المؤلفون: Lyndon J. Mitnaul, Jenny Tian, Charlotte Burton, My-Hanh Lam, Yuping Zhu, Steve H. Olson, Jonathan E. Schneeweis, Paul Zuck, Shilpa Pandit, Matt Anderson, Milana M. Maletic, Sherman T. Waddell, Samuel D. Wright, Carl P. Sparrow, Erik G. Lund

المصدر: Journal of Lipid Research, Vol 48, Iss 2, Pp 472-482 (2007)

مصطلحات موضوعية: bodipy-labeled, synthetic high density lipoprotein, micelles, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520436843; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/d21b6e928b9c41379a4ec8c290c474c3

المؤلفون: Carolyn Bahnck-Teets, Xu Min, Lehua Chang, Tracy L. Diamond, M. Katharine Holloway, John F. Fay, David Jonathan Bennett, John A. Mccauley, Jurgen Schulz, Marie Loughran, Peter D. Williams, Alejandro Crespo, Andrew Stamford, Hua-Poo Su, Michael D. Miller, Kartik M. Keertikar, Christopher J. Bungard, Catherine M. Wiscount, Bin Zhong, Jeanine E. Ballard, Sherman T. Waddell, Steven S. Carroll, Tao Ji, Jesse J. Manikowski, Bin Hu, Xin-jie Chu, Gregori J. Morriello, William J. Morris, Michael P. Dwyer

المصدر: ACS Medicinal Chemistry Letters. 8:1292-1297

مصطلحات موضوعية: chemistry.chemical_classification, Bicyclic molecule, biology, 010405 organic chemistry, Stereochemistry, Protease binding, Organic Chemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Sulfonamide, Enzyme binding, Aspartate binding, Piperazine, chemistry.chemical_compound, chemistry, HIV-1 protease, Drug Discovery, biology.protein, Protease inhibitor (pharmacology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6240d0128d9c35a558caa2cfbba15fa5
https://doi.org/10.1021/acsmedchemlett.7b00386

المؤلفون: Edward C. Sherer, Robert K. Orr, Jamie M. McCabe Dunn, Yong Zhang, Aaron X. Sun, Yu-hong Lam, John E. Stelmach, Sherman T. Waddell, Melisa Shiroda, Subharekha Raghavan, Alan Whitehead

المصدر: Organic letters. 19(17)

مصطلحات موضوعية: Steric effects, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, 010402 general chemistry, Ring (chemistry), Highly selective, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences, Nucleophile, Electrophile, Physical and Theoretical Chemistry, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5309e4dd64177ba0f3a8690e863ed2f0
https://pubmed.ncbi.nlm.nih.gov/28812897

المؤلفون: Gloria C. Koo, Martin S. Springer, Lorraine Malkowitz, Douglas W. Kawka, Kang Cheng, Qi Luo, Serguei Stepaniants, Kenneth K. Wu, Irwin I. Singer, Jeffrey Yuan, Andrew S. Plump, Cheryl B. Le Grand, Jun Zhu, Milana Maletic, Samuel D. Wright, James M. Balkovec, Gloria J.-F. Ding, Sherman T. Waddell, Xia Yang, Rolf Thieringer, Kashmira Shah, Pek Yee Lum, Mingjuan Jane Luo, I-Ming Wang, Anne Hermanowski-Vosatka

المصدر: Physiological Genomics. 45:47-57

مصطلحات موضوعية: Vasculitis, Physiology, Genes, MHC Class II, 11β hsd1, Dehydrogenase, Laser Capture Microdissection, Biology, Proinflammatory cytokine, Mice, Apolipoproteins E, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Gene expression, Genetics, medicine, Animals, Enzyme Inhibitors, Glucocorticoids, Mice, Knockout, Gene Expression Profiling, Atherosclerosis, Microarray Analysis, medicine.disease, Lipids, Gene expression profiling, Cholesterol, Gene Expression Regulation, Immunology, Etiology, Metabolic syndrome, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62219a7783ded2299858a49a0cadc560
https://doi.org/10.1152/physiolgenomics.00109.2012

