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المؤلفون: Hannah J. Gleneadie, Alfredo A. Molinolo, Deena M.A. Gendoo, Yao Jiang, Amy H. Baker, Jennifer L. Bryant, Sally Roberts, Paloma Garcia, Megan Burley, Joanna L Parish, J. Silvio Gutkind, Hisham Mehanna, Ben A. Scheven, Malgorzata Wiench, Nikolaos Batis, Farhat L. Khanim, Paul R. Cooper, Samuel J.H. Clokie
المصدر: Cancer Letters
مصطلحات موضوعية: Male, 0301 basic medicine, Cancer Research, Epigenetic therapies, AA, arachidonic acid, HNSCC, head and neck squamous cell carcinoma, medicine.disease_cause, Mice, chemistry.chemical_compound, 0302 clinical medicine, DRI, dose reduction index, Superoxides, GSH, glutathione, NAPQI, N-acetyl p-benzquinone-imine, TXNRD, thioredoxin reductase, LOX, lipoxygenase, PTGS2, prostaglandin-endoperoxidase synthase 2, ERV, endogenous retrovirus, Cell Differentiation, Drug Synergism, Oncology, Head and Neck Neoplasms, Leukemia, Myeloid, 030220 oncology & carcinogenesis, Deoxycytidine, AML, acute myeloid leukaemia, medicine.drug, COX-2, cyclooxygenase 2, Antimetabolites, Antineoplastic, DNA damage, Decitabine, HL-60 Cells, Article, Acute myeloid leukaemia, 03 medical and health sciences, ROS, reactive oxygen species, Cell Line, Tumor, PGE2, prostaglandin E2, medicine, Animals, Humans, DAC, 5-aza-2′-deoxycytidine, Acetaminophen, Cell Proliferation, CMAP, Connectivity Map, Squamous Cell Carcinoma of Head and Neck, business.industry, CI, combination index, Head and neck squamous cell carcinoma, medicine.disease, Xenograft Model Antitumor Assays, Head and neck squamous-cell carcinoma, Demethylating agent, Oxidative Stress, 030104 developmental biology, chemistry, Cancer cell, Cancer research, NAC, N-acetyl-cysteine, TXN, thioredoxin, Reactive Oxygen Species, business, Oxidative stress
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المؤلفون: Deena M.A. Gendoo, Samuel J.H. Clokie, Alfredo A. Molinolo, Ben A. Scheven, Malgorzata Wiench, Nikolaos Batis, Farhat L. Khanim, Jennifer L. Bryant, Paloma Garcia, Yao Jiang, Amy H. Baker, Hannah J. Gleneadie, Paul R. Cooper, Sally Roberts, Hisham Mehanna, J. Silvio Gutkind
مصطلحات موضوعية: 0303 health sciences, business.industry, DNA damage, Decitabine, Glutathione, medicine.disease, medicine.disease_cause, Head and neck squamous-cell carcinoma, 3. Good health, Demethylating agent, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Cancer cell, medicine, Cancer research, Thioredoxin, business, Oxidative stress, 030304 developmental biology, medicine.drug
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المؤلفون: Alaa Afif Mohammed, Yong-hui Jiang, Thalia Antoniadi, Cynthia J. Curry, Celia Zazo Seco, Dorine Bax, Slavé Petrovski, Samuel J.H. Clokie, Vandana Shashi, Stephen W. Wilson, Dianne Gerrelli, Nicola K. Ragge, Marco Tartaglia, Nicolas Chassaing, Andrea Ciolfi, Marleen Simon, Bruce D. Gelb, Helle Andersen, Zöe Powis, Patrick Calvas, Jennifer A. Sullivan, Fabiola Ceroni, Constance Smith-Hicks, Emanuele Bellacchio, Kristina Pilekær Sørensen, Rodrigo M. Young, Christina Fagerberg, Alessandro De Luca, Ellen van Binsbergen, Luigi Memo, William B. Dobyns, Anna Chassevent, Berta Crespo, Richard J. Holt
المساهمون: Holt R.J., Young R.M., Crespo B., Ceroni F., Curry C.J., Bellacchio E., Bax D.A., Ciolfi A., Simon M., Fagerberg C.R., van Binsbergen E., De Luca A., Memo L., Dobyns W.B., Mohammed A.A., Clokie S.J.H., Zazo Seco C., Jiang Y.-H., Sorensen K.P., Andersen H., Sullivan J., Powis Z., Chassevent A., Smith-Hicks C., Petrovski S., Antoniadi T., Shashi V., Gelb B.D., Wilson S.W., Gerrelli D., Tartaglia M., Chassaing N., Calvas P., Ragge N.K.
المصدر: Holt, R J, Young, R M, Crespo, B, Ceroni, F, Curry, C J, Bellacchio, E, Bax, D A, Ciolfi, A, Simon, M, Fagerberg, C R, van Binsbergen, E, De Luca, A, Memo, L, Dobyns, W B, Mohammed, A A, Clokie, S J H, Zazo Seco, C, Jiang, Y H, Sørensen, K P, Andersen, H, Sullivan, J, Powis, Z, Chassevent, A, Smith-Hicks, C, Petrovski, S, Antoniadi, T, Shashi, V, Gelb, B D, Wilson, S W, Gerrelli, D, Tartaglia, M, Chassaing, N, Calvas, P & Ragge, N K 2019, ' De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies ', American Journal of Human Genetics, vol. 105, no. 3, pp. 640-657 . https://doi.org/10.1016/j.ajhg.2019.07.005
American Journal of Human Geneticsمصطلحات موضوعية: Adult, Male, Adolescent, hedgehog, Ubiquitin-Protein Ligases, brain, Mutation, Missense, Biology, Fingers, 03 medical and health sciences, Wnt, FBXW11, Report, Genetics, medicine, Humans, Noonan syndrome, Eye Abnormalities, Child, Exome, Zebrafish, development, Genetics (clinical), 030304 developmental biology, 0303 health sciences, neurodevelopment, digit, 030305 genetics & heredity, Wnt signaling pathway, WD40, medicine.disease, biology.organism_classification, beta-Transducin Repeat-Containing Proteins, Phenotype, eye, human development, Ubiquitin ligase complex, Child, Preschool, Eye development, Female
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