المؤلفون: Spears, Meghan, Lee, Namgyu, Hwang, Sunyoung, Park, Sung, Carlisle, Anne, Li, Rui, Doshi, Mihir, Armando, Aaron, Gao, Jenny, Simin, Karl, Zhu, Lihua, Greer, Paul, Quehenberger, Oswald, Torres, Eduardo, Kim, Dohoon

المصدر: Cell Reports. 40(13)

مصطلحات موضوعية: CP: Cancer, CP: Metabolism, cancer metabolism, cancer therapy, endoplasmic reticulum, ketodihydrosphingosine reductase, serine palmitoyltransferase, Lipogenesis, Neoplasms, Oxidoreductases, Serine, Serine C-Palmitoyltransferase, Sphingolipids, Sphingosine

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/29v8t3q2

المؤلفون: Piccolo, Brian D, Graham, James L, Kang, Ping, Randolph, Christopher E, Shankar, Kartik, Yeruva, Laxmi, Fox, Renee, Robeson, Michael S, Moody, Becky, LeRoith, Tanya, Stanhope, Kimber L, Adams, Sean H, Havel, Peter J

المصدر: Physiological Reports. 9(22)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Nutrition, Colo-Rectal Cancer, Diabetes, Genetics, Human Genome, Cancer, Digestive Diseases, Akkermansia, Amino Acid Transport Systems, Neutral, Animals, Clostridiales, Colon, Diabetes Mellitus, Type 2, Disease Progression, Dysbiosis, Gastrointestinal Microbiome, Gene Expression Profiling, Ileum, Intestinal Mucosa, Potassium Channels, RNA, Ribosomal, 16S, Rats, Serine C-Palmitoyltransferase, Sphingomyelin Phosphodiesterase, Veillonellaceae, crypt, diabetes, microbiome, RNA-seq, UCD-T2DM rat, villi, Physiology, Clinical Sciences, Medical physiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8kw2p95q
https://escholarship.org/content/qt8kw2p95q/qt8kw2p95q.pdf

المؤلفون: GUISSART, Claire, DE LA CRUZ, Elisa, FLABEAU, Olivier, GRAPPERON, Aude-Marie, CORAZZA, Giovanni, JUNILHON, Lucie, DELMAS, Jean-Charles, MILLECAMPS, Stéphanie, POLGE, Anne, AMADOR, Maria Del Mar, SALACHAS, Francois, ROCHAT, Julie, GOIZET, Cyril, JUNTAS MORALES, Raul, LUMBROSO, Serge, PHILIBERT, Pascal, CHEILLAN, David, MOUZAT, Kevin

مصطلحات موضوعية: Humans, Amyotrophic Lateral Sclerosis, Mutation, Serine C-Palmitoyltransferase, Sciences du Vivant [q-bio]/Génétique

الاتاحة: https://oskar-bordeaux.fr/handle/20.500.12278/204057
https://hdl.handle.net/20.500.12278/204057
https://doi.org/10.1136/jnnp-2023-331753

المؤلفون: Muthusamy, Thangaselvam, Cordes, Thekla, Handzlik, Michal K, You, Le, Lim, Esther W, Gengatharan, Jivani, Pinto, Antonio FM, Badur, Mehmet G, Kolar, Matthew J, Wallace, Martina, Saghatelian, Alan, Metallo, Christian M

المصدر: Nature. 586(7831)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Nutrition, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Alanine, Animals, Cell Adhesion, Cell Division, Diet, Female, Glycine, HCT116 Cells, Humans, Membrane Lipids, Mice, Mitochondria, Neoplasms, Phosphoglycerate Dehydrogenase, Pyruvic Acid, Serine, Serine C-Palmitoyltransferase, Spheroids, Cellular, Sphingolipids, Stress, Physiological, Xenograft Model Antitumor Assays, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3rs223c0
https://escholarship.org/content/qt3rs223c0/qt3rs223c0.pdf

المؤلفون: Chen, Tzu-Chieh, Lee, Rebecca A, Tsai, Sam L, Kanamaluru, Deepthi, Gray, Nora E, Yiv, Nicholas, Cheang, Rachel T, Tan, Jenna H, Lee, Justin Y, Fitch, Mark D, Hellerstein, Marc K, Wang, Jen-Chywan

