المؤلفون: Bertrand, F E, Steelman, L S, Chappell, W H, Abrams, S L, Shelton, J G, White, E R, Ludwig, D L, McCubrey, J A

المصدر: Leukemia ; volume 20, issue 7, page 1254-1260 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2404217
https://www.nature.com/articles/2404217.pdf
https://www.nature.com/articles/2404217

المؤلفون: Steelman, L S, Pohnert, S C, Shelton, J G, Franklin, R A, Bertrand, F E, McCubrey, J A

المصدر: Leukemia ; volume 18, issue 2, page 189-218 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2403241
https://www.nature.com/articles/2403241.pdf
https://www.nature.com/articles/2403241

المؤلفون: Bertrand, F E, Spengemen, J D, Shelton, J G, McCubrey, J A

المصدر: Leukemia ; volume 19, issue 1, page 98-102 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2403560
https://www.nature.com/articles/2403560.pdf
https://www.nature.com/articles/2403560

المؤلفون: Hamden, K E, Whitman, A G, Ford, P W, Shelton, J G, McCubrey, J A, Akula, S M

المصدر: Leukemia ; volume 19, issue 1, page 18-26 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2403532
https://www.nature.com/articles/2403532.pdf
https://www.nature.com/articles/2403532

المؤلفون: Chang, F, Steelman, L S, Lee, J T, Shelton, J G, Navolanic, P M, Blalock, W L, Franklin, R A, McCubrey, J A

المصدر: Leukemia ; volume 17, issue 7, page 1263-1293 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2402945
https://www.nature.com/articles/2402945.pdf
https://www.nature.com/articles/2402945

المؤلفون: Blalock, W L, Navolanic, P M, Steelman, L S, Shelton, J G, Moye, P W, Lee, J T, Franklin, R A, Mirza, A, McMahon, M, White, M K, McCubrey, J A

المصدر: Leukemia ; volume 17, issue 6, page 1058-1067 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2402925
https://www.nature.com/articles/2402925.pdf
https://www.nature.com/articles/2402925

المؤلفون: Chang, F, Lee, J T, Navolanic, P M, Steelman, L S, Shelton, J G, Blalock, W L, Franklin, R A, McCubrey, J A

المصدر: Leukemia ; volume 17, issue 3, page 590-603 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2402824
https://www.nature.com/articles/2402824.pdf
https://www.nature.com/articles/2402824

المؤلفون: Shelton, J G, Moye, P W, Steelman, L S, Blalock, W L, Lee, J T, Franklin, R A, McMahon, M, McCubrey, J A

المصدر: Leukemia ; volume 17, issue 9, page 1765-1782 ; ISSN 0887-6924 1476-5551

الاتاحة: http://dx.doi.org/10.1038/sj.leu.2403052
https://www.nature.com/articles/2403052.pdf
https://www.nature.com/articles/2403052

