المؤلفون: Shilpi Khare, Steven L Roach, S Whitney Barnes, Dominic Hoepfner, John R Walker, Arnab K Chatterjee, R Jeffrey Neitz, Michelle R Arkin, Case W McNamara, Jaime Ballard, Yin Lai, Yue Fu, Valentina Molteni, Vince Yeh, James H McKerrow, Richard J Glynne, Frantisek Supek

المصدر: PLoS Pathogens, Vol 11, Iss 7, p e1005058 (2015)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4506092?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

URL الوصول: https://doaj.org/article/74c1eaf7a3e241ef97a84b81f3a2894a

المؤلفون: Shilpi Khare Saikia, Rakesh Pandey

المصدر: Advances in Agriculture, Vol 2014 (2014)

مصطلحات موضوعية: Agriculture (General), S1-972

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2356-654X; https://doaj.org/toc/2314-7539

URL الوصول: https://doaj.org/article/3dba35c49ec84e37a92e3b3d33b3ffcb

المؤلفون: Shilpi Khare, Carole L. Linster, Steven G. Clarke

المصدر: PLoS ONE, Vol 8, Iss 5 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3643881; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/5b703c3cd99d45f998e910e69f202a28

المؤلفون: Paola V Castro, Shilpi Khare, Brian D Young, Steven G Clarke

المصدر: PLoS ONE, Vol 7, Iss 1, p e29984 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3261173?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/1b1ac5761b3746e49fb2b262a2828b21

المؤلفون: Shilpi Khare, Carole L Linster, Steven G Clarke

المصدر: PLoS ONE, Vol 6, Iss 6, p e20850 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3113807?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3b206b39e77e4c57bea68df1798a4154

المؤلفون: Pramod W. Ramteke, Shilpi Khare, Thiruneelakantan Srinath

المصدر: The Journal of General and Applied Microbiology. 2001, 47(6):307

المؤلفون: Christopher R. Smith, Dan Chen, James G. Christensen, René Coulombe, James Féthière, Robin J. Gunn, Johan Hollander, Benjamin Jones, John M. Ketcham, Shilpi Khare, Jon Kuehler, J. David Lawson, Matthew A. Marx, Peter Olson, Kelly E. Pearson, Cynthia Ren, Denise Tsagris, Thirumalaiselvi Ulaganathan, Inge Van’t Veer, Xiaolun Wang, Anthony Ivetac

مصطلحات موضوعية: Biochemistry, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, stimulated ras activation, ray cocrystal structures, binding modes determined, based screening strategy, sos1 inhibitor bi, kras ppi inhibitors, kras inhibitors, selective sos1, therapeutic interest, mediate rtk, mapk rebound, identify x, clinical investigation

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Five_SOS2_Fragment_Hits_with_Binding_Modes_Determined_by_SOS2_X_Ray_Cocrystallography/24917166

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c02140.s001
https://figshare.com/articles/journal_contribution/Discovery_of_Five_SOS2_Fragment_Hits_with_Binding_Modes_Determined_by_SOS2_X_Ray_Cocrystallography/24917166

المؤلفون: John M. Ketcham, Jacob Haling, Shilpi Khare, Vickie Bowcut, David M. Briere, Aaron C. Burns, Robin J. Gunn, Anthony Ivetac, Jon Kuehler, Svitlana Kulyk, Jade Laguer, J. David Lawson, Krystal Moya, Natalie Nguyen, Lisa Rahbaek, Barbara Saechao, Christopher R. Smith, Niranjan Sudhakar, Nicole C. Thomas, Laura Vegar, Darin Vanderpool, Xiaolun Wang, Larry Yan, Peter Olson, James G. Christensen, Matthew A. Marx

المصدر: Journal of Medicinal Chemistry. 65:9678-9690

مصطلحات موضوعية: Proto-Oncogene Proteins p21(ras), Mice, Acetonitriles, Pyrimidines, Cell Line, Tumor, Mutation, Drug Discovery, Animals, Brain, Humans, Molecular Medicine, SOS1 Protein, Piperazines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe52dccfc91d77da8d18ff2be215969
https://doi.org/10.1021/acs.jmedchem.2c00741

