المؤلفون: Do Young Park, Junyeop Lee, Jaeryung Kim, Kangsan Kim, Seonpyo Hong, Sangyeul Han, Yoshiaki Kubota, Hellmut G. Augustin, Lei Ding, Jin Woo Kim, Hail Kim, Yulong He, Ralf H. Adams, Gou Young Koh

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c8b70a95fd88461dbf21669c1f36b7f1

المؤلفون: Shilpa Prabhakar, Xuan Zhang, June Goto, Sangyeul Han, Charles Lai, Roderick Bronson, Miguel Sena-Esteves, Vijaya Ramesh, Anat Stemmer-Rachamimov, David J. Kwiatkowski, Xandra O. Breakefield

المصدر: Neurobiology of Disease, Vol 82, Iss , Pp 22-31 (2015)

مصطلحات موضوعية: Tuberous sclerosis complex, TSC, TSC1, TSC2, Gene therapy, AAV, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996115001758; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/8eae6760b48943a698ff72cfc816c4b9

المؤلفون: Vijaya Ramesh, Anat O. Stemmer-Rachamimov, James F. Gusella, Margaret R. Wallace, Hua Li, Sangyeul Han, Roberta Beauchamp, Elizabeth Stivison, Marianne F. James

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d321c129817ecf5fa554c0db96bee4c
https://doi.org/10.1158/1541-7786.22517862.v1

المؤلفون: James F. Gusella, R. Plotkin, Brendan D. Manning, Anat O, Marianne F. James, Sangyeul Han, Carolyn Polizzano, Anat O. Stemmer-rachamimov, Vijaya Ramesh

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://mcb.asm.org/content/29/15/4250.full.pdf.

مصطلحات موضوعية: org

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.623.2373; http://mcb.asm.org/content/29/15/4250.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.623.2373
http://mcb.asm.org/content/29/15/4250.full.pdf

المؤلفون: Jin Woo Kim, Gou Young Koh, Yulong He, Ralf H. Adams, Lei Ding, Jaeryung Kim, Hellmut G. Augustin, Sangyeul Han, Do Young Park, Yoshiaki Kubota, Hail Kim, Kangsan Kim, Junyeop Lee, Seonpyo Hong

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: 0301 basic medicine, Endothelium, medicine.medical_treatment, Science, Blood–retinal barrier, General Physics and Astronomy, Vascular permeability, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, chemistry.chemical_compound, medicine, Multidisciplinary, biology, Growth factor, Retinal, General Chemistry, Angiopoietin receptor, Cell biology, 030104 developmental biology, medicine.anatomical_structure, chemistry, biology.protein, cardiovascular system, Pericyte, sense organs, Platelet-derived growth factor receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afefba02c49c5d35905c970844cac62
https://doaj.org/article/c8b70a95fd88461dbf21669c1f36b7f1

المؤلفون: Eun Jin Kim, Chansik Yang, Jiyoon Kim, Chungho Kim, Jiyeon Ohk, Sangyeul Han, Ji Yeun Lee, Dongeun Park, Hosung Jung

المصدر: Arteriosclerosis, Thrombosis, and Vascular Biology. 36:1406-1416

مصطلحات موضوعية: 0301 basic medicine, Embryo, Nonmammalian, Genotype, Calmodulin, Angiogenesis, Xenopus, Neovascularization, Physiologic, CHO Cells, Transfection, Receptor tyrosine kinase, Calcium in biology, Dephosphorylation, 03 medical and health sciences, Cricetulus, Human Umbilical Vein Endothelial Cells, Animals, Humans, Protein Interaction Domains and Motifs, Calcium Signaling, Phosphorylation, biology, Gene Expression Regulation, Developmental, Receptor, TIE-2, Embryonic stem cell, Angiopoietin receptor, Cell biology, HEK293 Cells, Phenotype, 030104 developmental biology, Biochemistry, Protein kinase domain, Gene Knockdown Techniques, Mutation, embryonic structures, cardiovascular system, biology.protein, Tyrosine, Cardiology and Cardiovascular Medicine, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17130f70d4ff3471605eb85549a50726
https://doi.org/10.1161/atvbaha.116.307619

