المؤلفون: Shuhei Tomimoto, Tatsuya Ojika, Norihito Shintani, Hitoshi Hashimoto, Ken-ichi Hamagami, Kazuya Ikeda, Masanori Nakata, Toshihiko Yada, Yusuke Sakurai, Takeshi Shimada, Yoshiko Morita, Chie Ishida, Akemichi Baba

المصدر: Journal of Pharmacological Sciences, Vol 107, Iss 1, Pp 41-48 (2008)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1347861319314537; https://doaj.org/toc/1347-8613

URL الوصول: https://doaj.org/article/3f4ce9701bc4438abd0e8dc41757167d

المؤلفون: Akemichi BABA, Hitoshi HASHIMOTO, Norihito SHINTANI, Shuhei TOMIMOTO, 富本 修平, 新谷 紀人, 橋本 均, 馬場 明道

المصدر: 日本薬理学雑誌 / Folia Pharmacologica Japonica. 2004, 123(4):261

المؤلفون: Yukihiko Sugimoto, Akemichi Baba, Soken Tsuchiya, Kazuki Nagayasu, Atsushi Kasai, Mai Koumoto, Norihito Shintani, Ryota Hashimoto, Shota Tanaka, Tadayasu Ohkubo, Shintaro Higashi, Atsushi Ichikawa, Takuya Yoshida, Hitoshi Hashimoto, Kazuya Ikeda, Ken Ichi Hamagami, Shuhei Tomimoto, Takanobu Nakazawa, Yukio Ago, Atsuko Hayata-Takano, Naoki Inoue, Kazuhiko Katagi, Yusuke Onaka

المصدر: Biochemical and Biophysical Research Communications. 461:612-617

مصطلحات موضوعية: Genetically modified mouse, medicine.medical_specialty, Biophysics, Mice, Transgenic, Type 2 diabetes, Carbohydrate metabolism, Biology, Diet, High-Fat, Biochemistry, High fat fed, Mice, Basal (phylogenetics), Insulin-Secreting Cells, Internal medicine, medicine, Animals, Obesity, Molecular Biology, Mitosis, geography, geography.geographical_feature_category, Pancreatic islets, Cell Biology, Islet, medicine.disease, Up-Regulation, Endocrinology, medicine.anatomical_structure, Diabetes Mellitus, Type 2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb74c4e3685025e3754f7aa0633817f
https://doi.org/10.1016/j.bbrc.2015.04.074

المؤلفون: Shuhei Tomimoto, Hitoshi Hashimoto, Kazuya Ikeda, Takanobu Nakazawa, Kazuki Nagayasu, Atsuko Hayata-Takano, Atsushi Kasai, Soken Tsuchiya, Yukihiko Sugimoto, Ken Ichi Hamagami, Norihito Shintani, Atsushi Ichikawa, Akemichi Baba

المصدر: Biochemistry and Biophysics Reports

مصطلحات موضوعية: Genetically modified mouse, medicine.medical_specialty, endocrine system, Pancreatic islet hyperplasia, PACAP, pituitary adenylate cyclase-activating polypeptide, Biophysics, Biology, medicine.disease_cause, PACAP, Lethal yellow agouti (KKAy) diabetic mice, Chromosome, Biochemistry, Internal medicine, Gene expression, KKAy mice, lethal yellow agouti diabetic mice, medicine, Hyperinsulinemia, Mitochondrion, Gene, GO, gene ontology, geography, Mutation, geography.geographical_feature_category, Pancreatic islets, PACAP-Tg mice, transgenic mice overexpressing PACAP in pancreatic β-cells, Islet, medicine.disease, Ribosome, Endocrinology, medicine.anatomical_structure, hormones, hormone substitutes, and hormone antagonists, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de28fb0e7a854bb69932f71c2b7ffc96
http://europepmc.org/articles/PMC5668656

المؤلفون: Takeshi Shimada, Yoshiko Morita, Norihito Shintani, Tatsuya Ojika, Masanori Nakata, Shuhei Tomimoto, Hitoshi Hashimoto, Kazuya Ikeda, Ken-ichi Hamagami, Yusuke Sakurai, Chie Ishida, Toshihiko Yada, Akemichi Baba

المصدر: Journal of Pharmacological Sciences, Vol 107, Iss 1, Pp 41-48 (2008)

مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Time Factors, Adipose Tissue, White, Adipose tissue, White adipose tissue, Biology, Fatty Acid-Binding Proteins, Eating, Islets of Langerhans, Mice, chemistry.chemical_compound, Insulin resistance, Internal medicine, Adipocyte, medicine, Animals, Homeostasis, Insulin, Glucose homeostasis, Resistin, RNA, Messenger, Triglycerides, Mice, Knockout, Pharmacology, Glucose tolerance test, medicine.diagnostic_test, lcsh:RM1-950, Body Weight, Lipid metabolism, Organ Size, Glucose Tolerance Test, medicine.disease, Dietary Fats, lcsh:Therapeutics. Pharmacology, Endocrinology, chemistry, Pituitary Adenylate Cyclase-Activating Polypeptide, Molecular Medicine, Energy Metabolism, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56431e3bec3c153b08094a7e832e5bf9
https://doi.org/10.1254/jphs.fp0072173

المؤلفون: Toshio Matsuda, Yoshiyuki Sakai, Megumi Hirose, Sayoko Suetake, Hitoshi Hashimoto, Kazumi Koga, Chihiro Kawaguchi, Yoshiko Morita, Norihito Shintani, Shuhei Tomimoto, Atsushi Kasai, Akemichi Baba

المصدر: Regulatory Peptides. 126:123-128

مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Physiology, Clinical Biochemistry, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Excitotoxicity, Glutamic Acid, Neuropeptide, Receptors, Cell Surface, medicine.disease_cause, Biochemistry, Neuroprotection, Cellular and Molecular Neuroscience, Endocrinology, Neurotrophic factors, Internal medicine, medicine, Animals, Nerve Growth Factors, RNA, Messenger, Rats, Wistar, Cells, Cultured, Cerebral Cortex, Neurons, Brain-derived neurotrophic factor, Neurotransmitter Agents, Cell Death, biology, Brain-Derived Neurotrophic Factor, Neuropeptides, Glutamate receptor, Peptide Fragments, Rats, Pituitary adenylate cyclase-activating peptide, Gene Expression Regulation, biology.protein, Pituitary Adenylate Cyclase-Activating Polypeptide, hormones, hormone substitutes, and hormone antagonists, Neurotrophin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c104b8701e336d4201fca1d511398d
https://doi.org/10.1016/j.regpep.2004.08.014

المؤلفون: Akemichi Baba, Hitoshi Hashimoto, Shuhei Tomimoto, Kazuhiro Tanaka, Norihito Shintani, Chihiro Kawaguchi

المصدر: Regulatory Peptides. 123:155-159

مصطلحات موضوعية: Male, Genetically modified mouse, Heterozygote, endocrine system, medicine.medical_specialty, Physiology, Ratón, Transgene, Clinical Biochemistry, Gene Expression, Neuropeptide, Mice, Transgenic, Biology, Weight Gain, Biochemistry, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Endocrinology, Internal medicine, medicine, Animals, Nerve Growth Factors, Neurotransmitter, Pancreas, Crosses, Genetic, Mice, Knockout, Neurotransmitter Agents, Base Sequence, Homozygote, Neuropeptides, DNA, Mice, Inbred C57BL, Pituitary adenylate cyclase-activating peptide, chemistry, Knockout mouse, Pituitary Adenylate Cyclase-Activating Polypeptide, Female, hormones, hormone substitutes, and hormone antagonists, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7111b8da2f2bca14a825a542ab067bf
https://doi.org/10.1016/j.regpep.2004.04.022

المؤلفون: Shuhei Tomimoto, Norihito Shintani, Chihiro Kawaguchi, Hitoshi Hashimoto, Akemichi Baba

المصدر: Life Sciences. 74:337-343

مصطلحات موضوعية: Genetically modified mouse, endocrine system, medicine.medical_specialty, medicine.medical_treatment, Neuropeptide, Biology, General Biochemistry, Genetics and Molecular Biology, Mice, Internal medicine, medicine, Animals, Homeostasis, Insulin, General Pharmacology, Toxicology and Pharmaceutics, Pancreas, Mice, Knockout, geography, geography.geographical_feature_category, Behavior, Animal, Neuropeptides, Brain, General Medicine, Islet, Mice, Inbred C57BL, Glucose, Phenotype, medicine.anatomical_structure, Endocrinology, Gene Targeting, Knockout mouse, Pituitary Adenylate Cyclase-Activating Polypeptide, Signal transduction, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db3b678026dd031f1d321640c0a6a42
https://doi.org/10.1016/j.lfs.2003.09.021

