المؤلفون: Koichi Ishida, Masaya Matsubayashi, Naoki Ashizawa, Naoki Kurita, Seiichi Kobashi, Shota Morikane, Takashi Iwanaga, Tetsuya Taniguchi

المصدر: Biological and Pharmaceutical Bulletin. 2023, 46(12):1737

المؤلفون: Hajime KUBO, Kimio HIGASHIYAMA, Seiichi KOBASHI, Takayasu YAMAUCHI, 久保 元, 小橋 精一, 山内 貴靖, 東山 公男

المصدر: YAKUGAKU ZASSHI. 2003, 123(5):337

المؤلفون: Hajime Kubo, Kimio Higashiyama, Masayuki Takizawa, Seiichi Kobashi, Takayasu Yamauchi

المصدر: Biological and Pharmaceutical Bulletin. 2003, 26(3):375

المؤلفون: Hajime Kubo, Kimio Higashiyama, Seiichi Kobashi, Takayasu Yamauchi

المصدر: Biological and Pharmaceutical Bulletin. 2002, 25(8):1030

المؤلفون: Kazuki Kawakami, Masaki Ohya, Mitsuru Yashiro, Tomohiro Sonou, Shuto Yamamoto, Yuri Nakashima, Takuro Yano, Yusuke Tanaka, Koichi Ishida, Seiichi Kobashi, Takashi Shigematsu, Shin-ichi Araki

المصدر: Calcified Tissue International.

مصطلحات موضوعية: Endocrinology, Endocrinology, Diabetes and Metabolism, Orthopedics and Sports Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::17dc7c6ba37cdbc668574de0685eda9a
https://doi.org/10.1007/s00223-023-01086-z

المؤلفون: Kengo Miyata, Takashi Iwanaga, Koichi Omura, Keisuke Motoki, Seiichi Kobashi, Katsuhiro Yamano

المصدر: Drug Metabolism and Disposition. 49:1016-1024

مصطلحات موضوعية: Sulfotransferase, Glucuronosyltransferase, Metabolic Clearance Rate, Glucuronidation, Pharmaceutical Science, Hyperuricemia, In Vitro Techniques, Cytosol, Glucuronides, Sulfate conjugate, Sulfation, Humans, Benzothiazoles, Pharmacology, biology, Sulfates, Chemistry, Uric Acid, UGT2B7, Intestines, Isoenzymes, Liver, Biochemistry, Microsomes, Liver, biology.protein, Sulfotransferases, Glucuronide, Algorithms, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2cadb59a775aa39567610b9d0e0b55
https://doi.org/10.1124/dmd.120.000251

المؤلفون: Junichiro Uda, Tomomitsu Sasaki, Seiichi Kobashi, Takashi Iwanaga, Masahiko Fushimi, Tetsuo Ohashi, Azusa Ito, Kengo Miyata, Koichi Omura

المصدر: Drug Metabolism and Pharmacokinetics. 35:313-320

مصطلحات موضوعية: Male, Metabolite, Pharmaceutical Science, Pharmacology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, medicine, Animals, Humans, Pharmacology (medical), Benzothiazoles, Hyperuricemia, 030304 developmental biology, 0303 health sciences, Dose-Response Relationship, Drug, biology, Chemistry, Reabsorption, Cytochrome P450, Haplorhini, Apical membrane, medicine.disease, Rats, Uric Acid, biology.protein, SLC22A12

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0997f6717f192b86434b9b73b894e0ea
https://doi.org/10.1016/j.dmpk.2020.03.002

المؤلفون: Seiichi Kobashi, Junichiro Uda, Takashi Iwanaga, Koji Matsumoto, Naoki Ashizawa

المصدر: Bioorganicmedicinal chemistry letters. 40

مصطلحات موضوعية: Ketone, Uricosuric, Clinical Biochemistry, Drug Evaluation, Preclinical, Glucose Transport Proteins, Facilitative, Pharmaceutical Science, Pharmacology, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Benzbromarone, Structure-Activity Relationship, Uricosuric Agent, Amide, Drug Discovery, medicine, Phenol, Animals, Humans, Pyrroles, Molecular Biology, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Organic Chemistry, Uricosuric Agents, medicine.disease, Amides, 0104 chemical sciences, Mitochondria, Uric Acid, 010404 medicinal & biomolecular chemistry, Mitochondrial toxicity, Sapajus apella, Molecular Medicine, Uric acid, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0cab0eed422b64cc348296700cb2e4
https://pubmed.ncbi.nlm.nih.gov/33684442