المؤلفون: Yoonha Hwang, Jeongwoon Choi, Tae Young Chung, Jee Myung Yang, Gou Young Koh, Pilhan Kim, YongJoo Kim, Wang-Yuhl Oh, WooJhon Choi, Hosung Bae, Jang Ryul Park, Intae Park, Jaeryung Kim, Yoshiaki Kubota, Sangyeul Han, Hellmut G. Augustin

المصدر: Science Advances

مصطلحات موضوعية: Vascular Endothelial Growth Factor A, genetic structures, Angiogenesis, Fluorescent Antibody Technique, Animals, Genetically Modified, chemistry.chemical_compound, Macular Degeneration, Mice, 0302 clinical medicine, Hypoxia, Research Articles, 0303 health sciences, Multidisciplinary, biology, Age Factors, SciAdv r-articles, Angiopoietin receptor, Receptor, TIE-2, Vascular endothelial growth factor, Choroidal neovascularization, surgical procedures, operative, embryonic structures, cardiovascular system, Disease Susceptibility, medicine.symptom, tissues, Research Article, Protein Binding, Signal Transduction, Transcriptional Activation, medicine.medical_specialty, Vision Disorders, Models, Biological, 03 medical and health sciences, Ophthalmology, medicine, Angiopoietin-1, Animals, Regeneration, 030304 developmental biology, business.industry, Regeneration (biology), Gene Expression Profiling, Macular degeneration, Hypoxia (medical), medicine.disease, eye diseases, Choroidal Neovascularization, Blockade, Disease Models, Animal, chemistry, Gene Expression Regulation, 030221 ophthalmology & optometry, biology.protein, sense organs, business, Gene Deletion, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2427894bd690ab090a9df91c0ec903b1
http://europepmc.org/articles/PMC6374104

المؤلفون: Injune Kim, Il Kug Kim, Intae Park, Jeong Hoon Kim, Jeomil Bae, Doheon Lee, Sangyeul Han, Seung Ja Oh, Chan Kim, Gou Young Koh, Hellmut G. Augustin, Seungjoo Lee, Dong Cheol Woo, Yulong He, Jin-Sung Park

المصدر: Cancer cell. 31(1)

مصطلحات موضوعية: Normalization (statistics), 0301 basic medicine, Cancer Research, Angiogenesis, Cell, Antineoplastic Agents, Breast Neoplasms, Antibodies, Metastasis, 03 medical and health sciences, Carcinoma, Lewis Lung, Mice, 0302 clinical medicine, Immune system, Glioma, medicine, Temozolomide, Tumor Microenvironment, Animals, Humans, Tumor microenvironment, biology, business.industry, Lewis lung carcinoma, Drug Synergism, Cell Biology, Ribonuclease, Pancreatic, medicine.disease, Angiopoietin receptor, Receptor, TIE-2, Dacarbazine, 030104 developmental biology, medicine.anatomical_structure, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Immunology, Drug delivery, biology.protein, Cancer research, Female, business, Neoplasm Transplantation, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b9600c1124f2a84904fa0885374959
https://pubmed.ncbi.nlm.nih.gov/27960088

المؤلفون: Vijaya Ramesh, Brendan D. Manning, Carolyn Polizzano, Anat Stemmer-Rachamimov, James F. Gusella, Sangyeul Han, Marianne James, Scott R. Plotkin

المصدر: Molecular and Cellular Biology. 29:4250-4261

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Immunoblotting, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biology, Transfection, Cell Line, Mice, Phosphatidylinositol 3-Kinases, Tumor Cells, Cultured, otorhinolaryngologic diseases, Animals, Humans, RNA, Small Interfering, Protein kinase A, Molecular Biology, Transcription factor, Cells, Cultured, Cell Proliferation, Mice, Knockout, Sirolimus, Neurofibromin 2, Antibiotics, Antineoplastic, Cell growth, TOR Serine-Threonine Kinases, Cell Cycle, Proteins, Articles, Cell Biology, Fibroblasts, Cell cycle, Flow Cytometry, Molecular biology, Merlin (protein), Multiprotein Complexes, Cancer research, Arachnoid, TSC2, Signal transduction, Meningioma, Proto-Oncogene Proteins c-akt, Neurilemmoma, Signal Transduction, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8092203f467a0a50014a6e1ad1812a7a
https://doi.org/10.1128/mcb.01581-08

