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المؤلفون: Aili L. Lazaar, Jonathan Robertson, Sandra J. Baldwin, Ruth J. Mayer, Navin Goyal, Lucy Yang, Ruth Tal-Singer, Rebecca L. Boardley, Ian B. Wilkinson, Joseph Cheriyan, David E. Newby
المصدر: British Journal of Clinical Pharmacology. 81:971-979
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Epoxide hydrolase 2, business.industry, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Pharmacokinetics, Research centre, Pharmacodynamics, Healthy volunteers, Medicine, Pharmacology (medical), business, Adverse effect, 030217 neurology & neurosurgery
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المؤلفون: Sandra J. Baldwin, Jianfeng Xu, Matt Davies, Jerry Jeffrey, Matthew Burke, Allan R Tenorio, Brian A. Johns, Elizabeth Gould, Amanda Peppercorn, Roxanne C. Jewell, Mark Johnson, Yu Lou
المصدر: Pharmacology researchperspectives. 6(4)
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Anti-HIV Agents, Cmax, Biological Availability, Pharmacology, Placebo, 030226 pharmacology & pharmacy, Chrysenes, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, medicine, Humans, Drug Interactions, General Pharmacology, Toxicology and Pharmaceutics, Adverse effect, Ritonavir, business.industry, Middle Aged, Healthy Volunteers, Bioavailability, Regimen, Butyrates, 030104 developmental biology, Neurology, Tolerability, Area Under Curve, Female, business, Pentacyclic Triterpenes, medicine.drug, Half-Life
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المؤلفون: Charlotte A. Ashby, Stephen E. Clarke, Andrew Ayrton, Sandra J. Baldwin, Lin Yue, Jo L. Bramhall, Steven R. Hood, Paul R. Murdock
المصدر: Drug Metabolism and Disposition. 34:1063-1069
مصطلحات موضوعية: Male, Drug Evaluation, Preclinical, Pharmaceutical Science, Catalysis, Dexamethasone, Rats, Sprague-Dawley, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, beta-Naphthoflavone, In vivo, Cytochrome P-450 CYP1A1, TaqMan, Animals, Cytochrome P-450 CYP3A, Taq Polymerase, RNA, Messenger, Pharmacology, Messenger RNA, biology, Reverse Transcriptase Polymerase Chain Reaction, Clofibric acid, Reproducibility of Results, Cytochrome P450, Molecular biology, Reverse transcriptase, Rats, Reverse transcription polymerase chain reaction, Liver, chemistry, Enzyme Induction, Phenobarbital, Cytochrome P-450 CYP2B1, biology.protein, Aryl Hydrocarbon Hydroxylases, Ex vivo
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المؤلفون: Kevin M. Thewlis, Sandra J. Baldwin, C. E. Shardlow, P. J. Kelly, P. Jeffrey, Nigel Deeks, Leanne Cutler, Andrew Ayrton, Geoffrey Stemp, Nigel E. Austin, M. Nash
المصدر: Xenobiotica. 31:677-686
مصطلحات موضوعية: Male, medicine.medical_specialty, Health, Toxicology and Mutagenesis, Biological Availability, In Vitro Techniques, Pharmacology, Toxicology, Biochemistry, Dogs, Species Specificity, Pharmacokinetics, In vivo, Dopamine receptor D3, Tetrahydroisoquinolines, Internal medicine, Nitriles, medicine, Animals, Humans, Aldehyde oxidase, biology, Fissipedia, Receptors, Dopamine D3, Antagonist, General Medicine, Metabolism, biology.organism_classification, Aldehyde Oxidoreductases, In vitro, Rats, Aldehyde Oxidase, Dopamine D2 Receptor Antagonists, Macaca fascicularis, Endocrinology, Liver, Microsomes, Liver, Quinolines, Dopamine Antagonists, Female, NADP
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المؤلفون: Jackie C. Bloomer, Sandra J. Baldwin, S E Clarke, R J Chenery, G J Smith, Andrew Ayrton
المصدر: British Journal of Clinical Pharmacology. 38:557-566
مصطلحات موضوعية: Indoles, CYP2B6, CYP3A, Metabolite, Tropisetron, In Vitro Techniques, Pharmacology, Hydroxylation, Granisetron, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, medicine, Cytochrome P-450 Enzyme Inhibitors, Humans, Pharmacology (medical), CYP2A6, biology, Chemistry, CYP1A2, Cytochrome P450, Ondansetron, Isoenzymes, Kinetics, Microsomes, Liver, biology.protein, Serotonin Antagonists, Research Article, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd51d46c7ed1ac7e3bba5da19ec371c
https://doi.org/10.1111/j .1365-2125.1994.tb04397.x -
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المؤلفون: Andrew Ayrton, R J Chenery, G J Smith, Sandra J. Baldwin, S E Clarke, Jackie C. Bloomer
المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 25(3)
مصطلحات موضوعية: Male, Furafylline, Health, Toxicology and Mutagenesis, Tolbutamide, Pharmacology, Toxicology, Biochemistry, Mixed Function Oxygenases, chemistry.chemical_compound, Sulfaphenazole, medicine, Cytochrome P-450 Enzyme Inhibitors, Humans, IC50, biology, Chemistry, Cytochrome P450, Cytochrome P-450 CYP2E1, General Medicine, Ketoconazole, Enzyme inhibitor, Steroid Hydroxylases, Microsome, biology.protein, Microsomes, Liver, Female, Aryl Hydrocarbon Hydroxylases, medicine.drug
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المؤلفون: Jacqueline C. Bloomer, Randall S. Sozio, Sandra J. Baldwin, Andrew Ayrton, Stephen E. Clarke, Richard J. Chenery
المصدر: Chemical research in toxicology. 7(6)
مصطلحات موضوعية: Male, Furafylline, Toxicology, Hydroxylation, Mixed Function Oxygenases, Substrate Specificity, Rats, Sprague-Dawley, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, medicine, Animals, Humans, Enzyme kinetics, biology, Chemistry, Substrate (chemistry), Cytochrome P450, Lauric Acids, Cytochrome P-450 CYP2E1, Oxidoreductases, N-Demethylating, General Medicine, Lauric acid, Rats, Kinetics, Ketoconazole, Biochemistry, Chlorzoxazone, biology.protein, Microsome, Microsomes, Liver, Female, Cytochrome P-450 CYP4A, medicine.drug