المؤلفون: John W. Phillips, Xin Gu, Mihai Petcu, Molly M. Lin, Ronald E. Painter, Michel Gallant, Lynn Miesel, Kathryn Skorey, Kenneth E. Wilson, David Claveau, Liliana L. Benton-Perdomo, Kathleen Deschamps, Christopher M. Tan, Katherine Young, Andrew Galgoci, John Tam, Christian Lebeau-Jacob, Alexandre Caron, Young-Whan Park, Suzy Lee, Simon Wong, Patrick Beaulieu, Craig A. Parish, Aimie M. Ogawa, Josiane Lafleur, Alex G. Therien, Nancy J. Kevin, Sherman T. Waddell, Robert G. K. Donald, Penny Sue Leavitt, Mary Ann Powles, Joann Huber, Anna A. Michels

المصدر: Antimicrobial Agents and Chemotherapy. 56:4662-4670

مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, Imipenem, Lipoglycopeptide, medicine.drug_class, Antibiotics, Microbial Sensitivity Tests, Biology, beta-Lactams, medicine.disease_cause, beta-Lactam Resistance, beta-Lactamases, Microbiology, Lipopeptides, Mice, chemistry.chemical_compound, Bacterial Proteins, Depsipeptides, polycyclic compounds, medicine, Animals, Humans, Experimental Therapeutics, Pharmacology (medical), Glycosides, Pharmacology, Depsipeptide, Mice, Inbred BALB C, Signal peptidase, Biphenyl Compounds, Serine Endopeptidases, Glycopeptides, Membrane Proteins, Biological Transport, Drug Synergism, Staphylococcal Infections, biochemical phenomena, metabolism, and nutrition, bacterial infections and mycoses, Methicillin-resistant Staphylococcus aureus, Anti-Bacterial Agents, Biphenyl compound, Infectious Diseases, chemistry, Staphylococcus aureus, Multigene Family, Drug Therapy, Combination, Female, Oligopeptides, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2bc01435a04348f73f58cdb283cf572
https://doi.org/10.1128/aac.00726-12

المؤلفون: Matt S. Anderson, Yuping Zhu, Carl P. Sparrow, Erik G. Lund, Jenny Tian, My-Hanh Lam, Lyndon J. Mitnaul, Samuel D. Wright, Paul Zuck, Sherman T. Waddell, Milana Maletic, Jonathan Schneeweis, Shilpa Pandit, Steve H. Olson, Charlotte Burton

المصدر: Journal of Lipid Research, Vol 48, Iss 2, Pp 472-482 (2007)

مصطلحات موضوعية: Endothelial lipase, micelles, Phospholipid, QD415-436, Phospholipase, Biochemistry, Fluorescence, Mice, chemistry.chemical_compound, Endocrinology, Animals, Humans, Fluorescent Dyes, Triglyceride lipase, Lipoprotein lipase, Molecular Structure, Triglyceride, Cholesterol, Substrate (chemistry), Lipase, Cell Biology, bodipy-labeled, chemistry, lipids (amino acids, peptides, and proteins), synthetic high density lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc4f239d6643858f7e73b81f5901acb
http://www.sciencedirect.com/science/article/pii/S0022227520436843

المؤلفون: Kenny K. Wong, Sreelatha G. Reddy, David L. Pompliano, Sherman T. Waddell, David W. Kuo

المصدر: Journal of the American Chemical Society. 121:1175-1178

مصطلحات موضوعية: chemistry.chemical_classification, Stereochemistry, General Chemistry, biochemical phenomena, metabolism, and nutrition, Enzymatic synthesis, Biochemistry, Catalysis, Murein biosynthesis, carbohydrates (lipids), Colloid and Surface Chemistry, Enzyme, chemistry, Cytoplasm, Yield (chemistry), bacteria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::89ee9b0edb778a03d52a7c02e40a82a7
https://doi.org/10.1021/ja983850b

المؤلفون: Laura D. Gegnas, Renee M. Chabin, Sreelatha G. Reddy, Kenny K. Wong, Sherman T. Waddell

المصدر: Bioorganic & Medicinal Chemistry Letters. 8:1643-1648

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, medicine.disease_cause, Biochemistry, Bacterial cell structure, Cell wall, chemistry.chemical_compound, Organophosphorus Compounds, Biosynthesis, Cell Wall, Drug Discovery, Escherichia coli, medicine, Peptide Synthases, Molecular Biology, Antibacterial agent, chemistry.chemical_classification, Molecular Structure, biology, Organic Chemistry, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Peptidoglycan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083f7685d89b797885d1239f3dd17964
https://doi.org/10.1016/s0960-894x(98)00285-6