المؤلفون: Cromm, Philipp M., Crews, Craig M., Mainolfi, Nello, Rasmusson, Tim, Poulikakos, Poulikos I., Zhang, Chao, Bollag, Gideon, Shokat, Kevan M., Rosen, Neal, Agianian, Bogos, Gavathiotis, Evripidis, Raina, Kanak, Durrant, David E., Morrison, Deborah K., Neklesa, Taavi K., Winkler, James D., Chang, F., Steelman, L. S., Lee, J. T., Shelton, J. G., Navolanic, P. M., Blalock, W. L., Franklin, R. A., McCubrey, J. A., Burslem, George M., Smith, Blake E., Lai, Ashton C., Jaime-Figueroa, Saul, McQuaid, Daniel C., Bondeson, Daniel P., Toure, Momar, Dong, Hanqing, Qian, Yimin, Wang, Jing, Crew, Andrew P., Hines, John, Sanchez, Jaquelyn N., Wang, Ton, Cohen, Mark S., Shelledy, PharmD, Lindsay, Roman, PharmD, BCOP, Danielle, Davies, Helen, Bignell, Graham R., Cox, Charles, Stephens, Philip, Edkins, Sarah, Clegg, Sheila, Teague, Jon, Woffendin, Hayley, Garnett, Mathew J., Bottomley, William, Davis, Neil, Dicks, Ed, Ewing, Rebecca, Floyd, Yvonne, Gray, Kristian, Hall, Sarah, Hawes, Rachel, Hughes, Jaime, Kosmidou, Vivian, Menzies, Andrew, Mould, Catherine, Parker, Adrian, Stevens, Claire, Watt, Stephen, Hooper, Steven, Jayatilake, Hiran, Gusterson, Barry A., Cooper, Colin, Shipley, Janet, Hargrave, Darren, Pritchard-Jones, Katherine, Maitland, Norman, Chenevix-Trench, Georgia, Riggins, Gregory J., Bigner, Darell D., Palmieri, Giuseppe, Cossu, Antonio, Flanagan, Adrienne, Nicholson, Andrew, Ho, Judy W.C., Leung, Suet Y., Yuen, Siu T., Weber, Barbara L., Seigler, Hilliard F., Darrow, Timothy L., Paterson, Hugh, Wooster, Richard, Stratton, Michael R., Futreal, P. Andrew, Spevak, Wayne, Zhang, Ying, Burton, Elizabeth A., Ma, Yan, Habets, Gaston, Zhang, Jiazhong, Lin, Jack, Ewing, Todd, Matusow, Bernice, Tsang, Garson, Marimuthu, Adhirai, Cho, Hanna, Wu, Guoxian, Wang, Weiru, Fong, Daniel, Nguyen, Hoa, Shi, Songyuan, Womack, Patrick, Nespi, Marika, Shellooe, Rafe, Carias, Heidi, Powell, Ben, Light, Emily, Sanftner, Laura, Walters, Jason, Tsai, James, West, Brian L., Visor, Gary, Rezaei, Hamid, Lin, Paul S., Nolop, Keith, Ibrahim, Prabha N., Hirth, Peter, Arozarena, Imanol, Wellbrock, Claudia, Samatar, Ahmed A., Karoulia, Zoi, Chapman, Paul B., Hauschild, Axel, Robert, Caroline, Haanen, John B., Ascierto, Paolo, Larkin, James, Dummer, Reinhard, Garbe, Claus, Testori, Alessandro, Maio, Michele, Hogg, David, Lorigan, Paul, Lebbe, Celeste, Jouary, Thomas, Schadendorf, Dirk, Ribas, Antoni, O'Day, Steven J., Sosman, Jeffrey A., Kirkwood, John M., Eggermont, Alexander M.M., Dreno, Brigitte, Li, Jiang, Nelson, Betty, Hou, Jeannie, Lee, Richard J., Flaherty, Keith T., McArthur, Grant A., Vogelstein, Bert, Papadopoulos, Nickolas, Velculescu, Victor E., Zhou, Shibin, Diaz, Luis A., Kinzler, Kenneth W., Millington, G. W.M., Buhimschi, Alexandru D., Hamman, Brian D., Ishchenko, Alexey

