المؤلفون: Youssef, Omar, Lahti, Leo, Kokkola, Arto, Karla, Tiina, Tikkanen, Milja, Ehsan, Homa, Carpelan-Holmstrom, Monika, Koskensalo, Selja, Bohling, Tom, Rautelin, Hilpi, Puolakkainen, Pauli, Knuutila, Sakari, Sarhadi, Virinder

المصدر: Digestive Diseases and Sciences. 63(11):2950-2958

مصطلحات موضوعية: Fecal microbiota, Gastrointestinal neoplasms, 16S rRNA gene sequencing

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-370010
https://doi.org/10.1007/s10620-018-5190-5
https://uu.diva-portal.org/smash/get/diva2:1275957/FULLTEXT01.pdf

المؤلفون: Sarhadi, Virinder, Armengol Rosell, Gemma

مصطلحات موضوعية: Cancer biomarkers, Biomolecules, Risk assessment, Diagnostic biomarkers, Predictive biomarkers

وصف الملف: application/pdf

Relation: Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-0255; Biomolecules; Vol. 12, Issue 8 (August 2022), art. 1021; https://ddd.uab.cat/record/265556; urn:10.3390/biom12081021; urn:oai:ddd.uab.cat:265556; urn:scopus_id:85137318192; urn:articleid:2218273Xv12n8p1021; urn:pmid:35892331; urn:pmc-uid:9331210; urn:pmcid:PMC9331210; urn:oai:pubmedcentral.nih.gov:9331210; urn:oai:egreta.uab.cat:publications/8b414950-a4d5-47f3-aa16-189689b022ed

الاتاحة: https://ddd.uab.cat/record/265556

المؤلفون: Sarhadi, Virinder, Mathew, Binu, Kokkola, Arto, Karla, Tiina, Tikkanen, Milja, Rautelin, Hilpi, Lahti, Leo, Puolakkainen, Pauli, Knuutila, Sakari

المصدر: Gut Pathogens. 13(1)

مصطلحات موضوعية: Diffuse gastric adenocarcinoma, Intestinal gastric adenocarcinoma, GIST, Gut microbiota

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-437884
https://doi.org/10.1186/s13099-021-00403-x
https://uu.diva-portal.org/smash/get/diva2:1538971/FULLTEXT01.pdf

المؤلفون: Sarhadi, Virinder, Lahti, Leo, Saberi, Farideh, Youssef, Omar, Kokkola, Arto, Karla, Tiina, Tikkanen, Milja, Rautelin, Hilpi, Puolakkainen, Pauli, Salehi, Rasoul, Knuutila, Sakari

المساهمون: HUS Abdominal Center, Department of Pathology, Faculty of Medicine, University of Helsinki, Medicum, II kirurgian klinikka, Helsinki University Hospital Area, Haartman Institute (-2014)

مصطلحات موضوعية: Biomedicine, Gut microbiota, gene mutations, colorectal cancer, stool DNA, 16S rRNA gene sequencing, FUSOBACTERIUM, ASSOCIATIONS, DIET

وصف الملف: application/pdf

Relation: Sarhadi , V , Lahti , L , Saberi , F , Youssef , O , Kokkola , A , Karla , T , Tikkanen , M , Rautelin , H , Puolakkainen , P , Salehi , R & Knuutila , S 2020 , ' Gut Microbiota and Host Gene Mutations in Colorectal Cancer Patients and Controls of Iranian and Finnish Origin ' , Anticancer Research , vol. 40 , no. 3 , pp. 1325-1334 . https://doi.org/10.21873/anticanres.14074; ORCID: /0000-0002-1827-9156/work/75947064; http://hdl.handle.net/10138/317195; 166a6908-976d-43a8-8fbc-15f723a711d6; 000522732700014

الاتاحة: http://hdl.handle.net/10138/317195

المؤلفون: Maki-Nevala, Satu, Sarhadi, Virinder Kaur, Knuuttila, Aija, Scheinin, Ilari, Ellonen, Pekka, Lagstrom, Sonja, Ronty, Mikko, Kettunen, Eeva, Husgafvel-Pursiainen, Kirsti, Wolff, Henrik, Knuutila, Sakari