المصدر: Journal of Biological Chemistry. 294(23)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Genetics, Liver Disease, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Aetiology, 2.1 Biological and endogenous factors, Angiopoietin-Like Protein 4, Animals, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Ceramides, Dexamethasone, Fatty Acid Synthase, Type I, Fatty Acids, Monounsaturated, Fatty Liver, Hypertriglyceridemia, Lipogenesis, Liver, Male, Mice, Mice, Knockout, Protein Kinase C, Protein Phosphatase 2, RNA Interference, RNA, Small Interfering, Serine C-Palmitoyltransferase, Triglycerides, liver, glucocorticoid, ceramide, triglyceride, metabolic syndrome, steroid hormone, dyslipidemia, lipogenesis, fatty liver disease, hepatosteatosis, hypertriglyceridemia, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8f57n61m
https://escholarship.org/content/qt8f57n61m/qt8f57n61m.pdf

المؤلفون: Lallement, Justine, Raho, Ilyès, Merlen, Grégory, Rainteau, Dominique, Croyal, Mikael, Schiffano, Melody, Kassis, Nadim, Doignon, Isabelle, Soty, Maud, Lachkar, Floriane, Krempf, Michel, van Hul, Matthias, Cani, Patrice D., Foufelle, Fabienne, Amouyal, Chloé, Le Stunff, Hervé, Magnan, Christophe, Tordjmann, Thierry, Cruciani-Guglielmacci, Céline

المساهمون: Unité de Biologie Fonctionnelle et Adaptative (BFA (UMR_8251 / U1133)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Physiopathologie et traitement des maladies du foie, Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Microbiote, intestin et inflammation CRSA, Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), PHU 2 - Institut du Thorax et du Sytème Nerveux CHU Nantes (ITSN), Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Physiopathologie des Adaptations Nutritionnelles (PhAN), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Nutrition et cerveau (U1213, U855), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Clinique Bretéché, Groupe Elsan, Nantes, Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain = Catholic University of Louvain (UCL), Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), ANR-17-EURE-0013,GENE,Génétique et Epigénétique Nouvelle Ecole(2017), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018)

المصدر: ISSN: 1388-1981 ; Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids ; https://cnrs.hal.science/hal-04282229 ; Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2023, 1868 (8), pp.1-13. ⟨10.1016/j.bbalip.2023.159333⟩.

مصطلحات موضوعية: Bile acids, Ceramides, Fibrosis, Gluconeogenesis, Liver, Sphingomyelinase, MESH: Animals, MESH: Mice, MESH: Serine, MESH: Serine C-Palmitoyltransferase, MESH: Sphingolipids, MESH: Sphingomyelins, MESH: Bile Acids and Salts, MESH: Ceramides, MESH: Diabetes Mellitus, Type 2, MESH: Glucose, MESH: Homeostasis, MESH: Liver, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/37224999; PUBMED: 37224999; WOS: 001012679700001

الاتاحة: https://cnrs.hal.science/hal-04282229
https://cnrs.hal.science/hal-04282229v1/document
https://cnrs.hal.science/hal-04282229v1/file/2023_Lallement_BBA.pdf
https://doi.org/10.1016/j.bbalip.2023.159333

المؤلفون: Shahin, Mohamed H, Gong, Yan, Frye, Reginald F, Rotroff, Daniel M, Beitelshees, Amber L, Baillie, Rebecca A, Chapman, Arlene B, Gums, John G, Turner, Stephen T, Boerwinkle, Eric, Motsinger‐Reif, Alison, Fiehn, Oliver, Cooper‐DeHoff, Rhonda M, Han, Xianlin, Kaddurah‐Daouk, Rima, Johnson, Julie A

المصدر: Journal of the American Heart Association. 7(1)

مصطلحات موضوعية: Human Genome, Genetics, Hypertension, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Cardiovascular, Adult, Blood Pressure, Female, Genomics, Humans, Hydrochlorothiazide, Lipid Metabolism, Male, Metabolic Networks and Pathways, Metabolomics, Middle Aged, Nitriles, Pharmacogenetics, Prognosis, Serine C-Palmitoyltransferase, Siloxanes, Sodium Chloride Symporter Inhibitors, Sphingolipids, Treatment Outcome, blood pressure, lipid metabolites, metabolomics, pharmacogenetics, thiazide diuretics, Cardiorespiratory Medicine and Haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0z191365

