المؤلفون: Valentina Stock, Rebecca Hofer, Franziska Lochmann, Vera Spanke, Klaus R. Liedl, Jakob Troppmair, Thierry Langer, Hubert Gstach, Christian Dank, Chris A. Mayhew, Sarah Kammerer, Veronika Ruzsanyi

المصدر: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

مصطلحات موضوعية: Breath test, CYP3A4, HepG2, Tolterodine, Acetone, Volatile biomarkers, Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/c331948a591b4c32beff2a1a76ba3a01

المؤلفون: Anne Krüger-Genge, Susanne Köhler, Markus Laube, Vanessa Haileka, Sandy Lemm, Karolina Majchrzak, Sarah Kammerer, Christian Schulz, Joachim Storsberg, Jens Pietzsch, Jan-Heiner Küpper, Friedrich Jung

المصدر: Cells, Vol 12, Iss 15, p 1965 (2023)

مصطلحات موضوعية: cancer, cyclophosphamide, human umbilical vein endothelial cells, HUVEC, liver, cytochrome P450 enzymes (CYP), Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/15/1965; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/83964bfc5dd142859c27ae12253ad052

المؤلفون: Susanne Steinbrecht, Jan Kiebist, Rosalie König, Markus Thiessen, Kai-Uwe Schmidtke, Sarah Kammerer, Jan-Heiner Küpper, Katrin Scheibner

المصدر: AMB Express, Vol 10, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Biocatalysis, Cyclophosphamide, Human drug metabolites, Peroxygenase, Toxicity, Biotechnology, TP248.13-248.65, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13568-020-01064-w; https://doaj.org/toc/2191-0855

URL الوصول: https://doaj.org/article/02be8937c7c9421ca3f00981bdaa4085

المؤلفون: Steffen Braune, Anne Krüger-Genge, Sarah Kammerer, Friedrich Jung, Jan-Heiner Küpper

المصدر: Life, Vol 11, Iss 2, p 91 (2021)

مصطلحات موضوعية: phycocyanin, Arthrospira platensis, cancer, tumor, drug, in vitro, Science

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2075-1729/11/2/91; https://doaj.org/toc/2075-1729

URL الوصول: https://doaj.org/article/66c4b312febc407da383a5d43ffb5681

المؤلفون: Dimitrios Vagiannis, Youssif Budagaga, Anselm Morell, Yu Zhang, Eva Novotná, Adam Skarka, Sarah Kammerer, Jan-Heiner Küpper, Ivo Hanke, Tomáš Rozkoš, Jakub Hofman

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 21; Pages: 11936

مصطلحات موضوعية: tepotinib, non-small cell lung cancer, multidrug resistance, drug interaction, ABC transporter, cytochrome P450

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms222111936

الاتاحة: https://doi.org/10.3390/ijms222111936

المؤلفون: Sarah Kammerer

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 19; Pages: 10214

مصطلحات موضوعية: hepatocytes, HepG2, HepaRG, upcyte hepatocytes, 3D culture systems, primary hepatic function, toxicology, spheroids, perfused bioreactors, liver-on-a-chip

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biology; https://dx.doi.org/10.3390/ijms221910214

الاتاحة: https://doi.org/10.3390/ijms221910214

المؤلفون: Dimitrios Vagiannis, Eva Novotna, Adam Skarka, Sarah Kammerer, Jan-Heiner Küpper, Si Chen, Lei Guo, Frantisek Staud, Jakub Hofman

المصدر: Cancers; Volume 12; Issue 4; Pages: 813

مصطلحات موضوعية: ensartinib, cancer, multidrug resistance, drug-drug interaction, ABC transporter, cytochrome P450

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers12040813

الاتاحة: https://doi.org/10.3390/cancers12040813

المؤلفون: Nadine Katzenberger, S. Steinbrecht, Sarah Kammerer, Jan-Heiner Küpper, Nadine Pfeifer, Christian Schulz, Natalie Herzog