المساهمون: Department of Pathology, Medicum, Clinicum, Department of Medicine, Keuhkosairauksien yksikkö, Sakari Knuutila / Principal Investigator, Institute for Molecular Medicine Finland

مصطلحات موضوعية: Asbestos, Mutation, Lung adenocarcinoma, Mesothelioma, Exome sequencing, GENOME-WIDE ASSOCIATION, EMBEDDED TUMOR MATERIAL, PLEURAL MESOTHELIOMA, BAP1 MUTATIONS, CANCER, CARCINOMA, EGFR, KRAS, SUSCEPTIBILITY, SURVIVAL, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: We thank Paivi Tuominen, Jaana Kierikki, Helina Hamalainen, Sauli Savukoski, Tuula Suitiala, Finnish Institute of Occupational Health, and Milja Tikkanen and Tiina Wirtanen, University of Helsinki, for excellent technical assistance. We are also grateful to Ewen MacDonald for the correction of grammar and style. This work was funded by the Finnish Work Environment Fund (no. 112268 to SK; 112269 to HW; 111100 to KHP), Sigrid Juselius Foundation, Cancer Society of Finland (11/13/2013 to SK; 11/12/2014 to KHP).; Maki-Nevala , S , Sarhadi , V K , Knuuttila , A , Scheinin , I , Ellonen , P , Lagstrom , S , Ronty , M , Kettunen , E , Husgafvel-Pursiainen , K , Wolff , H & Knuutila , S 2016 , ' Driver Gene and Novel Mutations in Asbestos-Exposed Lung Adenocarcinoma and Malignant Mesothelioma Detected by Exome Sequencing ' , Lung , vol. 194 , no. 1 , pp. 125-135 . https://doi.org/10.1007/s00408-015-9814-7; ORCID: /0000-0001-6072-0489/work/52863069; http://hdl.handle.net/10138/297141; b22e798d-9cb0-4048-9057-0fe2e2360f29; 84957839117; 000369998400029

الاتاحة: http://hdl.handle.net/10138/297141

المؤلفون: Bao, Jie, Walliander, Margarita, Kovacs, Ferenc, Nagaraj, Ashwini S., Hemmes, Annabrita, Sarhadi, Virinder Kaur, Knuutila, Sakari, Lundin, Johan, Horvath, Peter, Verschuren, Emmy W.

المساهمون: Institute for Molecular Medicine Finland, Lung Cancer Model Systems, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Research Program in Systems Oncology, HUS Abdominal Center, Department of Pathology, Medicum, University Management, Johan Edvard Lundin / Principal Investigator, Research Group Verschuren Emmy

مصطلحات موضوعية: TUMOR EVOLUTION, HETEROGENEITY, MICROENVIRONMENT, TRACKING, PLATFORM, THERAPY, PATHWAY, ORIGIN, DRIVEN, KRAS, Biomedicine, Biochemistry, cell and molecular biology, Cancers

وصف الملف: application/pdf

Relation: We thank the Laboratory Animal Centre for husbandry support, and Kaisa Salmenkivi and Mikko Mayranpaa for pathology consultation. We thank the Digital and Molecular Pathology Unit supported by Helsinki University and Biocenter Finland. The samples/data used for the research were obtained from the Helsinki Biobank. We thank all study participants for their generous participation in Helsinki Biobank. Research was supported by the University of Helsinki Doctoral Programme in Biomedicine (J.B.); Innovative Medicines Initiative Joint Undertaking Grant Agreement No. 115188, the resources of which are composed of a financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies' in-kind contribution (M.W., J.L., and E.W.V.); the LENDULET-BIOMAG Grant (2018-342) and the European Regional Development Funds (GINOP-2.3.2-15-2016-00006, GINOP-2.3.2-15-2016-00026, GINOP-2.3.2-15-2016-00037) (P.H.); and the Academy of Finland grant 307111 (E.W.V.).; Bao , J , Walliander , M , Kovacs , F , Nagaraj , A S , Hemmes , A , Sarhadi , V K , Knuutila , S , Lundin , J , Horvath , P & Verschuren , E W 2019 , ' Spa-RQ : an Image Analysis Tool to Visualise and Quantify Spatial Phenotypes Applied to Non-Small Cell Lung Cancer ' , Scientific Reports , vol. 9 , 17613 . https://doi.org/10.1038/s41598-019-54038-9; ORCID: /0000-0001-5771-9129/work/66034860; ORCID: /0000-0002-1993-7309/work/66035018; ORCID: /0009-0005-5051-9331/work/157594295; http://hdl.handle.net/10138/308110; fb18df10-b6ae-47a8-923b-dae329d690bf; 000498611300002