المؤلفون: Realini, Natalia, Palese, Francesca, Pizzirani, Daniela, Pontis, Silvia, Basit, Abdul, Bach, Anders, Ganesan, Anand, Piomelli, Daniele

المصدر: Journal of Biological Chemistry. 291(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Cancer, 1.1 Normal biological development and functioning, Acid Ceramidase, Cell Line, Tumor, Cell Proliferation, Cell Survival, Ceramides, Down-Regulation, Enzyme Inhibitors, Fibroblasts, Gene Expression Regulation, Neoplastic, HCT116 Cells, Hep G2 Cells, Humans, Inhibitory Concentration 50, Keratinocytes, Lipids, Lysophospholipids, MCF-7 Cells, Melanocytes, Melanoma, Microscopy, Confocal, Microscopy, Fluorescence, Oxidoreductases, RNA, Small Interfering, Serine C-Palmitoyltransferase, Signal Transduction, Skin Neoplasms, Sphingolipids, Sphingosine, Uracil, acid ceramidase, cancer biology, ceramide, enzyme inhibitor, melanoma, sphingolipid, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2w355221
https://escholarship.org/content/qt2w355221/qt2w355221.pdf

المؤلفون: Cordes, Thekla, Kuna, Ramya S, McGregor, Grace H, Khare, Sanika V, Gengatharan, Jivani, Muthusamy, Thangaselvam, Metallo, Christian M

المصدر: Journal of lipid research 63 (2022) 10, 100281. - https://doi.org/10.1016/j.jlr.2022.100281 -- J Lipid Res -- 0022-2275 -- 1539-7262

مصطلحات موضوعية: Article, ddc:572, Veröffentlichung der TU Braunschweig, Publikationsfonds der TU Braunschweig, Cell Membrane, Neoplasms, Ceramides, Agar, Sphingolipids, Alanine, Serine, Endocytosis, Serine C-Palmitoyltransferase, Metabolic Networks and Pathways, Metabolism, Rab5, soft agar, Serine Palmitoyltransferase, Mitochondrial Stress, 1-Deoxy(dihydro)ceramide, 1-Deoxysphingolipid Accumulation, Spt Promiscuity

وصف الملف: 13 Seiten

Relation: https://doi.org/10.1016/j.jlr.2022.100281; https://nbn-resolving.org/urn:nbn:de:gbv:084-2022121513286; https://leopard.tu-braunschweig.de/receive/dbbs_mods_00071791; https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00050419/Cordes_PIIS0022227522001146.pdf; http://publikationsserver.tu-braunschweig.de/get/71791; http://www.jlr.org/article/S0022227522001146/pdf

الاتاحة: https://doi.org/10.1016/j.jlr.2022.100281
https://nbn-resolving.org/urn:nbn:de:gbv:084-2022121513286
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00071791
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00050419/Cordes_PIIS0022227522001146.pdf
http://publikationsserver.tu-braunschweig.de/get/71791
http://www.jlr.org/article/S0022227522001146/pdf

المؤلفون: Gonzaga-Jauregui, Claudia, Harel, Tamar, Gambin, Tomasz, Kousi, Maria, Griffin, Laurie, Francescatto, Ludmila, Ozes, Burcak, Karaca, Ender, Jhangiani, Shalini, Bainbridge, Matthew, Lawson, Kim, Pehlivan, Davut, Okamoto, Yuji, Withers, Marjorie, Mancias, Pedro, Slavotinek, Anne, Reitnauer, Pamela, Goksungur, Meryem, Shy, Michael, Crawford, Thomas, Koenig, Michel, Willer, Jason, Flores, Brittany, Pediaditrakis, Igor, Us, Onder, Wiszniewski, Wojciech, Parman, Yesim, Antonellis, Anthony, Muzny, Donna, Katsanis, Nicholas, Battaloglu, Esra, Boerwinkle, Eric, Gibbs, Richard, Lupski, James

المصدر: Cell Reports. 12(7)

