المؤلفون: Ozonoff, Al, Ehrlich, Lauren IR, Melamed, Esther, Sesma, Ana Fernandez, Simon, Viviana, Pulendran, Bali, Nadeau, Kari C, Davis, Mark M, McCoey, Grace A, Sekaly, Rafick, Baden, Lindsey R, Levy, Ofer, Schaenman, Joanna, Reed, Elaine F, Shaw, Albert C, Hafler, David A, Montgomery, Ruth R, Kleinstein, Steven H, Becker, Patrice M, Augustine, Alison D, Calfee, Carolyn S, Erle, David J, DeBakey, Michael E, Corry, David B, Kheradmand, Farrah, Atkinson, Mark A, Brakenridge, Scott C, Higuita, Nelson I Agudelo, Metcalf, Jordan P, Hough, Catherine L, Messer, William B, Kraft, Monica, Bime, Chris, Peters, Bjoern, Milliren, Carly E, Syphurs, Caitlin, McEnaney, Kerry, Barton, Brenda, Lentucci, Claudia, Saluvan, Mehmet, Chang, Ana C, Hoch, Annmarie, Albert, Marisa, Shaheen, Tanzia, Kho, Alvin T, Liu, Shanshan, Thomas, Sanya, Chen, Jing, Murphy, Maimouna D, Cooney, Mitchell, Hayati, Arash Nemati, Bryant, Robert, Abraham, James, Jayavelu, Naresh Doni, Presnell, Scott, Jancsyk, Tomasz, Maguire, Cole, Qi, Jingjing, Lee, Brian, Fourati, Slim, Esserman, Denise A, Guan, Leying, Gygi, Jeremy, Pawar, Shrikant, Brito, Anderson, Fragiadakis, Gabriela K, Patel, Ravi, Overton, James A, Vita, Randi, Westendorf, Kerstin, Shannon, Casey P, Tebbutt, Scott J, Thyagarajan, Rama V, Rousseau, Justin F, Wylie, Dennis, Triplett, Todd A, Kojic, Erna, Chinthrajah, Sharon, Ahuja, Neera, Rogers, Angela J, Artandi, Maja, Geng, Linda, Yendewa, George, Powell, Debra L, Kim, James N, Simmons, Brent, Goonewardene, I Michael, Smith, Cecilia M, Martens, Mark, Sherman, Amy C, Walsh, Stephen R, Issa, Nicolas C, Salehi-Rad, Ramin, Dela Cruz, Charles, Farhadian, Shelli, Iwasaki, Akiko, Ko, Albert I, Anderson, Evan J, Mehta, Aneesh K, Sevransky, Jonathan E

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Immunology, Coronaviruses, Infectious Diseases, Emerging Infectious Diseases, Lung, Inflammatory and immune system, Good Health and Well Being, Humans, COVID-19, Glycosylation, SARS-CoV-2, Glycosyltransferases, Complement System Proteins, Immunoglobulin M, IMPACC Network

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2955t2wq
https://escholarship.org/content/qt2955t2wq/qt2955t2wq.pdf