المؤلفون: Gina M. Santorelli, Amy C. Graham, Sherman T. Waddell, James L. Occi, Timothy A. Blizzard

المصدر: Bioorganic & Medicinal Chemistry Letters. 8:1321-1326

مصطلحات موضوعية: medicine.drug_class, Clinical Biochemistry, Antibiotics, Molecular Conformation, Pharmaceutical Science, Microbial Sensitivity Tests, Azalide, Gram-Positive Bacteria, Methylation, Biochemistry, Clarithromycin, Drug Discovery, medicine, Organic chemistry, Molecular Biology, Antibacterial agent, Aza Compounds, Chemistry, Organic Chemistry, Chemical modification, Anti-Bacterial Agents, Molecular Medicine, Antibacterial activity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3df8483e64fb56103639be650afc55a
https://doi.org/10.1016/s0960-894x(98)00227-3

المؤلفون: Timothy A. Blizzard, Sherman T. Waddell, Amy C. Graham, James L. Occi, Gina M. Santorelli

المصدر: Bioorganic & Medicinal Chemistry Letters. 8:549-554

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Microbial Sensitivity Tests, Azalide, Gram-Positive Bacteria, Methylation, Biochemistry, Chemical synthesis, Drug Discovery, medicine, Molecular Biology, Antibacterial agent, chemistry.chemical_classification, Molecular Structure, Chemistry, Organic Chemistry, Aminoglycoside, Glycoside, Anti-Bacterial Agents, Erythromycin, Kinetics, Molecular Medicine, Antibacterial activity, Lactone, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a0f887612a8ecb8d9340e82b28ab0c
https://doi.org/10.1016/s0960-894x(98)00070-5

المؤلفون: Sherman T. Waddell, Gina M. Santorelli

المصدر: Tetrahedron Letters. 37:1971-1974

مصطلحات موضوعية: chemistry.chemical_classification, Double bond, medicine.drug_class, organic chemicals, Organic Chemistry, Cephalosporin, Ether, Biochemistry, Chloride, chemistry.chemical_compound, chemistry, Drug Discovery, medicine, Organic chemistry, Methylene, Isomerization, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::902e7ff8a7eed814ba67ff416925635d
https://doi.org/10.1016/0040-4039(96)00183-9

المؤلفون: Jon G. Sundelof, Earl St. Rose, Kenneth J. Wildonger, Karen Dorso, Timothy A. Blizzard, Sandra P. Szumiloski, Ronald W. Ratcliffe, Sherman T. Waddell, Joyce Kohler, Joann Huber, Robert R. Wilkening, Gail G. Hammond

المصدر: Bioorganic & Medicinal Chemistry Letters. 5:1427-1432

مصطلحات موضوعية: Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, biochemical phenomena, metabolism, and nutrition, Anti mrsa, bacterial infections and mycoses, medicine.disease_cause, Biochemistry, Combinatorial chemistry, Staphylococcus aureus, Drug Discovery, medicine, Molecular Medicine, Pharmacophore, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f3e7c77a7ce92529b58445a9083e9a7f
https://doi.org/10.1016/0960-894x(95)00235-l

المؤلفون: Sherman T. Waddell, Ronald Breslow, David Wiedenfeld, Peter J. Duggan

المصدر: Tetrahedron Letters. 36:2707-2710

مصطلحات موضوعية: chemistry.chemical_compound, Monomer, Water soluble, Denticity, chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Binding properties, macromolecular substances, Biochemistry, Affinities, Cyclophane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::641fe5968bcc626b678e4176dc37a443
https://doi.org/10.1016/0040-4039(95)00373-k

المؤلفون: Jisong Cui, Sherman T. Waddell, Kashmira Shah, David R. Bauman, Diane Shevell, Sloan Stribling, Joe Metzger, Xin Gu, Alan Whitehead, Xiuying Ma, Hratch J. Zokian, Nancy J. Kevin, Xiaolan Shen, Lisa Contino, Lee-Yuh Pai, Margarita Garcia-Calvo

