المؤلفون: Santtu Hellström, Antti Sajanti, Aditya Jhaveri, Abhinav Srinath, Carolyn Bennett, Ying Cao, Fredrika Koskimäki, Johannes Falter, Janek Frantzén, Seán B. Lyne, Tomi Rantamäki, Riikka Takala, Jussi P. Posti, Susanna Roine, Sulo Kolehmainen, Miro Jänkälä, Jukka Puolitaival, Romuald Girard, Melissa Rahi, Jaakko Rinne, Eero Castrén, Janne Koskimäki

المصدر: Brain and Spine, Vol 5, Iss , Pp 104173- (2025)

مصطلحات موضوعية: Brain injury, UCHL1, Urine, Outcome, Stroke, Traumatic brain injury, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772529424014292; https://doaj.org/toc/2772-5294

URL الوصول: https://doaj.org/article/be9b530ded9c45969a22393d8dc985c5

المؤلفون: Santtu Hellström, Antti Sajanti, Abhinav Srinath, Carolyn Bennett, Romuald Girard, Aditya Jhaveri, Ying Cao, Johannes Falter, Janek Frantzén, Fredrika Koskimäki, Seán B. Lyne, Tomi Rantamäki, Riikka Takala, Jussi P. Posti, Susanna Roine, Sulo Kolehmainen, Kenneth Nazir, Miro Jänkälä, Jukka Puolitaival, Melissa Rahi, Jaakko Rinne, Anni I. Nieminen, Eero Castrén, Janne Koskimäki

المصدر: Neurobiology of Disease, Vol 204, Iss , Pp 106762- (2025)

مصطلحات موضوعية: Brain injury, Lipidomics, Neurotrophins, Outcome, Prognosis, Stroke, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996124003644; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/90da0f9e950947dcb65a6e055b10492e

المؤلفون: Santtu Hellström, Antti Sajanti, Abhinav Srinath, Carolyn Bennett, Romuald Girard, Ying Cao, Janek Frantzén, Fredrika Koskimäki, Johannes Falter, Seán B. Lyne, Tomi Rantamäki, Riikka Takala, Jussi P. Posti, Susanna Roine, Jukka Puolitaival, Miro Jänkälä, Sulo Kolehmainen, Melissa Rahi, Jaakko Rinne, Eero Castrén, Janne Koskimäki

المصدر: Biomedicines, Vol 12, Iss 1, p 112 (2024)

مصطلحات موضوعية: neurotrophins, brain injury, stroke, trauma, outcome, recovery, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/1/112; https://doaj.org/toc/2227-9059

URL الوصول: https://doaj.org/article/a83bd9a89d19490d8305c43d8fda22de

المؤلفون: Iiro Heino, Antti Sajanti, Seán B. Lyne, Janek Frantzén, Romuald Girard, Ying Cao, Joel F. Ritala, Ari J. Katila, Riikka S.K. Takala, Jussi P. Posti, Antti J. Saarinen, Santtu Hellström, Dan Laukka, Ilkka Saarenpää, Melissa Rahi, Olli Tenovuo, Jaakko Rinne, Janne Koskimäki

المصدر: Brain and Spine, Vol 3, Iss , Pp 102714- (2023)

مصطلحات موضوعية: Acute subdural hematoma, Postcraniotomy hematoma, Outcome, Survival, Surgery, Traumatic brain injury, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772529423010020; https://doaj.org/toc/2772-5294

URL الوصول: https://doaj.org/article/93f3bb6176ff4d24b937d2023cc3af15

المؤلفون: Sean P. Polster, Anukriti Sharma, Ceylan Tanes, Alan T. Tang, Patricia Mericko, Ying Cao, Julián Carrión-Penagos, Romuald Girard, Janne Koskimäki, Dongdong Zhang, Agnieszka Stadnik, Sharbel G. Romanos, Seán B. Lyne, Robert Shenkar, Kimberly Yan, Cornelia Lee, Amy Akers, Leslie Morrison, Myranda Robinson, Atif Zafar, Kyle Bittinger, Helen Kim, Jack A. Gilbert, Mark L. Kahn, Le Shen, Issam A. Awad

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/79327732fdd1439bb531e46396ad13b9