المؤلفون: McEnaney, Kerry, Barton, Brenda, Lentucci, Claudia, Saluvan, Mehmet, Chang, Ana C, Hoch, Annmarie, Albert, Marisa, Shaheen, Tanzia, Kho, Alvin T, Thomas, Sanya, Chen, Jing, Murphy, Maimouna D, Cooney, Mitchell, Hayati, Arash Nemati, Bryant, Robert, Abraham, James, Presnell, Scott, Jancsyk, Tomasz, Maguire, Cole, Lee, Brian, Fourati, Slim, Esserman, Denise A, Guan, Leying, Gygi, Jeremy, Pawar, Shrikant, Brito, Anderson, Fragiadakis, Gabriela K, Patel, Ravi, Tebbutt, Scott J, Overton, James A, Vita, Randi, Westendorf, Kerstin, Thyagarajan, Rama V, Rousseau, Justin F, Wylie, Dennis, Triplett, Todd A, Kojic, Erna, Chinthrajah, Sharon, Ahuja, Neera, Rogers, Angela J, Artandi, Maja, Yendewa, George, Powell, Debra L, Kim, James N, Simmons, Brent, Goonewardene, I Michael, Smith, Cecilia M, Martens, Mark, Sherman, Amy C, Walsh, Stephen R, Issa, Nicolas C, Salehi-Rad, Ramin, Dela Cruz, Charles, Farhadian, Shelli, Iwasaki, Akiko, Ko, Albert I, Anderson, Evan J, Mehta, Aneesh K, Sevransky, Jonathan E, Leligdowicz, Aleksandra, Matthay, Michael A, Singer, Jonathan P, Kangelaris, Kirsten N, Hendrickson, Carolyn M, Krummel, Matthew F, Woodruff, Prescott G, Anderson, Matthew L, Guirgis, Faheem W, Drevets, Douglas A, Brown, Brent R, Siegel, Sarah AR, Lu, Zhengchun, Mosier, Jarrod, Kimura, Hiroki, Khor, Bernard, Rahman, Adeeb, Stadlbauer, Daniel, Dutta, Jayeeta, Gonzalez-Reiche, Ana Silvia, van de Guchte, Adriana, Carreño, Juan Manuel, Singh, Gagandeep, Raskin, Ariel, Tcheou, Johnstone, Bielak, Dominika, Kawabata, Hisaaki, Xie, Hui, Kelly, Geoffrey, Patel, Manishkumar, Nie, Kai, Yellin, Temima, Fried, Miriam, Sullivan, Leeba, Morris, Sara, Sieg, Scott, van Zalm, Patrick, Fatou, Benoit, Mendez, Kevin, Lasky-Su, Jessica, Hutton, Scott R

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Health Services and Systems, Biomedical and Clinical Sciences, Health Sciences, Coronaviruses, Infectious Diseases, Lung, Emerging Infectious Diseases, Prevention, Clinical Research, 2.1 Biological and endogenous factors, Good Health and Well Being, Female, Humans, SARS-CoV-2, COVID-19, B-Lymphocytes, Body Fluids, Disease Progression, Phenotype, IMPACC Network

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7c60n279
https://escholarship.org/content/qt7c60n279/qt7c60n279.pdf

المؤلفون: Amodio, Donato, Angelidou, Asimenia, Cotugno, Nicola, Sherman, Amy C, Levy, Ofer, Palma, Paolo

المصدر: Vaccine ; ISSN:1873-2518 ; Volume:43 ; Issue:Pt 2

مصطلحات موضوعية: Adjuvants, Adversomics, Correlates of protection, Efficacy, Safety, Vaccinology, Vulnerable populations

Relation: https://doi.org/10.1016/j.vaccine.2024.126477; https://pubmed.ncbi.nlm.nih.gov/39608233

الاتاحة: https://doi.org/10.1016/j.vaccine.2024.126477
https://pubmed.ncbi.nlm.nih.gov/39608233

المؤلفون: Phadke, Varun K., Gromer, Daniel J., Rebolledo, Paulina A., Graciaa, Daniel S., Wiley, Zanthia, Sherman, Amy C., Scherer, Erin M., Leary, Maranda, Girmay, Tigisty, McCullough, Michele P., Min, Ji-Young, Capone, Stefania, Sommella, Andrea, Vitelli, Alessandra, Retallick, Jamie, Seetahal, Janine, Koller, Mark, Tsong, Rachel, Neill-Gubitz, Hannah, Mulligan, Mark J., Rouphael, Nadine G.