المصدر: Bioorganicmedicinal chemistry letters. 23(12)

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, 11β hsd1, Pharmacology, Biochemistry, Mice, In vivo, Rats, Inbred SHR, Drug Discovery, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Animals, Humans, Spontaneous hypertensive rat, Enzyme Inhibitors, Molecular Biology, Mice, Knockout, Chemistry, Organic Chemistry, Triazoles, In vitro, Rats, Clinical trial, Blood pressure, Hypertension, Molecular Medicine, Blood pressure lowering, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98554e1c6cf3318a7e55193c0d8ccb5d
https://pubmed.ncbi.nlm.nih.gov/23659858

المؤلفون: Timothy A. Blizzard, Sherman T. Waddell

المصدر: Bioorganic & Medicinal Chemistry Letters. 3:1757-1760

مصطلحات موضوعية: Chemistry, Stereochemistry, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Antibiotics, Pharmaceutical Science, Azalide, Biochemistry, Chemical synthesis, Semisynthesis, Nitrogen atom, Drug Discovery, medicine, Molecular Medicine, Molecule, Molecular Biology, Antibacterial agent, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b4284806df478f16788f3d82ccdaa44f
https://doi.org/10.1016/s0960-894x(00)80057-8

المؤلفون: Timothy A. Blizzard, Sherman T. Waddell

المصدر: Tetrahedron Letters. 34:5385-5388

مصطلحات موضوعية: Ring size, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, medicine, Azalide, Ring (chemistry), Biochemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::037bbb4b1cda389bb7d2836f54e798c5
https://doi.org/10.1016/s0040-4039(00)73915-3

المؤلفون: Sherman T. Waddell, James M. Balkovec, Jasminka Dragovic, Michael J. Szymonifka, Steven S. Mundt, Milana Maletic, Anne H. Vosatka, Hratch J. Zokian, Rolf Thieringer, Kashmira Shah, Kathy Lyons, Aaron H. Leeman

المصدر: Bioorganicmedicinal chemistry letters. 21(8)

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Dehydrogenase, Biochemistry, Chemical synthesis, Sulfone, chemistry.chemical_compound, Bridged Bicyclo Compounds, Mice, Structure-Activity Relationship, In vivo, 11-beta-Hydroxysteroid Dehydrogenase Type 2, Drug Discovery, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Structure–activity relationship, Animals, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Metabolic Syndrome, biology, Bicyclic molecule, Organic Chemistry, Triazoles, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df897394b2283495c69f7ae2d03ebd2
https://pubmed.ncbi.nlm.nih.gov/21421311

المؤلفون: Steven S. Mundt, James M. Balkovec, Sherman T. Waddell, Wanying Sun, Milana Maletic, Kathy Lyons, Kashmira Shah, Hratch J. Zokian

المصدر: Bioorganicmedicinal chemistry letters. 21(7)

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Dehydrogenase, Biochemistry, Isozyme, 11β-hydroxysteroid dehydrogenase type 1, In vivo, Drug Discovery, 11-beta-Hydroxysteroid Dehydrogenase Type 1, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Pregnane X receptor, biology, Organic Chemistry, Triazoles, In vitro, Enzyme, Nuclear receptor, chemistry, biology.protein, Molecular Medicine, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18597b10cb42210b968767b3e3062e94
https://pubmed.ncbi.nlm.nih.gov/21334894

المؤلفون: Kenneth B. Wiberg, R. E. Rosenberg, Sherman T. Waddell

المصدر: ChemInform. 24

مصطلحات موضوعية: Pentane, chemistry.chemical_classification, chemistry.chemical_compound, Propellane, chemistry, Bicyclic molecule, General Medicine, Bridged compounds, Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::659e635c5ffabb7bc44b79e820153942
https://doi.org/10.1002/chin.199305030

المؤلفون: Timothy A. Blizzard, Sherman T. Waddell, George A. Doss

المصدر: ChemInform. 24

مصطلحات موضوعية: Mesylate, Stereochemistry, General Medicine, Carbohydrate, Ring (chemistry), law.invention, chemistry.chemical_compound, chemistry, Nucleophile, Relay, law, Intramolecular force, Alkoxy group, Azide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0315c397dbe283a21835f09992d7b8c9
https://doi.org/10.1002/chin.199338256