المؤلفون: Michael Wleklinski, Paige M. Carpenter, Kevin D. Dykstra, Anthony Donofrio, Timothy Nowak, Shane W. Krska, Ronald D. Ferguson

المصدر: SLAS Technology, Vol 29, Iss 2, Pp 100126- (2024)

مصطلحات موضوعية: HTE, Parallel purification, Automation, Parallel synthesis, Analytical, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2472630324000086; https://doaj.org/toc/2472-6303

URL الوصول: https://doaj.org/article/551f9a876fc040d694b69bd9e46488ad

المؤلفون: Adrian D. Matthews, Ellyn Peters, John S. Debenham, Qi Gao, Maya D. Nyamiaka, Jianping Pan, Li-Kang Zhang, Spencer D. Dreher, Shane W. Krska, Matthew S. Sigman, Mycah R. Uehling

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Sociology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, multiple time points, demonstrate broad generality, complex aryl halides, build statistical models, aryl halides promoted, consistent data sets, oxamate ligand system, improved reaction performance, data science synthesis, investigating ligand function, branched aryl amines, stage library synthesis, used miniaturized hte, ligand features, cu oxamate, branched amines, throughput experimentation, substrate scope, rapid production, provided insight

Relation: https://figshare.com/articles/journal_contribution/Cu_Oxamate-Promoted_Cross-Coupling_of_Branched_Amines_and_Complex_Aryl_Halides_Investigating_Ligand_Function_through_Data_Science/24749091

الاتاحة: https://doi.org/10.1021/acscatal.3c04566.s003
https://figshare.com/articles/journal_contribution/Cu_Oxamate-Promoted_Cross-Coupling_of_Branched_Amines_and_Complex_Aryl_Halides_Investigating_Ligand_Function_through_Data_Science/24749091

المؤلفون: Ryan P. King (1736821), Shane W. Krska (1339053), Stephen L. Buchwald (1307121)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Space Science, Chemical Sciences not elsewhere classified, OAC, Ligand Exchange Process, bond connections, cross-coupling reaction, Palladium Oxidative Addition Comple., cross-coupling transformations, dative ligand, ligand exchange protocol

Relation: https://figshare.com/articles/journal_contribution/A_Ligand_Exchange_Process_for_the_Diversification_of_Palladium_Oxidative_Addition_Complexes/15066894

الاتاحة: https://doi.org/10.1021/acs.orglett.1c02101.s001

المؤلفون: Si-Jie Chen (9015926), Dung L. Golden (9183004), Shane W. Krska (1339053), Shannon S. Stahl (1291731)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Inorganic Chemistry, Space Science, Chemical Sciences not elsewhere classified, complex molecule synthesis, >- site selectivity, preferred site controlled, achieves site, substrates bearing, n <, medicinal chemistry, important motifs, enabling application, drug discovery, catalytic additives, broad utility, ambident reactivity

Relation: https://figshare.com/articles/journal_contribution/Copper-Catalyzed_Cross-Coupling_of_Benzylic_C_H_Bonds_and_Azoles_with_Controlled_i_N_i_Site_Selectivity/16550519

الاتاحة: https://doi.org/10.1021/jacs.1c07117.s001

المؤلفون: Spencer D. Dreher (1317162), Shane W. Krska (1339053)

مصطلحات موضوعية: Sociology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, nanoscale chemistry approaches, chemistry Informer Libraries, nonstandardized test molecules, substrate, PCA, data generation workflow, method, synthesis, principle component analysis, 1536- well-plate nanoscale reaction., reaction conditions

Relation: https://figshare.com/articles/journal_contribution/Chemistry_Informer_Libraries_Conception_Early_Experience_and_Role_in_the_Future_of_Cheminformatics/14224032

الاتاحة: https://doi.org/10.1021/acs.accounts.0c00760.s001

المؤلفون: Kevin D. Dykstra (1738981), Eric Streckfuss (1367958), Min Liu (45756), Jian Liu (33711), Younong Yu (1398901), Ming Wang (172316), Joseph A. Kozlowski (1398850), Robert W. Myers (3010719), Alexei V. Buevich (1433287), Milana M. Maletic (9514661), Petr Vachal (1445962), Shane W. Krska (1339053)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Pharmacology, Inorganic Chemistry, Plant Biology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, histone deacetylase, testing, microgram scale, CAD, aerosol detection, material requirements, Microscale Workflow, HPLC, approach, workflow, library synthesis, chemistry techniques, HDAC Inhibitor Libraries, high-throughput experimentation, compound libraries

Relation: https://figshare.com/articles/journal_contribution/Synthesis_of_HDAC_Inhibitor_Libraries_via_Microscale_Workflow/13770448

الاتاحة: https://doi.org/10.1021/acsmedchemlett.0c00596.s001

المؤلفون: Wendy Cao, Johnathan C. Maza, Natalia Chernyak, John A. Flygare, Shane W. Krska, F. Dean Toste, Matthew B. Francis

المصدر: Bioconjugate Chemistry. 34:510-517

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7d5746bbfe8c171172c1eed58f7e5693
https://doi.org/10.1021/acs.bioconjchem.2c00576

المؤلفون: Rebecca T. Ruck, Neil A. Strotman, Shane W. Krska

المصدر: ACS Catalysis. 13:475-503

مصطلحات موضوعية: General Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::07bd7dced9e25c63f9c26a623fb19074
https://doi.org/10.1021/acscatal.2c05159

المؤلفون: Shane W. Krska, Sriram Tyagarajan, Deodial Guiadeen, Eric Streckfuss, Xiaolei Gao, Alexei V. Buevich, George Doss, Jian Liu, Petr Vachal

