المؤلفون: Laura Fritzen, Katharina Wienken, Lelia Wagner, Magdalena Kurtyka, Katharina Vogel, Jakob Körbelin, Sascha Weggen, Gert Fricker, Claus U. Pietrzik

المصدر: Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-23 (2024)

مصطلحات موضوعية: Low-density lipoprotein receptor-related protein 1 (LRP1), Blood-brain barrier (BBB), Drug delivery, Liposomes, γ-secretase modulator (GSM), Nanocarrier, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-8118

URL الوصول: https://doaj.org/article/6959b746fc7b4f43abec3dada8978c0c

المؤلفون: Freyja Aichholzer, Hans-Wolfgang Klafki, Isabella Ogorek, Jonathan Vogelgsang, Jens Wiltfang, Norbert Scherbaum, Sascha Weggen, Oliver Wirths

المصدر: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: Alzheimer’s disease, GPNMB, Cerebrospinal fluid, Biomarker, Inflammation, Immunoassay, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1758-9193

URL الوصول: https://doaj.org/article/05f6d351f5384f2c95c03641b6682c2e

المؤلفون: Angelika Sabine Bader, Marius-Uwe Gnädig, Merle Fricke, Luca Büschgens, Lena Josefine Berger, Hans-Wolfgang Klafki, Thomas Meyer, Olaf Jahn, Sascha Weggen, Oliver Wirths

المصدر: Life, Vol 13, Iss 4, p 1053 (2023)

مصطلحات موضوعية: Alzheimer’s disease, amyloid, Abeta, 5XFAD, transgenic mice, plaque load, Science

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2075-1729/13/4/1053; https://doaj.org/toc/2075-1729

URL الوصول: https://doaj.org/article/68237a998a89417498e77aaeb7a0356f

المؤلفون: Melanie Hüttenrauch, Isabella Ogorek, Hans Klafki, Markus Otto, Christine Stadelmann, Sascha Weggen, Jens Wiltfang, Oliver Wirths

المصدر: Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-14 (2018)

مصطلحات موضوعية: Alzheimer’s disease (AD), Glycoprotein nonmetastatic melanoma protein B (GPNMB), Neuroinflammation, Activated microglia, Sporadic AD patients, Transgenic mice, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-018-0612-3; https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/f5c9a902a8144fa4878aa4d1c4c44cdb

المؤلفون: Oliver Wirths, Susanne Walter, Inga Kraus, Hans W. Klafki, Martina Stazi, Timo J. Oberstein, Jorge Ghiso, Jens Wiltfang, Thomas A. Bayer, Sascha Weggen

المصدر: Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-12 (2017)

مصطلحات موضوعية: Alzheimer’s disease, N-truncated Amyloid-β, Immunohistochemistry, Mouse model, Postmortem, 5XFAD, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13195-017-0309-z; https://doaj.org/toc/1758-9193

URL الوصول: https://doaj.org/article/6e0a0a2d6bb24114a8fa3fc6fcb54b8a

المؤلفون: Elaine Waldron, Catherine Heilig, Andrea Schweitzer, Nirupa Nadella, Sebastian Jaeger, Anne M. Martin, Sascha Weggen, Klaudia Brix, Claus U. Pietrzik

المصدر: Neurobiology of Disease, Vol 31, Iss 2, Pp 188-197 (2008)

مصطلحات موضوعية: Low density lipoprotein receptor related protein, Amyloid precursor protein, Trafficing, Secretory pathway, Retention, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996108000739; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/6c536fc471564a85b28407ca26a72aa0

المؤلفون: Nina S Gowert, Lili Donner, Madhumita Chatterjee, Yvonne S Eisele, Seyda T Towhid, Patrick Münzer, Britta Walker, Isabella Ogorek, Oliver Borst, Maria Grandoch, Martin Schaller, Jens W Fischer, Meinrad Gawaz, Sascha Weggen, Florian Lang, Mathias Jucker, Margitta Elvers

