المؤلفون: Claudia Neumann-Haefelin, Shakir Sarhan, Hans-Paul Juretschke, Juergen Kalisch, Petty Margaret, Joseph G Wettstein

المصدر: European Journal of Pharmacology. 474:53-62

مصطلحات موضوعية: Brain Infarction, Male, Injections, Subcutaneous, Ischemia, Receptors, N-Methyl-D-Aspartate, Brain Ischemia, Rats, Sprague-Dawley, Mice, Bolus (medicine), Quinoxalines, medicine.artery, Occlusion, Animals, Medicine, Rats, Wistar, Stroke, Pharmacology, Behavior, Animal, Dose-Response Relationship, Drug, Licostinel, business.industry, Brain, medicine.disease, Magnetic Resonance Imaging, Rats, Inbred F344, Rats, Disease Models, Animal, Neuroprotective Agents, medicine.anatomical_structure, Anesthesia, Injections, Intravenous, Reperfusion, Middle cerebral artery, business, Perfusion, Psychomotor Performance, Artery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4921cc437249f5d17fb2608f2b198e
https://doi.org/10.1016/s0014-2999(03)02002-8

المؤلفون: Kenneth I. Maynard, Shakir Sarhan, Joseph G. Wettstein

المصدر: Neuroscience Letters. 347:147-150

مصطلحات موضوعية: Brain Infarction, Male, Time Factors, Ischemia, Infarction, Quinoxalinedione, Pharmacology, Receptors, N-Methyl-D-Aspartate, chemistry.chemical_compound, Receptors, Glycine, Quinoxalines, Animals, Medicine, Stroke, Nicotinamide, business.industry, Cerebral infarction, General Neuroscience, Antagonist, Brain, Infarction, Middle Cerebral Artery, medicine.disease, Rats, Inbred F344, Rats, Neuroprotective Agents, chemistry, Anesthesia, Injections, Intravenous, NMDA receptor, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3100e31db9c95455081068c6b1c7fd
https://doi.org/10.1016/s0304-3940(03)00693-1

المؤلفون: Nikolaus Seiler, Christine Grauffel, B. Knödgen, Paula M. Moran, Shakir Sarhan, M van den Buuse, S. Gobaille, J. Elands

المصدر: Pharmacology Biochemistry and Behavior. 50:181-189

مصطلحات موضوعية: Male, Dyskinesia, Drug-Induced, medicine.medical_specialty, genetic structures, Clinical Biochemistry, Neurological disorder, Toxicology, Biochemistry, Vigabatrin, Rats, Sprague-Dawley, Eating, Behavioral Neuroscience, Internal medicine, Dopamine receptor D2, medicine, Haloperidol, Animals, gamma-Aminobutyric Acid, Biological Psychiatry, Pharmacology, Glutamate Decarboxylase, Receptors, Dopamine D2, business.industry, Body Weight, Dopamine antagonist, Brain, medicine.disease, Rats, Endocrinology, nervous system, Dyskinesia, 4-Aminobutyrate Transaminase, Toxicity, GABAergic, Anticonvulsants, Stereotyped Behavior, Sulpiride, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149fcec81ac61eed9f2af2205092178c
https://doi.org/10.1016/0091-3057(94)00282-n

المؤلفون: Shakir Sarhan, Guy Therrien, B. Knödgen, Nikolaus Seiler, Roger F. Butterworth

المصدر: Metabolic Brain Disease. 9:211-224

مصطلحات موضوعية: Male, Ornithine, medicine.medical_specialty, Ornithine aminotransferase, Portacaval, Portacaval shunt, Biology, Biochemistry, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Ammonia, Internal medicine, medicine, Animals, Amino Acids, Ornithine-Oxo-Acid Transaminase, Portacaval Shunt, Surgical, Reabsorption, Body Weight, Metabolic disorder, Portacaval anastomosis, Brain, Hyperammonemia, medicine.disease, Rats, Endocrinology, Liver, chemistry, Neurology (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8bd2472b11f71eb0dab58a2f651bc8
https://doi.org/10.1007/bf01991195

المؤلفون: Nikolaus Seiler, Shakir Sarhan, Bernd Knoedgen

المصدر: Metabolic Brain Disease. 9:67-79

مصطلحات موضوعية: Ornithine, medicine.medical_specialty, Ornithine aminotransferase, Acetates, Biochemistry, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Ammonia, Carnitine, Internal medicine, Citrulline, medicine, Animals, Amino Acids, Poisoning, Brain, Drug Synergism, Endocrinology, chemistry, Urea cycle, Toxicity, Urea, Ammonia poisoning, Drug Therapy, Combination, Female, Neurology (clinical), Ammonium acetate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e72810301900af9223ec4ebcb46c8db5
https://doi.org/10.1007/bf01996075