المؤلفون: Negi, Hema, Saikia, Shilpi Khare, Pandey, Rakesh

المساهمون: National Institutes of Health, Indian Council of Medical Research

المصدر: The Journals of Gerontology: Series A ; volume 72, issue 12, page 1614-1619 ; ISSN 1079-5006 1758-535X

الاتاحة: http://dx.doi.org/10.1093/gerona/glx118
http://academic.oup.com/biomedgerontology/article-pdf/72/12/1614/24371398/glx118.pdf

المؤلفون: Glen Spraggon, Smith Jeffrey M, Chianelli Donatella, Advait Nagle, Christian Wiesmann, Xiaodong Liu, Yongping Xie, Richard J. Sciotti, Todd Groessl, Kevin Johnson, Xianzhong Liu, Celine Be, Christopher Thompson, Yin H. Lai, Jan Jiricek, Patrick J Rudewicz, Brandon S. Pybus, Casey J. N. Mathison, Valentina Molteni, Honnappa Srinivas, Richard Glynne, Jaime Ballard, Agnes Biggart, Diana Caridha, Andreas Hein, Ashley Mitchell Berman, Mu-Yun Gao, Lauren C. Davis, Michael Shapiro, Michael Gibney, Yen Liang Chen, Vince Yeh, Fabian K. Eggimann, Badry Bursulaya, Mara Kreishman-Deitrick, Lerario Isabelle K, Fang Liang, Shilpi Khare, Wendy Richmond, Srinivasa P. S. Rao, Frantisek Supek, Tove Tuntland, Alexandre Luneau

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: Chagas disease, Antiprotozoal Agents, Drug Annotation, 01 natural sciences, Rats, Sprague-Dawley, Mice, 03 medical and health sciences, Dogs, parasitic diseases, Drug Discovery, medicine, Animals, Humans, African trypanosomiasis, Oxazoles, Leishmania major, 030304 developmental biology, Mice, Inbred BALB C, 0303 health sciences, Chemistry, Leishmania tarentolae, Leishmaniasis, Triazoles, medicine.disease, Virology, Rats, 0104 chemical sciences, 3. Good health, Macaca fascicularis, 010404 medicinal & biomolecular chemistry, Pyrimidines, Visceral leishmaniasis, Liver, Proteasome, Proteasome inhibitor, Leishmaniasis, Visceral, Molecular Medicine, Proteasome Inhibitors, Leishmania donovani, Clearance, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37584f6654d3dc34b0710ef1ed444634
https://doi.org/10.1021/acs.jmedchem.0c00499

المؤلفون: Shilpi Khare, Niranjan Sudhakar, Jade Laguer, David M. Briere, Larry Yan, Allan Hebbert, Andrew Calinisan, Lars D. Engstrom, Fadia Qiryaqos, Peter Olson, James G. Christensen, Jacob R. Haling

المصدر: Cancer Research. 83:3499-3499

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ea99e6ddf20a56522bbb06dad376405
https://doi.org/10.1158/1538-7445.am2023-3499

المؤلفون: John M. Ketcham, David M. Briere, Aaron C. Burns, James G. Christensen, Robin J. Gunn, Jacob Haling, Anthony Ivetac, Shilpi Khare, Jon Kuehler, Svitlana Kulyk, Jade Laguer, John D. Lawson, Krystal Moya, Natalie Nguyen, Peter Olson, Lisa Rahbaek, Christopher R. Smith, Niranjan Sudhakar, Nicole C. Thomas, Darin Vanderpool, Xiaolun Wang, Matthew A. Marx

المصدر: Cancer Research. 82:LB505-LB505

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::90876ca61e88494e7565b576662f0b19
https://doi.org/10.1158/1538-7445.am2022-lb505