المؤلفون: Vijaya Ramesh, Sangyeul Han, Andrew E. Rosenberg, Carolyn Polizzano, Gunnlaugur P. Nielsen, Francis J. Hornicek

المصدر: Clinical Cancer Research. 15:1940-1946

مصطلحات موضوعية: musculoskeletal diseases, Cancer Research, mTORC1, Mechanistic Target of Rapamycin Complex 1, Article, Tuberous sclerosis, Tuberous Sclerosis Complex 2 Protein, Chordoma, medicine, Humans, Tensin, PTEN, Protein kinase B, Cell Proliferation, Sirolimus, biology, Cell growth, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, PTEN Phosphohydrolase, Proteins, medicine.disease, Oncology, Multiprotein Complexes, Cancer research, biology.protein, biological phenomena, cell phenomena, and immunity, Signal transduction, Proto-Oncogene Proteins c-akt, Sacral Chordoma, Signal Transduction, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c63c677f5df92db6109388db524083
https://doi.org/10.1158/1078-0432.ccr-08-2364

المؤلفون: Sangyeul Han, Yu Zhou, Dan Ehninger, Vijaya Ramesh, Carrie Shilyansky, David J. Kwiatkowski, Alcino J. Silva, Weidong Li

المصدر: Nature Medicine. 14:843-848

مصطلحات موضوعية: Male, Heterozygote, Hippocampus, Neuropathology, Article, General Biochemistry, Genetics and Molecular Biology, Mice, Tuberous sclerosis, Epilepsy, Tuberous Sclerosis, Tuberous Sclerosis Complex 2 Protein, medicine, Animals, Learning, Sirolimus, Behavior, Animal, business.industry, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, General Medicine, medicine.disease, Mice, Inbred C57BL, Transplantation, medicine.anatomical_structure, Immunology, Female, TSC1, TSC2, Cognition Disorders, business, Protein Kinases, Neuroscience, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe66db7f1dc1749bcf9731d72d2a4725
https://doi.org/10.1038/nm1788

المؤلفون: Vijaya Ramesh, Rochelle M. Witt, Carolyn Polizzano, Sangyeul Han, Túlio M. Santos, Bernardo L. Sabatini

المصدر: Cellular Signalling. 20:1084-1091

مصطلحات موضوعية: Ubiquitin-Protein Ligases, Molecular Sequence Data, Mutation, Missense, Ubiquitin-conjugating enzyme, Article, Mixed Function Oxygenases, Ubiquitin, Tuberous Sclerosis, Tuberous Sclerosis Complex 2 Protein, parasitic diseases, Animals, Humans, Amino Acid Sequence, Phosphorylation, Protein kinase B, Cells, Cultured, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, Neurons, biology, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, Ubiquitination, Cell Biology, Protein Structure, Tertiary, Rats, Ubiquitin ligase, RING finger domain, Ubiquitin-Conjugating Enzymes, embryonic structures, biology.protein, Cancer research, TSC2, Protein Kinases, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca4b3822c3b9f5d1d406423e7b69d47
https://doi.org/10.1016/j.cellsig.2008.01.020

المؤلفون: Su Jin Kim, Seungjoo Lee, Seung Ja Oh, Kwang Hoon Lee, Gou Young Koh, Injune Kim, Eun Young Ko, Hyung Chan Kim, Su Young Chae, Junhao Hu, Chungho Kim, Nuri Oh, Kyung Eun Kim, David Kim, Hellmut G. Augustin, Yoon Sook Lee, Inwon Park, Dae Hyun Lee, Pilhan Kim, Yoshikazu Nakaoka, Jung Hoon Lee, Seung Jun Lee, Seokkyun Kim, Yong In Kim, Sung Hyun Kim, Hyo Seon Lee, Paul H. Song, Yulong He, Sangyeul Han

المصدر: Science translational medicine. 8(335)

مصطلحات موضوعية: 0301 basic medicine, Endothelium, Angiogenesis, medicine.medical_treatment, Vesicular Transport Proteins, Neovascularization, Physiologic, Antibodies, Sepsis, Angiopoietin-2, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Human Umbilical Vein Endothelial Cells, Animals, Humans, Receptor, biology, Septic shock, General Medicine, Ribonuclease, Pancreatic, medicine.disease, Angiopoietin receptor, Receptor, TIE-2, Mice, Inbred C57BL, 030104 developmental biology, Cytokine, medicine.anatomical_structure, Neutrophil Infiltration, 030220 oncology & carcinogenesis, Immunology, biology.protein, Endothelium, Vascular, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247cb6ef10af3af2dd6211a4559d1676
https://pubmed.ncbi.nlm.nih.gov/27099172

