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1
المؤلفون: Disha Awasthy, Shubhada Barde, Meenakshy Venkatesh Mallya, Chandan Narayan, Vijayashree Achar
المصدر: SLAS Technology. 21:423-431
مصطلحات موضوعية: Chromatography, Dimethyl sulfoxide, Precipitation (chemistry), Cytological Techniques, Epithelial Cells, Toxicology, 01 natural sciences, Hazardous Substances, Cell Line, 0104 chemical sciences, Computer Science Applications, Dilution, Handling system, Inhibitory Concentration 50, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Medical Laboratory Technology, chemistry.chemical_compound, 0302 clinical medicine, Solubility, chemistry, 030220 oncology & carcinogenesis, Chemical Precipitation, Humans, Cytotoxicity
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2
المؤلفون: P. Raphael, C. N. Gayathri, Sunita Maria Desousa, Suresh Solapure, Kaveri Das, Shubhada Barde, B. Chandrakala
المصدر: SLAS Discovery. 10:149-156
مصطلحات موضوعية: 0301 basic medicine, Transferases (Other Substituted Phosphate Groups), Peptidoglycan, medicine.disease_cause, 01 natural sciences, Biochemistry, Uridine Diphosphate, Substrate Specificity, Analytical Chemistry, 03 medical and health sciences, Bacterial Proteins, Transferases, medicine, Escherichia coli, chemistry.chemical_classification, Chromatography, Chemistry, Monosaccharides, Substrate (chemistry), In vitro, Wheat germ agglutinin, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Paper chromatography, 030104 developmental biology, Scintillation proximity assay, Enzyme, Muramic Acids, Scintillation Counting, Molecular Medicine, Specific activity, Propionates, Peptides, Oligopeptides, Biotechnology
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3
المؤلفون: David Waterson, Stefan Kavanagh, V. Balasubramanian, Vijender Panduga, Francisco-Javier Gamo, María Santos Martínez, Shahul Hameed P, Vinayak Hosagrahara, María Belén Jiménez-Díaz, Shubhada Barde, Kakoli Mukherjee, Sandra Duffy, Santiago Ferrer, Vikas Patil, Balachandra Bandodkar, Ramachandran Sreekanth A, K.R. Prabhakar, Suresh Rudrapatna, Praveena Manjrekar, Iñigo Angulo-Barturen, Pravin Iyer, Vasan K. Sambandamurthy, Nikhil Rautela, Pamela Magistrado, Dyann F. Wirth, Sowmya Bharath, Chandan Narayan, Sapna Morayya, Murugan Chinnapattu, Pavithra Viswanath, Anandkumar Raichurkar, Krishna Koushik, Jitender Reddy, Vicky M. Avery, Achyut Sinha, Amanda K. Lukens, Disha Awasthy, Shridhar Narayanan, Laura M. Sanz, Gajanan Shanbag, Sandesh Jatheendranath, Abhishek Srivastava, Ramanatha Saralaya
المصدر: Journal of medicinal chemistry. 57(13)
مصطلحات موضوعية: Cell Survival, Plasmodium falciparum, Biological Availability, Pharmacology, Small Molecule Libraries, Antimalarials, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Pharmacokinetics, Chloroquine, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Antimalarial Agent, Malaria, Falciparum, biology, Chemistry, medicine.disease, biology.organism_classification, Bioavailability, High-Throughput Screening Assays, Mechanism of action, Molecular Medicine, Benzimidazoles, medicine.symptom, Malaria, medicine.drug
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4
المؤلفون: Sunita M. de Sousa, C. N. Naveen Kumar, Anandkumar Raichurkar, Kale Manoj Ganpat, Krishna Koushik, M. R. Manjunatha, David Waterson, Vasan K. Sambandamurthy, Vikas Shinde, K. N. Mahesh Kumar, Jitendar Reddy, Julie A. Tucker, Prashanti Madhavapeddi, Derek Ogg, Sandeep R. Ghorpade, Shubhada Barde, Halesha D. Basavarajappa, Shahul Hameed P, Samit Ganguly, V. K. Ramya, Lalit kumar Jena, Vijender Panduga, Vijaykamal Ahuja, Prakash Vachaspati, David C. McKinney, Jayashree Giridhar, Anirban Ghosh, Sheshagiri Gaonkar, Supreeth Guptha, P. Ann Boriack-Sjodin, Suresh Rudrapatna, Sreevalli Sharma, Usha Kranthi, Vaishali Humnabadkar
المصدر: Journal of medicinal chemistry. 56(21)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Pyridines, Antitubercular Agents, DNA gyrase, Mycobacterium tuberculosis, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Drug Discovery, Ribose, Structure–activity relationship, Animals, Topoisomerase II Inhibitors, Tuberculosis, Urea, Homology modeling, IC50, Mice, Inbred BALB C, biology, Dose-Response Relationship, Drug, Molecular Structure, biochemical phenomena, metabolism, and nutrition, biology.organism_classification, In vitro, Disease Models, Animal, chemistry, Biochemistry, DNA Gyrase, Molecular Medicine, Pharmacophore
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5
المؤلفون: Shubhada Barde, Jyothi S. Prabhu, Anita Borges, K. Payal, C. Deepak, Veena Rajan, P. Jagannath, Vijay Pandey, T.S. Sridhar
المصدر: International journal of colorectal disease. 22(7)
مصطلحات موضوعية: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, DNA Repair, Colorectal cancer, India, Gastroenterology, Polymerase Chain Reaction, Internal medicine, medicine, Biomarkers, Tumor, Humans, Genetic Predisposition to Disease, neoplasms, Adaptor Proteins, Signal Transducing, Aged, Neoplasm Staging, Aged, 80 and over, business.industry, Incidence (epidemiology), Incidence, nutritional and metabolic diseases, Microsatellite instability, Nuclear Proteins, Anatomical pathology, DNA, Neoplasm, Hepatology, Middle Aged, medicine.disease, Prognosis, Immunohistochemistry, digestive system diseases, Gene Expression Regulation, Neoplastic, MutS Homolog 2 Protein, Cohort, Microsatellite, Electrophoresis, Polyacrylamide Gel, Female, Microsatellite Instability, business, Colorectal Neoplasms, MutL Protein Homolog 1
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6
المؤلفون: M. N. Harish, Shubhada Barde, Umender Sharma, Suresh Solapure, Peter J. Alcock, Jyothi Bhat, Rajendra Rane, Sarah Lamb, Raman K. Roy, Dhiman Sarkar, Steve Peters, Darren Plant
المصدر: Journal of biomolecular screening. 11(8)
مصطلحات موضوعية: 0301 basic medicine, High-throughput screening, Drug Evaluation, Preclinical, Sigma Factor, Uridine Triphosphate, medicine.disease_cause, 01 natural sciences, Biochemistry, Analytical Chemistry, Mycobacterium tuberculosis, 03 medical and health sciences, chemistry.chemical_compound, RNA polymerase, medicine, Nucleotide, Escherichia coli, Fluorescent Dyes, chemistry.chemical_classification, Mycobacterium bovis, biology, Molecular Structure, Mycobacterium smegmatis, RNA, DNA-Directed RNA Polymerases, biology.organism_classification, Molecular biology, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, chemistry, Microscopy, Fluorescence, Molecular Medicine, Biotechnology