المؤلفون: Aline Mello, Ming-Fo Hsu, Shinichiro Koike, Bryan Chu, Jeff Cheng, Jun Yang, Christophe Morisseau, Natalie J. Torok, Bruce D. Hammock, Fawaz G. Haj

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 815-830 (2021)

مصطلحات موضوعية: Soluble Epoxide Hydrolase, Alcohol-Associated Liver Disease, Hepatocyte, Injury, Steatosis, Inflammation, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X20301624; https://doaj.org/toc/2352-345X

URL الوصول: https://doaj.org/article/010aa7f991b54df68a730bdad2aaaead

المؤلفون: Fumiaki YOSHIZAWA, Kodwo Amuzuah OBENG, Shinichiro KOIKE, Shinji MOCHIZUKI, Yuka TOYOSHIMA, Yusuke SATO

المصدر: Journal of Nutritional Science and Vitaminology. 2022, 68(4):312

المؤلفون: Ming-Fo Hsu, Shinichiro Koike, Aline Mello, Laura E. Nagy, Fawaz G. Haj

المصدر: Redox Biology, Vol 36, Iss , Pp 101658- (2020)

مصطلحات موضوعية: Alcoholic liver disease, Hepatocyte, Protein-tyrosine phosphatase 1B, Oxidative stress, Inflammation, Steatosis, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231720308636; https://doaj.org/toc/2213-2317

URL الوصول: https://doaj.org/article/37edabe68a404a0db9c5c82568bfa310

المؤلفون: Ming-Fo Hsu, Shinichiro Koike, Chang-Shan Chen, Sonia M. Najjar, Tzu-Ching Meng, Fawaz G. Haj

المصدر: Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116590- (2024)

مصطلحات موضوعية: Alcohol-associated liver disease, Intestine permeability, Tight junction, Shp2 pharmacological inhibition, Stress signaling, ERK signaling, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S0753332224004748; https://doaj.org/toc/0753-3322; https://doaj.org/article/7b38d6406b504e55b22e233feeb4e9be

الاتاحة: https://doi.org/10.1016/j.biopha.2024.116590
https://doaj.org/article/7b38d6406b504e55b22e233feeb4e9be

المؤلفون: Shinichiro Koike, Yukihito Kabuyama, Kodwo Amuzuah Obeng, Kunio Sugahara, Yusuke Sato, Fumiaki Yoshizawa

المصدر: Nutrients; Volume 12; Issue 9; Pages: 2665

مصطلحات موضوعية: tryptophan, protein synthesis, omics, liver, rat

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Micronutrients and Human Health; https://dx.doi.org/10.3390/nu12092665

الاتاحة: https://doi.org/10.3390/nu12092665

المؤلفون: Kodwo Amuzuah OBENG, Shinji MOCHIZUKI, Shinichiro KOIKE, Yuka TOYOSHIMA, Yusuke SATO, Fumiaki YOSHIZAWA

المصدر: Journal of nutritional science and vitaminology. 68(4)

مصطلحات موضوعية: Nutrition and Dietetics, TOR Serine-Threonine Kinases, Intracellular Signaling Peptides and Proteins, Tryptophan, Medicine (miscellaneous), Muscle Proteins, Phosphoproteins, Rats, Liver, Leucine, Protein Biosynthesis, Animals, Phosphorylation, Carrier Proteins, Muscle, Skeletal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8c9273b0dc023d4b723cd76ab5e4bf
https://pubmed.ncbi.nlm.nih.gov/36047103

المؤلفون: Jessica L Huang, Sharon Lee, Mohammad S Pourhosseinzadeh, Niels Krämer, Jaresley V Guillen, Naomi H Cinque, Paola A Aniceto, Shinichiro Koike, Mark O Huising

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0cf52a641d13a486344129956527e72a
https://doi.org/10.1101/2022.06.29.496132

المؤلفون: Bruce D. Hammock, A. F. S. Mello, Natalie J. Török, Fawaz G. Haj, Jun Yang, Ming-Fo Hsu, Bryan Chu, Christophe Morisseau, Jeff Cheng, Shinichiro Koike