الاتاحة: http://hdl.handle.net/10138/308110

المؤلفون: Mäki-Nevala, Satu, Valo, Satu, Ristimaki, Ari, Sarhadi, Virinder, Knuutila, Sakari, Nyström, Minna, Renkonen-Sinisalo, Laura, Lepistö, Anna, Mecklin, Jukka-Pekka, Peltomäki, Päivi

المساهمون: Department of Medical and Clinical Genetics, Medicum, University of Helsinki, Department of Pathology, HUSLAB, Genome-Scale Biology (GSB) Research Program, Clinicum, Research Programs Unit, Molecular and Integrative Biosciences Research Programme, Doctoral Programme in Integrative Life Science, Minna Nyström / Principal Investigator, Genetics, Biosciences, Department of Surgery, II kirurgian klinikka, HUS Abdominal Center

مصطلحات موضوعية: Lynch syndrome, Colorectal adenoma, DNA methylation, DNA mismatch repair, UNE-1 methylation, Mutation, Tumotigenesis, Tumor suppressor, MICROSATELLITE INSTABILITY, COLORECTAL ADENOMAS, BRAF MUTATION, COPY NUMBER, CANCER, GENE, DEFICIENCY, PHENOTYPE, TUMORS, HYPOMETHYLATION, Biomedicine, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: We thank the patients contributing to this study. We thank Beatriz Alcala-Repo and Kirsi Pylvanainen for collecting the samples and patient information. Saila Saarinen and Omar Youssef are thanked for laboratory support. The work was funded by the Jane and Aatos Erkko Foundation (MN, J-PM, and PP), Academy of Finland (grant no. 294643) (PP), the Cancer Foundation Finland (J-PM and PP), the Sigrid Juselius Foundation (PP), and HiLIFE (PP). Funding sources had no involvement in the study design, in the collection, analysis, or interpretation of data, in the writing, nor in the decision to submit the paper for publication.; Mäki-Nevala , S , Valo , S , Ristimaki , A , Sarhadi , V , Knuutila , S , Nyström , M , Renkonen-Sinisalo , L , Lepistö , A , Mecklin , J-P & Peltomäki , P 2019 , ' DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression ' , EBioMedicine , vol. 39 , pp. 280-291 . https://doi.org/10.1016/j.ebiom.2018.12.018; ORCID: /0000-0002-5866-4059/work/54150637; ORCID: /0000-0003-0827-0243/work/54151442; ORCID: /0000-0001-8819-2980/work/54151590; http://hdl.handle.net/10138/298910; 2979e9b4-7a48-41c0-a49b-d8cd204a7fd9; 85058577754; 000456677400038

الاتاحة: http://hdl.handle.net/10138/298910

المؤلفون: Ghanbari, Reza, Mosakhani, Neda, Sarhadi, Virinder K., Armengol, Gemma, Nouraee, Nazila, Mohammadkhani, Ashraf, Khorrami, Samaneh, Arefian, Ehsan, Paryan, Mahdi, Malekzadeh, Reza, Knuutila, Sakari

المساهمون: Sakari Knuutila / Principal Investigator, Department of Pathology, Medicum, University of Helsinki

مصطلحات موضوعية: Biomedicine, Cancers

وصف الملف: application/pdf

Relation: Ghanbari , R , Mosakhani , N , Sarhadi , V K , Armengol , G , Nouraee , N , Mohammadkhani , A , Khorrami , S , Arefian , E , Paryan , M , Malekzadeh , R & Knuutila , S 2015 , ' Simultaneous Underexpression of let-7a-5p and let-7f-5p microRNAs in Plasma and Stool Samples from Early Stage Colorectal Carcinoma: Supplementary Issue: Biomarkers for Colon Cancer ' , Biomarkers in Cancer , vol. 7 , no. Suppl 1 , pp. 39–48 . https://doi.org/10.4137/BIC.S25252; RIS: urn:54E11859901C360CDC73F5E5BA6BF3A1; http://hdl.handle.net/10138/232295; cf762a1d-397d-4785-aa1a-9c7f6dc17801