المؤلفون: Janne Koskimäki, Dongdong Zhang, Yan Li, Laleh Saadat, Thomas Moore, Rhonda Lightle, Sean P. Polster, Julián Carrión-Penagos, Seán B. Lyne, Hussein A. Zeineddine, Changbin Shi, Robert Shenkar, Sharbel Romanos, Kenneth Avner, Abhinav Srinath, Le Shen, Matthew R. Detter, Daniel Snellings, Ying Cao, Miguel A. Lopez-Ramirez, Gregory Fonseca, Alan T. Tang, Pieter Faber, Jorge Andrade, Mark Ginsberg, Mark L. Kahn, Douglas A. Marchuk, Romuald Girard, Issam A. Awad

المصدر: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)

مصطلحات موضوعية: Cerebral cavernous malformation, Cavernous angioma, Hemangioma, Ccm3, Mouse model, Transcriptome, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-019-0789-0; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/d491481086084d3caa544cf265ff3ba4

المؤلفون: Joel F Ritala, Seán B Lyne, Antti Sajanti, Romuald Girard, Janne Koskimäki

المصدر: Neural Regeneration Research, Vol 17, Iss 4, Pp 701-704 (2022)

مصطلحات موضوعية: bioinformatics, brain injury, data mining, neuron, neurotrophins, p75ntr, plasticity, regeneration, Neurology. Diseases of the nervous system, RC346-429

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=4;spage=701;epage=704;aulast=; https://doaj.org/toc/1673-5374; https://doaj.org/article/6cbf3a2102f24cf39f6f8b4320522b5d

الاتاحة: https://doi.org/10.4103/1673-5374.314291
https://doaj.org/article/6cbf3a2102f24cf39f6f8b4320522b5d

المؤلفون: Seán B. Lyne, Bakhtiar Yamini

المصدر: Cancers; Volume 13; Issue 8; Pages: 1953

مصطلحات موضوعية: glioblastoma, GBM, therapeutics, chemosensitization, radiosensitization, repurposing, repositioning

وصف الملف: application/pdf

Relation: Molecular Cancer Biology; https://dx.doi.org/10.3390/cancers13081953

الاتاحة: https://doi.org/10.3390/cancers13081953

المؤلفون: Ali Mansour, Daniel F. Hanley, Barbara A. Gregson, Robert L. Dodd, Andrew P. Carlson, Wendy C. Ziai, Mark R. Harrigan, Paul J. Camarata, Issam A. Awad, Jean-Louis Caron, Sean P. Polster, Mario Zuccarello, Julián Carrión-Penagos, Seán B. Lyne, Fernando D. Goldenberg, A. David Mendelow

المصدر: Oper Neurosurg (Hagerstown)

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, 030204 cardiovascular system & hematology, law.invention, 03 medical and health sciences, 0302 clinical medicine, Fibrinolytic Agents, Randomized controlled trial, law, medicine, Minimally Invasive Surgical Procedures, Humans, Thrombolytic Therapy, Dosing, Intensive care medicine, Cerebral Hemorrhage, Protocol (science), Intracerebral hemorrhage, business.industry, Thrombolysis, medicine.disease, Cerebral Intraventricular Hemorrhage, Intraventricular hemorrhage, Tissue Plasminogen Activator, Emergency evacuation, Surgery, Neurology (clinical), business, Concepts, Innovations and Techniques, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7037962ad214ce57388638858647114a
https://doi.org/10.1093/ons/opaa306

المؤلفون: Sean P. Polster, Ali Mansour, Seán B. Lyne

المصدر: World Neurosurgery. 139:215-218

مصطلحات موضوعية: Disseminated intravascular coagulation, medicine.medical_specialty, business.industry, Glasgow Coma Scale, Guideline, medicine.disease, Surgery, 03 medical and health sciences, Venous thrombosis, 0302 clinical medicine, Modified Rankin Scale, 030220 oncology & carcinogenesis, medicine, Intracranial pressure monitoring, Neurology (clinical), business, Stroke, 030217 neurology & neurosurgery, External ventricular drain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5cdab0478cf1e307e89fecdc03054564
https://doi.org/10.1016/j.wneu.2020.03.220

المؤلفون: Issam A. Awad, Sean P. Polster, Dongdong Zhang, Seán B. Lyne, Romuald Girard, Janne Koskimäki, Julián Carrión-Penagos, Agnieszka Stadnik, Kristina Piedad