المساهمون: National Institute of Allergy and Infectious Diseases Division of Microbiology and Infectious Diseases

المصدر: Vaccine ; volume 42, issue 26, page 126441 ; ISSN 0264-410X

الاتاحة: https://doi.org/10.1016/j.vaccine.2024.126441
https://api.elsevier.com/content/article/PII:S0264410X2401123X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0264410X2401123X?httpAccept=text/plain

المؤلفون: Little, Jessica S, Coughlin, Cassie, Hsieh, Candace, Lanza, Meaghan, Huang, Wan Yi, Kumar, Aishwarya, Dandawate, Tanvi, Tucker, Robert, Gable, Paige, Vazquez Deida, Axel A, Moulton-Meissner, Heather, Stevens, Valerie, McAllister, Gillian, Ewing, Thomas, Diaz, Maria, Glowicz, Janet, Winkler, Marisa L, Pecora, Nicole, Kubiak, David W, Pearson, Jeffrey C, Luskin, Marlise R, Sherman, Amy C, Woolley, Ann E, Brandeburg, Christina, Bolstorff, Barbara, McHale, Eileen, Fortes, Esther, Doucette, Matthew, Smole, Sandra, Bunnell, Craig, Gross, Anne, Platt, Dana, Desai, Sonali, Fiumara, Karen, Issa, Nicolas C, Baden, Lindsey R, Rhee, Chanu, Klompas, Michael, Baker, Meghan A

المصدر: Open Forum Infectious Diseases ; volume 11, issue 3 ; ISSN 2328-8957

الاتاحة: http://dx.doi.org/10.1093/ofid/ofae048
https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofae048/56420715/ofae048.pdf
https://academic.oup.com/ofid/article-pdf/11/3/ofae048/57090424/ofae048.pdf

المؤلفون: Lezo Ramirez, Daisy, Koleske, Emily, Ometoruwa, Omolola, Park Chang, Jun Bai, Kanwal, Urwah, Morreale, Nicholas, Avila Paz, Andres Alberto, Tong, Alexandra, Baden, Lindsey R., Sherman, Amy C., Walsh, Stephen R.

المساهمون: Merck

المصدر: Frontiers in Public Health ; volume 12 ; ISSN 2296-2565

الاتاحة: http://dx.doi.org/10.3389/fpubh.2024.1411970
https://www.frontiersin.org/articles/10.3389/fpubh.2024.1411970/full

المؤلفون: Randad, Pranay R, Pisanic, Nora, Kruczynski, Kate, Manabe, Yukari C, Thomas, David, Pekosz, Andrew, Klein, Sabra L, Betenbaugh, Michael J, Clarke, William A, Laeyendecker, Oliver, Caturegli, Patrizio P, Larman, H Benjamin, Detrick, Barbara, Fairley, Jessica K, Sherman, Amy C, Rouphael, Nadine, Edupuganti, Srilatha, Granger, Douglas A, Granger, Steve W, Collins, Matthew, Heaney, Christopher D

المصدر: JOURNAL OF CLINICAL MICROBIOLOGY. 59(1)

مصطلحات موضوعية: SARS-CoV-2, COVID-19, saliva, oral fluid, serology, antibody test, multiplex, diagnostics, immunoserology, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences, Microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/83b9d2d3

المؤلفون: Pisanic, Nora, Randad, Pranay R, Kruczynski, Kate, Manabe, Yukari C, Thomas, David L, Pekosz, Andrew, Klein, Sabra L, Betenbaugh, Michael J, Clarke, William A, Laeyendecker, Oliver, Caturegli, Patrizio P, Larman, H Benjamin, Detrick, Barbara, Fairley, Jessica K, Sherman, Amy C, Rouphael, Nadine, Edupuganti, Srilatha, Granger, Douglas A, Granger, Steve W, Collins, Matthew H, Heaney, Christopher D

المصدر: Journal of clinical microbiology. 59(1)

مصطلحات موضوعية: Saliva, Humans, Immunoglobulin A, Immunoglobulin G, Immunoglobulin M, Antibodies, Viral, Female, Male, Spike Glycoprotein, Coronavirus, COVID-19, SARS-CoV-2, COVID-19 Nucleic Acid Testing, Coronavirus Nucleocapsid Proteins, antibody test, diagnostics, immunoserology, multiplex, oral fluid, saliva, serology, Antibodies, Viral, Spike Glycoprotein, Coronavirus, Biological Sciences, Agricultural and Veterinary Sciences, Medical and Health Sciences, Microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2358n7ct