الاتاحة: http://hdl.handle.net/10138/232295

المؤلفون: Martignoni, Guido, Brunelli, Matteo, Segala, Diego, Munari, Enrico, Gobbo, Stefano, Cima, Luca, Borze, Ioana, Wirtanen, Tina, Sarhadi, Virinder Kaur, Atanesyan, Lilit, Savola, Suvi, Barzon, Luisa, Masi, Giulia, Fassan, Matteo, Eble, John N., Bohling, Tom, Cheng, Liang, Delahunt, Brett, Knuutila, Sakari

المساهمون: Sakari Knuutila / Principal Investigator, Department of Pathology, Medicum, Clinicum, HUSLAB, Tom Böhling / Principal Investigator, HUS Abdominal Center

مصطلحات موضوعية: Clear cell papillary renal cell carcinoma, CK7 immunoreactivity, 34 beta E12, CK14 antigen expression, FISH analysis, VHL mutation, chromosome 3p deletion, aCGH, biomarker, HIPPEL-LINDAU GENE, IMMUNOHISTOCHEMICAL ANALYSIS, EPITHELIAL NEOPLASMS, DISTINCT-ENTITY, CHROMOSOME 3P, DISEASE, EMPHASIS, TUMOR, LACKS, CLASSIFICATION, Biomedicine

وصف الملف: application/pdf

Relation: Internal Funding from Department of Pathology and Diagnostics, Anatomic Pathology, University of Verona (GM, MB, FUR 2014) has been used in part for study-related facilities. The authors state there are no conflicts of interest to disclose.; Martignoni , G , Brunelli , M , Segala , D , Munari , E , Gobbo , S , Cima , L , Borze , I , Wirtanen , T , Sarhadi , V K , Atanesyan , L , Savola , S , Barzon , L , Masi , G , Fassan , M , Eble , J N , Bohling , T , Cheng , L , Delahunt , B & Knuutila , S 2017 , ' Validation of 34betaE12 immunoexpression in clear cell papillary renal cell carcinoma as a sensitive biomarker ' , Pathology , vol. 49 , no. 1 , pp. 10-18 . https://doi.org/10.1016/j.pathol.2016.05.014; http://hdl.handle.net/10138/231346; 258c1ee0-7e28-4aff-b62b-a88fddf2e031; 85006427954; 000390798500002

الاتاحة: http://hdl.handle.net/10138/231346

المؤلفون: Youssef, Omar, Sarhadi, Virinder, Ehsan, Homa, Böhling, Tom, Carpelan-Holmström, Monika, Koskensalo, Selja, Puolakkainen, Pauli, Kokkola, Arto, Knuutila, Sakari

المساهمون: Medicum, Department of Pathology, University of Helsinki, HUSLAB, Tom Böhling / Principal Investigator, Clinicum, II kirurgian klinikka, Department of Surgery, Pauli Puolakkainen / Principal Investigator, HUS Abdominal Center, Teachers' Academy

مصطلحات موضوعية: Stool DNA, next-generation sequencing, Mutations, Gastric neoplasia, Colorectal neoplasia, TUMOR-SUPPRESSOR GENE, APC GENE, ADENOMATOUS POLYPOSIS, STROMAL TUMOR, CANCER, ADENOCARCINOMA, CARCINOMA, KRAS, FREQUENT, GROWTH, General medicine, internal medicine and other clinical medicine, Biomedicine, Surgery, anesthesiology, intensive care, radiology

وصف الملف: application/pdf

Relation: Youssef , O , Sarhadi , V , Ehsan , H , Böhling , T , Carpelan-Holmström , M , Koskensalo , S , Puolakkainen , P , Kokkola , A & Knuutila , S 2017 , ' Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing ' , World Journal of Gastroenterology , vol. 23 , no. 47 , pp. 8291-8299 . https://doi.org/10.3748/wjg.v23.i47.8291; ORCID: /0000-0002-1827-9156/work/40380891; http://hdl.handle.net/10138/230818; 4dd005e6-104e-4468-81ee-29f256a6e3d9; 85039798755; 000418241900004