المصدر: Cromm, P M, Crews, C M, Mainolfi, N, Rasmusson, T, Poulikakos, P I, Zhang, C, Bollag, G, Shokat, K M, Rosen, N, Crews, C M, Agianian, B, Gavathiotis, E, Raina, K, Crews, C M, Durrant, D E, Morrison, D K, Neklesa, T K, Winkler, J D, Crews, C M, Chang, F, Steelman, L S, Lee, J T, Shelton, J G, Navolanic, P M, Blalock, W L, Franklin, R A, McCubrey, J A, Burslem, G M, Smith, B E, Lai, A C, Jaime-Figueroa, S, McQuaid, D C, Bondeson, D P, Toure, M, Dong, H, Qian, Y, Wang, J, Crew, A P, Hines, J, Crews, C M, Sanchez, J N, Wang, T, Cohen, M S, Shelledy, PharmD, L, Roman, PharmD, BCOP, D, Davies, H, Bignell, G R, Cox, C, Stephens, P, Edkins, S, Clegg, S, Teague, J, Woffendin, H, Garnett, M J, Bottomley, W, Davis, N, Dicks, E, Ewing, R, Floyd, Y, Gray, K, Hall, S, Hawes, R, Hughes, J, Kosmidou, V, Menzies, A, Mould, C, Parker, A, Stevens, C, Watt, S, Hooper, S, Jayatilake, H, Gusterson, B A, Cooper, C, Shipley, J, Hargrave, D, Pritchard-Jones, K, Maitland, N, Chenevix-Trench, G, Riggins, G J, Bigner, D D, Palmieri, G, Cossu, A, Flanagan, A, Nicholson, A, Ho, J W C, Leung, S Y, Yuen, S T, Weber, B L, Seigler, H F, Darrow, T L, Paterson, H, Wooster, R, Wooster, R, Stratton, M R, Futreal, P A, Zhang, C, Spevak, W, Zhang, Y, Burton, E A, Ma, Y, Habets, G, Zhang, J, Lin, J, Ewing, T, Matusow, B, Tsang, G, Marimuthu, A, Cho, H, Wu, G, Wang, W, Fong, D, Nguyen, H, Shi, S, Womack, P, Nespi, M, Shellooe, R, Carias, H, Powell, B, Light, E, Sanftner, L, Walters, J, Tsai, J, West, B L, Visor, G, Rezaei, H, Lin, P S, Nolop, K, Ibrahim, P N, Hirth, P, Bollag, G, Arozarena, I, Wellbrock, C, Samatar, A A, Poulikakos, P I, Karoulia, Z, Gavathiotis, E, Poulikakos, P I, Chapman, P B, Hauschild, A, Robert, C, Haanen, J B, Ascierto, P, Larkin, J, Dummer, R, Garbe, C, Testori, A, Maio, M, Hogg, D, Lorigan, P, Lebbe, C, Jouary, T, Schadendorf, D, Ribas, A, O'Day, S J, Sosman, J A, Kirkwood, J M, Eggermont, A M M, Dreno, B, Nolop, K, Li, J, Nelson, B, Hou, J, Lee, R J, Flaherty, K T, McArthur, G A, Vogelstein, B, Papadopoulos, N, Velculescu, V E, Zhou, S, Diaz, L A, Kinzler, K W, Millington, G W M, Bondeson, D P, Smith, B E, Burslem, G M, Buhimschi, A D, Hines, J, Jaime-Figueroa, S, Wang, J, Hamman, B D, Ishchenko, A & Crews, C M 2018, ' The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study ', Cell Chemical Biology, pp. 67-77.e3 . https://doi.org/10.1016/j.chembiol.2017.09.009

مصطلحات موضوعية: 0301 basic medicine, Small molecular weight membrane-permeable inhibito, MAPK/p38, selective degradation, Raf kinases, Clinical Biochemistry, Receptor Protein-Tyrosine Kinases, protein-protein interactions, Signal transduction, Ligands, ERK cascade, protein dimerisation, Biochemistry, ternary complex, Receptor tyrosine kinase, Therapeutic intervention, 0302 clinical medicine, PROTACs, Drug Discovery, Kinome, Enzyme Inhibitors, Cereblon, E3 ligase, SNIPER, receptor tyrosine kinases, Manchester Cancer Research Centre, biology, Ras pathway, targeted degradation, Ubiquitin ligase, Raf inhibitors, 030220 oncology & carcinogenesis, Cytokines, cancer therapy, Molecular Medicine, Protein family, Ubiquitin-Protein Ligases, EGFR, hydrophobic tagging, Undruggable proteome, chemical biology, Protein degradation, Article, PROTAC, 03 medical and health sciences, proteomics, HER2, VHL, Humans, Molecular Biology, c-Met, Pharmacology, Heterobifunctional degrader, ResearchInstitutes_Networks_Beacons/mcrc, Proteolysis targeting chimera, Ubiquitination, Oncogenes, 030104 developmental biology, MAPK kinase cascade, CRBN, Proteolysis, biology.protein, Targeted protein degradation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361df2b1e3e643d7e80d0d128cb88ce3
https://doi.org/10.1016/j.chembiol.2017.09.009

المؤلفون: Hamden, K E, Whitman, A G, Ford, P W, Shelton, J G, McCubrey, J A, Akula, S M

المصدر: Leukemia (08876924); Jan2005, Vol. 19 Issue 1, p18-26, 9p, 2 Diagrams, 2 Charts

مصطلحات موضوعية: VASCULAR endothelial growth factors, KAPOSI'S sarcoma, NEOVASCULARIZATION, IMMUNOREGULATION, HERPESVIRUS diseases, CYTOKINES, CELLS, HERPESVIRUSES