المساهمون: Publica

المصدر: Toxicology Letters. 319:155-159

مصطلحات موضوعية: Hepatoblastoma, 0301 basic medicine, Aflatoxin, Aflatoxin B1, Genetic Vectors, Cell, Toxicology, 03 medical and health sciences, Mycoplasma, 0302 clinical medicine, Cytochrome P-450 CYP1A2, Cell Line, Tumor, medicine, Humans, Vector (molecular biology), biology, Chemistry, Lentivirus, Liver Neoplasms, CYP1A2, Phenacetin, Cytochrome P450, General Medicine, medicine.disease, biology.organism_classification, DNA Fingerprinting, Molecular biology, 030104 developmental biology, medicine.anatomical_structure, Liver, biology.protein, 030217 neurology & neurosurgery, Plasmids, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da4f789f82c00634539edfd055eeafe
https://doi.org/10.1016/j.toxlet.2019.11.006

المؤلفون: S. Steinbrecht, Sarah Kammerer, Jan-Heiner Küpper

المصدر: Journal of Cellular Biotechnology. 5:55-64

مصطلحات موضوعية: Cytochrome p450 enzyme, Biochemistry, law, Chemistry, Hepg2 cells, Recombinant DNA, Molecular Biology, Applied Microbiology and Biotechnology, In vitro, Biotechnology, law.invention

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::944716f4cc447845db612df51a84add3
https://doi.org/10.3233/jcb-189013

المؤلفون: Steffen, Braune, Anne, Krüger-Genge, Sarah, Kammerer, Friedrich, Jung, Jan-Heiner, Küpper

المصدر: Life

مصطلحات موضوعية: tumor, in vivo, Arthrospira platensis, cancer, drug, in vitro, Review, phycocyanin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8fdde4b51fce5842376732fa809f7771
https://pubmed.ncbi.nlm.nih.gov/33513794

المؤلفون: Sarah Kammerer, Jan-Heiner Küpper

المصدر: Journal of Cellular Biotechnology. 3:85-93

مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, Human hepatocyte, 030104 developmental biology, Chemistry, In vitro toxicology, Molecular Biology, Applied Microbiology and Biotechnology, Biotechnology, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f366708e9bcc9fe80b87ed1ca0371c48
https://doi.org/10.3233/jcb-179012

المؤلفون: Dimitrios Vagiannis, Yu Zhang, Youssif Budagaga, Eva Novotna, Adam Skarka, Sarah Kammerer, Jan-Heiner Küpper, Jakub Hofman

المصدر: Toxicology and Applied Pharmacology. 434:115823

مصطلحات موضوعية: Models, Molecular, Pharmacology, Dose-Response Relationship, Drug, Protein Conformation, Azepines, Toxicology, Cell Line, Molecular Docking Simulation, Dogs, Pyrimidines, Cytochrome P-450 Enzyme System, Gene Expression Regulation, Catalytic Domain, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Humans, Drug Interactions, ATP Binding Cassette Transporter, Subfamily B, Member 1, Multidrug Resistance-Associated Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701bfec3784c6a3e11197855e8158b5f
https://doi.org/10.1016/j.taap.2021.115823

المؤلفون: Stefan Rödiger, Sarah Kammerer, Kurt J.G. Schmailzl, Jan-Heiner Küpper, Friedrich Jung

المصدر: Journal of Cellular Biotechnology. 4:1-3

مصطلحات موضوعية: Molecular Biology, Applied Microbiology and Biotechnology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f723e392d745c48cf6b8600861c6e39
https://doi.org/10.3233/jcb-189001

المؤلفون: Simona Sucha, Jan-Heiner Küpper, Dimitrios Vagiannis, Frantisek Staud, Jakub Hofman, Lei Guo, Si Chen, Ales Sorf, Martina Ceckova, Sarah Kammerer

المصدر: Molecular pharmaceutics. 16(11)

مصطلحات موضوعية: ATP Binding Cassette Transporter, Subfamily B, CYP2B6, Abcg2, medicine.drug_class, Pharmaceutical Science, ATP-binding cassette transporter, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Tyrosine-kinase inhibitor, Cell Line, Madin Darby Canine Kidney Cells, 03 medical and health sciences, 0302 clinical medicine, Dogs, Cytochrome P-450 Enzyme System, In vivo, Drug Discovery, medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Drug Interactions, Biotransformation, Alanine, biology, Chemistry, Triazines, 021001 nanoscience & nanotechnology, Drug Resistance, Multiple, Neoplasm Proteins, Multiple drug resistance, Drug Resistance, Neoplasm, biology.protein, ABCC1, Molecular Medicine, Efflux, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffec70607c84ef2bce9d502aae7850c
https://pubmed.ncbi.nlm.nih.gov/31633365

