المؤلفون: akio watanabe, hideaki hujii, hiroshi nagase, satomi imaide, 今出 慧海, 渡辺 晃生, 藤井 秀明, 長瀬 博

المصدر: Proceedings of the Symposium on Progress in Organic Reactions and Syntheses. 2007, :115

المؤلفون: akio watanabe, hideaki fujii, hiroshi nagase, satomi imaide, 今出 慧海, 渡辺 晃生, 藤井 秀明, 長瀬 博

المصدر: Proceedings of the Symposium on Progress in Organic Reactions and Syntheses. 2009, :121

المؤلفون: Hiroaki Goda, Hiroshi Nagase, Miyuki Tomatsu, Noriko Sato, Satomi Imaide, Syuichi Hirono, 今出 慧海, 佐藤 倫子, 合田 浩明, 広野 修一, 戸松 美有季, 長瀬 博

المصدر: Proceedings of the Symposium on Progress in Organic Reactions and Syntheses. 2009, :120

المؤلفون: Hiroshi Nagase, Koji Koyano, Naohisa Wada, Satomi Imaide, Shigeto Hirayama, 今出 慧海, 古谷野 浩治, 和田 直久, 平山 重人, 長瀬 博

المصدر: Proceedings of the Symposium on Progress in Organic Reactions and Syntheses. 2010, :46

المؤلفون: Akio Watanabe, Hideaki Fujji, Hiroaki Gouda, Hiroshi Nagase, Miyuki Tomatsu, Noriko Sato, Satomi Imaide, Shuichi Hirono, 今出 慧海, 佐藤 倫子, 合田 浩明, 広野 修一, 戸松 美有季, 渡邊 晃生, 藤井 秀明, 長瀬 博

المصدر: Proceedings of the Symposium on Progress in Organic Reactions and Syntheses. 2010, :101

المؤلفون: hiroshi nagase, hiroshi tomoda, junji inokoshi, naoshi yamamoto, satomi imaide, 今出 慧海, 供田 洋, 山本 直司, 猪腰 淳嗣, 長瀬 博

المصدر: Proceedings of the Symposium on Progress in Organic Reactions and Syntheses. 2011, :82

المؤلفون: Vesna Vetma, Kristin M. Riching, Satomi Imaide, Marjeta Urh, Claire Whitworth, Chiara Maniaci, Angus D. Cowan, Nicole Trainor, Sarah D. Mahan, Alessio Ciulli, Andrea Testa, Nancy Murphy, Conner Craigon, Kwok-Ho Chan, Nikolai Makukhin, Scott J. Hughes, Danette L. Daniels

المصدر: Nature chemical biology

مصطلحات موضوعية: 0303 health sciences, 010405 organic chemistry, Chemistry, Ubiquitin-Protein Ligases, Cooperative binding, Cooperativity, Cell Biology, Protein degradation, Ligand (biochemistry), 01 natural sciences, Article, 0104 chemical sciences, Bromodomain, 03 medical and health sciences, Proteolysis, Biophysics, Humans, Target protein, Molecular Biology, Linker, Ternary complex, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48142d6a1b031c2e4ceee52a00283704
https://doi.org/10.1038/s41589-021-00878-4

المؤلفون: Alessandra Cipriano, Ciro Milite, Alessandra Feoli, Monica Viviano, Giacomo Pepe, Pietro Campiglia, Giuliana Sarno, Sarah Picaud, Satomi Imaide, Nikolai Makukhin, Panagis Filippakopoulos, Alessio Ciulli, Sabrina Castellano, Gianluca Sbardella

المصدر: ChemMedChem. 17

مصطلحات موضوعية: Pharmacology, Organic Chemistry, Drug Discovery, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9b5edef4d66f5f45de556d8c894a9297
https://doi.org/10.1002/cmdc.202200528

المؤلفون: Alessandra Cipriano, Ciro Milite, Alessandra Feoli, Monica Viviano, Giacomo Pepe, Pietro Campiglia, Giuliana Sarno, Sarah Picaud, Satomi Imaide, Nikolai Makukhin, Panagis Filippakopoulos, Alessio Ciulli, Sabrina Castellano, Gianluca Sbardella