المؤلفون: Bernd Knoedgen, Nikolaus Seiler, Shakir Sarhan, Christine Grauffel, Guy Therrien

المصدر: Journal of Chromatography B: Biomedical Sciences and Applications. 653:87-91

مصطلحات موضوعية: Male, Orotic acid, Urinary system, Ornithine Carbamoyltransferase Deficiency Disease, Urine, Lipid Metabolism, Inborn Errors, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, Ornithine Carbamoyltransferase, medicine, Animals, Humans, Orotic Acid, Isocratic elution, Chromatography, Chemistry, General Chemistry, Ornithine, Chromatography, Ion Exchange, Rats, Quaternary Ammonium Compounds, Biochemistry, Female, Spectrophotometry, Ultraviolet, Quantitative analysis (chemistry), medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e274782d64a618d4a63df94c47ca9070
https://doi.org/10.1016/0378-4347(93)e0409-j

المؤلفون: Christine Grauffel, Shakir Sarhan, Nikolaus Seiler, B. Knödgen

المصدر: Neurochemical Research. 18:539-549

مصطلحات موضوعية: Male, Ornithine, medicine.medical_specialty, Ornithine aminotransferase, Encephalopathy, Motor Activity, Thioacetamide, Biochemistry, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Internal medicine, medicine, Citrulline, Animals, Urea, Amino Acids, gamma-Aminobutyric Acid, Behavior, Animal, Ornithine-Oxo-Acid Transaminase, biology, Brain, General Medicine, Hypothermia, medicine.disease, Endocrinology, Liver, chemistry, Enzyme inhibitor, Hepatic Encephalopathy, biology.protein, Liver function, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cee57b25d2225e6c1817fde0f0930fc
https://doi.org/10.1007/bf00967259

المؤلفون: Marcelin Sablone, Nikolaus Seiler, Bernd Knoedgen, Shakir Sarhan, Jean-Marie Hornsperger

المصدر: Pharmacology & Toxicology. 72:116-123

مصطلحات موضوعية: Ornithine, medicine.medical_specialty, N-Methylaspartate, 3-Mercaptopropionic Acid, Health, Toxicology and Mutagenesis, Ornithine aminotransferase, medicine.medical_treatment, Toxicology, Mice, chemistry.chemical_compound, Epilepsy, Ammonia, Glutamate-Ammonia Ligase, Methionine Sulfoximine, Internal medicine, Putrescine, medicine, Animals, Coma, Postural Balance, Brain Chemistry, Pharmacology, Electroshock, Ornithine-Oxo-Acid Transaminase, Chemistry, Glutamate receptor, Strychnine, medicine.disease, Anticonvulsant, Endocrinology, Pentylenetetrazole, NMDA receptor, Epilepsy, Generalized, Female, Dizocilpine Maleate, Dialysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea110c014662412459bea39d512e69c
https://doi.org/10.1111/j.1600-0773.1993.tb00301.x

المؤلفون: Nikolaus Seiler, Shakir Sarhan, B. Knödgen

المصدر: Pharmacology & Toxicology. 70:373-380

مصطلحات موضوعية: Male, Ornithine, medicine.medical_specialty, Health, Toxicology and Mutagenesis, Ornithine aminotransferase, Spermine, Hemorrhage, Pilot Projects, Thioacetamide, Toxicology, Mice, chemistry.chemical_compound, Ammonia, Internal medicine, medicine, Animals, Amino Acids, Pharmacology, Ornithine-Oxo-Acid Transaminase, biology, Liver Diseases, Poisoning, Biogenic Polyamines, Lethal dose, Spermidine, Endocrinology, chemistry, Enzyme inhibitor, Toxicity, biology.protein, Chemical and Drug Induced Liver Injury

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02f723e7e4fe9969cc9f04b3fec8b2b
https://doi.org/10.1111/j.1600-0773.1992.tb00490.x