المؤلفون: Bertrand, F E, Spengemen, J D, Shelton, J G, McCubrey, J A

المصدر: Leukemia (08876924); Jan2005, Vol. 19 Issue 1, p98-102, 5p

مصطلحات موضوعية: APOPTOSIS, CELLULAR mechanics, CELL death, BONE marrow, IMMUNE system, CELL culture, CELL lines, DNA synthesis

المؤلفون: Kiser, M, McCubrey, J A, Steelman, L S, Shelton, J G, Ramage, J, Alexander, R L, Kucera, G L, Pettenati, M, Willingham, M C, Miller, M S, Frankel, A E

المصدر: Leukemia (08876924); May2001, Vol. 15 Issue 5, p814-818, 5p

مصطلحات موضوعية: MYELOID leukemia, ONCOGENES, INTERLEUKINS

المؤلفون: Weinstein-Oppenheimer, C, Steelman, L S, Algate, P A, Blalock, W L, Burrows, C, Hoyle, P E, Lee, J T, Moye, P W, Shelton, J G, Franklin, R, McCubrey, J A

المصدر: Leukemia (08876924); Nov2000, Vol. 14 Issue 11, p1921-1938, 18p

مصطلحات موضوعية: HEMATOPOIETIC system, INTEGRINS, APOPTOSIS

المؤلفون: Townsend, S. L., Mackay, E. V., Shelton, J. G., Krieger, Vera I., Campbell, Kate I.

المصدر: BJOG: An International Journal of Obstetrics & Gynaecology; 1961, Vol. 68 Issue 3, p382-399, 18p

المؤلفون: Shelton, J. G., Gulland, S., Nicolson, K., Kearse, K. P., Backstrom, B. Thomas

المصدر: Molecular Immunology; 2001, Vol. 38 Issue: 4 p259-265, 7p

المؤلفون: McCubrey, J. A., Steelman, L. S., Blalock, W. L., Lee, J. T., Moye, P. W., Chang, F., Pearce, M., Shelton, J. G., White, M. K., Franklin, R. A.

المصدر: Advances in Enzyme Regulation; 2001, Vol. 41 Issue: 1 p289-323, 35p

المؤلفون: Shelton, J. G.

المساهمون: Latimer, Truett

مصطلحات موضوعية: Social Life and Customs - Correspondence, Government and Law - Texas Laws and Regulations, Government and Law - Elected Officials - Representatives, Business, Economics and Finance - Medicine, legislation, HB 5, optometrists, Latimer, Truett, Shelton, J. G

جغرافية الموضوع: United States - Texas, Into Modern Times

Time: Into Modern Times, 1939-Present, 1953-02~

وصف الملف: [1] p.; Text

Relation: local-cont-no: HSUL_1-05-01-072; https://texashistory.unt.edu/ark:/67531/metapth1196197/; ark: ark:/67531/metapth1196197

الاتاحة: https://texashistory.unt.edu/ark:/67531/metapth1196197/

المؤلفون: Steelman, L. S., Blalock, W. L., Wang, X. Y., Moye, P. W., Lee, J. T., Shelton, J. G., Navolanic, P. M., Davis, J. M., Knapp, S. L., Franklin, R. A., White, M. K., James McCubrey

المصدر: Scopus-Elsevier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::053d696cb76471e0f50e9ffff678e975
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037256323&partnerID=MN8TOARS

المؤلفون: Chang, F., Steelman, L. S., Shelton, J. G., Lee, J. T., Navolanic, P. M., Blalock, W. L., Franklin, R., James McCubrey

المصدر: Scopus-Elsevier
ResearcherID

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5a2ecb7d4001aca5414dd663aeaac73c
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037806885&partnerID=MN8TOARS

المؤلفون: Steelman, L. S., Blalock, W. L., Wang, X. Y., Moye, P. W., Lee, J. T., Shelton, J. G., Navolanic, P. M., Davis, J. M., Knapp, S. L., Franklin, R. A., White, M. K., James McCubrey

المصدر: Scopus-Elsevier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4e2411c3298d2851bd99d8709a052386
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037255998&partnerID=MN8TOARS