المؤلفون: Shilpi Khare, Niranjan Sudhakar, David M. Briere, Larry Yan, Lars D. Engstrom, Jade Laguer, James Medwid, Laura Vegar, Darin Vanderpool, Matthew A. Marx, John M. Ketcham, James G. Christensen, Peter Olson, Jacob R. Haling

المصدر: Cancer Research. 82:LB193-LB193

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fbe107627aea203ba49c9f40899a61e8
https://doi.org/10.1158/1538-7445.am2022-lb193

المؤلفون: John M. Ketcham, Shilpi Khare, Niranjan Sudhakar, David M. Briere, Larry Yan, Jade Laguer, Laura Vegar, Darin Vanderpool, Jill Hallin, Lauren Hargis, Vickie Bowcut, David Lawson, Robin J. Gunn, Anthony Ivetac, Nicole C. Thomas, Barbara Saechao, Natalie Nguyen, Jeffrey Clarine, Lisa Rahbaek, Christopher R. Smith, Aaron C. Burns, Matthew A. Marx, James G. Christensen, Peter Olson, Jacob R. Haling

المصدر: Cancer Research. 82:ND02-ND02

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7d2787a74c7485ec82fe00545619a049
https://doi.org/10.1158/1538-7445.am2022-nd02

المؤلفون: Saikia, Shilpi Khare, Gupta, Rupali, Pant, Aakanksha, Pandey, Rakesh

المصدر: Journal of Exposure Science & Environmental Epidemiology ; volume 24, issue 2, page 180-184 ; ISSN 1559-0631 1559-064X

الاتاحة: http://dx.doi.org/10.1038/jes.2013.66
https://www.nature.com/articles/jes201366.pdf
https://www.nature.com/articles/jes201366

المؤلفون: Advait Nagle, Ben G. Wen, Srinivasa P. S. Rao, Monique Stinson, Glenn C. Federe, Richard Glynne, Yin H. Lai, Ianne C. Rivera, Ansgar Brock, Michael Shapiro, Hazel X. Y. Koh, John D. Venable, Jaime Ballard, J. Robert Gillespie, Badry Bursulaya, Glen Spraggon, Xianzhong Liu, Mu-Yun Gao, Vince Yeh, Tove Tuntland, Fang Liang, S. Whitney Barnes, Todd Groessl, Shilpi Khare, Elmarie Myburgh, Agnes Biggart, Lauren C. Davis, Jocelyn Tan, Pranab Mishra, Frantisek Supek, Casey J. N. Mathison, Valentina Molteni, Jeremy C. Mottram, Frederick S. Buckner, John R. Walker

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, Chagas disease, Proteasome Endopeptidase Complex, 030106 microbiology, Trypanosoma brucei, Article, 03 medical and health sciences, Inhibitory Concentration 50, Mice, Species Specificity, parasitic diseases, medicine, Animals, Chymotrypsin, Humans, Chagas Disease, Molecular Targeted Therapy, Kinetoplastida, Trypanosoma cruzi, Leishmaniasis, Multidisciplinary, biology, Molecular Structure, Triazoles, Leishmania, biology.organism_classification, medicine.disease, Virology, 3. Good health, Disease Models, Animal, 030104 developmental biology, Pyrimidines, Trypanosomiasis, African, Proteasome, Parasitology, Female, Trypanosomiasis, Proteasome Inhibitors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bc027b1d63c94a64adf691d28ee40c
http://europepmc.org/articles/PMC5161665

المؤلفون: Simon Schenk, Matthew R. Bliss, Thomas D.Y. Chung, Janna Kiselar, Michael P Hedrick, Tomas Mustelin, Laurie A. Bankston, Fusayo Yamamoto, Vida Zhang, Jiwen Zou, Jinghua Yu, Yingge Liu, Stephanie M. Stanford, Andrey A. Bobkov, Robert Ardecky, Nunzio Bottini, Antonio Barquilla, Shilpi Khare, Gregory W. Cadwell, Alexander E. Aleshin, Anthony B. Pinkerton, Santhi Ganji, Robert C. Liddington