المصدر: Synlett. 33:1259-1265

مصطلحات موضوعية: Organic Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::93fa372b4b2a7b9f22bfd3c4fdcca4e7
https://doi.org/10.1055/s-0040-1719923

المؤلفون: Cesar N. Prieto Kullmer, Jacob A. Kautzky, Shane W. Krska, Timothy Nowak, Spencer D. Dreher, David W. C. MacMillan

المصدر: Science

مصطلحات موضوعية: Multidisciplinary, Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7dedbb311cdaed9d29c74bd68fb545
https://doi.org/10.1126/science.abn1885

المؤلفون: Shasha Li, Dmitri Pissarnitski, Timothy Nowak, Michael Wleklinski, Shane W. Krska

المصدر: ACS Catalysis. 12:3201-3210

مصطلحات موضوعية: General Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::170275bdc2c12a6fbd5946ffe8d11567
https://doi.org/10.1021/acscatal.1c05502

المؤلفون: Shishi Lin, Spencer D. Dreher, Michael K. Wismer, Ning Qi, Shane W. Krska, Donald V. Conway

المصدر: Reaction Chemistry & Engineering. 7:354-360

مصطلحات موضوعية: Fluid Flow and Transfer Processes, Materials science, Chemistry (miscellaneous), business.industry, Process Chemistry and Technology, High-throughput screening, Chemical Engineering (miscellaneous), Optoelectronics, business, Catalysis, Intensity (heat transfer)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::16020e6c46d5b6657646423d7bef5aa7
https://doi.org/10.1039/d1re00317h

المؤلفون: Si-Jie Chen, Cyndi Qixin He, May Kong, Jun Wang, Shishi Lin, Shane W. Krska, Shannon S. Stahl

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::624117bcc1b44e54a878e5911d649f92
https://doi.org/10.26434/chemrxiv-2022-p98xq

المؤلفون: Simon Berritt, Melodie Christensen, Magnus J. Johansson, Shane W. Krska, Stephen G. Newman, Jessica Sampson, Eric M. Simmons, Ying Wang, Neil A. Strotman

المصدر: ACS Symposium Series ISBN: 9780841297579

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e26ecbaa9ab79c6c65ee327dd320e8f3
https://doi.org/10.1021/bk-2022-1419.ch001

المؤلفون: Shannon S Stahl, Shane W Krska, Cyndi Q. He, Shishi Lin, Dung L. Golden, Huayou Hu, Si-Jie Chen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::054e69ae539e367988c4dc1d7c1b7711
https://doi.org/10.1021/scimeetings.2c00470

المؤلفون: Shannon S. Stahl, Si-Jie Chen, Shane W. Krska, Dung L. Golden

المصدر: J Am Chem Soc

مصطلحات موضوعية: Azoles, Sulfonamides, Molecular Structure, Drug discovery, Chemistry, Site selectivity, General Chemistry, Oxidants, Biochemistry, Combinatorial chemistry, Article, Catalysis, Coupling (electronics), Colloid and Surface Chemistry, Benzyl Compounds, Indans, Copper catalyzed, Molecule, Reactivity (chemistry), Selectivity, Oxidation-Reduction, Copper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72fcbefefbdf8286a4b8162be39c714
https://doi.org/10.1021/jacs.1c07117

المؤلفون: Ryan P. King, Stephen L. Buchwald, Shane W. Krska

المصدر: Org Lett

مصطلحات موضوعية: Molecular Structure, Chemistry, Ligand, Organic Chemistry, chemistry.chemical_element, Ligands, Biochemistry, Oxidative addition, Combinatorial chemistry, Article, Catalysis, Exchange protocol, Physical and Theoretical Chemistry, Oxidation-Reduction, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61a5d1b44219c58704cf54ef07f9aca
https://doi.org/10.1021/acs.orglett.1c02101

المؤلفون: Shannon S. Stahl, Sung-Eun Suh, Shane W. Krska, Leah E Nkulu, Shishi Lin

المصدر: Chemical Science

مصطلحات موضوعية: Trimethylsilyl, 010405 organic chemistry, Drug discovery, Ligand, General Chemistry, Oxazoline, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, Isocyanate, 0104 chemical sciences, chemistry.chemical_compound, Chemistry, chemistry, Reagent, Functional group, Amine gas treating

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753db7eb4ba588e7310a4c63a169a24e
http://europepmc.org/articles/PMC8336431

المؤلفون: Shannon S. Stahl, Aristidis Vasilopoulos, Shane W. Krska

المصدر: Science. 372:398-403

مصطلحات موضوعية: chemistry.chemical_compound, Multidisciplinary, chemistry, Hydrogen bond, Radical, Methyl radical, Reactivity (chemistry), Photochemistry, Peroxide, Bond cleavage, Methyl group, Homolysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::56f411112283bd0a1303f235d8e1ffc6
https://doi.org/10.1126/science.abh2623

المؤلفون: Spencer D. Dreher, Shane W. Krska

المصدر: Accounts of Chemical Research. 54:1586-1596

مصطلحات موضوعية: Scope (project management), 010405 organic chemistry, Test data generation, business.industry, Usability, General Medicine, General Chemistry, Space (commercial competition), 010402 general chemistry, 01 natural sciences, Data science, 0104 chemical sciences, Workflow, Cheminformatics, Relevance (information retrieval), Chemistry (relationship), business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a60e10bec65da84eb21319c184dd9e
https://doi.org/10.1021/acs.accounts.0c00760