المؤلفون: Martina Ceckova, Simona Sucha, Ales Sorf, Dimitrios Vagiannis, Sarah Kammerer, Jan-Heiner Küpper, Frantisek Staud, Eva Novotna, Jakub Hofman

المصدر: Drug metabolism and disposition: the biological fate of chemicals. 47(7)

مصطلحات موضوعية: Alectinib, CYP2B6, Abcg2, medicine.drug_class, Carbazoles, Pharmaceutical Science, ATP-binding cassette transporter, Pharmacology, 030226 pharmacology & pharmacy, Tyrosine-kinase inhibitor, Madin Darby Canine Kidney Cells, 03 medical and health sciences, 0302 clinical medicine, Dogs, Cytochrome P-450 Enzyme System, Piperidines, medicine, Animals, Humans, Protein Kinase Inhibitors, Biotransformation, CYP3A4, biology, Chemistry, Drug Resistance, Multiple, Multiple drug resistance, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, biology.protein, ABCC1, ATP-Binding Cassette Transporters

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f793e9f882454bbfe3fc914b96cdc9da
https://pubmed.ncbi.nlm.nih.gov/31068367

المؤلفون: Natalie Herzog, Friedrich Jung, Jan-Heiner Küpper, Anne Krüger-Genge, S. Steinbrecht, Kai-Uwe Schmidtke, Katrin Scheibner, Sarah Kammerer, Rosalie König

المصدر: Toxicology. 412

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Programmed cell death, DNA damage, Chemistry, Cell, Clone (cell biology), Hep G2 Cells, Toxicology, Molecular biology, Cytochrome P-450 CYP2C19, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Enzyme, Cell culture, medicine, Cytochrome P-450 CYP3A, Humans, Viability assay, Acrolein, Cytotoxicity, Cyclophosphamide, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dd374f184acbf777eb991648686cdc
https://pubmed.ncbi.nlm.nih.gov/30500380

المؤلفون: Eva Herrmann, Christian Senft, Sae-Yeon Won, Volker Seifert, Nazife Dinc, Sarah Kammerer, Jasmin Hager, Gerhard Marquardt, Johanna Quick-Weller

المصدر: Clinical neurology and neurosurgery. 174

مصطلحات موضوعية: Male, medicine.medical_specialty, Stereotactic biopsy, Resection, 03 medical and health sciences, 0302 clinical medicine, Quality of life, medicine, Clinical endpoint, Overall survival, Humans, Progression-free survival, Aged, Retrospective Studies, Aged, 80 and over, medicine.diagnostic_test, business.industry, Brain Neoplasms, Recurrent glioblastoma, General Medicine, medicine.disease, Surgery, Survival Rate, 030220 oncology & carcinogenesis, Female, Neurology (clinical), Neoplasm Recurrence, Local, business, Glioblastoma, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d5e961a10ec1ef2b2bf9386dbc89e7
https://pubmed.ncbi.nlm.nih.gov/30195896

المؤلفون: C. Philidet, A. Krüger-Genge, Andreas Lendlein, F. Jung, Sarah Kammerer, Jan-Heiner Küpper, R. Rangarajan, S. Braune, S. Lau

المصدر: Lau, S.; Rangarajan, R.; Philidet, C.; Krüger-Genge, A.; Braune, S.; Kammerer, S.; Küpper, J.; Lendlein, A.; Jung, F.: Effects of acrolein in comparison to its prodrug cyclophosphamide on human primary endothelial cells in vitro. In: Toxicology in Vitro. Vol. 62 (2020) 104685. (DOI: /10.1016/j.tiv.2019.104685)

