المؤلفون: Xia, Dan, Lianoglou, Steve, Sandmann, Thomas, Calvert, Meredith, Suh, Jung H, Thomsen, Elliot, Dugas, Jason, Pizzo, Michelle E, DeVos, Sarah L, Earr, Timothy K, Lin, Chia-Ching, Davis, Sonnet, Ha, Connie, Leung, Amy Wing-Sze, Nguyen, Hoang, Chau, Roni, Yulyaningsih, Ernie, Lopez, Isabel, Solanoy, Hilda, Masoud, Shababa T, Liang, Chun-chi, Lin, Karin, Astarita, Giuseppe, Khoury, Nathalie, Zuchero, Joy Yu, Thorne, Robert G, Shen, Kevin, Miller, Stephanie, Palop, Jorge J, Garceau, Dylan, Sasner, Michael, Whitesell, Jennifer D, Harris, Julie A, Hummel, Selina, Gnörich, Johannes, Wind, Karin, Kunze, Lea, Zatcepin, Artem, Brendel, Matthias, Willem, Michael, Haass, Christian, Barnett, Daniel, Zimmer, Till S, Orr, Anna G, Scearce-Levie, Kimberly, Lewcock, Joseph W, Di Paolo, Gilbert, Sanchez, Pascal E

المصدر: Molecular Neurodegeneration. 17(1)

مصطلحات موضوعية: Neurosciences, Aging, Acquired Cognitive Impairment, Alzheimer's Disease, Biotechnology, Genetics, Neurodegenerative, Brain Disorders, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Dementia, Aetiology, 2.1 Biological and endogenous factors, Neurological, Alzheimer Disease, Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Amyloidosis, Animals, Brain, Disease Models, Animal, Mice, Mice, Transgenic, Microglia, Plaque, Amyloid, Receptors, GABA, Neuritic plaques, Vascular amyloid, Neurodegeneration, Astrogliosis, Phagocytic microglia, Lipid dyshomeostasis, Clinical Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/447239vz
https://escholarship.org/content/qt447239vz/qt447239vz.pdf

المؤلفون: Oblak, Adrian L, Cope, Zackary A, Quinney, Sara K, Pandey, Ravi S, Biesdorf, Carla, Masters, Andi R, Onos, Kristen D, Haynes, Leslie, Keezer, Kelly J, Meyer, Jill A, Peters, Jonathan S, Persohn, Scott A, Bedwell, Amanda A, Eldridge, Kierra, Speedy, Rachael, Little, Gabriela, Williams, Sean‐Paul, Noarbe, Brenda, Obenaus, Andre, Sasner, Michael, Howell, Gareth R, Carter, Gregory W, Williams, Harriet, Lamb, Bruce T, Territo, Paul R, Rizzo, Stacey J Sukoff

المصدر: Alzheimer's & Dementia: Translational Research & Clinical Interventions. 8(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Biological Psychology, Clinical Sciences, Psychology, Pharmacology and Pharmaceutical Sciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease, Biomedical Imaging, Neurosciences, Brain Disorders, Dementia, Neurodegenerative, Aging, Acquired Cognitive Impairment, Prevention, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Neurological, amyloid, BACE inhibitor, MODEL-AD, mouse model, preclinical testing, MODEL‐AD, Clinical sciences, Biological psychology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/08m5g6f5

المؤلفون: Sasner, Michael, Preuss, Christoph, Pandey, Ravi S, Uyar, Asli, Garceau, Dylan, Kotredes, Kevin P, Jackson, Harriet M, Oblak, Adrian L, Lin, Peter Bor-Chian, Perkins, Bridget, Soni, Disha, Ingraham, Cindy, Lee-Gosselin, Audrey, Lamb, Bruce T, Howell, Gareth R, Carter, Gregory W

المصدر: Faculty Research 2024

مصطلحات موضوعية: JGM, JMG, SS1, Alzheimer Disease, Animals, Mice, Humans, Risk Factors, Transgenic, Disease Models, Animal, Genetic Predisposition to Disease, Genome-Wide Association Study, Male, Brain, Female

