reduces tumor growth in head and neck squamous cell carcinoma (HNSCC) xenograft mouse model. Oncotarget 6 (41) : 43806-43818. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.6245; https://scholarbank.nus.edu.sg/handle/10635/175520

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/175520

المؤلفون: Perumal Samy, R., Manikandan, J., Pachiappan, A., Ooi, E.E., Aw, L.T., Stiles, B.G., Franco, O.L., Kandasamy, M., Mathi, K.M., Rane, G., Siveen, K.S., Arunachalam, C., Zayed, M.E., Alharbi, S.A., Kumar, A.P., Sethi, G., Lim, L.H.K., Chow, V.T.

المصدر: Current Molecular Medicine ; volume 15, issue 10, page 961-974 ; ISSN 1566-5240

الاتاحة: http://dx.doi.org/10.2174/1566524016666151123114123
http://eurekaselect.com/article/download/137187

المؤلفون: Siveen, K.S, Mustafa, N, Li, F, Kannaiyan, R, Ahn, K.S, Kumar, A.P, Chng, W.-J, Sethi, G

المساهمون: PHARMACOLOGY, MEDICINE, CANCER SCIENCE INSTITUTE OF SINGAPORE

المصدر: Unpaywall 20200831

مصطلحات موضوعية: bortezomib, caspase 3, chemokine receptor CXCR4, cyclooxygenase 2, doxorubicin, gelatinase B, immunoglobulin enhancer binding protein, interleukin 6, Ki 67 antigen, melphalan, nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase, protein bcl 2, syndecan 1, thymoquinone, transcription factor RelA, tumor necrosis factor alpha, vasculotropin, antineoplastic agent, benzoquinone derivative, boronic acid derivative, pyrazine derivative, animal experiment, animal model, animal tissue, antineoplastic activity, antiproliferative activity, apoptosis, article, Bcl 2 gene, cancer cell culture

Relation: Siveen, K.S, Mustafa, N, Li, F, Kannaiyan, R, Ahn, K.S, Kumar, A.P, Chng, W.-J, Sethi, G (2014). Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-?B regulated gene products in multiple myeloma xenograft mouse model. Oncotarget 5 (3) : 634-648. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.1596; https://scholarbank.nus.edu.sg/handle/10635/175000

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/175000

المؤلفون: Siveen K.S., Ahn K.S., Ong T.H., Shanmugam M.K., Li F., Yap W.N., Kumar A.P., Fong C.W., Tergaonkar V., Hui K.M., Sethi G.

المساهمون: PHARMACOLOGY, CANCER SCIENCE INSTITUTE OF SINGAPORE, BIOCHEMISTRY, DUKE-NUS MEDICAL SCHOOL

المصدر: Unpaywall 20200831

مصطلحات موضوعية: caspase 3, CD31 antigen, gamma tocotrienol, Ki 67 antigen, mammalian target of rapamycin, matrigel, protein kinase B, vasculotropin, vasculotropin receptor 2, alpha tocopherol, antineoplastic agent, chroman derivative, plastochromanol 8, vasculotropin A, angiogenesis, animal experiment, animal model, animal tissue, antiangiogenic activity, antineoplastic activity, article, autophosphorylation, cancer inhibition, cancer tissue, capillary sprouting, cell invasion, cell viability, cellular parameters, chorioallantois, concentration response

Relation: Siveen K.S., Ahn K.S., Ong T.H., Shanmugam M.K., Li F., Yap W.N., Kumar A.P., Fong C.W., Tergaonkar V., Hui K.M., Sethi G. (2014). ?-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model. Oncotarget 5 (7) : 1897-1911. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.1876; https://scholarbank.nus.edu.sg/handle/10635/174170

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/174170

المؤلفون: Bharathkumar, H, Paricharak, S, Dinesh, K.R, Siveen, K.S, Fuchs, J.E, Rangappa, S, Mohan, C.D, Mohandas, N, Kumar, A.P, Sethi, G, Bender, A, Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Palace Road, Bangalore, 560001, India, Rangappa, K.S

المساهمون: CANCER SCIENCE INSTITUTE OF SINGAPORE, ANATOMY, PHARMACOLOGY

المصدر: Unpaywall 20200831

مصطلحات موضوعية: Biological evaluation, In-silico, In-vitro

Relation: Bharathkumar, H, Paricharak, S, Dinesh, K.R, Siveen, K.S, Fuchs, J.E, Rangappa, S, Mohan, C.D, Mohandas, N, Kumar, A.P, Sethi, G, Bender, A, Basappa, Laboratory of Chemical Biology, Department of Chemistry, Bangalore University, Palace Road, Bangalore, 560001, India, Rangappa, K.S (2014). Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ. RSC Advances 4 (85) : 45143-45146. ScholarBank@NUS Repository. https://doi.org/10.1039/c4ra08713e; https://scholarbank.nus.edu.sg/handle/10635/176019

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/176019

المؤلفون: Manu, K.A., Shanmugam, M.K., Li, F., Chen, L., Siveen, K.S., Ahn, K.S., Kumar, A.P., Sethi, G.

المساهمون: CANCER SCIENCE INSTITUTE OF SINGAPORE, PHARMACOLOGY

المصدر: Scopus

مصطلحات موضوعية: Apoptosis, Chemoresistance, Gastric cancer, NF-κB, Simvastatin

Relation: Manu, K.A., Shanmugam, M.K., Li, F., Chen, L., Siveen, K.S., Ahn, K.S., Kumar, A.P., Sethi, G. (2014). Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products. Journal of Molecular Medicine 92 (3) : 267-276. ScholarBank@NUS Repository. https://doi.org/10.1007/s00109-013-1095-0; http://scholarbank.nus.edu.sg/handle/10635/109653; 000334268800008

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/109653

المؤلفون: Siveen, K.S., Ahn, K.S., Ong, T.H., Shanmugam, M.K., Li, F., Yap, W.N., Kumar, A.P., Fong, C.W., Tergaonkar, V., Hui, K.M., Sethi, G.