المصدر: World Neurosurgery. 136:7-11

مصطلحات موضوعية: Adult, Pathology, medicine.medical_specialty, Brain hemorrhage, Lipopolysaccharide, Migraine Disorders, Neurotoxins, MAP Kinase Kinase Kinase 3, Angioma, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Chronic Migraine, medicine, High doses, Humans, Botulinum Toxins, Type A, Stroke, Brain Neoplasms, business.industry, Mechanism (biology), Toll-Like Receptors, medicine.disease, Botulinum toxin, Hemangioma, Cavernous, chemistry, 030220 oncology & carcinogenesis, Female, Surgery, Neurology (clinical), Chronic Pain, business, Intracranial Hemorrhages, Magnetic Resonance Angiography, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f2eff9539076efdd649e07770bcc32
https://doi.org/10.1016/j.wneu.2019.12.172

المؤلفون: Shiraz Fidai, Peter Pytel, Bakhtiar Yamini, Sean P. Polster, Seán B. Lyne

المصدر: World Neurosurgery. 125:32-36

مصطلحات موضوعية: Adenoma, medicine.medical_specialty, Optic chiasm, Diagnosis, Differential, Paraganglioma, Meningioma, 03 medical and health sciences, 0302 clinical medicine, Pituitary adenoma, medicine, Humans, Pituitary Neoplasms, Sella Turcica, Aged, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, medicine.disease, Craniopharyngioma, medicine.anatomical_structure, Optic Chiasm, 030220 oncology & carcinogenesis, Female, Surgery, Neurology (clinical), Radiology, Differential diagnosis, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19372592c203fd032e5ab4334e08a7c0
https://doi.org/10.1016/j.wneu.2019.01.094

المؤلفون: Issam A. Awad, Sean P. Polster, Douglas A. Marchuk, Amy Peiper, Dongdong Zhang, Thomas R. Moore, Robert Shenkar, Seán B. Lyne, Heidy Pardo, James K. Liao, Kiranj K. Chaudagar, Carol J. Gallione, Nicholas Hobson, Rhonda Lightle, Ying Cao, Peter Pytel, Romuald Girard, Laleh Saadat, Janne Koskimäki

المصدر: Stroke. 50:738-744

مصطلحات موضوعية: Hemangioma, Cavernous, Central Nervous System, Simvastatin, Atorvastatin, Central nervous system, Disease, Pharmacology, Article, Hemangioma, Lesion, Mice, 03 medical and health sciences, 0302 clinical medicine, 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine, medicine, Animals, Enzyme Inhibitors, KRIT1 Protein, Rho-associated protein kinase, 030304 developmental biology, Mice, Knockout, Advanced and Specialized Nursing, rho-Associated Kinases, 0303 health sciences, business.industry, Intracellular Signaling Peptides and Proteins, nutritional and metabolic diseases, X-Ray Microtomography, medicine.disease, medicine.anatomical_structure, Neurology (clinical), Hydroxymethylglutaryl-CoA Reductase Inhibitors, medicine.symptom, Apoptosis Regulatory Proteins, Cardiology and Cardiovascular Medicine, business, Intracranial Hemorrhages, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918a590d922d0e68554d35a5c165193e
https://doi.org/10.1161/strokeaha.118.024058

المؤلفون: Agnieszka Stadnik, Rhonda Lightle, Issam A. Awad, Timothy J. Carroll, Kristina Piedad, Yuan Ji, Abhinav Srinath, Je Yeong Sone, Julián Carrión-Penagos, Romuald Girard, Robert Shenkar, Thomas R. Moore, Nicholas Hobson, Dehua Bi, Yan Li, Ying Li, Abdallah Shkoukani, Sharbel Romanos, Seán B. Lyne

المصدر: J Cereb Blood Flow Metab

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Genotype, Perfusion Imaging, Contrast Media, Hemorrhage, Vascular leakage, Sensitivity and Specificity, Permeability, Angioma, Cohort Studies, Machine Learning, 03 medical and health sciences, 0302 clinical medicine, medicine, Diagnostic biomarker, Humans, 030304 developmental biology, 0303 health sciences, business.industry, Mr perfusion, Bayes Theorem, Blood flow, Original Articles, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Perfusion, Hemangioma, Cavernous, Logistic Models, Neurology, Permeability (electromagnetism), Case-Control Studies, Cerebrovascular Circulation, Cavernous angiomas, Female, Neurology (clinical), Radiology, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery, Biomarkers, Brain Stem