مصطلحات موضوعية: Male, Pharmacology, Sulfonamides, Bioisosteres, Organic Chemistry, Imidazoles, Nuclear Proteins, Bromodomain, Cell Cycle Proteins, Structure-activity relationships, Biochemistry, Benzimidazole-6-sulfonamide, Selectivity, Drug Discovery, Benzo(a)pyrene, Humans, Molecular Medicine, Benzimidazoles, General Pharmacology, Toxicology and Pharmaceutics, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97485ad4f5fc3bfd314a88b32c4c543
http://hdl.handle.net/11386/4803392

المؤلفون: Sarah D. Mahan, Kristin M. Riching, Claire Whitworth, Marjeta Urh, Chiara Maniaci, Alessio Ciulli, Satomi Imaide, Nicole Trainor, Andrea Testa, Vesna Vetma, Nancy Murphy, Kwok-Ho Chan, Danette L. Daniels, Scott J. Hughes

مصطلحات موضوعية: biology, Chemistry, biology.protein, Biophysics, Cooperativity, Avidity, Target protein, Protein degradation, Ligand (biochemistry), Ternary complex, Ubiquitin ligase, Bromodomain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f76c01ffacb55b1f5c21e4c3fe9567
https://doi.org/10.26434/chemrxiv.13218695

المؤلفون: Takahiro Okada, Satomi Imaide, Noriki Kutsumura, Hiroshi Nagase, Hideaki Fujii

المصدر: Synthesis. 50:4263-4269

مصطلحات موضوعية: Reaction mechanism, Nucleophilic addition, 010405 organic chemistry, Organic Chemistry, 010402 general chemistry, 01 natural sciences, Medicinal chemistry, Catalysis, 0104 chemical sciences, chemistry.chemical_compound, Propellane, Acetic anhydride, Acetoxy group, chemistry, Ammonium, Derivative (chemistry), Ene reaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fae6ba250a8d98b37c840896d892c182
https://doi.org/10.1055/s-0036-1589138

المؤلفون: Hideaki Fujii, Noriki Kutsumura, Satomi Imaide, Takahiro Okada, Tsuyoshi Saitoh, Hiroshi Nagase, Yukimasa Harada, Naoshi Yamamoto

المصدر: Tetrahedron. 73:5751-5758

مصطلحات موضوعية: Morphinan, 010405 organic chemistry, Organic Chemistry, Imine, chemistry.chemical_element, Zinc, 010402 general chemistry, 01 natural sciences, Biochemistry, Reductive amination, Medicinal chemistry, 0104 chemical sciences, chemistry.chemical_compound, Acetic acid, Combination reaction, chemistry, Yield (chemistry), Drug Discovery, Hofmann elimination, Organic chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fed2ae72d6de00434e5406eaa28b0a32
https://doi.org/10.1016/j.tet.2017.08.014

المؤلفون: Shigeto Hirayama, Hideaki Fujii, Satomi Imaide, Hiroshi Nagase, Kazuya Konoura, Shuichi Hirono, Hiroaki Gouda

المصدر: Bioorganic & Medicinal Chemistry. 23:439-448

مصطلحات موضوعية: Morphinan, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, CHO Cells, Morphinans, Ligands, Ring (chemistry), Biochemistry, Naltrexone, Indole Alkaloids, Structure-Activity Relationship, chemistry.chemical_compound, Cricetulus, Opioid receptor, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Membranes, Organic Chemistry, Affinities, chemistry, Opioid, Drug Design, Receptors, Opioid, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0280c809e109fc54961e64784ff22177
https://doi.org/10.1016/j.bmc.2014.12.032

المؤلفون: Shigeto Hirayama, Hideaki Fujii, Hiroshi Nagase, Satomi Imaide, Shuichi Hirono, Hiroaki Gouda, Toru Nemoto

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:7711-7714

مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Morphinans, Biochemistry, Structure-Activity Relationship, Opioid receptor, Drug Discovery, medicine, Structure–activity relationship, Receptor, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, Hydrogen bond, Chemistry, Receptors, Opioid, kappa, Organic Chemistry, Phenanthrenes, Affinities, Oxygen, Drug Design, Molecular Medicine, Nalfurafine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef697b2e0387a8143aa0586c0314d7f1
https://doi.org/10.1016/j.bmcl.2012.09.101

المؤلفون: Shigeto Hirayama, Hideaki Fujii, Satomi Imaide, Toru Nemoto, Hiroshi Nagase