الاتاحة: http://hdl.handle.net/10138/230818

المؤلفون: Youssef, Omar, Knuuttila, Aija, Piirilä, Päivi, Böhling, Tom, Sarhadi, Virinder, Knuutila, Sakari

المساهمون: Medicum, Department of Pathology, University of Helsinki, HUS Comprehensive Cancer Center, Department of Medicine, Clinicum, Keuhkosairauksien yksikkö, Department of Oncology, HUS Heart and Lung Center, Department of Diagnostics and Therapeutics, HUS Medical Imaging Center, HUSLAB, Tom Böhling / Principal Investigator

مصطلحات موضوعية: Cancers

وصف الملف: application/pdf

Relation: Youssef , O , Knuuttila , A , Piirilä , P , Böhling , T , Sarhadi , V & Knuutila , S 2018 , ' Hotspot Mutations Detectable by Next-generation Sequencing in Exhaled Breath Condensates from Patients with Lung Cancer ' , Anticancer Research , vol. 38 , no. 10 , pp. 5627-5634 . https://doi.org/10.21873/anticanres.12897; ORCID: /0000-0002-2535-4409/work/50021704; ORCID: /0000-0002-1827-9156/work/50022918; http://hdl.handle.net/10138/255281; 884fac70-91a9-49bf-aa91-83f4d2bf23f3; 85054099940; 000449965500007

الاتاحة: http://hdl.handle.net/10138/255281

المؤلفون: Sarhadi, Virinder Kaur, Armengol, Gemma

المساهمون: Department of Oral and Maxillofacial Diseases, Helsinki University Hospital Area, HUS Head and Neck Center

مصطلحات موضوعية: EXPRESSION, EXOSOMAL MICRORNAS, CARCINOMA, IDENTIFICATION, cancer biomarkers, risk assessment, PROGNOSTIC BIOMARKER, DIAGNOSTICS, biomolecules, COLORECTAL-CANCER, predictive biomarkers, diagnostic biomarkers, DISCOVERY, METASTASIS, 1182 Biochemistry, cell and molecular biology, RESISTANCE

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1593::84525a18274f09dbbfef81f7901adf63
http://hdl.handle.net/10138/352166

المؤلفون: Mäki-Nevala, Satu, Knuuttila, Aija, Knuutila, Sakari, Sarhadi, Virinder Kaur

المساهمون: Medicum, Department of Pathology, Clinicum, Department of Medicine, Keuhkosairauksien yksikkö

مصطلحات موضوعية: Biomedicine, Cancers

وصف الملف: application/pdf

Relation: Mäki-Nevala , S , Knuuttila , A , Knuutila , S & Sarhadi , V K 2016 , ' Concordant Results of Epidermal Growth Factor Receptor Mutation Detection by Real-Time Polymerase Chain Reaction and Ion Torrent Technology in Non-Small Cell Lung Cancer ' , Journal of Clinical Respiratory Diseases and Care , vol. 2 , no. 1 . https://doi.org/10.4172/2472-1247.1000107; http://hdl.handle.net/10138/174104; f8f1ff00-ad3b-4295-a9bb-73995735e346

الاتاحة: http://hdl.handle.net/10138/174104

المؤلفون: Maki-Nevala, Satu, Sarhadi, Virinder Kaur, Ronty, Mikko, Kettunen, Eeva, Husgafvel-Pursiainen, Kirsti, Wolff, Henrik, Knuuttila, Aija, Knuutila, Sakari

المساهمون: Department of Pathology, Medicum, Clinicum, Department of Medicine, University of Helsinki, Keuhkosairauksien yksikkö

مصطلحات موضوعية: Lung cancer, Non-small cell lung cancer, Mutation, HARBORING BRAF MUTATIONS, RECEPTOR GENE-MUTATIONS, SOMATIC MUTATIONS, EGFR, METAANALYSIS, KRAS, P53, ADENOCARCINOMAS, FEATURES, PERSPECTIVES, Biomedicine, Cancers

