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1Academic Journal
المؤلفون: Samuel Y. Ng, Noriaki Yoshida, Amanda L. Christie, Mahmoud Ghandi, Neekesh V. Dharia, Joshua Dempster, Mark Murakami, Kay Shigemori, Sara N. Morrow, Alexandria Van Scoyk, Nicolas A. Cordero, Kristen E. Stevenson, Maneka Puligandla, Brian Haas, Christopher Lo, Robin Meyers, Galen Gao, Andrew Cherniack, Abner Louissaint, Valentina Nardi, Aaron R. Thorner, Henry Long, Xintao Qiu, Elizabeth A. Morgan, David M. Dorfman, Danilo Fiore, Julie Jang, Alan L. Epstein, Ahmet Dogan, Yanming Zhang, Steven M. Horwitz, Eric D. Jacobsen, Solimar Santiago, Jian-Guo Ren, Vincent Guerlavais, D. Allen Annis, Manuel Aivado, Mansoor N. Saleh, Amitkumar Mehta, Aviad Tsherniak, David Root, Francisca Vazquez, William C. Hahn, Giorgio Inghirami, Jon C. Aster, David M. Weinstock, Raphael Koch
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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المؤلفون: Francisco Vega, Kristen L Jones, Sara N. Morrow, Michael T. Hemann, Yunpeng Liu, Amanda L. Christie, Olivia Plana, Quang-Dé Nguyen, Jon C. Aster, Jeffrey W. Craig, Alex K. Shalek, Elizabeth A. Morgan, Alexandria Van Scoyk, Huiyun Liu, Kellie E. Kolb, David M. Weinstock, Kay Shigemori, Kristopher A. Sarosiek, Chen Lossos, Cameron Fraser, Kristen E. Stevenson, Sanjay M. Prakadan, Christian P. Pallasch, Rebecca Modiste
المصدر: PMC
مصطلحات موضوعية: 0301 basic medicine, Alkylating Agents, Lymphoma, B-Cell, Cyclophosphamide, Phagocytosis, Syk, Mice, SCID, Mice, Random Allocation, 03 medical and health sciences, 0302 clinical medicine, Bone Marrow, Mice, Inbred NOD, Cell Line, Tumor, medicine, Animals, Humans, Macrophage, Alemtuzumab, Dose-Response Relationship, Drug, biology, Chemistry, Macrophages, Antibodies, Monoclonal, Endoplasmic Reticulum Stress, medicine.disease, Xenograft Model Antitumor Assays, Lymphoma, Vascular endothelial growth factor A, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Bone marrow, Antibody, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Joshua M. Dempster, D. Allen Annis, Neekesh V. Dharia, William C. Hahn, Xintao Qiu, Brian J. Haas, Julie Jang, Kay Shigemori, Giorgio Inghirami, Ahmet Dogan, Sara N. Morrow, Eric D. Jacobsen, Andrew D. Cherniack, Aviad Tsherniak, Jian-Guo Ren, Noriaki Yoshida, Mark A. Murakami, Aaron R. Thorner, David M. Weinstock, Manuel Aivado, Amanda L. Christie, Nicolas A. Cordero, Vincent Guerlavais, Abner Louissaint, Robin M. Meyers, Raphael Koch, Alan L. Epstein, Yanming Zhang, Maneka Puligandla, Mahmoud Ghandi, David E. Root, Elizabeth A. Morgan, Mansoor N. Saleh, Samuel Y. Ng, Danilo Fiore, Jon C. Aster, Alexandria Van Scoyk, Valentina Nardi, Henry W. Long, David M. Dorfman, Amitkumar Mehta, Steven M. Horwitz, Solimar Santiago, Kristen E. Stevenson, Francisca Vazquez, Galen F. Gao, Christopher Lo
المساهمون: Ng, S. Y., Yoshida, N., Christie, A. L., Ghandi, M., Dharia, N. V., Dempster, J., Murakami, M., Shigemori, K., Morrow, S. N., Van Scoyk, A., Cordero, N. A., Stevenson, K. E., Puligandla, M., Haas, B., Lo, C., Meyers, R., Gao, G., Cherniack, A., Louissaint, A., Nardi, V., Thorner, A. R., Long, H., Qiu, X., Morgan, E. A., Dorfman, D. M., Fiore, D., Jang, J., Epstein, A. L., Dogan, A., Zhang, Y., Horwitz, S. M., Jacobsen, E. D., Santiago, S., Ren, J. -G., Guerlavais, V., Annis, D. A., Aivado, M., Saleh, M. N., Mehta, A., Tsherniak, A., Root, D., Vazquez, F., Hahn, W. C., Inghirami, G., Aster, J. C., Weinstock, D. M., Koch, R.