المصدر: PLoS ONE, Vol 9, Iss 2, p e90523 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3938776?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/28262559de414f24ab89ec45d0d6c575

المؤلفون: Thorsten Jumpertz, Andreas Rennhack, Julia Ness, Sandra Baches, Claus U Pietrzik, Bruno Bulic, Sascha Weggen

المصدر: PLoS ONE, Vol 7, Iss 1, p e30484 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3253113?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/3237de44653c4eb5867f4043956bf93a

المؤلفون: Markus Hartenfeller, Heiko Zettl, Miriam Walter, Matthias Rupp, Felix Reisen, Ewgenij Proschak, Sascha Weggen, Holger Stark, Gisbert Schneider

المصدر: PLoS Computational Biology, Vol 8, Iss 2, p e1002380 (2012)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3280956?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/f1f6a52b4df74591a77f20b65aa75316

المؤلفون: Freyja Aichholzer (10747646), Hans-Wolfgang Klafki (1815010), Isabella Ogorek (528694), Jonathan Vogelgsang (5696201), Jens Wiltfang (44073), Norbert Scherbaum (84100), Sascha Weggen (185102), Oliver Wirths (10747649)

مصطلحات موضوعية: Biochemistry, Cell Biology, Neuroscience, Immunology, Cancer, Hematology, Information Systems not elsewhere classified, Alzheimer’s disease, GPNMB, Cerebrospinal fluid, Biomarker, Inflammation, Immunoassay

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Evaluation_of_cerebrospinal_fluid_glycoprotein_NMB_GPNMB_as_a_potential_biomarker_for_Alzheimer_s_disease/14538839

الاتاحة: https://doi.org/10.6084/m9.figshare.14538839.v1

المؤلفون: Freyja Aichholzer (10747646), Hans-Wolfgang Klafki (1815010), Isabella Ogorek (528694), Jonathan Vogelgsang (5696201), Jens Wiltfang (44073), Norbert Scherbaum (84100), Sascha Weggen (185102), Oliver Wirths (10747649)

مصطلحات موضوعية: Biochemistry, Cell Biology, Neuroscience, Immunology, Cancer, Hematology, Information Systems not elsewhere classified, Alzheimer’s disease, GPNMB, Cerebrospinal fluid, Biomarker, Inflammation, Immunoassay

Relation: https://figshare.com/articles/journal_contribution/Additional_file_3_of_Evaluation_of_cerebrospinal_fluid_glycoprotein_NMB_GPNMB_as_a_potential_biomarker_for_Alzheimer_s_disease/14538845

الاتاحة: https://doi.org/10.6084/m9.figshare.14538845.v1

المؤلفون: Freyja Aichholzer (10747646), Hans-Wolfgang Klafki (1815010), Isabella Ogorek (528694), Jonathan Vogelgsang (5696201), Jens Wiltfang (44073), Norbert Scherbaum (84100), Sascha Weggen (185102), Oliver Wirths (10747649)

مصطلحات موضوعية: Biochemistry, Cell Biology, Neuroscience, Immunology, Cancer, Hematology, Information Systems not elsewhere classified, Alzheimer’s disease, GPNMB, Cerebrospinal fluid, Biomarker, Inflammation, Immunoassay

Relation: https://figshare.com/articles/journal_contribution/Additional_file_2_of_Evaluation_of_cerebrospinal_fluid_glycoprotein_NMB_GPNMB_as_a_potential_biomarker_for_Alzheimer_s_disease/14538842

الاتاحة: https://doi.org/10.6084/m9.figshare.14538842.v1

المؤلفون: Alexander D. Mazura, Anke Ohler, Steffen E. Storck, Magdalena Kurtyka, Franka Scharfenberg, Sascha Weggen, Christoph Becker-Pauly, Claus U. Pietrzik