وصف الملف: application/pdf

Relation: We thank Milja Tikkanen for the technical and clinical data collection support, and Tiina Wirtanen, Paivi Tuominen, Jaana Kierikki and Helina Hamalainen for the technical support. We are also grateful to Lauri Lehtimaki for helping to handle the data, Leo Lahti for his help with statistical matters and Ewen Mac Donald for language editing. The study was funded by the Finnish Work Environment Fund (no. 115112 for SK, no. 111100 for KHP, no. 112269 for HW), the Sigrid Juselius Foundation, the Cancer Society of Finland, which covered the sequencing costs of this project; and the Finnish Cultural Foundation for Maki-Nevala's personal grant.; Maki-Nevala , S , Sarhadi , V K , Ronty , M , Kettunen , E , Husgafvel-Pursiainen , K , Wolff , H , Knuuttila , A & Knuutila , S 2016 , ' Hot spot mutations in Finnish non-small cell lung cancers ' , Lung Cancer , vol. 99 , pp. 102-110 . https://doi.org/10.1016/j.lungcan.2016.06.024; http://hdl.handle.net/10138/228322; 7e05fb54-aae1-4684-8c7d-9a0ae9501b14; 84978087127; 000384863000018

الاتاحة: http://hdl.handle.net/10138/228322

المؤلفون: Veija, T., Koljonen, V., Bohling, T., Kero, M., Knuutila, S., Sarhadi, Virinder Kaur

المساهمون: Medicum, Department of Pathology, Clinicum, Plastiikkakirurgian yksikkö, HUSLAB, Tom Böhling / Principal Investigator, HUS Abdominal Center

مصطلحات موضوعية: ALK, EZH2, Merkel cell carcinoma, Next-generation sequencing, RNA, Cancers, Biomedicine

وصف الملف: application/pdf

Relation: Veija , T , Koljonen , V , Bohling , T , Kero , M , Knuutila , S & Sarhadi , V K 2017 , ' Aberrant expression of ALK and EZH2 in Merkel cell carcinoma ' , BMC Cancer , vol. 17 , 236 . https://doi.org/10.1186/s12885-017-3233-5; Bibtex: urn:1c2c68b1b36a6760ed0a9044a750b5dc; ORCID: /0000-0003-0398-4829/work/33531841; http://hdl.handle.net/10138/187959; 84c8465f-27cf-45dd-bbd7-5e9ade7a7c51; 85016567248; 000397776600005

الاتاحة: http://hdl.handle.net/10138/187959

المؤلفون: Benard-Slagter, Anne, Zondervan, Ilse, de Groot, Karel, Ghazavi, Farzaneh, Sarhadi, Virinder, Van Vlierberghe, Pieter, De Moerloose, Barbara, Schwab, Claire, Vettenranta, Kim, Harrison, Christine J., Knuutila, Sakari, Schouten, Jan, Lammens, Tim, Savola, Suvi

المساهمون: Medicum, Department of Pathology, University of Helsinki, Children's Hospital, Clinicum, Lastentautien yksikkö, HUS Children and Adolescents, HUS Abdominal Center

مصطلحات موضوعية: CHRONIC LYMPHOCYTIC-LEUKEMIA, IKZF1 DELETION, REARRANGEMENT, HYBRIDIZATION, ABERRATIONS, PROTOCOL, FUSION, Biomedicine, Cancers

وصف الملف: application/pdf

Relation: Supported in part by the Kinderkankerfonds vzw (T.L.), the Research Foundation Flanders (Odysseus; P.V.V.), and Bloodwise (formerly Leukemia and Lymphoma Research, UK; C.S. and C.J.H.).; Benard-Slagter , A , Zondervan , I , de Groot , K , Ghazavi , F , Sarhadi , V , Van Vlierberghe , P , De Moerloose , B , Schwab , C , Vettenranta , K , Harrison , C J , Knuutila , S , Schouten , J , Lammens , T & Savola , S 2017 , ' Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia ' , Journal of Molecular Diagnostics , vol. 19 , no. 5 , pp. 659-672 . https://doi.org/10.1016/j.jmoldx.2017.05.004; http://hdl.handle.net/10138/224610; 0842d3e6-497d-4cb5-912f-2bd390d02a15; 85027707221; 000410464600004