المؤلفون: Kazuhiro Tanaka, Kazuya Yamagata, Jun-ichi Miyazaki, Kazumi Koga, Fumi Tashiro, Ming Li, Norihito Shintani, Akemichi Baba, Jun-ichiro Miyagawa, Yuji Matsuzawa, Yuki Kawabata, Hiroyuki Aihara, Shuhei Tomimoto, Wakaba Mori, Toshio Matsuda, Takao Nammo, Yuji Fukuyama, Hitoshi Hashimoto, K. Yamamoto

المصدر: Diabetes. 52:1155-1162

مصطلحات موضوعية: Genetically modified mouse, endocrine system, medicine.medical_specialty, Time Factors, Endocrinology, Diabetes and Metabolism, Transgene, Apoptosis, Mice, Transgenic, Biology, Glucagon, Diabetes Mellitus, Experimental, Secretin, Islets of Langerhans, Mice, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Animals, Humans, Insulin, RNA, Messenger, Promoter Regions, Genetic, Glucose tolerance test, medicine.diagnostic_test, Pancreatic islets, Neuropeptides, Blotting, Northern, Streptozotocin, Kinetics, medicine.anatomical_structure, Endocrinology, Organ Specificity, Pituitary Adenylate Cyclase-Activating Polypeptide, Pancreas, hormones, hormone substitutes, and hormone antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde704cd5e374e4e413c8d1792172d52
https://doi.org/10.2337/diabetes.52.5.1155

المؤلفون: Chihiro Kawaguchi, Megumi Hirose, Kazuhiro Tanaka, Masayuki Imai, Shuhei Tomimoto, Norihito Shintani, Wakaba Mori, Hitoshi Hashimoto, Akemichi Baba

المصدر: ResearcherID

مصطلحات موضوعية: Litter (animal), endocrine system, medicine.medical_specialty, Litter Size, Physiology, Ratón, media_common.quotation_subject, Clinical Biochemistry, Neuropeptide, Ovary, Biology, Biochemistry, Mice, Sexual Behavior, Animal, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, medicine, Animals, RNA, Messenger, Mating, Maternal Behavior, media_common, Mice, Knockout, Reproductive function, Reproduction, Neuropeptides, Pituitary adenylate cyclase-activating peptide, Fertility, medicine.anatomical_structure, Vagina, Pituitary Adenylate Cyclase-Activating Polypeptide, Female, Gene Deletion, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbc2e22ad12d5b58e3c3dbd4a99615f
https://doi.org/10.1016/s0167-0115(02)00169-6

المؤلفون: Yoshiyuki Sakai, Megumi Hirose, Shuhei Tomimoto, Kazuhiro Tanaka, Akemichi Baba, Ayako Ichibori, Hitoshi Hashimoto, Norihito Shintani

المصدر: ResearcherID

مصطلحات موضوعية: Intracellular Fluid, MAPK/ERK pathway, endocrine system, medicine.medical_specialty, Thapsigargin, Physiology, Clinical Biochemistry, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Naphthalenes, Biology, PC12 Cells, p38 Mitogen-Activated Protein Kinases, Biochemistry, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Endocrinology, Internal medicine, Cyclic AMP, Tumor Cells, Cultured, medicine, Animals, Receptors, Pituitary Hormone, Phosphorylation, Protein kinase A, Protein kinase C, Phospholipase C, Neuropeptides, Calcium Channel Blockers, Cyclic AMP-Dependent Protein Kinases, Protein Kinase A Inhibitor, Rats, Cell biology, Enzyme Activation, Pituitary adenylate cyclase-activating peptide, Calphostin C, chemistry, Type C Phospholipases, Pituitary Adenylate Cyclase-Activating Polypeptide, Calcium, Mitogen-Activated Protein Kinases, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89240f63a016f32527b3698541fcddb4
https://doi.org/10.1016/s0167-0115(02)00198-2