مصطلحات موضوعية: Pharmacology, Amyloid beta-Peptides, 610 Medizin, Biological Transport, Cell Biology, Mice, Cellular and Molecular Neuroscience, Blood-Brain Barrier, 610 Medical sciences, Animals, Humans, Molecular Medicine, Proprotein Convertase 9, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78129504a4ccf88509f70e0f7c7ce65e

المؤلفون: Martina Stazi, Sandra Lehmann, M. Sadman Sakib, Tonatiuh Pena-Centeno, Luca Büschgens, Andre Fischer, Sascha Weggen, Oliver Wirths

المصدر: Cellular and Molecular Life Sciences
Cellular and molecular life sciences 79(1), 55 (2021). doi:10.1007/s00018-021-04062-8

مصطلحات موضوعية: Male, Amyloid, Neurogenesis, metabolism [Amyloid beta-Peptides], Plaque, Amyloid, drug effects [Neurogenesis], Cellular and Molecular Neuroscience, Mice, pharmacology [Caffeine], Alzheimer Disease, Caffeine, drug therapy [Plaque, Amyloid], drug therapy [Alzheimer Disease], drug effects [Neurons], pathology [Neurons], Animals, Transgenic mice, ddc:610, Molecular Biology, Cells, Cultured, Pharmacology, Neurons, Behavior, Tg4-42, Amyloid beta-Peptides, RNA sequencing, Cell Biology, 5xFAD, Mice, Inbred C57BL, Molecular Medicine, Female, Original Article, Transcriptome, Alzheimer’s disease, Biomarkers, metabolism [Biomarkers]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2f2df6abc62be2c342c4546e272e27
https://pubmed.ncbi.nlm.nih.gov/34913091

المؤلفون: Liana Marengo, Fred Armbrust, Caroline Schoenherr, Steffen E. Storck, Ulrich Schmitt, Silvia Zampar, Oliver Wirths, Hermann Altmeppen, Markus Glatzel, Christoph Kaether, Sascha Weggen, Christoph Becker-Pauly, Claus U. Pietrzik

المصدر: Cellular and molecular life sciences, 79(3):168

مصطلحات موضوعية: Male, 610 Medizin, Alzheimer’s disease, Meprin β, APP(V717I), Amyloid precursor protein, Truncated Aβ, Cellular and Molecular Neuroscience, Alzheimer Disease, 610 Medical sciences, mental disorders, Glial Fibrillary Acidic Protein, Animals, Humans, Learning, Molecular Biology, Crosses, Genetic, Aged, Pharmacology, Mice, Knockout, Memory Disorders, Amyloid beta-Peptides, Brain, Metalloendopeptidases, Cell Biology, Disease Models, Animal, Astrocytes, Molecular Medicine, Female, Amyloid Precursor Protein Secretases, Peptides, Protein Processing, Post-Translational

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586cebca34fceab1dea3aef42cfd0f8b
https://pubmed.ncbi.nlm.nih.gov/35235058

المؤلفون: Sascha Weggen, David C. Mikles, Parul Goel, Kvido Strisovsky, Isabella Ogorek, Anežka Tichá, Martin Hubálek, Thorsten Jumpertz, Claus U. Pietrzik, Boris Schmidt

المصدر: Bioorganic & Medicinal Chemistry Letters. 28:1417-1422

مصطلحات موضوعية: 0301 basic medicine, Proteases, Serine Proteinase Inhibitors, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Styrenes, Serine, 03 medical and health sciences, Catalytic Domain, Endopeptidases, Drug Discovery, Escherichia coli, medicine, Animals, Chymotrypsin, Drosophila Proteins, Humans, Molecular Biology, Enzyme Assays, Serine protease, Protease, 030102 biochemistry & molecular biology, biology, Benzoxazinones, Chemistry, Escherichia coli Proteins, Rhomboid protease, Rhomboid, Organic Chemistry, Membrane Proteins, Transforming Growth Factor alpha, Benzoxazines, DNA-Binding Proteins, Molecular Docking Simulation, 030104 developmental biology, Docking (molecular), Mutation, biology.protein, Molecular Medicine, Cattle, Drosophila