وصف الملف: application/pdf

Relation: https://mouseion.jax.org/stfb2024/210; https://mouseion.jax.org/context/stfb2024/article/1179/viewcontent/Alzheimer_s_Dementia___2024___Sasner___In_vivo_validation_of_late_onset_Alzheimer_s_disease_genetic_risk_factors.pdf

الاتاحة: https://mouseion.jax.org/stfb2024/210
https://doi.org/10.1002/alz.13840
https://mouseion.jax.org/context/stfb2024/article/1179/viewcontent/Alzheimer_s_Dementia___2024___Sasner___In_vivo_validation_of_late_onset_Alzheimer_s_disease_genetic_risk_factors.pdf

المؤلفون: Sasner, Michael, Onos, Kristen D, Territo, Paul R, Sukoff Rizzo, Stacey J

المصدر: Faculty Research 2024

مصطلحات موضوعية: JMG, Alzheimer Disease, Humans, Translational Research, Biomedical, Animals, Disease Models, Animal, Biomarkers

وصف الملف: application/pdf

Relation: https://mouseion.jax.org/stfb2024/211; https://mouseion.jax.org/context/stfb2024/article/1178/viewcontent/Alzheimer_s_Dementia___2024___Sasner___Meeting_report_of_the_fifth_annual_workshop_on_Principles_and_Techniques_for.pdf

الاتاحة: https://mouseion.jax.org/stfb2024/211
https://doi.org/10.1002/alz.13742
https://mouseion.jax.org/context/stfb2024/article/1178/viewcontent/Alzheimer_s_Dementia___2024___Sasner___Meeting_report_of_the_fifth_annual_workshop_on_Principles_and_Techniques_for.pdf

المؤلفون: Pandey, Ravi S, Arnold, Mattias, Batra, Richa, Krumsiek, Jan, Kotredes, Kevin P, Garceau, Dylan, Jackson, Harriet M, Sasner, Michael, Howell, Gareth R, Kaddurah-Daouk, Rima, Carter, Gregory W

المصدر: Faculty Research 2024

مصطلحات موضوعية: JGM, JMG, Animals, Alzheimer Disease, Disease Models, Animal, Brain, Mice, Transgenic, Male, Female, Inbred C57BL, Metabolomics, Metabolome, Sex Characteristics, Humans, Apolipoprotein E4

وصف الملف: application/pdf

Relation: https://mouseion.jax.org/stfb2024/156; https://mouseion.jax.org/context/stfb2024/article/1159/viewcontent/Alzheimer_s_Dementia___2024___Pandey___Metabolomics_profiling_reveals_distinct_sex_specific_signatures_in_serum_and.pdf

الاتاحة: https://mouseion.jax.org/stfb2024/156
https://doi.org/10.1002/alz.13851
https://mouseion.jax.org/context/stfb2024/article/1159/viewcontent/Alzheimer_s_Dementia___2024___Pandey___Metabolomics_profiling_reveals_distinct_sex_specific_signatures_in_serum_and.pdf

المؤلفون: Kotredes, Kevin P, Pandey, Ravi S, Persohn, Scott, Elderidge, Kierra, Burton, Charles P, Miner, Ethan W, Haynes, Kathryn A, Santos, Diogo Francisco S, Williams, Sean-Paul, Heaton, Nicholas, Ingraham, Cynthia M, Lloyd, Christopher, Garceau, Dylan, O'Rourke, Rita, Herrick, Sarah, Rangel-Barajas, Claudia, Maharjan, Surendra, Wang, Nian, Sasner, Michael, Lamb, Bruce T, Territo, Paul R, Sukoff Rizzo, Stacey J, Carter, Gregory W, Howell, Gareth R, Oblak, Adrian L

المصدر: Faculty Research 2024

مصطلحات موضوعية: JGM, JMG, Animals, Alzheimer Disease, Disease Models, Animal, Mice, Amyloid beta-Peptides, tau Proteins, Transgenic, Brain, Synapses, Male, Female, Humans

وصف الملف: application/pdf

Relation: https://mouseion.jax.org/stfb2024/161; https://mouseion.jax.org/context/stfb2024/article/1154/viewcontent/Alzheimer_s_Dementia___2024___Kotredes___Characterizing_molecular_and_synaptic_signatures_in_mouse_models_of_late_onset.pdf

الاتاحة: https://mouseion.jax.org/stfb2024/161
https://doi.org/10.1002/alz.13828
https://mouseion.jax.org/context/stfb2024/article/1154/viewcontent/Alzheimer_s_Dementia___2024___Kotredes___Characterizing_molecular_and_synaptic_signatures_in_mouse_models_of_late_onset.pdf

المؤلفون: Benzow, Kellie, Karanjeet, Kul, Oblak, Adrian L., Carter, Gregory W., Sasner, Michael, Koob, Michael D.