المؤلفون: Akiko Nishino, Takashi Fujita, Shuhei Tomimoto, Kyoko Itoh, Shogo Matsuyama, Yutaka Koyama, Hitoshi Hashimoto, Nami Hagihara, Norihito Shintani, Akemichi Baba, Shigekazu Nagata, Masaru Okabe, Wakaba Mori, Toshio Matsuda, K. Yamamoto, Masahito Ikawa

المصدر: Journal of Neurochemistry. 75:1810-1817

مصطلحات موضوعية: Signal peptide, Mutant, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Fluorescent Antibody Technique, Protein Sorting Signals, Biology, Transfection, Binding, Competitive, Biochemistry, Mice, Structure-Activity Relationship, Cellular and Molecular Neuroscience, Exon, Animals, RNA, Messenger, Receptors, Pituitary Hormone, Receptor, Sequence Deletion, Cell Membrane, Homozygote, Neuropeptides, Brain, Gene targeting, Exons, Molecular biology, Mice, Mutant Strains, Pituitary adenylate cyclase-activating peptide, Phenotype, Cell culture, COS Cells, Gene Targeting, Mutagenesis, Site-Directed, Pituitary Adenylate Cyclase-Activating Polypeptide, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c2451c8b2f1c2bce216ad6a6e73345
https://doi.org/10.1046/j.1471-4159.2000.0751810.x

المؤلفون: K. Yamamoto, Ken Ichi Hamagami, Yuki Kawabata, Hitoshi Hashimoto, Jun-ichiro Miyagawa, Kazuya Yamagata, Shuhei Tomimoto, Norihito Shintani, Akemichi Baba

المصدر: The Journal of pharmacology and experimental therapeutics. 309(2)

مصطلحات موضوعية: Genetically modified mouse, Blood Glucose, Male, endocrine system, medicine.medical_specialty, Adenylate kinase, Neuropeptide, Biology, Eating, Islets of Langerhans, Mice, Internal medicine, Hyperinsulinism, Genetic model, medicine, Hyperinsulinemia, Animals, Insulin, Triglycerides, Pharmacology, geography, Glucose tolerance test, geography.geographical_feature_category, Hyperplasia, medicine.diagnostic_test, Body Weight, Neuropeptides, Glucose Tolerance Test, Islet, medicine.disease, Mice, Inbred C57BL, Endocrinology, Molecular Medicine, Pituitary Adenylate Cyclase-Activating Polypeptide, Female, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccac6f3e29b5d9a91036cdbf15af61a
https://pubmed.ncbi.nlm.nih.gov/14742740

المؤلفون: Wakaba Mori, Toshio Matsuda, Kazumi Koga, Masaki Sakaue, Megumi Hirose, Akiyoshi Kunugi, Akemichi Baba, K. Yamamoto, Kazuhiro Tanaka, Hitoshi Niwa, Sayoko Suetake, Hitoshi Hashimoto, Jun-ichi Miyazaki, Fumi Tashiro, Shuhei Tomimoto, Norihito Shintani

المصدر: ResearcherID

مصطلحات موضوعية: Elevated plus maze, medicine.medical_specialty, endocrine system, Serotonin, Adenylate kinase, Neuropeptide, Striatum, Biology, Open field, Mice, Internal medicine, medicine, Animals, ADCYAP1R1, DNA Primers, Mice, Knockout, Catalepsy, Multidisciplinary, Base Sequence, Neuropeptides, Brain, Hydroxyindoleacetic Acid, Biological Sciences, Cortex (botany), Endocrinology, Haloperidol, Pituitary Adenylate Cyclase-Activating Polypeptide, hormones, hormone substitutes, and hormone antagonists, Psychomotor Performance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76df0e9849176506eae7a1b7419553ee
https://pubmed.ncbi.nlm.nih.gov/11687615

المؤلفون: Shuhei Tomimoto, Megumi Hirose, Yoshiyuki Sakai, Ayako Ichibori, Akemichi Baba, Norihito Shintani, Kazuhiro Tanaka, Hitoshi Hashimoto