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b1869639505c4439f662ce7a6cb360
https://doi.org/10.1016/j.bmcl.2018.02.017

المؤلفون: Thorsten Jumpertz, Andreas Rennhack, Julia Ness, Ra Baches, Claus U. Pietrzik, Sascha Weggen

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/97/17/PLoS_One_2012_Jan_6_7(1)_e30484.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.286.9067

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.286.9067

المؤلفون: Sascha Weggen, Melanie Hüttenrauch, Oliver Wirths, Margie Kaufmann, Susanne Walter

المصدر: Molecular Neurobiology. 54:6542-6555

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Pathology, medicine.medical_specialty, Neurology, Neuroscience (miscellaneous), Mice, Transgenic, Stimulation, Environment, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Alzheimer Disease, medicine, Animals, Maze Learning, Pathological, Neprilysin, Environmental enrichment, Amyloid beta-Peptides, Working memory, Brain, medicine.disease, Housing, Animal, Peptide Fragments, Disease Models, Animal, Memory, Short-Term, 030104 developmental biology, Disease Progression, Female, Alzheimer's disease, Psychology, Neuroscience, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce587c8c3354461fb4d9f96f8e04fc94
https://doi.org/10.1007/s12035-016-0167-x

المؤلفون: Anfei Huang, Jörg Timm, Sascha Weggen, Tina Senff, Cassandra Margotta, Haifeng C. Xu, Philipp A. Lang, Jun Huang, Jinping Zhang, Prashant V. Shinde, Aleksandra A. Pandyra, Karl S. Lang, Dieter Häussinger, Thomas E. Willnow

مصطلحات موضوعية: 0301 basic medicine, Cytotoxicity, Immunologic, T-Lymphocytes, Medizin, Biology, CD8-Positive T-Lymphocytes, Lymphocytic Choriomeningitis, Lymphocytic choriomeningitis, Lymphocyte Activation, Antiviral Agents, Virus, 03 medical and health sciences, Mice, 0302 clinical medicine, Progranulins, Transcription (biology), Immunopathology, medicine, Animals, Humans, Lymphocytic choriomeningitis virus, Mice, Knockout, Innate immune system, Cyclin T, Macrophages, General Medicine, medicine.disease, Acquired immune system, Cyclin-Dependent Kinase 9, Granzyme B, Killer Cells, Natural, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, HEK293 Cells, Liver, Virus Diseases, 030220 oncology & carcinogenesis, Immunology, Viral load, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daefd26e4d12c5896396456aad2a3406
https://www.ncbi.nlm.nih.gov/pubmed/31484831

المؤلفون: Klaudia Lepka, Susanne Walter, Carsten Berndt, Isabella Ogorek, Oliver Wirths, Mitko Dimitrov, Jens Wiltfang, Sandra Lehmann, Hermeto Gerber, Christoph Becker-Pauly, Thorsten Jumpertz, Dirk Beher, Silvia Zampar, Steffen E. Storck, Melanie Hüttenrauch, Sascha Weggen, Claus U. Pietrzik, Patrick C. Fraering

المصدر: Acta neuropathologica. 137(2)

مصطلحات موضوعية: 0301 basic medicine, Proteases, Peptide, Plaque, Amyloid, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, 0302 clinical medicine, Alzheimer Disease, Disintegrin, medicine, Amyloid precursor protein, Animals, Humans, chemistry.chemical_classification, Metalloproteinase, Thrombospondin, Amyloid beta-Peptides, biology, Neurodegeneration, Brain, medicine.disease, Peptide Fragments, Cell biology, Disease Models, Animal, Oligodendroglia, 030104 developmental biology, ADAMTS4, HEK293 Cells, chemistry, biology.protein, ADAMTS4 Protein, Neurology (clinical), Amyloid Precursor Protein Secretases, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8212e83ee23e8c4bb76a3029adc2b02
https://pubmed.ncbi.nlm.nih.gov/30426203