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1Academic Journal
المؤلفون: Michael Grigalunas, Annina Burhop, Sarah Zinken, Axel Pahl, José-Manuel Gally, Niklas Wild, Yannik Mantel, Sonja Sievers, Daniel J. Foley, Rebecca Scheel, Carsten Strohmann, Andrey P. Antonchick, Herbert Waldmann
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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المؤلفون: Herbert Waldmann, Andrey P. Antonchick, Niklas Wild, Sonja Sievers, José-Manuel Gally, Carsten Strohmann, Axel Pahl, Yannik Mantel, Sarah Zinken, Michael Grigalunas, Daniel J. Foley, Rebecca Scheel, Annina Burhop
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communicationsمصطلحات موضوعية: Indoles, Science, Chemical libraries, General Physics and Astronomy, Computational biology, 010402 general chemistry, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, Natural (archaeology), Article, Griseofulvin, Small Molecule Libraries, chemistry.chemical_compound, Fragment (logic), Drug Discovery, Chemical synthesis, Biological evaluation, Biological Products, Multidisciplinary, Natural product, Product design, Quinine, 010405 organic chemistry, Cheminformatics, General Chemistry, Quinidine, Chemical space, humanities, 0104 chemical sciences, chemistry, Morphinans, Chromones, Product (mathematics), Identification (biology)
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المؤلفون: Elizabeth Yihui Ng, Lara Dötsch, Wanjin Hong, Mohammad Akbarzadeh, Sasikala Thavam, Hélène Adihou, CongBao Kang, Sarah Zinken, Sonja Sievers, Axel Pahl, Ajaybabu V. Pobbati, Hacer Karatas, Christine Nowak, Gernot Hahne, Herbert Waldmann, Stéphanie M. Guéret, Malte Metz, Alexandra Friese
المصدر: Journal of Medicinal Chemistry
مصطلحات موضوعية: Models, Molecular, 01 natural sciences, Fluorescence, Article, Small Molecule Libraries, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, Coactivator, Humans, Structure–activity relationship, Sulfhydryl Compounds, Gene, Transcription factor, 030304 developmental biology, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, Drug discovery, Cell growth, Chemistry, Small molecule, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, Pyrones, Molecular Medicine, Transcription Factors, Cysteine
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المؤلفون: Marjorie A. Carnero Corrales, Aliaa Abdelrahman, Yao-Wen Wu, Luca Laraia, Herbert Waldmann, Christa E. Müller, Sarah Zinken, Petra Janning, Muhammad Rafehi, Georgios Konstantinidis
المصدر: Cell Chemical Biology
Carnero Corrales, M A, Zinken, S, Konstantinidis, G, Rafehi, M, Abdelrahman, A, Wu, Y-W, Janning, P, Müller, C E, Laraia, L & Waldmann, H 2021, ' Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin ', Cell Chemical Biology, vol. 28, no. 12, pp. 1750-1757 . https://doi.org/10.1016/j.chembiol.2021.02.017مصطلحات موضوعية: Proteomics, Male, Proteome, Purinergic P2X Receptor Antagonists, Clinical Biochemistry, Biology, 01 natural sciences, Biochemistry, Structure-Activity Relationship, Target identification, Drug Discovery, Autophagy, Tumor Cells, Cultured, Humans, Receptor, Molecular Biology, Pharmacology, Organisk kemi, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Gene Expression Profiling, Purinergic receptor, Organic Chemistry, Cell Membrane, Biochemistry and Molecular Biology, Temperature, Biological chemistry and chemical biology, Small molecule, Thermal proteome profiling, 0104 chemical sciences, Cell biology, Proteome profiling, Membrane protein, Molecular Medicine, Female, Signal transduction, Receptors, Purinergic P2X4, Biokemi och molekylärbiologi
وصف الملف: application/pdf