المساهمون: Radiology and Imaging Sciences, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Functional sequence variant, Gene‐replacement mouse model, Protective haplotype, Risk haplotype

وصف الملف: application/pdf

Relation: Alzheimer's & Dementia; Benzow K, Karanjeet K, Oblak AL, Carter GW, Sasner M, Koob MD. Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice. Alzheimers Dement. 2024;20(4):3080-3087. doi:10.1002/alz.13730; https://hdl.handle.net/1805/42172

الاتاحة: https://hdl.handle.net/1805/42172

المؤلفون: Oblak, Adrian L, Forner, Stefania, Territo, Paul R, Sasner, Michael, Carter, Gregory W, Howell, Gareth R, Sukoff-Rizzo, Stacey J, Logsdon, Benjamin A, Mangravite, Lara M, Mortazavi, Ali, Baglietto-Vargas, David, Green, Kim N, MacGregor, Grant R, Wood, Marcelo A, Tenner, Andrea J, LaFerla, Frank M, Lamb, Bruce T, and The MODEL‐AD, Consortium

المصدر: Alzheimer's & dementia (New York, N. Y.). 6(1)

مصطلحات موضوعية: and The MODEL‐AD, Consortium, Alzheimer's disease, LOAD, MRI, Open Science, PET, animal models, preclinical, Alzheimers disease

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2dp6h4zr

المؤلفون: De Schepper, Sebastiaan, Ge, Judy Z, Crowley, Gerard, Ferreira, Laís SS, Garceau, Dylan, Toomey, Christina E, Sokolova, Dimitra, Rueda-Carrasco, Javier, Shin, Sun-Hye, Kim, Jung-Seok, Childs, Thomas, Lashley, Tammaryn, Burden, Jemima J, Sasner, Michael, Sala Frigerio, Carlo, Jung, Steffen, Hong, Soyon

المصدر: Nature Neuroscience (2023) (In press).

مصطلحات موضوعية: Alzheimer's disease, Mechanisms of disease, Molecular neuroscience, Neuroimmunology

وصف الملف: application/pdf

Relation: https://discovery.ucl.ac.uk/id/eprint/10164660/1/s41593-023-01257-z.pdf; https://discovery.ucl.ac.uk/id/eprint/10164660/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10164660/1/s41593-023-01257-z.pdf
https://discovery.ucl.ac.uk/id/eprint/10164660/

المؤلفون: Sasner, Michael, Preuss, Christoph, Pandey, Ravi S., Uyar, Asli, Garceau, Dylan, Kotredes, Kevin P., Williams, Harriet, Oblak, Adrian L., Lin, Peter Bor-Chian, Perkins, Bridget, Soni, Disha, Ingraham, Cindy, Lee-Gosselin, Audrey, Lamb, Bruce T., Howell, Gareth R., Carter, Gregory W.

المساهمون: Radiology and Imaging Sciences, School of Medicine

المصدر: PMC

مصطلحات موضوعية: APOE4, Abca7, Alzheimer’s disease, Animal models, Mthfr, Plcg2, Preclinical, Transcriptomic analysis, Trem2

وصف الملف: application/pdf

Relation: Sasner M, Preuss C, Pandey RS, et al. In vivo validation of late-onset Alzheimer's disease genetic risk factors. Preprint. bioRxiv. 2023;2023.12.21.572849. Published 2023 Dec 24. doi:10.1101/2023.12.21.572849; https://hdl.handle.net/1805/40932

الاتاحة: https://hdl.handle.net/1805/40932

المؤلفون: Kotredes, Kevin P., Pandey, Ravi S., Persohn, Scott, Elderidge, Kierra, Burton, Charles P., Miner, Ethan W., Haynes, Kathryn A., Santos, Diogo Francisco S., Williams, Sean-Paul, Heaton, Nicholas, Ingraham, Cynthia M., Lloyd, Christopher, Garceau, Dylan, O’Rourke, Rita, Herrick, Sarah, Rangel-Barajas, Claudia, Maharjan, Surendra, Wang, Nian, Sasner, Michael, Lamb, Bruce T., Territo, Paul R., Sukoff Rizzo, Stacey J., Carter, Gregory W., Howell, Gareth R., Oblak, Adrian L.

