المؤلفون: Edward King, Sarah Maxel, Yulai Zhang, Karissa C. Kenney, Youtian Cui, Emma Luu, Justin B. Siegel, Gregory A. Weiss, Ray Luo, Han Li

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/41cd426163c543aaa20d2d073663935b

المؤلفون: Sarah Maxel (8960951), Samer Saleh (11372718), Edward King (1369512), Derek Aspacio (8960954), Linyue Zhang (4857295), Ray Luo (141237), Han Li (10885)

مصطلحات موضوعية: Biochemistry, Genetics, Biotechnology, Evolutionary Biology, Sociology, Computational Biology, Space Science, Biological Sciences not elsewhere classified, random mutagenesis yielded, oxygenase engineering accelerate, escherichia coli <, additional distal mutation, less expensive cofactor, variant chmo dtnpy, wild type afforded, nadh redox balance, consume molecular oxygen, variant chmo dtnp, oxygenase evolution based, wild type, additional evolution, chmo dtnp, cofactor specificity, cofactor contacts, engineer chmo, chmo usage, ∼ 2900, ∼ 1200, valuable oxidation, throughput selection

Relation: https://figshare.com/articles/journal_contribution/Growth-Based_High-Throughput_Selection_for_NADH_Preference_in_an_Oxygen-Dependent_Biocatalyst/16556148

الاتاحة: https://doi.org/10.1021/acssynbio.1c00258.s001

المؤلفون: Sarah Maxel, Linyue Zhang, Edward King, Ana Paula Acosta, Ray Luo, Han Li

المصدر: Catalysts; Volume 10; Issue 8; Pages: 935

مصطلحات موضوعية: cyclohexanone monooxygenase, Acinetobacter sp. NCIMB 9871, Baeyer–Villiger monooxygenase, directed evolution, thermostability, NADPH specificity, redox balance, high-throughput selection

وصف الملف: application/pdf

Relation: Biocatalysis; https://dx.doi.org/10.3390/catal10080935

الاتاحة: https://doi.org/10.3390/catal10080935

المؤلفون: Edward King, Youtian Cui, Derek Aspacio, Frances Nicklen, Linyue Zhang, Sarah Maxel, Ray Luo, Justin B. Siegel, Erick Aitchison, Han Li

المصدر: ACS Catalysis. 12:8582-8592

مصطلحات موضوعية: General Chemistry, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8bf1f28d28c4d31d828e2f64fb39b6c4
https://doi.org/10.1021/acscatal.2c01837

المؤلفون: Sarah Maxel, Han Li, Ray Luo, Edward King, Yulai Zhang

المصدر: ACS Synthetic Biology. 9:3124-3133

مصطلحات موضوعية: 0106 biological sciences, 0303 health sciences, Oxygenase, Chemistry, Biomedical Engineering, General Medicine, Computational biology, medicine.disease_cause, Directed evolution, 01 natural sciences, Biochemistry, Genetics and Molecular Biology (miscellaneous), Redox, 03 medical and health sciences, In vivo, 010608 biotechnology, medicine, Selection (genetic algorithm), Oxidative stress, Function (biology), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d1c9d8f652ca6268de4c43c277f69ec3
https://doi.org/10.1021/acssynbio.0c00380

المؤلفون: Justin B. Siegel, Linyue Zhang, Edward King, Sarah Maxel, William B. Black, Han Li, Wai Shun Mak, Youtian Cui, Bonnie Fong, Alicia Sanchez Martinez

المصدر: Nat Chem Biol

مصطلحات موضوعية: Chromatography, Gas, Protein Conformation, Ralstonia, Protein Engineering, Redox, Article, Cofactor, 03 medical and health sciences, chemistry.chemical_compound, Glucose dehydrogenase, Escherichia coli, Molecular Biology, Nicotinamide Mononucleotide, 030304 developmental biology, Nicotinamide mononucleotide, 0303 health sciences, biology, Cyclohexanones, Pseudomonas putida, 030302 biochemistry & molecular biology, Cell Biology, NAD, Carbon, Kinetics, Metabolic pathway, chemistry, Biochemistry, Biocatalysis, biology.protein, NAD+ kinase, Oxidation-Reduction, Flux (metabolism), NADP, Software, Nicotinamide adenine dinucleotide phosphate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1014f6749e77c3da09f2583740939c
https://doi.org/10.1038/s41589-019-0402-7

المؤلفون: Ana Paula Acosta, Sarah Maxel, Linyue Zhang, Han Li, Ray Luo, Edward King

المصدر: Catalysts, Vol 10, Iss 935, p 935 (2020)
Catalysts
Volume 10
Issue 8

مصطلحات موضوعية: 0301 basic medicine, Oxygenase, Cyclohexanone, high-throughput selection, Baeyer–Villiger monooxygenase, medicine.disease_cause, lcsh:Chemical technology, 01 natural sciences, Acinetobacter sp. NCIMB 9871, Catalysis, redox balance, lcsh:Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Stereospecificity, medicine, NADPH specificity, lcsh:TP1-1185, Physical and Theoretical Chemistry, directed evolution, Escherichia coli, Thermostability, 010405 organic chemistry, Rational design, Substrate (chemistry), Directed evolution, Combinatorial chemistry, thermostability, 0104 chemical sciences, 030104 developmental biology, chemistry, lcsh:QD1-999, cyclohexanone monooxygenase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee8456229073d8c992709a47a30c69d
https://www.mdpi.com/2073-4344/10/8/935

المؤلفون: Han Li, Edward King, Sarah Maxel

المصدر: Curr Opin Biotechnol

مصطلحات موضوعية: 0106 biological sciences, Niacinamide, Biomedical Engineering, Design elements and principles, Bioengineering, Computational biology, Nicotinamide adenine dinucleotide, 01 natural sciences, Cofactor, Article, 03 medical and health sciences, chemistry.chemical_compound, 010608 biotechnology, Biomanufacturing, Industrial Development, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Nicotinamide, Chemistry, NAD, Enzyme, biology.protein, NAD+ kinase, NADP, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9548f2128d18cd67a216fb84f593dc
https://pubmed.ncbi.nlm.nih.gov/32956903

المؤلفون: Derek Aspacio, Ray Luo, Ana Paula Acosta, Sarah Maxel, Linyue Zhang, Edward King, Han Li

مصطلحات موضوعية: chemistry.chemical_classification, Oxygenase, Enzyme, Molecular model, chemistry, Biochemistry, biology, biology.protein, Wild type, Monooxygenase, Directed evolution, Cofactor, Thermostability

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::64a4c2d986c08519a769e50c7dcb4de7
https://doi.org/10.1101/2020.05.22.111575

المؤلفون: Linyue Zhang, Sarah Maxel, Ana Paula Acosta, Edward King, Derek Aspacio, Han Li

المصدر: ACS Catal

مصطلحات موضوعية: Oxygenase, Computational biology, 010402 general chemistry, medicine.disease_cause, Redox, 01 natural sciences, Catalysis, Article, 03 medical and health sciences, medicine, Escherichia coli, Selection (genetic algorithm), 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, 010405 organic chemistry, Pseudomonas, Active site, General Chemistry, Directed evolution, biology.organism_classification, 0104 chemical sciences, Enzyme, Biochemistry, chemistry, Hydroxybenzoate, biology.protein, Sequence space (evolution)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413a97fc5451f057a08f13d925bddaed
https://doi.org/10.1101/2020.05.11.088898