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b406f2900072a2e30a7813d89c9b8b
https://pubmed.ncbi.nlm.nih.gov/34039038

المؤلفون: Tomi Rantamäki, Eero Castrén, Fredrika Koskimäki, Melissa Rahi, Cassiano R.A.F. Diniz, Janne Koskimäki, Yan Li, Janek Frantzén, Jaakko Rinne, Jussi P. Posti, Iiro Heino, Antti Sajanti, Seán B. Lyne, Riikka S.K. Takala, Romuald Girard, Susanna Roine, Ying Cao

المصدر: Stroke. 52

مصطلحات موضوعية: Advanced and Specialized Nursing, biology, business.industry, medicine.medical_treatment, Regeneration (biology), Gene regulatory network, 030204 cardiovascular system & hematology, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, medicine, biology.protein, Low-affinity nerve growth factor receptor, sense organs, Neurology (clinical), Cardiology and Cardiovascular Medicine, Stroke recovery, business, Stroke, Neuroscience, Gene, 030217 neurology & neurosurgery, Neurotrophin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eb8706653d8baf62981379c006005e07
https://doi.org/10.1161/str.52.suppl_1.p809

المؤلفون: Je Yeong Sone (10891241), Yan Li (23143), Nicholas Hobson (10891244), Sharbel G Romanos (10891247), Abhinav Srinath (7284503), Seán B Lyne (10891250), Abdallah Shkoukani (10891253), Julián Carrión-Penagos (7284485), Agnieszka Stadnik (5746826), Kristina Piedad (10891256), Rhonda Lightle (7284479), Thomas Moore (1312581), Ying Li (38224), Dehua Bi (3621809), Robert Shenkar (7284494), Timothy Carroll (3762841), Yuan Ji (5702), Romuald Girard (7284518), Issam A Awad (6559178)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Neuroscience, Emergency Medicine, Endocrinology, Radiology and Organ Imaging, Neurology and Neuromuscular Diseases, Biological Sciences not elsewhere classified, Cavernous angioma with symptomatic hemorrhage, biomarkers, MR permeability, MR perfusion, machine learning

Relation: https://figshare.com/articles/journal_contribution/sj-pdf-1-jcb-10_1177_0271678X211020587_-_Supplemental_material_for_Perfusion_and_permeability_as_diagnostic_biomarkers_of_cavernous_angioma_with_symptomatic_hemorrhage/14695949

الاتاحة: https://doi.org/10.25384/sage.14695949.v1

المؤلفون: Juzoh Umemori, Cassiano R.A.F. Diniz, Yan Li, Fredrika Koskimäki, Janek Frantzén, Susanna Roine, Eero Castrén, Ying Cao, Romuald Girard, Riikka S.K. Takala, Janne Koskimäki, Melissa Rahi, Antti Sajanti, Jaakko Rinne, Jussi P. Posti, Tomi Rantamäki, Iiro Heino, Seán B. Lyne

المساهمون: Drug Research Program, Division of Pharmacology and Pharmacotherapy, Laboratory of Neurotherapeutics, Molecular and Integrative Biosciences Research Programme, Neuroscience Center

المصدر: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)

مصطلحات موضوعية: EXPRESSION, False discovery rate, PubMed, TISSUES, Cellular adaptation, Gene regulatory network, lcsh:Medicine, Nerve Tissue Proteins, Receptors, Nerve Growth Factor, Computational biology, Biology, Molecular neuroscience, Article, ACTIVATION, 03 medical and health sciences, 0302 clinical medicine, Growth factor receptor, Interaction network, KINASE, Data Mining, Humans, Gene Regulatory Networks, BRAIN, MOLECULE, lcsh:Science, Gene, 030304 developmental biology, 0303 health sciences, Multidisciplinary, TRK RECEPTORS, lcsh:R, 3112 Neurosciences, Neurodegenerative Diseases, RECOVERY, P75(NTR), Brain Injuries, Trk receptor, Diseases of the nervous system, lcsh:Q, sense organs, Signal transduction, GROWTH-FACTOR RECEPTOR, Algorithms, Metabolic Networks and Pathways, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d89f49badf8b0e5c00f91763daa963c
http://europepmc.org/articles/PMC7486379