المؤلفون: Patrick Casara, Nikolaus Seiler, Bernd Knödgen, Shakir Sarhan

المصدر: Neurochemical Research. 16:285-293

مصطلحات موضوعية: Male, Drug, Ratón, media_common.quotation_subject, medicine.medical_treatment, Pharmacology, Biochemistry, Vigabatrin, Mice, Cellular and Molecular Neuroscience, Epilepsy, Seizures, Oral administration, medicine, Animals, 3-Mercaptopropionic Acid, gamma-Aminobutyric Acid, ED50, media_common, Aminocaproates, biology, business.industry, Rats, Inbred Strains, General Medicine, medicine.disease, Rats, Kinetics, Anticonvulsant, Enzyme inhibitor, 4-Aminobutyrate Transaminase, Fatty Acids, Unsaturated, biology.protein, Pentylenetetrazole, Anticonvulsants, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135c3e45eef18f1b9db43ac66de832e4
https://doi.org/10.1007/bf00966092

المؤلفون: V. Qubmener, B. Knödgen, Nikolaus Seiler, Shakir Sarhan, J.-Ph. Mouunoux

المصدر: International Journal of Biochemistry. 23:617-626

مصطلحات موضوعية: Male, Programmed cell death, Erythrocytes, Spermidine, Ratón, Spermine, Biochemistry, Mice, chemistry.chemical_compound, Polyamines, Putrescine, medicine, Animals, biology, Catabolism, Rats, Inbred Strains, Molecular biology, Rats, Mice, Inbred C57BL, Kinetics, Red blood cell, medicine.anatomical_structure, chemistry, Enzyme inhibitor, biology.protein, Female, Polyamine oxidase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3bd5d32bc0656aeee9fe0cd6c92248
https://doi.org/10.1016/0020-711x(87)90057-7

المؤلفون: Janice M Hitchcock, Christine Grauffel, Joseph G Wettstein, Shakir Sarhan

المصدر: Peptides. 18(8)

مصطلحات موضوعية: Agonist, Male, medicine.medical_specialty, Physiology, medicine.drug_class, (+)-Naloxone, Catalepsy, Pharmacology, Motor Activity, Biochemistry, Body Temperature, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Endocrinology, Dopamine, Internal medicine, medicine, Animals, Receptors, Neurotensin, Amphetamine, Phencyclidine, Neurotensin, Pain Measurement, Analgesics, Chemistry, digestive, oral, and skin physiology, Dopaminergic, medicine.disease, nervous system, Oligopeptides, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Antipsychotic Agents

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172e5da20795a5a0dd5f3e8f8d1c2642
https://pubmed.ncbi.nlm.nih.gov/9396065

المؤلفون: Shakir Sarhan, Christian D. Muller, B. Knödgen, Nikolaus Seiler, G. Rebel, C.L. Atanassov

المصدر: Research in immunology. 145(4)

مصطلحات موضوعية: Immunology, Acid Phosphatase, Cathepsin D, Enzyme-Linked Immunosorbent Assay, Acetates, Cell Line, chemistry.chemical_compound, Ammonia, Mice, Phagocytosis, Alzheimer Disease, Lysosome, medicine, Animals, Humans, Secretion, biology, Interleukin-6, Tumor Necrosis Factor-alpha, beta-Glucosidase, Acid phosphatase, Flow Cytometry, Enzyme assay, Endocytosis, medicine.anatomical_structure, chemistry, Biochemistry, Cell culture, biology.protein, Cytokines, Microglia, Lysosomes, Ammonium acetate, Interleukin-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4be1fadf9c52a07c129be3e845e745
https://pubmed.ncbi.nlm.nih.gov/7824805

المؤلفون: G Daune-Anglard, Shakir Sarhan, Nikolaus Seiler, B. Knödgen, Christine Grauffel

المصدر: Journal of inherited metabolic disease. 17(6)

مصطلحات موضوعية: Male, Ornithine, medicine.medical_specialty, Orotic acid, Ornithine aminotransferase, Biology, Excretion, chemistry.chemical_compound, Mice, Ornithine Carbamoyltransferase, Ammonia, Internal medicine, Genetics, medicine, Citrulline, Animals, Amino Acids, Genetics (clinical), Orotic Acid, Behavior, Animal, Ornithine-Oxo-Acid Transaminase, Hyperammonemia, medicine.disease, Mice, Mutant Strains, Endocrinology, chemistry, Mutation, Female, Orotic aciduria, Metabolism, Inborn Errors, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b239eba416303179b4771aa3b69701
https://pubmed.ncbi.nlm.nih.gov/7707692