الاتاحة: http://hdl.handle.net/10138/224610

المؤلفون: Veija, Tuukka, Koljonen, Virve, Bohling, Tom, Kero, Mia, Knuutila, Sakari, Sarhadi, Virinder Kaur

المصدر: BMC Cancer ; volume 17, issue 1 ; ISSN 1471-2407

الاتاحة: http://dx.doi.org/10.1186/s12885-017-3233-5
http://link.springer.com/content/pdf/10.1186/s12885-017-3233-5.pdf

المؤلفون: Sammallahti, Heidelinde, Sarhadi, Virinder Kaur, Kokkola, Arto, Ghanbari, Reza, Rezasoltani, Sama, Asadzadeh Aghdaei, Hamid, Puolakkainen, Pauli, Knuutila, Sakari

المساهمون: Medicum, University of Helsinki, Department of Pathology, HUS Abdominal Center, Department of Surgery, Department of Oral and Maxillofacial Diseases, HUS Head and Neck Center, II kirurgian klinikka, Clinicum, Teachers' Academy, Pauli Puolakkainen / Principal Investigator

مصطلحات موضوعية: DOWN-REGULATION, gut microbiota, MICRORNAS, pancreatic cancer, METHYLATION, DUCTAL ADENOCARCINOMA, DNA, DIAGNOSIS, stool screening, K-RAS MUTATIONS, COLORECTAL-CANCER, MICROBIOME, 1182 Biochemistry, cell and molecular biology, non-invasive screening, 3111 Biomedicine, oncogenomics, genomic biomarkers, early diagnosis, GENE-EXPRESSION

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1593::034fdb8e926def99b028c0488283ef7a
http://hdl.handle.net/10138/345145

المؤلفون: Tuononen, Katja, Sarhadi, Virinder Kaur, Wirtanen, Aino, Rönty, Mikko Juhani, Salmenkivi, Kaisa, Knuuttila, Aija, Remes, Satu, Telaranta-Keerie, Aino I., Bloor, Stuart, Ellonen, Pekka, Knuutila, Sakari

المساهمون: Department of Pathology, Haartman Institute (-2014), Clinicum, Department of Medicine, Keuhkosairauksien yksikkö, Institute for Molecular Medicine Finland

مصطلحات موضوعية: ANAPLASTIC LYMPHOMA KINASE, GENE REARRANGEMENT, CANCER, EML4-ALK, ADENOCARCINOMAS, TRANSLOCATIONS, NONSMOKERS, MUTATIONS, GENOMICS, EGFR, Biomedicine, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

Relation: Lab21 is a distributor of the AmoyDx EML4-ALK fusion gene detection kit and Abbott the Vysis LSI ALK Dual Color Break Apart FISH kit. Sakari Knuutila, Kaisa Salmenkivi, and Aija Knuuttila attended advisory board meetings for Pfizer and were sponsored by Pfizer to attend a medical congress. Sakari Knuutila attended advisory board meeting for Abbott Molecular Inc.; Tuononen , K , Sarhadi , V K , Wirtanen , A , Rönty , M J , Salmenkivi , K , Knuuttila , A , Remes , S , Telaranta-Keerie , A I , Bloor , S , Ellonen , P & Knuutila , S 2013 , ' Targeted Resequencing Reveals ALK Fusions in Non-Small Cell Lung Carcinomas Detected by FISH, Immunohistochemistry, and Real-Time RT-PCR: A Comparison of Four Methods ' , BioMed Research International . https://doi.org/10.1155/2013/757490; ORCID: /0000-0001-6072-0489/work/52863063; http://hdl.handle.net/10138/164031; 361bd3bf-3738-4bd7-aa85-27e117cab02f; 84874586164; 000314952200001

الاتاحة: http://hdl.handle.net/10138/164031

المؤلفون: Armengol, Gemma, Sarhadi, Virinder K., Ghanbari, Reza, Doghaei-Moghaddam, Masoud, Ansari, Reza, Sotoudeh, Masoud, Puolakkainen, Pauli, Kokkola, Arto, Malekzadeh, Reza, Knuutila, Sakari

المصدر: The Journal of Molecular Diagnostics ; volume 18, issue 4, page 471-479 ; ISSN 1525-1578

الاتاحة: http://dx.doi.org/10.1016/j.jmoldx.2016.01.008
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