المؤلفون: Yongfeng Fan, Jianlong Lou, Christina C. Tam, Weihua Wen, Fraser Conrad, Priscila Leal da Silva Alves, Luisa W. Cheng, Consuelo Garcia-Rodriguez, Shauna Farr-Jones, James D. Marks

المصدر: Toxins, Vol 15, Iss 5, p 316 (2023)

مصطلحات موضوعية: botulinum neurotoxin, oligoclonal antibodies, serotype G botulism, recombinant antibodies, antibody engineering, mouse neutralization assay, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/15/5/316; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/276c0b76216c46e0a1b5bb0297a8d1eb

المؤلفون: Yongfeng Fan, Zhengda Sun, Fraser Conrad, Weihua Wen, Lequn Zhao, Jianlong Lou, Yu Zhou, Shauna Farr-Jones, James D Marks

المصدر: PLoS ONE, Vol 17, Iss 9, p e0273512 (2022)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/7144f5bc7dae452e9022a675df09d5ef

المؤلفون: Natalia Sevillano, Evan M Green, Jörg Votteler, Dong Young Kim, Xuefeng Ren, Bei Yang, Xi Liu, André Luiz Lourenço, James H Hurley, Shauna Farr-Jones, John D Gross, Yifan Cheng, Charles S Craik

المصدر: PLoS ONE, Vol 16, Iss 5, p e0250318 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/9b4fb5433d13446b97a21331867264a4

المؤلفون: Consuelo Garcia-Rodriguez, Shude Yan, Isin N. Geren, Kristeene A. Knopp, Jianbo Dong, Zhengda Sun, Jianlong Lou, Fraser Conrad, Wei-Hua Wen, Shauna Farr-Jones, Theresa J. Smith, Jennifer L. Brown, Janet C. Skerry, Leonard A. Smith, James D. Marks

المصدر: Toxins, Vol 13, Iss 9, p 641 (2021)

مصطلحات موضوعية: botulinum neurotoxin, oligoclonal antibodies, serotype C botulism, serotype D botulism, recombinant antibodies, antibody engineering, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/13/9/641; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/a25047536f784a189fd6ca0fc69595fc

المؤلفون: Milan T. Tomic, Shauna Farr-Jones, Emily S. Syar, Nancy Niemuth, Dean Kobs, Michael J. Hackett, Yero Espinoza, Zacchary Martinez, Khanh Pham, Doris M. Snow, James D. Marks, Ronald R. Cobb

المصدر: Toxins, Vol 13, Iss 9, p 671 (2021)

مصطلحات موضوعية: botulinum neurotoxin, botulism, aerosol, monoclonal antibody (mAb), guinea pig inhalation model, oligoclonal antibody, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/13/9/671; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/afc6f9a7ac414c809cee02b1394deb17

المؤلفون: Doris M. Snow, Ronald R. Cobb, Juan Martinez, Isaac Finger-Baker, Laura Collins, Sara Terpening, Emily S. Syar, Nancy Niemuth, Dean Kobs, Roy Barnewall, Shauna Farr-Jones, James D. Marks, Milan T. Tomic

المصدر: Toxins, Vol 13, Iss 1, p 31 (2021)

مصطلحات موضوعية: botulinum neurotoxin, aerosol, monoclonal antibody, guinea pig inhalation model, oligoclonal antibody, botulism, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/13/1/31; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/f418db8c7f81479aaeacc484f74d01c3

المؤلفون: Mingxiang Li, Dennis Lee, Chidi R Obi, Joel K Freeberg, Shauna Farr-Jones, Milan T Tomic

المصدر: PLoS ONE, Vol 13, Iss 5, p e0197011 (2018)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5944936?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/177f16fd05a148df946f5fe7204ad200

المؤلفون: Efrat T. Harel, Penelope M. Drake, Robyn M. Barfield, Irene Lui, Shauna Farr-Jones, Laura Van’t Veer, Zev J. Gartner, Evan M. Green, André Luiz Lourenço, Yifan Cheng, Byron C. Hann, David Rabuka, Charles S. Craik

المصدر: Antibodies, Vol 8, Iss 4, p 54 (2019)

مصطلحات موضوعية: antibody-drug conjugate (adc), urokinase receptor (upar), targeted therapy, triple-negative breast cancer (tnbc), cleavable linker, non-cleavable linker, site-specific conjugations, monomethyl auristatin e (mmae), maytansinoid, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4468/8/4/54; https://doaj.org/toc/2073-4468