المؤلفون: Shakir Sarhan, Nikolaus Seiler

المصدر: Journal of Neuroscience Research. 4:399-421

مصطلحات موضوعية: Male, medicine.medical_treatment, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Glutamates, In vivo, Centrifugation, Density Gradient, medicine, Animals, Pyridoxal phosphate, 3-Mercaptopropionic Acid, gamma-Aminobutyric Acid, Aminocaproates, chemistry.chemical_classification, Aspartic Acid, Glutamate Decarboxylase, Chemistry, Valproic Acid, Brain cortex, Compartmentalization (fire protection), Amino acid, Subcellular distribution, Anticonvulsant, nervous system, Biochemistry, Aromatic-L-Amino-Acid Decarboxylases, Pyridoxal Phosphate, Anticonvulsants, Free nerve ending, Synaptosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4a8a6103bdd9501250acbbd3dfe85e
https://doi.org/10.1002/jnr.490040508

المؤلفون: Nikolaus Seiler, B. Knödgen, Shakir Sarhan, Fritz Gerhart

المصدر: International Journal of Biochemistry. 19:843-852

مصطلحات موضوعية: Biology, Biochemistry, Molecular biology, Ornithine decarboxylase, Spermidine, chemistry.chemical_compound, Transformation (genetics), medicine.anatomical_structure, chemistry, In vivo, Spermine synthase, Putrescine, medicine, biology.protein, Yolk sac, Polyamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::01b24ddc682aa18e492fad4f70e097b3
https://doi.org/10.1016/0020-711x(87)90244-8

المؤلفون: Nikolaus Seiler, Shakir Sarhan

المصدر: Neurochemistry International. 5:625-633

مصطلحات موضوعية: animal structures, Glutamate decarboxylase activity, Central nervous system, Glutamate decarboxylase, Glutamate receptor, Embryo, Cell Biology, Biology, Spermidine, Cellular and Molecular Neuroscience, chemistry.chemical_compound, medicine.anatomical_structure, nervous system, chemistry, Biochemistry, embryonic structures, medicine, Putrescine, NAD+ kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a84d3e64b8ea410145c54384405bfd2
https://doi.org/10.1016/0197-0186(83)90056-6

المؤلفون: Nikolaus Seiler, Shakir Sarhan, Gerd Bink, Jeffrey Grove

المصدر: Journal of Chromatography B: Biomedical Sciences and Applications. 162:561-572

مصطلحات موضوعية: Electrophoresis, Male, Aging, Fluorescamine, gamma-Aminobutyric acid, chemistry.chemical_compound, Glutamates, Aspartic acid, medicine, Animals, gamma-Aminobutyric Acid, Brain Chemistry, Aspartic Acid, Chromatography, Chemistry, Glutamate receptor, Brain, General Chemistry, Glutamic acid, Chromatography, Ion Exchange, Fluorescence, Rats, Staining, Biochemistry, Chromatography, Thin Layer, Subcellular Fractions, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30933ac456d60e060f8b006b6e746d85
https://doi.org/10.1016/s0378-4347(00)81835-6

المؤلفون: B. Knödgen, Fritz Gerhart, Shakir Sarhan, Nikolaus Seiler

المصدر: Journal of Cancer Research and Clinical Oncology. 114:71-80

مصطلحات موضوعية: Cancer Research, Eflornithine, Endogeny, Urine, Ornithine Decarboxylase, Ornithine decarboxylase, Mice, chemistry.chemical_compound, Biomarkers, Tumor, Polyamines, Putrescine, medicine, Animals, Oxidoreductases Acting on CH-NH Group Donors, Fluorine, General Medicine, Small intestine, medicine.anatomical_structure, Oncology, chemistry, Biochemistry, Polyamine, Polyamine oxidase, Half-Life, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3b2d14e1dd386af67f8cc7e7cb4f3f
https://doi.org/10.1007/bf00390488

المؤلفون: Nikolaus Seiler, Shakir Sarhan

المصدر: Naunyn-Schmiedeberg's Archives of Pharmacology. 326:49-57

مصطلحات موضوعية: Male, Taurine, Sesterterpenes, Sarcosine, medicine.medical_treatment, Glycine, Pharmacology, Bicuculline, Inhibitory postsynaptic potential, Vigabatrin, Mice, chemistry.chemical_compound, Gabaculine, medicine, Animals, Picrotoxin, Amino Acids, 3-Mercaptopropionic Acid, Glycine receptor, Aminocaproates, Brain Chemistry, Aminooxyacetic Acid, Drug Synergism, Rats, Inbred Strains, Strychnine, General Medicine, Aminooxyacetic acid, Rats, Anticonvulsant, chemistry, Biochemistry, Ethanolamines, 4-Aminobutyrate Transaminase, Pentylenetetrazole, Anticonvulsants

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e2b3f52735cf5b73d23ef4afe41312
https://doi.org/10.1007/bf00518778