المصدر: Bioorganic & Medicinal Chemistry Letters. 22:5071-5074

مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Cyclohexene, Pharmaceutical Science, Ring (chemistry), Biochemistry, chemistry.chemical_compound, Amide, Cyclohexenes, Drug Discovery, medicine, Side chain, Moiety, Spiro Compounds, Molecular Biology, Receptors, Opioid, kappa, Organic Chemistry, Phenanthrenes, Morphinans, chemistry, Opioid, Molecular Medicine, Nalfurafine, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782e2714e2231970d707127f6f688a33
https://doi.org/10.1016/j.bmcl.2012.05.122

المؤلفون: Satomi Imaide, Toru Nemoto, Takaaki Yamada, Noriyuki Yamaotsu, Shuichi Hirono, Shigeto Hirayama, Hiroshi Nagase, Hideaki Fujii

المصدر: Chemical and Pharmaceutical Bulletin. 60:945-948

مصطلحات موضوعية: Models, Molecular, Agonist, Molecular Structure, medicine.drug_class, Stereochemistry, Receptors, Opioid, kappa, General Chemistry, General Medicine, Isoquinolines, chemistry.chemical_compound, Morphinans, Opioid, chemistry, Opioid receptor, Amide, Drug Discovery, medicine, Side chain, Spiro Compounds, Pharmacophore, Receptor, Nalfurafine, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669b480caf85e29cefb2e79d32330cac
https://doi.org/10.1248/cpb.c12-00336

المؤلفون: Satomi Imaide, Hideaki Fujii, Kaoru Nakao, Hidenori Mochizuki, Akio Watanabe, Hiroshi Nagase, Mayumi Nakajima, Toru Nemoto

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1055-1058

مصطلحات موضوعية: Models, Molecular, Ethylene, Stereochemistry, Chemistry, Hydrogen bond, medicine.drug_class, Chemistry, Pharmaceutical, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Affinities, Chemical synthesis, Naltrexone, Structure-Activity Relationship, chemistry.chemical_compound, Opioid receptor, Intramolecular force, Drug Discovery, medicine, Molecular Medicine, Moiety, Molecular Biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4e23347f4bcc6236ba9e26d9e3d28b
https://doi.org/10.1016/j.bmcl.2009.12.039

المؤلفون: Hiroshi Nagase, Toru Nemoto, Akio Watanabe, Satomi Imaide, Hideaki Fujii

المصدر: Tetrahedron Letters. 49:6293-6296

مصطلحات موضوعية: Reaction mechanism, Morphinan, Stereochemistry, Organic Chemistry, Stereoelectronic effect, Chloroformate, Alkylation, Biochemistry, Naltrexone, chemistry.chemical_compound, chemistry, Derivative (finance), Drug Discovery, medicine, Morphinan derivatives, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::57f660f4349da3567baba1159dce19ec
https://doi.org/10.1016/j.tetlet.2008.08.037

المؤلفون: Hiroshi Nagase, Toru Nemoto, Noriyuki Yamaotsu, Takaaki Yamada, Hideaki Fujii, Shuichi Hirono, Shigeto Hirayama, Satomi Imaide

المصدر: ChemInform. 44

مصطلحات موضوعية: Agonist, Opioid, medicine.drug_class, Opioid receptor, Chemistry, Stereochemistry, medicine, Structure–activity relationship, General Medicine, Receptor, humanities, Nalfurafine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::04d33c8ddace47221206ae7a358ab574
https://doi.org/10.1002/chin.201303181

المؤلفون: Toru Nemoto, Junji Inokoshi, Hiroshi Nagase, Hiroshi Tomoda, Naoshi Yamamoto, Satomi Imaide, Shigeto Hirayama, Hideaki Fujii

المصدر: The Journal of organic chemistry. 76(7)

مصطلحات موضوعية: Grob fragmentation, Magnetic Resonance Spectroscopy, Molecular Structure, Stereochemistry, medicine.drug_class, Chemistry, Galantamine, Narcotic Antagonists, Organic Chemistry, Antagonist, Receptors, Opioid, mu, Chemical synthesis, Naltrexone, Acetylcholinesterase inhibitor, Yield (chemistry), Crown Ethers, medicine, Opioid antagonist, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a9f7dac696c373b7939f2e700b57529
https://pubmed.ncbi.nlm.nih.gov/21381712