المساهمون: Medical and Molecular Genetics, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Alzheimer’s disease, Genetics, High-fat diet, Late-onset Alzheimer’s disease

وصف الملف: application/pdf

Relation: Kotredes KP, Pandey RS, Persohn S, et al. Characterizing Molecular and Synaptic Signatures in mouse models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology. Preprint. bioRxiv. 2023;2023.12.19.571985. Published 2023 Dec 20. doi:10.1101/2023.12.19.571985; https://hdl.handle.net/1805/40867

الاتاحة: https://hdl.handle.net/1805/40867

المؤلفون: Sasner, Michael, Territo, Paul R., Sukoff Rizzo, Stacey J.

المصدر: Alzheimer's & Dementia ; volume 19, issue 11, page 5284-5288 ; ISSN 1552-5260 1552-5279

الاتاحة: http://dx.doi.org/10.1002/alz.13093

المؤلفون: Pandey, Ravi S., Kotredes, Kevin P., Sasner, Michael, Howell, Gareth R., Carter, Gregory W.

المصدر: BMC Genomics ; volume 24, issue 1 ; ISSN 1471-2164

الاتاحة: http://dx.doi.org/10.1186/s12864-023-09280-x
https://link.springer.com/content/pdf/10.1186/s12864-023-09280-x.pdf
https://link.springer.com/article/10.1186/s12864-023-09280-x/fulltext.html

المؤلفون: Lin, Peter Bor-Chian, Persohn, Scott C., Bedwell, Amanda A., Jiang, Lei, Eldridge, Kierra, Speedy, Rachael, Kotredes, Kevin P., Pandey, Ravi S., Williams, Harriet M., Oblak, Adrian L., Sasner, Michael, Howell, Gareth R., Carter, Gregory W., Lamb, Bruce T., Territo, Paul R.

المساهمون: Neurology, School of Medicine

المصدر: Publisher

مصطلحات موضوعية: Alzheimer’s disease (AD), Dementia, Late-Onset AD (LOAD)

وصف الملف: application/pdf

Relation: Alzheimer’s & Dementia; Lin PBC, Persohn SC, Bedwell AA, et al. Cerebral perfusion and glucose metabolism profiling reveal special phenotypes in the hAPOE3, hAPOE4, Trem2 risk, and doubled risks mice. Alzheimer’s & Dementia. 2022;18(S3):e063682. doi:10.1002/alz.063682; https://hdl.handle.net/1805/42858

الاتاحة: https://hdl.handle.net/1805/42858

المؤلفون: Oblak, Adrian L., Kotredes, Kevin P., Pandey, Ravi S., Reagan, Alaina M., Ingraham, Cynthia, Perkins, Bridget, Lloyd, Christopher, Baker, Deborah, Lin, Peter B., Soni, Disha M., Tsai, Andy P., Persohn, Scott A., Bedwell, Amanda A., Eldridge, Kierra, Speedy, Rachael, Meyer, Jill A., Peters, Johnathan S., Figueiredo, Lucas L., Sasner, Michael, Territo, Paul R., Sukoff Rizzo, Stacey J., Carter, Gregory W., Lamb, Bruce T., Howell, Gareth R.