المؤلفون: Seiichi Kobashi, Naoki Ashizawa, Ishida Koichi, Takashi Iwanaga, Shota Morikane, Naoki Kurita

المصدر: The Journal of pharmacy and pharmacology. 73(7)

مصطلحات موضوعية: Vitamin, Calcium Phosphates, Calcium-Regulating Hormones and Agents, 030232 urology & nephrology, Pharmaceutical Science, chemistry.chemical_element, 030204 cardiovascular system & hematology, Calcium, Pharmacology, 03 medical and health sciences, Ectopic calcification, chemistry.chemical_compound, 0302 clinical medicine, In vivo, medicine, Animals, Colloids, Vascular Calcification, Diphosphonates, Dose-Response Relationship, Drug, Chemistry, Area under the curve, Etidronic Acid, medicine.disease, In vitro, Rats, Treatment Outcome, Area Under Curve, Ex vivo, Calcification

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c4f5549325c78273828036c66040c8
https://pubmed.ncbi.nlm.nih.gov/33882129

المؤلفون: Junichiro Uda, Takashi Iwanaga, Sachiho Miyata, Naoki Ashizawa, Seiichi Kobashi, Koji Matsumoto

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: chemistry.chemical_classification, Ketone, Uricosuric, 010405 organic chemistry, Organic Chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Benzbromarone, chemistry, Pharmacokinetics, Uricosuric Agent, Drug Discovery, Potency, Uric acid, Phenol

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e374e8be094fc9a5b5103b0a94a62435
https://pubmed.ncbi.nlm.nih.gov/33062187

المؤلفون: Takashi Iwanaga, Ishida Koichi, Koji Matsumoto, Naoki Kurita, Takashi Shigematsu, Naoki Ashizawa, Seiichi Kobashi

المصدر: Journal of bone and mineral metabolism. 37(5)

مصطلحات موضوعية: 0301 basic medicine, Vitamin, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Myocytes, Smooth Muscle, 030209 endocrinology & metabolism, Bone resorption, 03 medical and health sciences, Ectopic calcification, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, In vivo, Internal medicine, medicine, Animals, Humans, Orthopedics and Sports Medicine, Bone Resorption, Rats, Wistar, Vascular Calcification, Aorta, Cells, Cultured, Cholecalciferol, biology, Diphosphonates, Chemistry, Tartrate-Resistant Acid Phosphatase, Acid phosphatase, Etidronic Acid, General Medicine, Bisphosphonate, medicine.disease, biology.protein, 030101 anatomy & morphology, Biomarkers, Calcification, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568217b8d48c60fdd3554a5a383d88f3
https://pubmed.ncbi.nlm.nih.gov/30712064

المؤلفون: Koichi Ishida, Naoki Ashizawa, Shota Morikane, Naoki Kurita, Seiichi Kobashi, Takashi Iwanaga

المصدر: Journal of Pharmacy & Pharmacology; Jul2021, Vol. 73 Issue 7, p947-955, 9p

مصطلحات موضوعية: ARTERIAL calcification, LIGHT absorbance, CHOLECALCIFEROL, BLOOD proteins, AORTA

المؤلفون: Takayasu Yamauchi, Hajime Kubo, Kimio Higashiyama, Seiichi Kobashi

المصدر: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 123(5)

مصطلحات موضوعية: Pharmacology, Male, Analgesics, Mice, Inbred ICR, Contraction (grammar), Tertiary amine, Stereochemistry, Chemistry, Pharmaceutical Science, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Nociception, Structure–activity relationship, Animals, Naphthyridines, Acyl group

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e000a5f13dce25004e988440b7dba8
https://pubmed.ncbi.nlm.nih.gov/12772590