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Myeloid, MDMX, Cell, Drug Evaluation, Preclinical, General Physics and Astronomy, Cell Cycle Proteins, Whole Exome Sequencing, Romidepsin, Antineoplastic Agent, Mice, Depsipeptides, Cell Cycle Protein, Imidazoline, Medicine, lcsh:Science, Depsipeptide, Nuclear Protein, Proto-Oncogene Protein, Multidisciplinary, biology, Remission Induction, Nuclear Proteins, Proto-Oncogene Proteins c-mdm2, 3. Good health, Gene Expression Regulation, Neoplastic, Lymphoma, Extranodal NK-T-Cell, medicine.anatomical_structure, Peptide, Mdm2, Human, medicine.drug, Protein Binding, Signal Transduction, Xenograft Model Antitumor Assay, Science, Antineoplastic Agents, Lymphoma, T-Cell, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Ikaros Transcription Factor, In vivo, Proto-Oncogene Proteins, Exome Sequencing, Animals, Humans, Imidazolines, Animal, business.industry, Complete remission, General Chemistry, Janus Kinase 2, medicine.disease, Xenograft Model Antitumor Assays, Lymphoma, 030104 developmental biology, biology.protein, Cancer research, lcsh:Q, Tumor Suppressor Protein p53, business, Peptides
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المؤلفون: Alexandria Van Scoyk, Lisa Drew, Justin Cidado, Sara N. Morrow, Anthony Letai, Wenchao Wu, Deborah Plana, Raphael Koch, Jennifer L. Crombie, David M. Weinstock, J. Paul Secrist, Amanda L. Christie, Elizabeth Brem, Adam C. Palmer, Kay Shigemori, Alwin Schuller
المصدر: Blood. 133(6)
مصطلحات موضوعية: Vincristine, Macrocyclic Compounds, Immunology, Mice, SCID, CHOP, Lymphoma, T-Cell, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, In vivo, Mice, Inbred NOD, Cell Line, Tumor, Proto-Oncogene Proteins, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Tumor Cells, Cultured, Medicine, Animals, Humans, MCL1, Molecular Targeted Therapy, Cyclophosphamide, 030304 developmental biology, 0303 health sciences, Lymphoid Neoplasia, Navitoclax, business.industry, Venetoclax, Cell Biology, Hematology, medicine.disease, Chemotherapy regimen, Xenograft Model Antitumor Assays, Peptide Fragments, 3. Good health, Lymphoma, chemistry, Doxorubicin, 030220 oncology & carcinogenesis, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Prednisone, biological phenomena, cell phenomena, and immunity, business, Biomarkers, medicine.drug
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المؤلفون: Zhengnian Li, Katherine A. Donovan, Sara N. Morrow, Eric S. Fischer, Dennis Dobrovolsky, Eric S. Wang, Tyler B. Faust, Nathanael S. Gray, David M. Weinstock, Guang Yang, Catharine S. Leahy, Steven P. Treon, Radosław P. Nowak
المصدر: Blood. 133(9)
مصطلحات موضوعية: Immunology, Antineoplastic Agents, Lymphoma, Mantle-Cell, Mice, SCID, medicine.disease_cause, Biochemistry, Small Molecule Libraries, chemistry.chemical_compound, Ikaros Transcription Factor, Mice, Piperidines, In vivo, immune system diseases, Mice, Inbred NOD, hemic and lymphatic diseases, Neoplasms, medicine, Agammaglobulinaemia Tyrosine Kinase, Tumor Cells, Cultured, Bruton's tyrosine kinase, Animals, Humans, Cell Proliferation, Mutation, Lymphoid Neoplasia, biology, Adenine, Cancer, Cell Biology, Hematology, medicine.disease, Xenograft Model Antitumor Assays, Pyrimidines, chemistry, Ibrutinib, Cancer cell, Proteolysis, biology.protein, Cancer research, Pyrazoles, Mantle cell lymphoma, Signal transduction, Signal Transduction
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المؤلفون: Mark Douglas, David T. Weaver, Adam Officer, David M. Weinstock, Yasuhiro Oki, Virginia Kelly, Steven M. Horwitz, Megan Perez, Jacob D. Jaffe, Patrick Kelly, Alison J. Moskowitz, Howard M. Stern, Sara N. Morrow, Francine M. Foss, Kerstin Allen, Patricia L. Myskowski, Pierluigi Porcu, Jon C. Aster, Jennifer Sweeney, Raphael Koch
مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Skin Neoplasms, Maximum Tolerated Dose, Class I Phosphatidylinositol 3-Kinases, T cell, Immunology, Administration, Oral, Neutropenia, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, In vivo, medicine, Class Ib Phosphatidylinositol 3-Kinase, T-cell lymphoma, Humans, Tissue Distribution, Aged, Phosphoinositide-3 Kinase Inhibitors, Aged, 80 and over, Lymphoid Neoplasia, business.industry, Lymphoma, T-Cell, Peripheral, Cell Biology, Hematology, Middle Aged, Prognosis, medicine.disease, Isoquinolines, Duvelisib, Lymphoma, T-Cell, Cutaneous, Lymphoma, 030104 developmental biology, medicine.anatomical_structure, Cell killing, chemistry, Purines, 030220 oncology & carcinogenesis, Hematologic Neoplasms, Cancer research, Female, Safety, business, Idelalisib
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المؤلفون: Hailey Fuchs, Sara N. Morrow, Rafael B Blasco, Alexander J. Brown, Fei-Long Meng, David M. Weinstock, Jacob V. Layer, Richard L. Frock, Elif Karaca, J. Patrick Cleary, Sunhee Kim, Roberto Chiarle, Tovah A. Day, Kristen E. Stevenson, Trevor Tivey, Steven A. Roberts, Alexandria Van Scoyk, Frederick W. Alt
مصطلحات موضوعية: 0301 basic medicine, Rearrangements, DNA End-Joining Repair, Oncogene Proteins, Fusion, Poly ADP ribose polymerase, Poly (ADP-Ribose) Polymerase-1, Chromosomal translocation, PARP3, Nonhomologous end joining, Anaplastic Lymphoma Kinase, Animals, B-Lymphocytes, Fibroblasts, Immunoglobulin Class Switching, Mice, Mouse Embryonic Stem Cells, Poly(ADP-ribose) Polymerases, Receptor Protein-Tyrosine Kinases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, PARP1, Ribose, Fusion, Polymerase, 030304 developmental biology, Oncogene Proteins, 0303 health sciences, Multidisciplinary, biology, Chemistry, Biological Sciences, Embryonic stem cell, Phenotype, Cell biology, Non-homologous end joining, 030104 developmental biology, Immunoglobulin class switching, 030220 oncology & carcinogenesis, biology.protein, DNA
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المؤلفون: Jon C. Aster, Quang-Dé Nguyen, Kay Shigamori, Kristopher A. Sarosiek, Amanda L. Christie, Jeffrey W. Craig, Alexandria Van Scoyk, David M. Weinstock, Christian C. Pallasch, Huiyun Liu, Chen Lossos, Olivia Plana, Kellie E. Kolb, Sara N. Morrow, Alex K. Shalek, Elizabeth A. Morgan, Michael T. Hemann, Rebecca Modiste, Cameron Fraser, Sanjay M. Prakadan, Kristen E. Stevenson
المصدر: SSRN Electronic Journal.
مصطلحات موضوعية: Cyclophosphamide, Chemistry, Phagocytosis, Syk, medicine.disease, Lymphoma, Paracrine signalling, medicine.anatomical_structure, medicine, Cancer research, Unfolded protein response, Alemtuzumab, Bone marrow, medicine.drug
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المؤلفون: Nathanael S. Gray, Sara N. Morrow, Eric T. Wang, Guang Yang, Dennis Dobrovolsky, Eric S. Fischer, Katherine A. Donovan, Zhengnian Li, Tyler B. Faust, Radosław P. Nowak, Steven P. Treon, David M. Weinstock
المصدر: Blood. 132:263-263
مصطلحات موضوعية: biology, Kinase, Bortezomib, Chronic lymphocytic leukemia, Immunology, Cell Biology, Hematology, Protein degradation, medicine.disease, Biochemistry, chemistry.chemical_compound, chemistry, immune system diseases, hemic and lymphatic diseases, Ibrutinib, Cancer research, biology.protein, medicine, Bruton's tyrosine kinase, Mantle cell lymphoma, Tyrosine kinase, medicine.drug
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