URL الوصول: https://doaj.org/article/7ba679cb5b3b4d9787ad97d8bf10cae8

المؤلفون: Yero Espinoza, David Wong, Ago Ahene, Kenneth Der, Zachary Martinez, John Pham, Ronald R. Cobb, Shauna Farr-Jones, James. D. Marks, Milan T. Tomic

المصدر: Toxins, Vol 11, Iss 6, p 345 (2019)

مصطلحات موضوعية: botulinum neurotoxin, pharmacokinetics, recombinant antibody, rat, oligoclonal antibody, anti-botulinum neurotoxin antibody, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/11/6/345; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/086a1b33951547fc8503f1a30d1a4591

المؤلفون: Milan T. Tomic, Yero Espinoza, Zachary Martinez, Khanh Pham, Ronald R. Cobb, Doris M. Snow, Christopher G. Earnhart, Traci Pals, Emily S. Syar, Nancy Niemuth, Dean J. Kobs, Shauna Farr-Jones, James D. Marks

المصدر: Toxins, Vol 11, Iss 4, p 208 (2019)

مصطلحات موضوعية: botulinum neurotoxin, aerosol, monoclonal antibody, guinea pig inhalation model, oligoclonal antibody, inhalational botulism, botulism, Medicine

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6651/11/4/208; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/b04e358af4e84978943d1cb454d2f44b

المؤلفون: Consuelo Garcia-Rodriguez, Ali Razai, Isin N. Geren, Jianlong Lou, Fraser Conrad, Wei-Hua Wen, Shauna Farr-Jones, Theresa J. Smith, Jennifer L. Brown, Janet C. Skerry, Leonard A. Smith, James D. Marks

المصدر: Toxins, Vol 10, Iss 3, p 105 (2018)

مصطلحات موضوعية: botulinum neurotoxin, oligoclonal antibodies, serotype E botulism, recombinant antibodies, antibody engineering, mouse neutralization assay, botulinum antitoxin, Medicine

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2072-6651/10/3/105; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/49f299afeb6e4e768559329a7626fa78

المؤلفون: Jianlong Lou, Weihua Wen, Fraser Conrad, Qi Meng, Jianbo Dong, Zhengda Sun, Consuelo Garcia-Rodriguez, Shauna Farr-Jones, Luisa W. Cheng, Thomas D. Henderson, Jennifer L. Brown, Theresa J. Smith, Leonard A. Smith, Anthony Cormier, James D. Marks

المصدر: Toxins, Vol 10, Iss 2, p 84 (2018)

مصطلحات موضوعية: bi-epitopic, tri-epitopic, multivalent antibody, recombinant monoclonal antibody, botulinum neurotoxin, antitoxin, botulism, mouse neutralization assay, negative-stain electron microscopy, kinetic-exclusion analysis, Medicine

وصف الملف: electronic resource

Relation: http://www.mdpi.com/2072-6651/10/2/84; https://doaj.org/toc/2072-6651

URL الوصول: https://doaj.org/article/bda61dc1667e434a82809f2a43e8daa6

المؤلفون: Natalia Sevillano (2584285), Evan M. Green (10798149), Jörg Votteler (252907), Dong Young Kim (109467), Xuefeng Ren (216214), Bei Yang (19550), Xi Liu (142824), André Luiz Lourenço (10798152), James H. Hurley (302261), Shauna Farr-Jones (5204264), John D. Gross (109491), Yifan Cheng (666651), Charles S. Craik (174573)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, binding affinities, antibody reagents, Select Fabs, pipeline approach, Vif-CBF -β-ELOB, curated antibodies, antibody generation, multi-protein complexes, screening pipeline, HIV-host complexes, stain electron microscopy, HIV-Fab complexes, low-resolution structures, AP 2-complex, phage display library, ELISA, HIV-host factor complexes Viral inf., perturb HIV-host protein, drug resistance, ESCRT-I, HIV host-factor proteins, K D values

Relation: https://figshare.com/articles/journal_contribution/Size_exclusion_chromatography_of_fab_1D1_alone_on_Sepharose_200_/14591823

الاتاحة: https://doi.org/10.1371/journal.pone.0250318.s001

المؤلفون: Natalia Sevillano (2584285), Evan M. Green (10798149), Jörg Votteler (252907), Dong Young Kim (109467), Xuefeng Ren (216214), Bei Yang (19550), Xi Liu (142824), André Luiz Lourenço (10798152), James H. Hurley (302261), Shauna Farr-Jones (5204264), John D. Gross (109491), Yifan Cheng (666651), Charles S. Craik (174573)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, binding affinities, antibody reagents, Select Fabs, pipeline approach, Vif-CBF -β-ELOB, curated antibodies, antibody generation, multi-protein complexes, screening pipeline, HIV-host complexes, stain electron microscopy, HIV-Fab complexes, low-resolution structures, AP 2-complex, phage display library, ELISA, HIV-host factor complexes Viral inf., perturb HIV-host protein, drug resistance, ESCRT-I, HIV host-factor proteins, K D values