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المؤلفون: Dale Corkery, Yao-Wen Wu, Luca Laraia, Sarah Zinken, Daniel J. Foley, Herbert Waldmann, Axel Pahl
المصدر: Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Foley, D J, Zinken, S, Corkery, D, Laraia, L, Pahl, A, Wu, Y & Waldmann, H 2020, ' Phenotyping reveals the targets of a pseudo-natural product autophagy inhibitor ', Angewandte Chemie International Edition, vol. 59, no. 30, pp. 12470-12476 . https://doi.org/10.1002/anie.202000364
Foley, D J, Zinken, S, Corkery, D, Laraia, L, Pahl, A, Wu, Y & Waldmann, H 2020, ' Phenotyping reveals the targets of a pseudo-natural product autophagy inhibitor ', Angewandte Chemie, vol. 132, no. 30, pp. 12570-12576 . https://doi.org/10.1002/ange.202000364مصطلحات موضوعية: autophagy, natural products, Chemical biology, chemical biology, Computational biology, 010402 general chemistry, alkaloids, 01 natural sciences, Catalysis, chemistry.chemical_compound, Biosynthesis, Alkaloids | Hot Paper, inhibitors, Humans, Enzyme Inhibitors, Research Articles, Biological Products, Organisk kemi, Natural product, 010405 organic chemistry, Autophagy, Organic Chemistry, General Medicine, General Chemistry, Class III Phosphatidylinositol 3-Kinases, 0104 chemical sciences, 3. Good health, chemistry, Phenotyping, Drug Design, MCF-7 Cells, Pseudo-natural products, Palladium, Research Article
وصف الملف: application/pdf
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المؤلفون: Yao-Wen Wu, Sonja Sievers, Luca Laraia, Sarah Zinken, Daniel J. Foley, Christoph Arenz, Thomas Pinkert, Nadine Kaiser, Herbert Waldmann, Axel Pahl, Petra Janning, Sebastian Müller, Raphaël Rodriguez, Dale Corkery, Guillaume Garivet, Julian Wilke
المصدر: Laraia, L, Garivet, G, Foley, D J, Kaiser, N, Müller, S, Zinken, S, Pinkert, T, Wilke, J, Corkery, D, Pahl, A, Sievers, S, Janning, P, Arenz, C, Wu, Y, Rodriguez, R & Waldmann, H 2020, ' Image-Based Morphological Profiling Identifies a Lysosomotropic, Iron-Sequestering Autophagy Inhibitor ', Angewandte Chemie-International Edition, vol. 59, no. 14, pp. 5721-5729 . https://doi.org/10.1002/anie.201913712
Angewandte Chemie International Edition
Angewandte Chemie (International Ed. in English)مصطلحات موضوعية: autophagy, Cinchona Alkaloids, Iron, Cell- och molekylärbiologi, Computational biology, Biology, 010402 general chemistry, Proteomics, 01 natural sciences, Catalysis, Structure-Activity Relationship, 03 medical and health sciences, proteomics, target identification, Cell Line, Tumor, Lysosome, medicine, Humans, Profiling (information science), Research Articles, 030304 developmental biology, Alternative methods, 0303 health sciences, 010405 organic chemistry, Autophagy, Autophagosomes, Cell Painting, General Chemistry, General Medicine, 0104 chemical sciences, cell painting, Cell and molecular biology, medicine.anatomical_structure, Microscopy, Fluorescence, lysosome, Lysosomes, Reactive Oxygen Species, Image based, Cell and Molecular Biology, Research Article
وصف الملف: application/pdf
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المؤلفون: Andrey P. Antonchick, Roberta Caporaso, Sarah Zinken, Evgeny R. Lukyanenko, Alexander R. Kochnev, Alexander V. Kurkin, Srimanta Manna
المصدر: Chemical Communications. 52:12486-12489
مصطلحات موضوعية: 010405 organic chemistry, Dimethyl sulfoxide, Radical, Metals and Alloys, General Chemistry, 010402 general chemistry, 01 natural sciences, Catalysis, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, Deuterium, chemistry, Reagent, Materials Chemistry, Ceramics and Composites, Organic chemistry
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