المؤلفون: Seung Ja Oh, Sangyeul Han, Hyo Seon Lee, Paul H. Song, Eun Young Ko, Hyung Chan Kim, Chungho Kim, Kwang Hoon Lee, Seokkyun Kim, Kyung Eun Kim, Yoon Sook Lee, Yong In Kim

المصدر: The Journal of biological chemistry. 289(45)

مصطلحات موضوعية: Integrins, Angiogenesis, Glutamine, Integrin, CHO Cells, Biochemistry, CD49c, Collagen receptor, Focal adhesion, Angiopoietin-2, Cricetulus, Cell Movement, Cell Line, Tumor, Cricetinae, Neoplasms, Cell Adhesion, Animals, Humans, Neoplasm Invasiveness, Neoplasm Metastasis, Molecular Biology, biology, integumentary system, Neovascularization, Pathologic, Chemistry, Endothelial Cells, Cell Biology, Receptor, TIE-2, Cell biology, Protein Structure, Tertiary, Endothelial stem cell, Integrin alpha M, Gene Expression Regulation, embryonic structures, biology.protein, cardiovascular system, Integrin, beta 6, sense organs, tissues, hormones, hormone substitutes, and hormone antagonists, Integrin alpha5beta1, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aca435ab6ef8f7ea9ce5ea83ff481fc
https://pubmed.ncbi.nlm.nih.gov/25237190

المؤلفون: Sangyeul Han, Lin Li, Pradeep G. Bhide, Marianne James, Aaron DiAntonio, Vijaya Ramesh, Roberta L. Beauchamp, Clara F. Burande, Samira Bahl, Nicole A. Smith, Sun Kim

المصدر: The Journal of biological chemistry. 287(36)

مصطلحات موضوعية: Cell signaling, Ubiquitin-Protein Ligases, Nerve Tissue Proteins, mTORC1, Mechanistic Target of Rapamycin Complex 1, Biochemistry, Corpus Callosum, Mice, Ubiquitin, stomatognathic system, parasitic diseases, Tuberous Sclerosis Complex 2 Protein, Animals, Humans, Caenorhabditis elegans, Molecular Biology, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, reproductive and urinary physiology, biology, F-Box Proteins, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, Ubiquitination, Proteins, Cell Biology, Molecular biology, Axons, Mice, Mutant Strains, Ubiquitin ligase, Cell biology, Protein Structure, Tertiary, HEK293 Cells, nervous system, Ubiquitin ligase complex, Multiprotein Complexes, embryonic structures, Synapses, biology.protein, Drosophila, Signal transduction, Carrier Proteins, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b73904cb8ad8d92c83511e417a2cfe
https://pubmed.ncbi.nlm.nih.gov/22798074

المؤلفون: Mark Bowser, Vanishree Murthy, Pradeep G. Bhide, Túlio M. Santos, Vijaya Ramesh, Karen Sazani, Sangyeul Han, Roberta L. Beauchamp

المصدر: Journal of neuroscience research. 83(2)

مصطلحات موضوعية: Gene isoform, Transcriptional Activation, Blotting, Western, Molecular Sequence Data, Gene Expression, Biology, Kidney, Mixed Function Oxygenases, Proto-Oncogene Proteins c-myc, Cellular and Molecular Neuroscience, Exon, Mice, Multienzyme Complexes, Animals, Humans, Protein Isoforms, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, Peptide sequence, Gene, Lung, Reverse Transcriptase Polymerase Chain Reaction, Alternative splicing, RNA, Kidney metabolism, Brain, Exons, Blotting, Northern, Molecular biology, Immunohistochemistry, Rats, Alternative Splicing, RNA splicing, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7744175ebef2e23b4b3928ee217ba0
https://pubmed.ncbi.nlm.nih.gov/16342205

