المؤلفون: Andrew J. Kennedy, Joseph D. Houck, Thomas K. Dawson, Saundra D. Field, Niels D. Naimon, Kevin R. Lynch, Yugesh Kharel, Timothy L. Macdonald

مصطلحات موضوعية: 0301 basic medicine, biology, Sphingosine, Organic Chemistry, Sphingosine kinase, Oxadiazole, Biochemistry, Amidine, 03 medical and health sciences, chemistry.chemical_compound, SPHK2, 030104 developmental biology, Sphingosine kinase 1, chemistry, Docking (molecular), Drug Discovery, biology.protein, Sphingosine-1-phosphate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bfa952692ac007c2c1577103f44437
https://europepmc.org/articles/PMC4867490/

المؤلفون: Joseph D. Houck, Timothy L. Macdonald, Yugesh Kharel, James E. East, Saundra D. Field, Andrew J. Kennedy, Morgan L. Moyer, Kevin R. Lynch, Thomas P. Mathews

المصدر: Journal of Medicinal Chemistry. 54:3524-3548

مصطلحات موضوعية: Models, Molecular, Chemistry, Pharmaceutical, Amidines, Antineoplastic Agents, Article, Amidine, chemistry.chemical_compound, Sphingosine, Cell Line, Tumor, Drug Discovery, medicine, Humans, Sphingosine-1-phosphate, Enzyme Inhibitors, Leukemia, biology, U937 cell, Gene Expression Regulation, Leukemic, Kinase, Cancer, U937 Cells, medicine.disease, Kinetics, Phosphotransferases (Alcohol Group Acceptor), SPHK2, Models, Chemical, chemistry, Biochemistry, Sphingosine kinase 1, Drug Design, biology.protein, Molecular Medicine, Lysophospholipids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd6baf3fc66c36c987c285d398789fd
https://doi.org/10.1021/jm2001053