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1The impact of sialylation linkage‐type on the pharmacokinetics of recombinant butyrylcholinesterases
المؤلفون: Younji Seo, Sandra Chough, Shuang Yang, Joseph P. Balthasar, Cheng-Yu Chung, Michael J. Betenbaugh, John F. Cipollo, Qiong Wang
المصدر: Biotechnology and Bioengineering. 117:157-166
مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Glycan, Sialyltransferase, Bioengineering, CHO Cells, 01 natural sciences, Applied Microbiology and Biotechnology, Mice, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, In vivo, Cricetinae, 010608 biotechnology, Animals, Humans, Butyrylcholinesterase, chemistry.chemical_classification, biology, Chemistry, Chinese hamster ovary cell, N-Acetylneuraminic Acid, Recombinant Proteins, Sialic acid, carbohydrates (lipids), 030104 developmental biology, Biochemistry, Protein sialylation, biology.protein, Glycoprotein, Biotechnology
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2Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production
المؤلفون: Weiming Yang, Sandra Chough, Rahul Bhattacharya, Michael J. Betenbaugh, Qiong Wang, Yingwei Hu, Christopher T. Saeui, Cheng-Yu Chung, Kevin J. Yarema, Ganglong Yang, Bojiao Yin, Yiqun Chen, Hui Zhang
المصدر: Biotechnology journal. 14(4)
مصطلحات موضوعية: 0106 biological sciences, Glycan, Glycosylation, Butyrate, CHO Cells, Protein Engineering, 01 natural sciences, Applied Microbiology and Biotechnology, law.invention, chemistry.chemical_compound, Cricetulus, law, Polysaccharides, Tandem Mass Spectrometry, 010608 biotechnology, Cricetinae, Protein biosynthesis, Animals, Humans, Erythropoietin, chemistry.chemical_classification, biology, Chinese hamster ovary cell, 010401 analytical chemistry, Sodium butyrate, Hexosamines, General Medicine, Recombinant Proteins, 0104 chemical sciences, carbohydrates (lipids), Enzyme, chemistry, Biochemistry, Recombinant DNA, biology.protein, Molecular Medicine, Butyric Acid, Chromatography, Liquid