المؤلفون: Issam A. Awad, A. David Mendelow, Ahmed Iqbal, Yi Hao, Barbara A. Gregson, Richard E. Thompson, Jean-Louis Caron, Nichol McBee, Romuald Girard, Mark R. Harrigan, Sean P. Polster, Patricia Lynn Money, Ying Cao, Andrew P. Carlson, Robert L. Dodd, Mario Zuccarello, Agnieszka Stadnik, Daniel F. Hanley, Paul J. Camarata, Karen Lane, Julián Carrión-Penagos, Seán B. Lyne, Stephen Metcalfe, W. Andrew Mould, Wendy C. Ziai

المصدر: Neurosurgery. 88(5)

مصطلحات موضوعية: medicine.medical_specialty, medicine.medical_treatment, Time-to-Treatment, 03 medical and health sciences, 0302 clinical medicine, Time windows, Modified Rankin Scale, Medicine, Volume reduction, Humans, Minimally Invasive Surgical Procedures, Thrombolytic Therapy, 030212 general & internal medicine, Craniotomy, Cerebral Hemorrhage, Intracerebral hemorrhage, business.industry, Thrombolysis, Risk adjustment, medicine.disease, Surgery, Treatment Outcome, Cohort, Neurology (clinical), business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0cb8ca8504710d77fbe1dc24b2bc9f3
https://pubmed.ncbi.nlm.nih.gov/34333661

المؤلفون: Agnieszka Stadnik, Kristina Piedad, Seán B. Lyne, Dongdong Zhang, Rhonda Lightle, Gregory A. Christoforidis, Timothy J. Carroll, Yan Li, Thomas R. Moore, Alexey Dimov, Sharbel Romanos, Issam A. Awad, Abhinav Srinath, Janne Koskimäki, Robert Shenkar, Sean P. Polster, Nicholas Hobson, Julián Carrión-Penagos, Romuald Girard, Ying Cao

المصدر: GeroScience

مصطلحات موضوعية: Senescence, Vascular Endothelial Growth Factor A, Pathology, medicine.medical_specialty, Aging, Hemangioma, Cavernous, Central Nervous System, Vascular permeability, Inflammation, chemistry.chemical_compound, Plasma, medicine, Aging brain, Humans, Pathological, Aged, business.industry, Brain, Fold change, Vascular endothelial growth factor, chemistry, Original Article, Geriatrics and Gerontology, medicine.symptom, business, Transcriptome, Extracellular matrix organization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d557dd57134ce055183b942650de4061
https://pubmed.ncbi.nlm.nih.gov/32556941

المؤلفون: Janne Koskimäki, Seán B. Lyne, Leslie Morrison, Amy Akers, James I. Koenig, Romuald Girard, Cornelia Lee, Matthew J. Sorrentino, Gregory A. Christoforidis, Issam A. Awad, Maged D Fam, Robert Shenkar, Sean P. Polster, Agnieszka Stadnik, James K. Liao, Ying Cao, Kelly D. Flemming, Daniel F. Hanley, Karen Lane, Kristina Piedad, Nicholas Hobson, Richard E. Thompson, Nichol McBee, Kevin J. Whitehead, Hussein A. Zeineddine

المصدر: Neurosurgery

مصطلحات موضوعية: Male, Hemangioma, Cavernous, Central Nervous System, medicine.medical_specialty, Atorvastatin, Placebo, Proof of Concept Study, Angioma, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Internal medicine, Humans, Medicine, Prospective Studies, Dosing, Adverse effect, Protein Kinase Inhibitors, Cerebral Hemorrhage, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, medicine.disease, Magnetic Resonance Imaging, Clinical trial, Hemangioma, Cavernous, Treatment Outcome, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, Surgery, Neurology (clinical), rhoA GTP-Binding Protein, business, Research—Human—Study Protocols, 030217 neurology & neurosurgery, Follow-Up Studies, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fcb3ecf7eef48b0050a3414154e855
https://doi.org/10.1093/neuros/nyy539