المؤلفون: Cheng, Matthew P, Gonzalez-Bocco, Isabel H, Arbonna-Haddad, Esther, Aleissa, Muneerah, Chen, Kaiwen, Zhou, Eric, Beluch, Katherine, Cho, Alyssa, Burchett, Sandra, Moulton, Elizabeth, Desjardins, Michaël, Baden, Lindsey R, Koo, Sophia, Letourneau, Alyssa R, Hammond, Sarah P, Ritz, Jerome, Soiffer, Robert, Issa, Nicolas C, Kim, Haesook T, Sherman, Amy C

المصدر: Journal of the Association of Medical Microbiology and Infectious Disease Canada ; ISSN 2371-0888

الاتاحة: https://doi.org/10.3138/jammi-2024-0016
https://utppublishing.com/doi/pdf/10.3138/jammi-2024-0016

المؤلفون: Branche, Angela R, Rouphael, Nadine G, Diemert, David J, Falsey, Ann R, Losada, Cecilia, Baden, Lindsey R, Frey, Sharon E, Whitaker, Jennifer A, Little, Susan J, Anderson, Evan J, Walter, Emmanuel B, Novak, Richard M, Rupp, Richard, Jackson, Lisa A, Babu, Tara M, Kottkamp, Angelica C, Luetkemeyer, Anne F, Immergluck, Lilly C, Presti, Rachel M, Bäcker, Martín, Winokur, Patricia L, Mahgoub, Siham M, Goepfert, Paul A, Fusco, Dahlene N, Malkin, Elissa, Bethony, Jeffrey M, Walsh, Edward E, Graciaa, Daniel S, Samaha, Hady, Sherman, Amy C, Walsh, Stephen R, Abate, Getahun, Oikonomopoulou, Zacharoula, El Sahly, Hana M, Martin, Thomas CS, Kamidani, Satoshi, Smith, Michael J, Ladner, Benjamin G, Porterfield, Laura, Dunstan, Maya, Wald, Anna, Davis, Tamia, Atmar, Robert L, Mulligan, Mark J, Lyke, Kirsten E, Posavad, Christine M, Meagher, Megan A, Stephens, David S, Neuzil, Kathleen M, Abebe, Kuleni, Hill, Heather, Albert, Jim, Telu, Kalyani, Mu, Jinjian, Lewis, Teri C, Giebeig, Lisa A, Eaton, Amanda, Netzl, Antonia, Wilks, Samuel H, Türeli, Sina, Makhene, Mamodikoe, Crandon, Sonja, Montefiori, David C, Makowski, Mat, Smith, Derek J, Nayak, Seema U, Roberts, Paul C, Beigel, John H, COVAIL Study Group

مصطلحات موضوعية: Humans, COVID-19 Vaccines, SARS-CoV-2, COVID-19, Broadly Neutralizing Antibodies

وصف الملف: application/pdf; application/zip; text/xml

Relation: https://www.repository.cam.ac.uk/handle/1810/357242

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/357242

المؤلفون: Branche, Angela R., Rouphael, Nadine G., Diemert, David J., Falsey, Ann R., Losada, Cecilia, Baden, Lindsey R., Frey, Sharon E., Whitaker, Jennifer A., Little, Susan J., Anderson, Evan J., Walter, Emmanuel B., Novak, Richard M., Rupp, Richard, Jackson, Lisa A., Babu, Tara M., Kottkamp, Angelica C., Luetkemeyer, Anne F., Immergluck, Lilly C., Presti, Rachel M., Bäcker, Martín, Winokur, Patricia L., Mahgoub, Siham M., Goepfert, Paul A., Fusco, Dahlene N., Malkin, Elissa, Bethony, Jeffrey M., Walsh, Edward E., Graciaa, Daniel S., Samaha, Hady, Sherman, Amy C., Walsh, Stephen R., Abate, Getahun, Oikonomopoulou, Zacharoula, El Sahly, Hana M., Martin, Thomas C. S., Kamidani, Satoshi, Smith, Michael J., Ladner, Benjamin G., Porterfield, Laura, Dunstan, Maya, Wald, Anna, Davis, Tamia, Atmar, Robert L., Mulligan, Mark J., Lyke, Kirsten E., Posavad, Christine M., Meagher, Megan A., Stephens, David S., Neuzil, Kathleen M., Abebe, Kuleni