المؤلفون: Túlio M. Santos, Elizabeth A. Thiele, Ana Cristina Scheidt Puga, Sangyeul Han, Vijaya Ramesh, Mia McCollin, Jenn Roy, Anat Stemmer-Rachamimov

المصدر: Cancer research. 64(3)

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Cancer Research, Pathology, medicine.medical_specialty, Tumor suppressor gene, MAP Kinase Kinase 2, MAP Kinase Kinase 1, Biology, Astrocytoma, Protein Serine-Threonine Kinases, Tuberous Sclerosis Complex 1 Protein, Tuberous sclerosis, Tuberous Sclerosis, Proto-Oncogene Proteins, Tuberous Sclerosis Complex 2 Protein, medicine, Humans, Phosphorylation, Protein kinase B, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase Kinases, Mitogen-Activated Protein Kinase 3, Brain Neoplasms, Ribosomal Protein S6 Kinases, TOR Serine-Threonine Kinases, Tumor Suppressor Proteins, Proteins, Human brain, Protein-Tyrosine Kinases, medicine.disease, Phosphoproteins, Tuberous sclerosis protein, Enzyme Activation, Repressor Proteins, medicine.anatomical_structure, Oncology, Protein Biosynthesis, TSC1, TSC2, Mitogen-Activated Protein Kinases, Protein Kinases, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc15f301f622b8a4e9aace2bcec08f23
https://pubmed.ncbi.nlm.nih.gov/14871804

المؤلفون: Roberta L. Beauchamp, Naoto Ito, Vijaya Ramesh, Sangyeul Han, Luciana A. Haddad, Nicole A. Smith, Vanishree Murthy

المصدر: The Journal of biological chemistry. 279(2)

مصطلحات موضوعية: Central Nervous System, Amino Acid Motifs, Biochemistry, PC12 Cells, Tuberous Sclerosis Complex 1 Protein, Mixed Function Oxygenases, Tuberous sclerosis, Ubiquitin, Drosophila Proteins, Caenorhabditis elegans, Conserved Sequence, Glutathione Transferase, Zinc finger, Genetics, Neurons, TSC1-TSC2 complex, biology, Brain, Zinc Fingers, Immunohistochemistry, Ubiquitin ligase, Cell biology, medicine.anatomical_structure, Phenotype, Drosophila, Protein Binding, congenital, hereditary, and neonatal diseases and abnormalities, DNA, Complementary, Genotype, Recombinant Fusion Proteins, Ubiquitin-Protein Ligases, Nerve Tissue Proteins, Transfection, Models, Biological, Cell Line, Proto-Oncogene Proteins c-myc, parasitic diseases, Tuberous Sclerosis Complex 2 Protein, medicine, Animals, Humans, Molecular Biology, Adaptor Proteins, Signal Transducing, Models, Genetic, Tumor Suppressor Proteins, Proteins, Cell Biology, biology.organism_classification, medicine.disease, Precipitin Tests, Protein Structure, Tertiary, Rats, Repressor Proteins, Mutation, biology.protein, TSC1, TSC2, Carrier Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::790333740c1fb8b598d83988e7829b84
https://pubmed.ncbi.nlm.nih.gov/14559897

المؤلفون: Chansik Yang, Jiyeon Ohk, Ji Yeun Lee, Eun Jin Kim, Jiyoon Kim, Sangyeul Han, Dongeun Park, Hosung Jung, Chungho Kim

المصدر: Arteriosclerosis, Thrombosis & Vascular Biology; Jul2016, Vol. 36 Issue 7, p1406-1416, 11p

المؤلفون: Sangyeul Han, Seung-Jun Lee, Kyung Eun Kim, Hyo Seon Lee, Nuri Oh, Inwon Park, Eun Ko, Seung Ja Oh, Yoon-Sook Lee, Kim, David, Seungjoo Lee, Dae Hyun Lee, Kwang-Hoon Lee, Su Young Chae, Jung-Hoon Lee, Su-Jin Kim, Hyung-Chan Kim, Seokkyun Kim, Sung Hyun Kim, Chungho Kim

المصدر: Science Translational Medicine; 4/20/2016, Vol. 8 Issue 335, p1-11, 11p, 7 Graphs

مصطلحات موضوعية: VASCULAR endothelial growth factors, SEPTICEMIA treatment, ANGIOPOIETIN-2, GLYCOCALYX, DISEASE progression