مصطلحات موضوعية: 0301 basic medicine, Cyclophosphamide, Cell Survival, Thromboxane, Primary Cell Culture, Prostacyclin, Pharmacology, Toxicology, Umbilical vein, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Lactate dehydrogenase, von Willebrand Factor, Cell Adhesion, Human Umbilical Vein Endothelial Cells, medicine, Humans, Prodrugs, Viability assay, Acrolein, Antineoplastic Agents, Alkylating, L-Lactate Dehydrogenase, Endothelial Cells, Thromboxanes, General Medicine, Epoprostenol, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, cardiovascular system, Cell activation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66bb0e4b486dcb07dac7520811960cbf
https://doi.org/10.1016/j.tiv.2019.104685

المؤلفون: Marjon Al, Durga M.S.H. Chandrupatla, Elisa Giovannetti, Willem F. Lems, David Krige, Richard J. Honeywell, George L. Scheffer, Rene P.J. Musters, Sarah Kammerer, Pieternella A. Kramer, Hans W.M. Niessen, Yehuda G. Assaraf, Jacqueline Cloos, Sue Ellen Verbrugge, Rik J. Scheper, Tanja D. de Gruijl, Gert J. Ossenkoppele, Godefridus J. Peters, Tom O'Toole, Gerrit Jansen

المساهمون: Rheumatology, CCA - Target Discovery & Preclinial Therapy Development, Medical oncology laboratory, Physiology, ICaR - Ischemia and repair, Molecular cell biology and Immunology, Pathology, Cardio-thoracic surgery, Hematology laboratory, Hematology

المصدر: Oncotarget, 7(5), 5240-5257. Impact Journals
Verbrugge, C, Al, M, Assaraf, Y G, Kammerer, S, Chandrupatla, D M S H, Honeywell, R J, Musters, R P J, Giovannetti, E, O'Toole, T, Scheffer, G L, Krige, D, de Gruijl, T D, Niessen, J, Lems, W F, Kramer, P A, Scheper, R J, Cloos, J, Ossenkoppele, G J, Peters, G J & Jansen, G 2016, ' Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR ', Oncotarget, vol. 7, no. 5, pp. 5240-5257 .
Oncotarget

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Carboxylesterase 1, lipid droplets, Down-Regulation, Apoptosis, Drug resistance, Biology, Aminopeptidases, 03 medical and health sciences, Lipid droplet, Humans, Prodrugs, Phosphorylation, Protein kinase B, PI3K/AKT/mTOR pathway, aminopeptidase, rapamycin, TOR Serine-Threonine Kinases, Myeloid leukemia, Prodrug, carboxylesterase, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, Immunology, Cancer research, mTOR, Carboxylic Ester Hydrolases, Proto-Oncogene Proteins c-akt, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7132bdaf997b210e31250e4286fad5
https://research.vumc.nl/en/publications/3425ff65-1311-4b6c-9704-8ba13f92b7ea

المؤلفون: Florentia Peintinger, Peter Regitnig, Amin El-Heliebi, Simin Rezania, Thomas Bauernhofer, Martin Pichler, Wolfgang Schreibmayer, Daniela Schwarzenbacher, Verena Stiegelbauer, Stephan W Jahn, Dieter Platzer, Sarah Kammerer, H Fiegl, Hubert Hackl, Armin Sokolowski, Gerald Hoefler

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Pathology, estrogen receptor positive breast cancer, Receptor, ErbB-2, Estrogen receptor, Breast Neoplasms, Cohort Studies, 03 medical and health sciences, Breast cancer, KCNJ3, Predictive Value of Tests, Internal medicine, medicine, Biomarkers, Tumor, Humans, ddc:610, Survival analysis, biology, business.industry, Age Factors, Cancer, Histology, Periodontology, Middle Aged, medicine.disease, Prognosis, Survival Analysis, 3. Good health, Up-Regulation, Gene Expression Regulation, Neoplastic, 030104 developmental biology, G Protein-Coupled Inwardly-Rectifying Potassium Channels, GIRK1, Lymphatic Metastasis, biology.protein, Biomarker (medicine), biomarker, Female, business, RNA in situ hybridization, Research Paper

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cc3c0165d32f3e5e0d0013fb464b83
https://opus.bibliothek.uni-augsburg.de/opus4/files/102833/oncotarget-v7i51-13224.pdf