Relation: https://figshare.com/articles/journal_contribution/Size_exclusion_chromatography_of_fabs_alone_and_with_ESCRT-I_hE1_/14591826

الاتاحة: https://doi.org/10.1371/journal.pone.0250318.s002

المؤلفون: Natalia Sevillano (2584285), Evan M. Green (10798149), Jörg Votteler (252907), Dong Young Kim (109467), Xuefeng Ren (216214), Bei Yang (19550), Xi Liu (142824), André Luiz Lourenço (10798152), James H. Hurley (302261), Shauna Farr-Jones (5204264), John D. Gross (109491), Yifan Cheng (666651), Charles S. Craik (174573)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, binding affinities, antibody reagents, Select Fabs, pipeline approach, Vif-CBF -β-ELOB, curated antibodies, antibody generation, multi-protein complexes, screening pipeline, HIV-host complexes, stain electron microscopy, HIV-Fab complexes, low-resolution structures, AP 2-complex, phage display library, ELISA, HIV-host factor complexes Viral inf., perturb HIV-host protein, drug resistance, ESCRT-I, HIV host-factor proteins, K D values

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/14591832

الاتاحة: https://doi.org/10.1371/journal.pone.0250318.s004

المؤلفون: Natalia Sevillano (2584285), Evan M. Green (10798149), Jörg Votteler (252907), Dong Young Kim (109467), Xuefeng Ren (216214), Bei Yang (19550), Xi Liu (142824), André Luiz Lourenço (10798152), James H. Hurley (302261), Shauna Farr-Jones (5204264), John D. Gross (109491), Yifan Cheng (666651), Charles S. Craik (174573)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, binding affinities, antibody reagents, Select Fabs, pipeline approach, Vif-CBF -β-ELOB, curated antibodies, antibody generation, multi-protein complexes, screening pipeline, HIV-host complexes, stain electron microscopy, HIV-Fab complexes, low-resolution structures, AP 2-complex, phage display library, ELISA, HIV-host factor complexes Viral inf., perturb HIV-host protein, drug resistance, ESCRT-I, HIV host-factor proteins, K D values

Relation: https://figshare.com/articles/journal_contribution/Summary_of_Fab_selections_/14591829

الاتاحة: https://doi.org/10.1371/journal.pone.0250318.s003

المؤلفون: John D. Gross, Natalia Sevillano, Dong Young Kim, André Luiz Lourenço, James H. Hurley, Xi Liu, Xuefeng Ren, Evan M. Green, Jörg Votteler, Bei Yang, Shauna Farr-Jones, Charles S. Craik, Yifan Cheng

المساهمون: Mantis, Nicholas J

المصدر: PloS one, vol 16, iss 5
PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0250318 (2021)

مصطلحات موضوعية: RNA viruses, Phage display, Physiology, HIV Infections, Protein complex assembly, Pathology and Laboratory Medicine, Virus Replication, Biochemistry, Negative Staining, Epitope, law.invention, Immunodeficiency Viruses, Phage Display, law, Immune Physiology, Medicine and Health Sciences, 2.1 Biological and endogenous factors, Aetiology, Enzyme-Linked Immunoassays, Host factor, Staining, Multidisciplinary, Immune System Proteins, biology, Chemistry, Recombinant Proteins, Molecular Biology Display Techniques, Infectious Diseases, 5.1 Pharmaceuticals, Medical Microbiology, Viral Pathogens, Viruses, Recombinant DNA, HIV/AIDS, Medicine, Development of treatments and therapeutic interventions, Antibody, Pathogens, Infection, Biotechnology, Research Article, Protein Binding, General Science & Technology, Science, Immunology, Computational biology, Research and Analysis Methods, Microbiology, ESCRT, Antibodies, Vaccine Related, Immunoglobulin Fab Fragments, Antigen, Retroviruses, Humans, Immunoassays, Molecular Biology Techniques, Microbial Pathogens, Molecular Biology, Molecular Biology Assays and Analysis Techniques, Endosomal Sorting Complexes Required for Transport, Prevention, Lentivirus, Organisms, Biology and Life Sciences, Proteins, HIV, Protein Complexes, Good Health and Well Being, Specimen Preparation and Treatment, Multiprotein Complexes, biology.protein, Immunologic Techniques, HIV-1, Immunization, Cloning