المصدر: Nature chemical biology, vol 13, iss 6

مصطلحات موضوعية: 0301 basic medicine, Drug Evaluation, Preclinical, Mice, Obese, Type 2 diabetes, Protein tyrosine phosphatase, Pharmacology, Obese, Mice, Models, Tyrosine, Enzyme Inhibitors, Mice, Knockout, biology, Molecular Structure, Chemistry, Diabetes, Preclinical, 3. Good health, Biochemistry, Phosphorylation, Type 2, Biochemistry & Molecular Biology, Knockout, Phosphatase, Models, Biological, Small Molecule Libraries, 03 medical and health sciences, Inhibitory Concentration 50, Structure-Activity Relationship, Medicinal and Biomolecular Chemistry, Insulin resistance, Diabetes mellitus, medicine, Diabetes Mellitus, Animals, Molecular Biology, Metabolic and endocrine, Binding Sites, 030102 biochemistry & molecular biology, Prevention, Cell Biology, medicine.disease, Biological, Enzyme Activation, Molecular Weight, Insulin receptor, 030104 developmental biology, Diabetes Mellitus, Type 2, biology.protein, Drug Evaluation, Biochemistry and Cell Biology, Protein Tyrosine Phosphatases, Gene Deletion

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c1031f609979e1dab8e8a9ec92ae41
https://escholarship.org/uc/item/2ck6d6dq

المؤلفون: Frantisek Supek, Naveen Kumar Chennamaneni, Advait Nagle, Shilpi Khare, Arun Kumar, Michael H. Gelb, Nagendar Pendem, Casey J. N. Mathison, Valentina Molteni, Frederick S. Buckner, Andriy Buchynskyy

المصدر: Chemical Reviews

مصطلحات موضوعية: Post-kala-azar dermal leishmaniasis, Miltefosine, biology, Chemistry, 1. No poverty, Antiprotozoal Agents, Leishmaniasis, Paromomycin, General Chemistry, Review, medicine.disease, biology.organism_classification, Leishmania, Virology, 3. Good health, Sandfly, Visceral leishmaniasis, Cutaneous leishmaniasis, Trypanosomiasis, Drug Design, parasitic diseases, medicine, Humans, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9d861e087076b565b571d2925592ba
http://europepmc.org/articles/PMC4633805

المؤلفون: Negi, Hema, Saikia, Shilpi Khare, Kanaujia, Ranjana, Jaiswal, Satish, Pandey, Rakesh

المساهمون: NIH Office of Research Infrastructure Programs, Indian Council of Medical Research

المصدر: Environmental Toxicology and Pharmacology ; volume 53, page 105-110 ; ISSN 1382-6689

الاتاحة: http://dx.doi.org/10.1016/j.etap.2017.05.004
https://api.elsevier.com/content/article/PII:S1382668917301254?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1382668917301254?httpAccept=text/plain

المؤلفون: Yue Fu, Case W. McNamara, Vince Yeh, Richard Glynne, James H. McKerrow, Arnab K. Chatterjee, John R. Walker, Jaime Ballard, Frantisek Supek, Valentina Molteni, Yin Lai, R. Jeffrey Neitz, Dominic Hoepfner, Steven L. Roach, S. Whitney Barnes, Michelle R. Arkin, Shilpi Khare

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 11, Iss 7, p e1005058 (2015)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, Antifungal Agents, Cytochrome, Trypanosoma cruzi, Immunology, Respiratory chain, Antimycin A, Microbiology, Electron Transport, chemistry.chemical_compound, Mice, Oxygen Consumption, Virology, Genetics, Animals, Chagas Disease, lcsh:QH301-705.5, Molecular Biology, biology, Myxothiazol, Cytochrome bc1, Drug discovery, Cytochrome b, Cytochrome c, Genomics, Cytochromes b, Molecular biology, 3. Good health, Mitochondria, lcsh:Biology (General), chemistry, Biochemistry, Coenzyme Q – cytochrome c reductase, Mutation, biology.protein, Parasitology, lcsh:RC581-607, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dc3f3483963d81aa5dcb49fed59c85
http://europepmc.org/articles/PMC4506092