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 815-830 (2021)
Cellular and molecular gastroenterology and hepatology, vol 11, iss 3
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: Steatosis, Soluble Epoxide Hydrolase, Injury, Pharmacology, Alcohol-Associated Liver Disease, Transgenic, Alcohol Use and Health, Substance Misuse, Mice, 0302 clinical medicine, Hepatocyte, Aetiology, Original Research, chemistry.chemical_classification, Epoxide Hydrolases, EpETE, epoxyeicosatetraenoic acid, LC, liquid chromatography, Liver Diseases, Liver Disease, Gastroenterology, EpDPE, epoxydocosapentaenoic acid, Alcoholic, DiHDPE, dihydroxydocosapentaenoic acid, EpODE, epoxyoctadecadienoic acid, cardiovascular system, CYP, cytochrome P450, 030211 gastroenterology & hepatology, Epoxide hydrolase 2, PPARγ, peroxisome proliferator-activated receptor-γ, SOD-1, superoxide dismutase-1, eIF2α, eukaryotic initiation factor 2α, ADH, alcohol dehydrogenase, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, Liver Diseases, Alcoholic, EpFA, epoxy fatty acid, IRE1α, inositol-requiring enzyme-1α, MS, mass spectroscopy, Ethanol, Animal, medicine.disease, sEH, soluble epoxide hydrolase, 030104 developmental biology, ALDH, aldehyde dehydrogenase, chemistry, EpETrE, epoxyeicosatrienoic acid, Drug Evaluation, Digestive Diseases, 0301 basic medicine, TNFα, tumor necrosis factor-α, NOX, nicotinamide adenine dinucleotide phosphate oxidase, Drug Evaluation, Preclinical, DMSO, dimethyl sulfoxide, medicine.disease_cause, Oral and gastrointestinal, Liver disease, Piperidines, Pharmacologic Inhibition, 2.1 Biological and endogenous factors, IL1β, interleukin 1β, eNOS, endothelial nitric oxide synthase, Preclinical, mRNA, messenger RNA, Alcoholism, medicine.anatomical_structure, Liver, Female, medicine.symptom, Chronic Liver Disease and Cirrhosis, NF-κB, nuclear factor-κB, Inflammation, Mice, Transgenic, Stress, ER, endoplasmic reticulum, ROS, reactive oxygen species, ALT, alanine aminotransferase, HETE, hydroxyeicosatetraenoic acid, ALD, alcohol-associated liver disease, medicine, Animals, lcsh:RC799-869, Nutrition, EETs, epoxyeicosatrienoic acids, TPPU, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl)urea, Hepatology, business.industry, PERK, protein kinase R-like ER kinase, Phenylurea Compounds, Lipid signaling, Disease Models, Animal, Enzyme, Good Health and Well Being, Gene Expression Regulation, Disease Models, lcsh:Diseases of the digestive system. Gastroenterology, business, Oxidative stress

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a37aec2ab2970ef64d585a65ffea8d3
http://www.sciencedirect.com/science/article/pii/S2352345X20301624

المؤلفون: Jogen Atone, Karen Wagner, Shinichiro Koike, Jun Yang, Sung Hee Hwang, Bruce D. Hammock

المصدر: Environmental Toxicology and Pharmacology. 98:104070

مصطلحات موضوعية: Pharmacology, Health, Toxicology and Mutagenesis, General Medicine, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8a0f4023b2e2130d60560b9a623880cc
https://doi.org/10.1016/j.etap.2023.104070

المؤلفون: Yanqing Xu, Fawaz Haj, Shinichiro Koike, Payam Vahmani

المصدر: Journal of Animal Science. 100:232-233

مصطلحات موضوعية: Genetics, Animal Science and Zoology, General Medicine, Food Science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ee8ba38d524dfb48fc0b10bf56b3dc05
https://doi.org/10.1093/jas/skac247.421

المؤلفون: Bryan Chu, Fawaz G. Haj, Ming-Fo Hsu, Peter J. Havel, Mark O. Huising, Christophe Morisseau, Bruce D. Hammock, Shinichiro Koike, Ahmed Bettaieb, Naoki Matsumoto

المصدر: Free Radic Biol Med

مصطلحات موضوعية: 0301 basic medicine, beta-Cell dysfunction, Type 2 diabetes, Medical Biochemistry and Metabolomics, medicine.disease_cause, Inbred C57BL, Biochemistry, Mice, 0302 clinical medicine, Glucose homeostasis, Pharmacological inhibition, 2.1 Biological and endogenous factors, Aetiology, Epoxide Hydrolases, Chemistry, Diabetes, β-Cell dysfunction, cardiovascular system, Dedifferentiation, Type 2, Epoxide hydrolase 2, medicine.medical_specialty, Biochemistry & Molecular Biology, Diet, High-Fat, Article, 03 medical and health sciences, Medicinal and Biomolecular Chemistry, Downregulation and upregulation, In vivo, Physiology (medical), Diabetes mellitus, Internal medicine, medicine, Diabetes Mellitus, Genetics, Animals, Humans, Pancreas, Metabolic and endocrine, Nutrition, medicine.disease, Diet, Mice, Inbred C57BL, High-Fat, 030104 developmental biology, Endocrinology, Soluble epoxide hydrolase, Diabetes Mellitus, Type 2, Oxidative stress, Hyperglycemia, Biochemistry and Cell Biology, Epoxyeicosatrienoic acids, 030217 neurology & neurosurgery, Ex vivo

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3daea74f9ae1f66e04517256832dd1
https://escholarship.org/uc/item/03b8h68k