مصطلحات موضوعية: Animals, Charcot-Marie-Tooth Disease, Exome, Female, Genetic Load, Genetic Variation, HSP40 Heat-Shock Proteins, Humans, Male, Mutation, Myelin P2 Protein, Pedigree, Penetrance, Peripheral Nervous System Diseases, Phenotype, Serine C-Palmitoyltransferase, Suppression, Genetic, Zebrafish

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0x9278hg
https://escholarship.org/content/qt0x9278hg/qt0x9278hg.pdf

المؤلفون: Samokhvalov, Victor, Zlobine, Igor, Jamieson, Kristi L, Jurasz, Paul, Chen, Christopher, Lee, Kin Sing Stephen, Hammock, Bruce D, Seubert, John M

المصدر: Toxicology Letters. 232(1)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Dietary Supplements, Complementary and Integrative Health, 1.1 Normal biological development and functioning, Generic health relevance, Activation, Metabolic, Animals, Apoptosis, Benzamides, Cardiotoxicity, Cell Line, Cell Survival, Ceramides, Cytochrome P-450 Enzyme System, Docosahexaenoic Acids, Energy Metabolism, Enzyme Inhibitors, Fatty Acids, Monounsaturated, Ligands, Myocytes, Cardiac, Oxidation-Reduction, PPAR delta, Rats, Serine C-Palmitoyltransferase, Signal Transduction, Sulfones, Time Factors, Docosahexaenoic acid, Epoxydocosapentaenoic acids, H9c2?cells, Ceramide, H9c2 cells, PPARδ, Environmental Science and Management, Toxicology, Pharmacology and pharmaceutical sciences, Pollution and contamination

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7cw569mb
https://escholarship.org/content/qt7cw569mb/qt7cw569mb.pdf

المؤلفون: Rochat, Julie, Blavier, André, Ruet, Séverine, Vasseur, Sophie, Puma, Angela, Desnous, Béatrice, Chan, Victor, Delmont, Emilien, Attarian, Shahram, Juntas Morales, Raul, Quadrio, Isabelle, Vidoni, Léo, Bonello-Palot, Nathalie, Cheillan, David

المساهمون: Radiopharmaceutical and Neurochemical Biomarkers (CRNL-BIORAN), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hospices Civils de Lyon (HCL)

المصدر: ISSN: 2073-4425 ; Genes ; https://hal.science/hal-04796410 ; Genes, 2024, 15 (6), pp.692. ⟨10.3390/genes15060692⟩.

مصطلحات موضوعية: SPTLC1, hereditary neuropathy, in silico tools, molecular genetics, sphingolipids, MESH: Humans, MESH: Serine C-Palmitoyltransferase, MESH: Hereditary Sensory and Autonomic Neuropathies, MESH: Mutation, Missense, MESH: Male, MESH: Female, MESH: Sphingolipids, MESH: Adult, MESH: Middle Aged, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.GEN]Life Sciences [q-bio]/Genetics

Relation: info:eu-repo/semantics/altIdentifier/pmid/38927628; PUBMED: 38927628; PUBMEDCENTRAL: PMC11203308