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49550d230f28a0858a40cd84c7e8cae
https://escholarship.org/uc/item/05j700fv

المؤلفون: Juan Daniel Martínez, Nancy A. Niemuth, Emily S Syar, Shauna Farr-Jones, Roy E. Barnewall, Milan T. Tomic, Ronald R. Cobb, Doris M Snow, Dean J. Kobs, Isaac Finger-Baker, Sara J Terpening, James D. Marks, Laura J. Collins

المصدر: Toxins
Toxins, vol 13, iss 1
Toxins, Vol 13, Iss 31, p 31 (2021)
Volume 13
Issue 1

مصطلحات موضوعية: Serotype, Male, Botulinum Toxins, aerosol, Health, Toxicology and Mutagenesis, lcsh:Medicine, Pharmacology, Toxicology, Monoclonal, Medicine, Botulism, guinea pig inhalation model, Neutralizing, 0303 health sciences, biology, Antibodies, Monoclonal, botulinum neurotoxin, Pharmacology and Pharmaceutical Sciences, Foodborne Illness, Botulinum toxin, Drug Combinations, Infectious Diseases, Antitoxin, Antibody, Drug, medicine.drug, Biotechnology, medicine.drug_class, Guinea Pigs, Monoclonal antibody, Serogroup, Antibodies, Article, Guinea pig, Dose-Response Relationship, Vaccine Related, Lethal Dose 50, 03 medical and health sciences, Rare Diseases, Intensive care, Biodefense, Animals, Humans, 030304 developmental biology, Dose-Response Relationship, Drug, botulism, 030306 microbiology, business.industry, Animal, Prevention, lcsh:R, medicine.disease, Antibodies, Neutralizing, Disease Models, Animal, Emerging Infectious Diseases, monoclonal antibody, Immunoglobulin G, Disease Models, biology.protein, Immunization, oligoclonal antibody, Biochemistry and Cell Biology, Antitoxins, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd35116ff386f67a9b956136b6e08dcd
https://pubmed.ncbi.nlm.nih.gov/33466411

المؤلفون: Natalia Sevillano (2584285), Evan M. Green (10798149), Jörg Votteler (252907), Dong Young Kim (109467), Xuefeng Ren (216214), Bei Yang (19550), Xi Liu (142824), André Luiz Lourenço (10798152), James H. Hurley (302261), Shauna Farr-Jones (5204264), John D. Gross (109491), Yifan Cheng (666651), Charles S. Craik (174573)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, binding affinities, antibody reagents, Select Fabs, pipeline approach, Vif-CBF -β-ELOB, curated antibodies, antibody generation, multi-protein complexes, screening pipeline, HIV-host complexes, stain electron microscopy, HIV-Fab complexes, low-resolution structures, AP 2-complex, phage display library, ELISA, HIV-host factor complexes Viral inf., perturb HIV-host protein, drug resistance, ESCRT-I, HIV host-factor proteins, K D values

Relation: https://figshare.com/articles/figure/Elution_profiles_of_VCBC_complexed_with_six_different_Fabs_/14591844

الاتاحة: https://doi.org/10.1371/journal.pone.0250318.g004

المؤلفون: Natalia Sevillano (2584285), Evan M. Green (10798149), Jörg Votteler (252907), Dong Young Kim (109467), Xuefeng Ren (216214), Bei Yang (19550), Xi Liu (142824), André Luiz Lourenço (10798152), James H. Hurley (302261), Shauna Farr-Jones (5204264), John D. Gross (109491), Yifan Cheng (666651), Charles S. Craik (174573)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Infectious Diseases, Chemical Sciences not elsewhere classified, binding affinities, antibody reagents, Select Fabs, pipeline approach, Vif-CBF -β-ELOB, curated antibodies, antibody generation, multi-protein complexes, screening pipeline, HIV-host complexes, stain electron microscopy, HIV-Fab complexes, low-resolution structures, AP 2-complex, phage display library, ELISA, HIV-host factor complexes Viral inf., perturb HIV-host protein, drug resistance, ESCRT-I, HIV host-factor proteins, K D values

Relation: https://figshare.com/articles/figure/Experimental_workflow_for_antibody_selection_/14591838

الاتاحة: https://doi.org/10.1371/journal.pone.0250318.g002