المساهمون: CANCER SCIENCE INSTITUTE OF SINGAPORE, DUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE, PHARMACOLOGY

المصدر: Scopus

مصطلحات موضوعية: AKT/mTOR, Angiogenesis, HCC, Orthotopic model, γ-tocotrienol

Relation: Siveen, K.S.,Ahn, K.S.,Ong, T.H.,Shanmugam, M.K.,Li, F.,Yap, W.N.,Kumar, A.P.,Fong, C.W.,Tergaonkar, V.,Hui, K.M.,Sethi, G. (2014). γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model. Oncotarget 5 (6) : 1897-1911. ScholarBank@NUS Repository.; http://scholarbank.nus.edu.sg/handle/10635/109741; NOT_IN_WOS

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/109741

المؤلفون: Bharathkumar, H., Paricharak, S., Dinesh, K.R., Siveen, K.S, Fuchs, J.E, Rangappa, S., Mohan, C.D., Mohandas, N., Kumar, A.P., Sethi, G., Bender, A., Basappa, ., Rangappa, K.S.

مصطلحات موضوعية: Chemistry

وصف الملف: text

Relation: http://eprints-bangaloreuniversity.in/3221/1/Synthesis,%20biological%20evaluation%20and%20in%20silico%20and%20in.pdf; Bharathkumar, H. and Paricharak, S. and Dinesh, K.R. and Siveen, K.S and Fuchs, J.E and Rangappa, S. and Mohan, C.D. and Mohandas, N. and Kumar, A.P. and Sethi, G. and Bender, A. and Basappa, . and Rangappa, K.S. (2014) Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ. RSC Advances, 4 (85). pp. 45143-45146. ISSN 20462069

الاتاحة: http://eprints-bangaloreuniversity.in/3221/
http://eprints-bangaloreuniversity.in/3221/1/Synthesis,%20biological%20evaluation%20and%20in%20silico%20and%20in.pdf
https://doi.org/10.1039/C4RA08713E

المؤلفون: Kumar Keerthy, H., Mohan, C.D., Siveen, K.S., Fuchs, J.E., Rangappa, S., Sundaram, M.S., Li, F., Girish, K.S., Sethi, G., Basappaa, ., Bender, A., Rangappa, K.S.

مصطلحات موضوعية: Chemistry

وصف الملف: text

Relation: http://eprints-bangaloreuniversity.in/3109/1/novel.pdf; Kumar Keerthy, H. and Mohan, C.D. and Siveen, K.S. and Fuchs, J.E. and Rangappa, S. and Sundaram, M.S. and Li, F. and Girish, K.S. and Sethi, G. and Basappaa, . and Bender, A. and Rangappa, K.S. (2014) Novel Synthetic Biscoumarins Target Tumor Necrosis Factor- in Hepatocellular Carcinoma in Vitro and in Vivo*. Journal of Biological Chemistry, 289 (46). pp. 31879-31890. ISSN 1083-351X

الاتاحة: http://eprints-bangaloreuniversity.in/3109/
http://eprints-bangaloreuniversity.in/3109/1/novel.pdf
https://doi.org/10.1074/jbc.M114.593855

المؤلفون: Subramaniam, A., Loo, S.Y., Rajendran, P., Manu, K.A., Perumal, E., Li, F., Shanmugam, M.K., Siveen, K.S., Park, J.-I., Ahn, K.S., Hui, K.M., Kumar, A.P., Sethi, G.

المساهمون: CANCER SCIENCE INSTITUTE OF SINGAPORE, DUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE, PHARMACOLOGY

المصدر: Scopus

مصطلحات موضوعية: Apoptosis, CHOP, DR4, DR5, Emodin, HCC, TRAIL

Relation: Subramaniam, A., Loo, S.Y., Rajendran, P., Manu, K.A., Perumal, E., Li, F., Shanmugam, M.K., Siveen, K.S., Park, J.-I., Ahn, K.S., Hui, K.M., Kumar, A.P., Sethi, G. (2013). An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins. Apoptosis 18 (10) : 1175-1187. ScholarBank@NUS Repository. https://doi.org/10.1007/s10495-013-0851-5; http://scholarbank.nus.edu.sg/handle/10635/108255; 000324490000004

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/108255

المؤلفون: Manu, K.A., Shanmugam, M.K., Ong, T.H., Subramaniam, A., Siveen, K.S., Perumal, E., Samy, R.P., Bist, P., Lim, L.H.K., Kumar, A.P., Hui, K.M., Sethi, G.

المساهمون: CANCER SCIENCE INSTITUTE OF SINGAPORE, DUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE, PHARMACOLOGY, PHYSICS

المصدر: Scopus

Relation: Manu, K.A., Shanmugam, M.K., Ong, T.H., Subramaniam, A., Siveen, K.S., Perumal, E., Samy, R.P., Bist, P., Lim, L.H.K., Kumar, A.P., Hui, K.M., Sethi, G. (2013-03-05). Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma. PLoS ONE 8 (3) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0057015; http://scholarbank.nus.edu.sg/handle/10635/52904; 000315637900012

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/52904