الاتاحة: https://hal.science/hal-04796410
https://doi.org/10.3390/genes15060692

المؤلفون: Johnson J. O., Chia R., Miller D. E., Li R., Kumaran R., Abramzon Y., Alahmady N., Renton A. E., Topp S. D., Gibbs J. R., Cookson M. R., Sabir M. S., Dalgard C. L., Troakes C., Jones A. R., Shatunov A., Iacoangeli A., Al Khleifat A., Ticozzi N., Silani V., Gellera C., Blair I. P., Dobson-Stone C., Kwok J. B., Bonkowski E. S., Palvadeau R., Tienari P. J., Morrison K. E., Shaw P. J., Al-Chalabi A., Brown R. H., Calvo A., Mora G., Al-Saif H., Gotkine M., Leigh F., Chang I. J., Perlman S. J., Glass I., Scott A. I., Shaw C. E., Basak A. N., Landers J. E., Chio A., Crawford T. O., Smith B. N., Traynor B. J., Fallini C., Gkazi A. S., Scotter E. L., Kenna K. P., Keagle P., Tiloca C., Vance C., Colombrita C., King A., Pensato V., Castellotti B., Baas F., Ten Asbroek A. L. M. A., McKenna-Yasek D., McLaughlin R. L., Polak M., Asress S., Esteban-Perez J., Stevic Z., D'Alfonso S., Mazzini L., Comi G. P., Del Bo R., Ceroni M., Gagliardi S., Querin G., Bertolin C., Van Rheenen W., Rademakers R., Van Blitterswijk M., Lauria G., Duga S., Corti S., Cereda C., Corrado L., Soraru G., Williams K. L., Nicholson G. A., Leblond-Manry C., Rouleau G. A., Hardiman O., Veldink J. H., Van Den Berg L. H., Pall H., Turner M. R., Talbot K., Taroni F., Garcia-Redondo A., Wu Z., Glass J. D., Ratti A., Adeleye A., Soltis A. R., Alba C., Viollet C., Bacikova D., Hupalo D. N., Sukumar G., Pollard H. B., Wilkerson M. D., Martinez E. M., Ahmed S., Arepalli S., Baloh R. H., Bowser R., Brady C. B., Brice A., Broach J., Campbell R. H., Camu W., Cooper-Knock J., Ding J., Drepper C., Drory V. E., Dunckley T. L., Eicher J. D., England B. K., Faghri F., Feldman E., Floeter M. K., Fratta P., Geiger J. T., Gerhard G., Gibson S. B., Hardy J., Harms M. B., Heiman-Patterson T. D., Hernandez D. G., Jansson L., Kirby J., Kowall N. W., Laaksovirta H., Landeck N., Landi F., Le Ber I., Lumbroso S., Macgowan D. J. L., Maragakis N. J., Mouzat K., Murphy N. A., Myllykangas L., Nalls M. A., Orrell R. W., Ostrow L. W., Pamphlett R., Pickering-Brown S., Pioro E. P., Pletnikova O., Pliner H. A., Pulst S. M., Ravits J. M., Rivera A., Robberecht W., Rogaeva E., Rollinson S., Rothstein J. D., Scholz S. W., Sendtner M., Sidle K. C., Simmons Z., Singleton A. B., Smith N., Stone D. J., Troncoso J. C., Valori M., Van Damme P., Van Deerlin V. M., Van Den Bosch L., Zinman L., Angelocola S. M., Ausiello F. P., Barberis M., Bartolomei I., Battistini S., Bersano E., Bisogni G., Borghero G., Brunetti M., Cabona C., Canale F., Canosa A., Cantisani T. A., Capasso M., Caponnetto C., Cardinali P., Carrera P., Casale F., Colletti T., Conforti F. L., Conte A., Conti E., Corbo M., Cuccu S., Dalla Bella E., D'Errico E., Demarco G., Dubbioso R., Ferrarese C., Ferraro P. M., Filippi M., Fini N., Floris G., Fuda G., Gallone S., Gianferrari G., Giannini F., Grassano M., Greco L., Iazzolino B., Introna A., La Bella V., Lattante S., Liguori R., Logroscino G., Logullo F. O., Lunetta C., Mandich P., Mandrioli J., Manera U., Manganelli F., Marangi G., Marinou K., Marrosu M. G., Martinelli I., Messina S., Moglia C., Mosca L., Murru M. R., Origone P., Passaniti C., Petrelli C., Petrucci A., Pozzi S., Pugliatti M., Quattrini A., Ricci C., Riolo G., Riva N., Russo M., Sabatelli M., Salamone P., Salivetto M., Salvi F., Santarelli M., Sbaiz L., Sideri R., Simone I., Simonini C., Spataro R., Tanel R., Tedeschi G., Ticca A., Torriello A., Tranquilli S., Tremolizzo L., Trojsi F., Vasta R., Vacchiano V., Vita G., Volanti P., Zollino M., Zucchi E.