المساهمون: U.S. Department of Health & Human Services | NIH | National Cancer Institute

المصدر: Nature Medicine ; volume 29, issue 9, page 2334-2346 ; ISSN 1078-8956 1546-170X

الاتاحة: http://dx.doi.org/10.1038/s41591-023-02503-4
https://www.nature.com/articles/s41591-023-02503-4.pdf
https://www.nature.com/articles/s41591-023-02503-4

المؤلفون: Kokogho, Afoke, Crowell, Trevor A, Aleissa, Muneerah, Lupan, Ana-Mihaela, Davey, Sonya, Park Chang, Jun Bai, Baden, Lindsey R, Walsh, Stephen R, Sherman, Amy C

المساهمون: National Institute of Allergy and Infectious Diseases, National Institutes of Health

المصدر: Open Forum Infectious Diseases ; volume 10, issue 7 ; ISSN 2328-8957

الاتاحة: http://dx.doi.org/10.1093/ofid/ofad349
https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofad349/50847279/ofad349.pdf
https://academic.oup.com/ofid/article-pdf/10/7/ofad349/50972764/ofad349.pdf

المؤلفون: Kovac, Victor, Goldberg, Hilary J, Kim, Andy J, Joyce, Mary-Ruth M, Mallidi, Hari R, Coppolino, Antonio, Townsend, Keri, Thaniyavarn, Tany, Kennedy, John C, Lee, Stefi F, Durney, Valerie, Liakos, Alexis, Harris, Courtney E, Little, Jessica S, Sherman, Amy C, Issa, Nicolas C, Baden, Lindsey R, Sharma, Nirmal S, Woolley, Ann E

المصدر: Open Forum Infectious Diseases ; volume 10, issue Supplement_2 ; ISSN 2328-8957

مصطلحات موضوعية: Infectious Diseases, Oncology

الاتاحة: http://dx.doi.org/10.1093/ofid/ofad500.2325
https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.2325/53757785/ofad500.2325.pdf

المؤلفون: Aleissa, Muneerah M, Davey, Sonya, Rooks, Rebecca, Izaguirre, Natalie E, Yates, Bridget, Kanwal, Urwah, Baden, Lindsey R, Issa, Nicolas C, Sherman, Amy C

المصدر: Open Forum Infectious Diseases ; volume 10, issue Supplement_2 ; ISSN 2328-8957

مصطلحات موضوعية: Infectious Diseases, Oncology

الاتاحة: http://dx.doi.org/10.1093/ofid/ofad500.1956
https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1956/53754527/ofad500.1956.pdf

المؤلفون: Harris, Courtney E, Kakoullis, Loukas, Aleissa, Muneerah M, Haddad, Esther Arbona, Kim, Andy J, Rooks, Rebecca, Yates, Bridget, Kanwal, Urwah, Izaguirre, Natalie E, Little, Jessica S, Hammond, Sarah P, Montgomery, Mary W, Sherman, Amy C, Maguire, James, Woolley, Ann E, Baden, Lindsey R, Issa, Nicolas C

المصدر: Open Forum Infectious Diseases ; volume 10, issue Supplement_2 ; ISSN 2328-8957

مصطلحات موضوعية: Infectious Diseases, Oncology

الاتاحة: http://dx.doi.org/10.1093/ofid/ofad500.2318
https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.2318/53757985/ofad500.2318.pdf

المؤلفون: Sherman, Amy C., Cheng, Chi-An, Swank, Zoe, Zhou, Guohai, Li, Xiaofang, Issa, Nicolas C., Walt, David R., Baden, Lindsey R., Soiffer, Robert J.