المصدر: ResearcherID

مصطلحات موضوعية: MAPK/ERK pathway, endocrine system, Neurite, Pyridines, p38 mitogen-activated protein kinases, Mrna expression, Biophysics, Gene Expression, Biochemistry, PC12 Cells, p38 Mitogen-Activated Protein Kinases, Gene expression, Nerve Growth Factor, Neurites, Animals, RNA, Messenger, Enzyme Inhibitors, Molecular Biology, Flavonoids, Dose-Response Relationship, Drug, Chemistry, Neuropeptides, Imidazoles, Drug Synergism, Cell Biology, PACAP Receptors, Molecular biology, Rats, Mrna level, Pituitary Adenylate Cyclase-Activating Polypeptide, Signal transduction, Mitogen-Activated Protein Kinases, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ef1ddb2793f2a501438282e99f0011
https://pubmed.ncbi.nlm.nih.gov/11453643

المؤلفون: Shuhei Tomimoto, Nami Hagihara, Norihito Shintani, Toshio Matsuda, Yutaka Koyama, K. Yamamoto, Hitoshi Hashimoto, Wakaba Mori, Kazumi Koga, Akemichi Baba

المصدر: ResearcherID

مصطلحات موضوعية: endocrine system, Adenylate kinase, Gene Expression, Biology, Biochemistry, PC12 Cells, Protein kinase C signaling, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Nerve Growth Factor, Animals, Enzyme Inhibitors, Protein kinase A, Protein kinase C, Forskolin, Reverse Transcriptase Polymerase Chain Reaction, Colforsin, Neuropeptides, Drug Synergism, Blotting, Northern, Molecular biology, Rats, Pituitary adenylate cyclase-activating peptide, Nerve growth factor, chemistry, Pituitary Adenylate Cyclase-Activating Polypeptide, Tetradecanoylphorbol Acetate, Signal transduction, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169d2e0a4cffdf2755e8759794368bdb
https://pubmed.ncbi.nlm.nih.gov/10646500

المؤلفون: Hitoshi Hashimoto, Kazumi Koga, Norihito Shintani, Toshio Matsuda, Shuhei Tomimoto, Nami Hagihara, K. Yamamoto, Akemichi Baba, Akiyoshi Kunugi

المصدر: Japanese Journal of Pharmacology. 82:105

مصطلحات موضوعية: Pharmacology, Expression (architecture), Biology, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3d6b8f0233b10157bee752dc825b1159
https://doi.org/10.1016/s0021-5198(19)47886-4

المؤلفون: Toshio Matsuda, K. Yamamoto, Wakaba Mori, Hitoshi Hashimoto, Jun-ichi Miyazaki, Akemichi Baba, Shuhei Tomimoto, Kazumi Koga

المصدر: Japanese Journal of Pharmacology. 82:154

مصطلحات موضوعية: Pharmacology, Genetically modified mouse, medicine.medical_specialty, medicine.anatomical_structure, Endocrinology, Internal medicine, medicine, Biology, Pancreas

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::896dbe55b96bd5d690764052a480ad70
https://doi.org/10.1016/s0021-5198(19)48079-7

المؤلفون: Shuhei, Tomimoto, Hitoshi, Hashimoto, Norihito, Shintani, Kyohei, Yamamoto, Yuki, Kawabata, Ken-Ichi, Hamagami, Kazuya, Yamagata, Jun-Ichiro, Miyagawa, Akemichi, Baba

المصدر: The Journal of Pharmacology and Experimental Therapeutics; May 2004, Vol. 309 Issue: 2 p796-803, 8p

المؤلفون: Akiyoshi Kunugi, Toshio Matsuda, Shuhei Tomimoto, Wakaba Mori, Norihito Shintani, Yutaka Koyama, K. Yamamoto, Akemichi Baba, Hitoshi Hashimoto

المصدر: Biochimica et Biophysica Acta (BBA) - Biomembranes. (1-2):195-202

مصطلحات موضوعية: Agonist, Cytoplasm, Glycosylation, medicine.drug_class, Hemagglutinin epitope, Immunoblotting, Molecular Sequence Data, Cell surface expression, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Biophysics, CHO Cells, Desensitization, Transfection, Biochemistry, Epitope, Mice, chemistry.chemical_compound, Cell surface receptor, Cricetinae, medicine, Animals, Amino Acid Sequence, Receptors, Pituitary Hormone, Receptor, PACAP receptor, Base Sequence, Chemistry, Cell Membrane, Cell Biology, Tunicamycin, Flow Cytometry, Molecular biology, Hemagglutinins, Desensitization, Immunologic, COS Cells, Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I, Internalization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a5ffce2697ab264a82d953c0fd22a5