المؤلفون: Yoshihiro Ito, Miguel Calvo-Rubio, Shinichiro Koike, Ahmed Bettaieb, A. F. S. Mello, José M. Villalba, Ming-Fo Hsu, Fawaz G. Haj

المصدر: Metabolism. 76:56-69

مصطلحات موضوعية: 0301 basic medicine, Kidney Disease, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Diabetic nephropathy, Kidney, Podocyte, Mice, 0302 clinical medicine, Endocrinology, 2.1 Biological and endogenous factors, Renal injury, Diabetic Nephropathies, Aetiology, Non-Receptor Type 1, Mice, Knockout, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Gene knockdown, Protein tyrosine phosphatase 1B, biology, Podocytes, Diabetes, medicine.anatomical_structure, 030220 oncology & carcinogenesis, medicine.symptom, hormones, hormone substitutes, and hormone antagonists, Signal Transduction, medicine.drug, medicine.medical_specialty, Knockout, Clinical Sciences, Renal and urogenital, Inflammation, Diet, High-Fat, Autoimmune Disease, Article, Diabetes Mellitus, Experimental, Experimental, Endocrinology & Metabolism, 03 medical and health sciences, Internal medicine, Diabetes Mellitus, medicine, Animals, Metabolic and endocrine, business.industry, Autophagy, nutritional and metabolic diseases, medicine.disease, Streptozotocin, Diet, High-Fat, Insulin receptor, 030104 developmental biology, Hyperglycemia, biology.protein, Protein Tyrosine Phosphatase, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54ddb035d6f6dd95308c1c39b023b33
https://doi.org/10.1016/j.metabol.2017.07.009

المؤلفون: Stephen M Griffey, Santana Bachaalany, Juan Sastre, Samah Chahed, Fawaz G. Haj, Shinichiro Koike, Ahmed Bettaieb

المصدر: The American journal of pathology, vol 186, iss 8

مصطلحات موضوعية: Male, 0301 basic medicine, Wistar, Systemic inflammation, Medical and Health Sciences, Oral and gastrointestinal, Mice, Pathology, 2.1 Biological and endogenous factors, Aetiology, Non-Receptor Type 1, Cancer, Mice, Knockout, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Pancreatitis, Acute Necrotizing, Reverse Transcriptase Polymerase Chain Reaction, Regular Article, medicine.anatomical_structure, Acute Necrotizing, Gastrointestinal disorder, Acute pancreatitis, Tumor necrosis factor alpha, medicine.symptom, Pancreas, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, Knockout, Inflammation, Pathology and Forensic Medicine, Proinflammatory cytokine, Pancreatic Cancer, 03 medical and health sciences, Rare Diseases, Internal medicine, medicine, Animals, Rats, Wistar, Animal, business.industry, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Endocrinology, Pancreatitis, Disease Models, Protein Tyrosine Phosphatase, Digestive Diseases, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d211cd6c75e516f944179e5cbc694657
https://doi.org/10.1016/j.ajpath.2016.04.012

المؤلفون: George R. Marcotte, Marissa Z. McMackin, Keith Baar, Gino A Cortopassi, Fawaz G. Haj, Alexey Tomilov, Stephen M Griffey, Zeyu Zhou, Shinichiro Koike, Jon J. Ramsey, Kyoungmi Kim, Kevork Hagopian, Jose Alberto Lopez-Dominguez, Marita A. Wallace, Dianna Tran, Denise M. Imai, Gabriella Perez, Megan N. Roberts, Trina A. Knotts, Elena Gutiérrez-Casado

المصدر: Cell metabolism, vol 26, iss 3

مصطلحات موضوعية: 0301 basic medicine, Male, Aging, Ketogenic, ketones, Physiology, medicine.medical_treatment, healthspan, Medical Biochemistry and Metabolomics, Inbred C57BL, memory, Diet, Carbohydrate-Restricted, Mice, low-carbohydrate diet, 0302 clinical medicine, Glycolysis, media_common, Physiological function, Longevity, Acetylation, Adaptation, Physiological, Organ Specificity, Health, ketogenic diet, Ketone bodies, Zero Hunger, Diet, Ketogenic, lifespan, Signal Transduction, medicine.medical_specialty, beta-hydroxybutyrate, media_common.quotation_subject, Physiological, 1.1 Normal biological development and functioning, Calorie restriction, Biology, Mechanistic Target of Rapamycin Complex 1, Article, 03 medical and health sciences, Endocrinology & Metabolism, Underpinning research, Internal medicine, Complementary and Integrative Health, medicine, Animals, Adaptation, Molecular Biology, Nutrition, Carbohydrate-Restricted, Cell Biology, medicine.disease, Diet, Mice, Inbred C57BL, Malnutrition, 030104 developmental biology, Endocrinology, ketone bodies, Protein Acetylation, Biochemistry and Cell Biology, 030217 neurology & neurosurgery, Ketogenic diet