المساهمون: Radiology and Imaging Sciences, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Alzheimer’s disease, Diet, Genetic risk alleles, Obesity, Predisposition, Transcriptomics

وصف الملف: application/pdf

Relation: Frontiers in Aging Neuroscience; Oblak AL, Kotredes KP, Pandey RS, et al. Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice. Front Aging Neurosci. 2022;14:886575. Published 2022 Jun 24. doi:10.3389/fnagi.2022.886575; https://hdl.handle.net/1805/34577

الاتاحة: https://hdl.handle.net/1805/34577

المؤلفون: Oblak, Adrian L., Cope, Zackary A., Quinney, Sara K., Pandey, Ravi S., Biesdorf, Carla, Masters, Andi R., Onos, Kristen D., Haynes, Leslie, Keezer, Kelly J., Meyer, Jill A., Peters, Jonathan S., Persohn, Scott A., Bedwell, Amanda A., Eldridge, Kierra, Speedy, Rachael, Little, Gabriela, Williams, Sean-Paul, Noarbe, Brenda, Obenaus, Andre, Sasner, Michael, Howell, Gareth R., Carter, Gregory W., Williams, Harriet, Lamb, Bruce T., Territo, Paul R., Sukoff Rizzo, Stacey J.

المساهمون: Radiology and Imaging Sciences, School of Medicine

المصدر: PMC

مصطلحات موضوعية: Amyloid, BACE inhibitor, Mouse model, Preclinical testing

وصف الملف: application/pdf

Relation: Alzheimer's & Dementia: Translational Research & Clinical Interventions; Oblak AL, Cope ZA, Quinney SK, et al. Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice. Alzheimers Dement (N Y). 2022;8(1):e12317. Published 2022 Jul 14. doi:10.1002/trc2.12317; https://hdl.handle.net/1805/34422

الاتاحة: https://hdl.handle.net/1805/34422

المؤلفون: Onos, Kristen D., Quinney, Sara K., Jones, David R., Masters, Andrea R., Pandey, Ravi, Keezer, Kelly J., Biesdorf, Carla, Metzger, Ingrid F., Meyers, Jill A., Peters, Johnathon, Persohn, Scott C., McCarthy, Brian P., Bedwell, Amanda A., Figueiredo, Lucas L., Cope, Zackary A., Sasner, Michael, Howell, Gareth R., Williams, Harriet M., Oblak, Adrian L., Lamb, Bruce T., Carter, Gregory W., Rizzo, Stacey J. Sukoff, Territo, Paul R.

المصدر: Alzheimer's & Dementia: Translational Research & Clinical Interventions ; volume 8, issue 1 ; ISSN 2352-8737 2352-8737

الاتاحة: https://doi.org/10.1002/trc2.12329
https://onlinelibrary.wiley.com/doi/pdf/10.1002/trc2.12329
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/trc2.12329

المؤلفون: Foley, Kate E., Diemler, Cory A., Hewes, Amanda A., Garceau, Dylan T., Sasner, Michael, Howell, Gareth R.

المساهمون: National Institute on Aging, National Institute of Child Health and Human Development

المصدر: Alzheimer's & Dementia: Translational Research & Clinical Interventions ; volume 8, issue 1 ; ISSN 2352-8737 2352-8737

الاتاحة: https://doi.org/10.1002/trc2.12308
https://onlinelibrary.wiley.com/doi/pdf/10.1002/trc2.12308
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/trc2.12308

المؤلفون: Foley, Kate E., Hewes, Amanda A., Garceau, Dylan T., Kotredes, Kevin P., Carter, Gregory W., Sasner, Michael, Howell, Gareth R.

المصدر: Frontiers in Aging Neuroscience ; volume 14 ; ISSN 1663-4365

الاتاحة: http://dx.doi.org/10.3389/fnagi.2022.838436
https://www.frontiersin.org/articles/10.3389/fnagi.2022.838436/full

المؤلفون: Kotredes, Kevin P., Oblak, Adrian, Pandey, Ravi S., Lin, Peter Bor-Chian, Garceau, Dylan, Williams, Harriet, Uyar, Asli, O'Rourke, Rita, O'Rourke, Sarah, Ingraham, Cynthia, Bednarczyk, Daria, Belanger, Melisa, Cope, Zackary, Foley, Kate E., Logsdon, Benjamin A., Mangravite, Lara M., Sukoff Rizzo, Stacey J., Territo, Paul R., Carter, Gregory W., Sasner, Michael, Lamb, Bruce T., Howell, Gareth R.

المصدر: Frontiers in Aging Neuroscience ; volume 14 ; ISSN 1663-4365

الاتاحة: http://dx.doi.org/10.3389/fnagi.2022.857628
https://www.frontiersin.org/articles/10.3389/fnagi.2022.857628/full