المساهمون: Johnson, J. O., Chia, R., Miller, D. E., Li, R., Kumaran, R., Abramzon, Y., Alahmady, N., Renton, A. E., Topp, S. D., Gibbs, J. R., Cookson, M. R., Sabir, M. S., Dalgard, C. L., Troakes, C., Jones, A. R., Shatunov, A., Iacoangeli, A., Al Khleifat, A., Ticozzi, N., Silani, V., Gellera, C., Blair, I. P., Dobson-Stone, C., Kwok, J. B., Bonkowski, E. S., Palvadeau, R., Tienari, P. J., Morrison, K. E., Shaw, P. J., Al-Chalabi, A., Brown, R. H., Calvo, A., Mora, G., Al-Saif, H., Gotkine, M., Leigh, F., Chang, I. J., Perlman, S. J., Glass, I., Scott, A. I., Shaw, C. E., Basak, A. N., Landers, J. E., Chio, A., Crawford, T. O., Smith, B. N., Traynor, B. J., Fallini, C., Gkazi, A. S., Scotter, E. L., Kenna, K. P., Keagle, P., Tiloca, C., Vance, C., Colombrita, C., King, A., Pensato, V., Castellotti, B., Baas, F., Ten Asbroek, A. L. M. A., McKenna-Yasek, D., Mclaughlin, R. L., Polak, M., Asress, S., Esteban-Perez, J., Stevic, Z., D'Alfonso, S., Mazzini, L., Comi, G. P., Del Bo, R., Ceroni, M., Gagliardi, S., Querin, G., Bertolin, C., Van Rheenen, W., Rademakers, R., Van Blitterswijk, M., Lauria, G., Duga, S., Corti, S., Cereda, C., Corrado, L., Soraru, G., Williams, K. L., Nicholson, G. A., Leblond-Manry, C., Rouleau, G. A., Hardiman, O., Veldink, J. H., Van Den Berg, L. H., Pall, H., Turner, M. R.

مصطلحات موضوعية: Adolescent, Adult, Amyotrophic Lateral Sclerosi, Child, Preschool, Female, Genetic Predisposition to Disease, Human, Mutation, Serine C-Palmitoyltransferase, Whole Exome Sequencing, Young Adult

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/34459874; info:eu-repo/semantics/altIdentifier/wos/WOS:000692566100005; volume:78; issue:10; firstpage:1236; lastpage:1248; numberofpages:13; journal:JAMA NEUROLOGY; http://hdl.handle.net/11365/1181203; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85114289450; https://jamanetwork.com/journals/jamaneurology/fullarticle/2783665; https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8406220/

الاتاحة: http://hdl.handle.net/11365/1181203
https://doi.org/10.1001/jamaneurol.2021.2598
https://jamanetwork.com/journals/jamaneurology/fullarticle/2783665
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8406220/

المؤلفون: Breslow, David K, Collins, Sean R, Bodenmiller, Bernd, Aebersold, Ruedi, Simons, Kai, Shevchenko, Andrej, Ejsing, Christer S, Weissman, Jonathan S

المصدر: Nature. 463(7284)

مصطلحات موضوعية: Cell Line, Hela Cells, Humans, Saccharomyces cerevisiae, Asthma, Multiprotein Complexes, Phosphoric Monoester Hydrolases, Fatty Acids, Monounsaturated, Sphingolipids, Saccharomyces cerevisiae Proteins, Amino Acid Sequence, Conserved Sequence, Protein Binding, Phosphorylation, Homeostasis, Multigene Family, Molecular Sequence Data, Serine C-Palmitoyltransferase, HeLa Cells, Fatty Acids, Monounsaturated, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7hg193rh

المؤلفون: Xiaoxuan, Liu, Ji, He, Weiyi, Yu, Dongsheng, Fan

المصدر: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 23:634-637

مصطلحات موضوعية: Neurology, Amyotrophic Lateral Sclerosis, Mutation, Serine C-Palmitoyltransferase, Humans, Female, Neurology (clinical), Hereditary Sensory and Autonomic Neuropathies, Child

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6121f8b9e7994691688e0f6446f875b8
https://doi.org/10.1080/21678421.2022.2096409

المؤلفون: Mingione, Alessandra, Dei Cas, Michele, Bonezzi, Fabiola, Caretti, Anna, Piccoli, Marco, Anastasia, Luigi, Ghidoni, Riccardo, Paroni, Rita, Signorelli, Paola

المساهمون: A. Mingione, M. Dei Ca, F. Bonezzi, A. Caretti, M. Piccoli, L. Anastasia, R. Ghidoni, R. Paroni, P. Signorelli

