المؤلفون: William P. Taylor, Mark Edward Bunnage, Hardwin O'dowd, Michael P. Clark, Dan Crawford, Sanjay Shivayogi Magavi, Bin Song, Jianglin Liang, Timothy J. Senter, Tal Kramer, Juntyma J. Engtrakul, Arun K. Mohanty, Fan Lu, Hong Gao, Yulin Huang, Swett Rebecca Jane, Bryan W. Vought, Ray Winquist, Tony Considine, Ganesh Iyer, Kenneth C. Bonanno, Elisabeth Doyle, Suganthini Nanthakumar, Raymond Kemper, Elaine Krueger, Cameron Stuver Moody, Joyce T. Coll, Paul S. Charifson, John J. Court, Wenxin Gu, Francois Maltais, Gale-Day Zachary, Ananthisrinivas Chakilam, Jon H. Come, John L. Andreassi, Morris Mark A, Brinley Furey, Christina Boucher, Martin Sanders, Harmon J. Zuccola, Gagnon Kevin James, Katrina L. Jackson, Lu Gan, Jonathan A. Phillips

المصدر: Journal of Medicinal Chemistry. 64:17753-17776

مصطلحات موضوعية: endocrine system, endocrine system diseases, Fatty Acid Elongases, Very long chain fatty acid, Central nervous system, Pyrazole, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Enzyme Inhibitors, Adrenoleukodystrophy, Thiazole, chemistry.chemical_classification, Microglia, Substrate (chemistry), medicine.disease, Amides, medicine.anatomical_structure, Enzyme, chemistry, Biochemistry, Pyrazoles, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df83528af04585e5c3ec98c9649f09d
https://doi.org/10.1021/acs.jmedchem.1c00944

المؤلفون: Alberto Stolfi, Sanjay Shivayogi Magavi, Drew Friedmann, Garrett P. Banks, Carlos Lois

مصطلحات موضوعية: Male, Cytoplasm, Neurogenesis, Cell Count, Mice, Transgenic, Neocortex, Biology, Mice, Cell Movement, medicine, Animals, Gliogenesis, General Neuroscience, Pyramidal Cells, Age Factors, Cell Differentiation, Articles, medicine.anatomical_structure, nervous system, Astrocytes, Synaptic plasticity, Neuroglia, Female, Neuron, Neural development, Neuroscience, Astrocyte

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e1c880abc675e2770fa11d681ec1d6
https://resolver.caltech.edu/CaltechAUTHORS:20181002-163832137

المؤلفون: Christian T. Wentz, Sanjay Shivayogi Magavi

مصطلحات موضوعية: medicine.medical_specialty, Cell Survival, Hippocampus, Caspase 3, Hippocampal formation, Biology, Article, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Mice, Internal medicine, Caffeine, medicine, Animals, Cell Proliferation, Pharmacology, Neurons, Environmental enrichment, Dose-Response Relationship, Drug, Stem Cells, Neurogenesis, Cell Differentiation, Antigens, Differentiation, Olfactory bulb, Mice, Inbred C57BL, Dose–response relationship, Endocrinology, chemistry, Central Nervous System Stimulants, Female, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9f2c16f7319e96ce83dd9b3d4d2fe7
https://europepmc.org/articles/PMC2743873/

المؤلفون: Sanjay Shivayogi Magavi

المصدر: Science. 321:1776-1776

مصطلحات موضوعية: Government, Multidisciplinary, Innovator, Law, Schadenfreude, Honeymoon

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad74c1499da0c320f2e1a89634a50fa4
https://doi.org/10.1126/science.321.5897.1776c

المؤلفون: Michael J. Boyd (1764598), Philip N. Collier (1562239), Michael P. Clark (1764619), Hongbo Deng (1764592), Sarathy Kesavan (1950592), Steven M. Ronkin (11798628), Nathan Waal (1720030), Jian Wang (5901), Jingrong Cao (1577356), Pan Li (335711), Jon Come (1562230), Ioana Davies (1764610), John P. Duffy (1764631), John E. Cochran (2160814), John J. Court (1764601), Kishan Chandupatla (2863559), Katrina L. Jackson (2047516), Francois Maltais (2342827), Hardwin O’Dowd (1570984), Christina Boucher (1562233), Tony Considine (11663932), William P. Taylor (1764604), Hong Gao (68166), Ananthisrinivas Chakilam (11663938), Juntyma Engtrakul (11663941), Dan Crawford (8315991), Elizabeth Doyle (11798631), Jonathan Phillips (6332132), Raymond Kemper (11663950), Rebecca Swett (149249), James Empfield (11798634), Mark E. Bunnage (1290480), Paul S. Charifson (1720039), Sanjay Shivayogi Magavi (11798637)

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, throughput radiometric screen, favorable pharmacokinetics culminating, exploring therapeutic approaches, central nervous system, 0 lysophosphatidyl choline, ald patient fibroblasts, 22 , 0 vlcfa synthesis, potent elovl1 inhibitor, selective inhibitor, highly potent, useful tool, type levels, reducing c26, reduced c26, near wild, murine model, may serve, lpc ), ko mice, based compounds, ald )

Relation: https://figshare.com/articles/dataset/Discovery_of_Novel_Orally_Bioavailable_Pyrimidine_Ether-Based_Inhibitors_of_ELOVL1/17131737

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00948.s001