المصدر: Transplantation and Cellular Therapy ; volume 29, issue 5, page 337.e1-337.e5 ; ISSN 2666-6367

الاتاحة: http://dx.doi.org/10.1016/j.jtct.2023.01.025
https://api.elsevier.com/content/article/PII:S2666636723000623?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2666636723000623?httpAccept=text/plain

المؤلفون: Nanishi, Etsuro, Borriello, Francesco, O'Meara, Timothy R, McGrath, Marisa E, Saito, Yoshine, Haupt, Robert E, Seo, Hyuk-Soo, van Haren, Simon D, Cavazzoni, Cecilia B, Brook, Byron, Barman, Soumik, Chen, Jing, Diray-Arce, Joann, Doss-Gollin, Simon, De Leon, Maria, Prevost-Reilly, Alejandra, Chew, Katherine, Menon, Manisha, Song, Kijun, Xu, Andrew Z, Caradonna, Timothy M, Feldman, Jared, Hauser, Blake M, Schmidt, Aaron G, Sherman, Amy C, Baden, Lindsey R, Ernst, Robert K, Dillen, Carly, Weston, Stuart M, Johnson, Robert M, Hammond, Holly L, Mayer, Romana, Burke, Allen, Bottazzi, Maria E, Hotez, Peter J, Strych, Ulrich, Chang, Aiquan, Yu, Jingyou, Sage, Peter T, Barouch, Dan H, Dhe-Paganon, Sirano, Zanoni, Ivan, Ozonoff, Al, Frieman, Matthew B, Levy, Ofer, Dowling, David J

المصدر: Science translational medicine ; 14 ; 629 ; eabj5305 ; United States

Relation: Science Translational Medicine; http://hdl.handle.net/10713/17909

الاتاحة: http://hdl.handle.net/10713/17909
https://doi.org/10.1126/scitranslmed.abj5305

المؤلفون: Sherman, Amy C, Crombie, Jennifer L, Cheng, ChiAn, Desjardins, Michaël, Zhou, Guohai, Ometoruwa, Omolola, Rooks, Rebecca, Senussi, Yasmeen, McDonough, Mikaela, Guerrero, Liliana I, Kupelian, John, Doss-Gollin, Simon, Smolen, Kinga K, van Haren, Simon D, Armand, Philippe, Levy, Ofer, Walt, David R, Baden, Lindsey R, Issa, Nicolas C

المساهمون: Barbara and Amos Hostetter, Chleck Foundation, Harvard Clinical and Translational Science Center, National Center for Advancing Translational Science, Massachusetts Coalition for Pathogen Readiness, Harvard Medical School, Boston Children’s Hospital Department of Pediatrics, Boston Investment Council, Barry family

المصدر: Open Forum Infectious Diseases ; volume 9, issue 8 ; ISSN 2328-8957

الاتاحة: http://dx.doi.org/10.1093/ofid/ofac417
https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofac417/45433921/ofac417.pdf
https://academic.oup.com/ofid/article-pdf/9/8/ofac417/45612097/ofac417.pdf

المؤلفون: Gonzalez-Bocco, Isabel H, Cheng, Matthew, Aleissa, Muneerah M, Arbona, Esther I, Chen, Kaiwen, Zhou, Eric, Beluch, Katherine, Cho, Alyssa, Burchett, Sandra, Hammond, Sarah P, Issa, Nicolas C, Sherman, Amy C, Marty, Francisco M

المصدر: Open Forum Infectious Diseases ; volume 9, issue Supplement_2 ; ISSN 2328-8957

مصطلحات موضوعية: Infectious Diseases, Oncology

الاتاحة: http://dx.doi.org/10.1093/ofid/ofac492.024
https://academic.oup.com/ofid/article-pdf/9/Supplement_2/ofac492.024/47889523/ofac492.024.pdf

المؤلفون: Kokogho, Afoke, Aleissa, Muneerah M, Chang, Jun Bai Park, Walsh, Stephen R, Crowell, Trevor A, Baden, Lindsey R, Sherman, Amy C

المصدر: Open Forum Infectious Diseases ; volume 9, issue Supplement_2 ; ISSN 2328-8957

مصطلحات موضوعية: Infectious Diseases, Oncology

الاتاحة: http://dx.doi.org/10.1093/ofid/ofac492.914
https://academic.oup.com/ofid/article-pdf/9/Supplement_2/ofac492.914/47891712/ofac492.914.pdf