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6d485307440c6c51242b0d4ad22d46
https://escholarship.org/uc/item/17s0x9k2

المؤلفون: Bruce D. Hammock, Ming-Fo Hsu, José M. Villalba, Fawaz G. Haj, Bora Inceoglu, Darryl C. Zeldin, Yoshihiro Ito, Miguel Calvo-Rubio, Artiom Gruzdev, Shinichiro Koike, Santana Bachaalany, Ahmed Bettaieb, John D. Imig, Kin Sing Stephen Lee, Samah Chahed

المصدر: Biochimica et biophysica acta. General subjects, vol 1861, iss 11 Pt A

مصطلحات موضوعية: 0301 basic medicine, podocyte, Kidney Disease, Apoptosis, Diabetic nephropathy, soluble epoxide hydrolase, 030204 cardiovascular system & hematology, urologic and male genital diseases, Kidney, Biochemistry, Podocyte, Pathogenesis, Mice, 0302 clinical medicine, 2.1 Biological and endogenous factors, Diabetic Nephropathies, Aetiology, Enzyme Inhibitors, Epoxide Hydrolases, Podocytes, Diabetes, Pharmacology and Pharmaceutical Sciences, Endoplasmic Reticulum Stress, medicine.anatomical_structure, Knockout mouse, cardiovascular system, Epoxide hydrolase 2, autophagy, Biochemistry & Molecular Biology, medicine.medical_specialty, Renal and urogenital, Biophysics, Renal function, Biology, Article, Diabetes Mellitus, Experimental, Experimental, 03 medical and health sciences, Internal medicine, Diabetes Mellitus, medicine, Autophagy, Animals, Humans, Molecular Biology, Nutrition, medicine.disease, 030104 developmental biology, Endocrinology, Hyperglycemia, Biochemistry and Cell Biology, knockout mice

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5567895d5c2f5b22bf30777f2cb80e
https://europepmc.org/articles/PMC5873293/

المؤلفون: Huma Fatima, Bruce D. Hammock, Peter J. Havel, Artiom Gruzdev, Santana Bachaalany, Shinichiro Koike, Samah Chahed, Yi Zhao, Ahmed Bettaieb, Nader Hashoush, Fawaz G. Haj, James L. Graham, Darryl C. Zeldin

المصدر: The FEBS journal, vol 284, iss 13
Bettaieb, Ahmed; Koike, Shinichiro; Chahed, Samah; Zhao, Yi; Bachaalany, Santana; Hashoush, Nader; et al.(2017). Podocyte-specific soluble epoxide hydrolase deficiency in mice attenuates acute kidney injury.. The FEBS journal, 284(13), 1970-1986. doi: 10.1111/febs.14100. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/53f09103

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, podocyte, Kidney Disease, 030204 cardiovascular system & hematology, soluble epoxide hydrolase, Medical Biochemistry and Metabolomics, Kidney, Inbred C57BL, Biochemistry, Transgenic, Podocyte, Blood Urea Nitrogen, Pathogenesis, Mice, 0302 clinical medicine, Piperidines, 2.1 Biological and endogenous factors, Aetiology, Epoxide hydrolase, Cells, Cultured, Mice, Knockout, Epoxide Hydrolases, Microscopy, Cultured, Chemistry, Reverse Transcriptase Polymerase Chain Reaction, Podocytes, Acute kidney injury, Acute Kidney Injury, Proteinuria, medicine.anatomical_structure, Knockout mouse, cardiovascular system, Cytokines, Renal and Urogenital, Tumor necrosis factor alpha, Signal Transduction, Epoxide hydrolase 2, medicine.medical_specialty, Biochemistry & Molecular Biology, Cells, Knockout, 1.1 Normal biological development and functioning, Immunoblotting, Mice, Transgenic, Fluorescence, Article, Proinflammatory cytokine, 03 medical and health sciences, Medicinal and Biomolecular Chemistry, Underpinning research, Internal medicine, medicine, Animals, Molecular Biology, Phenylurea Compounds, Cell Biology, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Microscopy, Fluorescence, Gene Expression Regulation, Solubility, Biochemistry and Cell Biology, knockout mice

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec122ebeeeb6511b45055a2a08101c45
https://europepmc.org/articles/PMC5515292/

المؤلفون: Kunio Sugahara, Shinichiro Koike, Fumiaki Yoshizawa

المصدر: The FASEB Journal. 28

مصطلحات موضوعية: Biochemistry, Oral administration, Chemistry, Rat liver, Genetics, Isoleucine, Molecular Biology, Protein expression, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c8a3b23810b41ac54dc616f4aa042dad
https://doi.org/10.1096/fasebj.28.1_supplement.820.3