مصطلحات موضوعية: Lipid metabolism, Ceramide, Proteinopathy, Autophagy, Cystic Fibrosi, Basic Helix-Loop-Helix Leucine Zipper Transcription Factor, Cell Line, Cholesterol, Chromatography, High Pressure Liquid, Fatty Acids, Monounsaturated, Forkhead Box Protein O1, Human, Mass Spectrometry, PPAR gamma, RNA Interference, RNA, Small Interfering, Serine C-Palmitoyltransferase, Sphingolipid, Sphingomyelins, Settore BIO/10 - Biochimica, Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica

Relation: info:eu-repo/semantics/altIdentifier/pmid/31999897; volume:54; issue:1; firstpage:110; lastpage:125; numberofpages:16; journal:CELLULAR PHYSIOLOGY AND BIOCHEMISTRY; http://hdl.handle.net/2434/723446; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85079334393

الاتاحة: http://hdl.handle.net/2434/723446
https://doi.org/10.33594/000000208

المؤلفون: Jian Jin, Lei Xu, Li Yu, Jingyu Zhu, Zejun Pei, Yingmin Jiang

المصدر: Chemical Biology & Drug Design. 99:373-381

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Aldimine, Binding Sites, Stereochemistry, Organic Chemistry, Serine C-palmitoyltransferase, Binding energy, Serine C-Palmitoyltransferase, Molecular Dynamics Simulation, Biochemistry, Sphingolipid, Fatty Acids, Monounsaturated, Molecular Docking Simulation, chemistry.chemical_compound, Enzyme, chemistry, Biosynthesis, Docking (molecular), Myriocin, Drug Discovery, Thermodynamics, Molecular Medicine, Enzyme Inhibitors, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2573a91524dda4c11830403b196440
https://doi.org/10.1111/cbdd.13991

المؤلفون: Goon-Tae Kim, Shivani Devi, Amitesh Sharma, Kyung-Hee Cho, Su-Jung Kim, Bo-Rahm Kim, Sang-Ho Kwon, Tae-Sik Park

المصدر: Experimental & Molecular Medicine. 54:573-584

مصطلحات موضوعية: Transcriptional Activation, Clinical Biochemistry, Serine C-Palmitoyltransferase, Ceramides, Endoplasmic Reticulum Stress, Biochemistry, Up-Regulation, Mice, Inbred C57BL, Mice, Liver, Animals, Insulin, Molecular Medicine, Insulin Resistance, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f3a92c62829289660ca4d6a782fca8
https://doi.org/10.1038/s12276-022-00766-4

المؤلفون: Timothy J. Hines, Abigail L. D. Tadenev, Museer A. Lone, Courtney L. Hatton, Inseyah Bagasrawala, Morgane G. Stum, Kathy E. Miers, Thorsten Hornemann, Robert W. Burgess

المصدر: Journal of Anatomy. 241:1169-1185

مصطلحات موضوعية: 0303 health sciences, Histology, Serine C-Palmitoyltransferase, Peripheral Nervous System Diseases, Cell Biology, Ligases, Disease Models, Animal, Mice, 03 medical and health sciences, 0302 clinical medicine, RNA, Transfer, Charcot-Marie-Tooth Disease, Mutation, Animals, Humans, Hereditary Sensory and Autonomic Neuropathies, Anatomy, Molecular Biology, 030217 neurology & neurosurgery, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57fdb80f341fc9a6ec5c5bcb1835baa
https://doi.org/10.1111/joa.13605

المؤلفون: Hongtu Zhao, Alexander G. Myasnikov, Teresa M. Dunn, Sita D. Gupta, Chia-Hsueh Lee, Gongshe Han, Niranjanakumari Somashekarappa, Ravi C. Kalathur, Zhe Zhang, Kenneth Gable, Yingdi Wang, Yiming Niu

المصدر: Nat Struct Mol Biol

مصطلحات موضوعية: Models, Molecular, Membrane lipids, Serine C-Palmitoyltransferase, Ligands, Biochemistry, Article, Substrate Specificity, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Catalytic Domain, Genetics, Humans, SPTLC1, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, Chemistry, Cryoelectron Microscopy, Serine C-palmitoyltransferase, Membrane Proteins, Reproducibility of Results, Substrate (chemistry), Sphingolipid, Cell biology, Enzyme, Membrane, Mutation, Biocatalysis, 030217 neurology & neurosurgery, Biogenesis, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6aa8280079fca6d3e0812eeccb5460
https://doi.org/10.1038/s41594-020-00551-9