المؤلفون: Jeff Henise, Shaun D. Fontaine, Brian R. Hearn, Samuel J. Pfaff, Eric L. Schneider, Julia Malato, Donghui Wang, Byron Hann, Gary W. Ashley, Daniel V. Santi

المصدر: International Journal of Polymer Science, Vol 2019 (2019)

مصطلحات موضوعية: Chemical technology, TP1-1185

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1687-9422; https://doaj.org/toc/1687-9430

URL الوصول: https://doaj.org/article/4d40cbe04a32493b86028345287c8f5e

المؤلفون: Ari J. Green, Victoria A. Rafalski, Reuben Thomas, Michael A. Pleiss, Mark A. Petersen, Kim M. Baeten, Andrew S. Mendiola, Zhaoqi Yan, Katerina Akassoglou, Michelle R. Arkin, Alexander R. Pico, Jae K. Ryu, Catherine Bedard, Samuel J. Pfaff, Sophia Bardehle, Xiqian Jiang, Sean Thomas, Anke Meyer-Franke, Alexander Williams, Kenny K. H. Ang, Michael R. Machado, Benoit G. Bruneau, Pamela E. Rios Coronado, Reshmi Tognatta, Rosa Meza-Acevedo, Kristina Hanspers, Mario Merlini, Jin Wang, Christopher W. Wilson, Scott S. Zamvil

المصدر: Nature immunology, vol 21, iss 5
Nature immunology

مصطلحات موضوعية: 0301 basic medicine, Neurodegenerative, medicine.disease_cause, Inbred C57BL, Antioxidants, Transcriptome, Mice, 0302 clinical medicine, Immunology and Allergy, Innate, 2.1 Biological and endogenous factors, Gene Regulatory Networks, Aetiology, Encephalomyelitis, Microglia, Neurodegeneration, Cell biology, Mutant Strains, medicine.anatomical_structure, 5.1 Pharmaceuticals, Neurological, Female, Neurogenic Inflammation, Single-Cell Analysis, Development of treatments and therapeutic interventions, Sequence Analysis, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Immunology, Biology, Neuroprotection, Article, 03 medical and health sciences, Experimental, Immunity, medicine, Genetics, Animals, Humans, Neuroinflammation, Innate immune system, Sequence Analysis, RNA, Animal, Gene Expression Profiling, Neurosciences, Isoxazoles, medicine.disease, Immunity, Innate, Mice, Mutant Strains, High-Throughput Screening Assays, Mice, Inbred C57BL, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Disease Models, bacteria, RNA, Oxidative stress, 030215 immunology, Autoimmune

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9c0b9c6b131eb0b5b3e3e9245daea5
https://escholarship.org/uc/item/9x52r3t1

المؤلفون: Eugene Hur, Samuel J Pfaff, E Sturgis Payne, Hanne Grøn, Benjamin M Buehrer, Robert J Fletterick

المصدر: PLoS Biology, Vol 2, Iss 9, p E274 (2004)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC509409?pdf=render; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

URL الوصول: https://doaj.org/article/875204b5433f4de2a99163ae7bb3892b

المؤلفون: Eugene Hur, Samuel J. Pfaff, E. Sturgis Payne, Hanne Grøn, Benjamin M. Buehrer, Robert J. Fletterick

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/60/0c/PLoS_Biol_2004_Sep_24_2(9)_e274.tar.gz

وصف الملف: application/zip

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.691

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.285.691

المؤلفون: Eric L. Schneider, David G. Parkes, Samuel J. Pfaff, Brian R. Hearn, Daniel V. Santi, Niels Vrang, Gary W. Ashley, Ralph Reid

المصدر: ACS Chemical Biology. 12:2107-2116

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.medical_specialty, Time Factors, medicine.drug_class, 030209 endocrinology & metabolism, Pharmacology, Biochemistry, Glucagon-Like Peptide-1 Receptor, Hydrogel, Polyethylene Glycol Dimethacrylate, 03 medical and health sciences, Subcutaneous injection, Drug Delivery Systems, 0302 clinical medicine, Pharmacokinetics, In vivo, Internal medicine, medicine, Humans, Hypoglycemic Agents, Glucagon-like peptide 1 receptor, Molecular Structure, Chemistry, General Medicine, Microspheres, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Pharmacodynamics, Drug delivery, Molecular Medicine, Exenatide, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03110b01d8317302125ea55db88b0566
https://doi.org/10.1021/acschembio.7b00218

المؤلفون: Sophia Bardehle, Benoit G. Bruneau, Michelle R. Arkin, Pamela E. Rios Coronado, Xiqian Jiang, Sean Thomas, Zhaoqi Yan, Reuben Thomas, Kenny K. H. Ang, Mark A. Petersen, Catherine Bedard, Kristina Hanspers, Reshmi Tognatta, Anke Meyer-Franke, Mario Merlini, Andrew S. Mendiola, Alexander R. Pico, Alexander Williams, Ari J. Green, Samuel J. Pfaff, Victoria A. Rafalski, Rosa Meza-Acevedo, Jin Wang, Kim M. Baeten, Michael A. Pleiss, Michael R. Machado, Katerina Akassoglou, Jae K. Ryu, Christopher W. Wilson, Scott S. Zamvil

المصدر: Nature Immunology. 21:1135-1135

مصطلحات موضوعية: business.industry, Immunology, Cancer research, Immunology and Allergy, Medicine, Profiling (information science), business, Therapeutic targeting, medicine.disease_cause, Neuroinflammation, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d9ef6cde0bf1b320d23e818ad32ad849
https://doi.org/10.1038/s41590-020-0754-x

المؤلفون: Daniel V. Santi, Shaun D. Fontaine, Jeff Henise, Brian R. Hearn, Eric L. Schneider, Gary W. Ashley, Samuel J. Pfaff

المصدر: Journal of controlled release : official journal of the Controlled Release Society. 278

مصطلحات موضوعية: 0301 basic medicine, Polymers, Pharmaceutical Science, Octreotide, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Drug Delivery Systems, In vivo, Kinetic isotope effect, Animals, Drug Carriers, Chemistry, technology, industry, and agriculture, Hydrogels, Biodegradation, Deuterium, Controlled release, Combinatorial chemistry, Rats, Drug Liberation, 030104 developmental biology, Cross-Linking Reagents, Covalent bond, Drug delivery, Self-healing hydrogels, Linker, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645898609bf6b51c6d2025b4380caa39
https://pubmed.ncbi.nlm.nih.gov/29577950

المؤلفون: Lennart Mucke, Catherine Bedard, Samuel J. Pfaff, Suresh Poda, Michelle R. Arkin, Mark A. Petersen, Jae K. Ryu, Kim M. Baeten, Katerina Akassoglou, Anke Meyer-Franke, Stevin H. Zorn, Kristina Hanspers, Catriona Syme, K.K. Hallenbeck, Kenny K. H. Ang, Alexander R. Pico, Robert B. Nelson, Raymond A. Swanson, Ryan A. Adams, Jeffrey B. Stavenhagen, Shoana L. Sikorski, Scott S. Zamvil, Ioanna Plastira, Veena Menon, Michael R. Machado, Stephen B. Freedman, Lars Østergaard Pedersen, Hiroyuki Hakozaki, Sophia Bardehle, Victoria A. Rafalski, Mark H. Ellisman, Pamela E. Rios Coronado, Justin P. Chan, Dimitrios Davalos, Andrew S. Mendiola

المصدر: Nature immunology, vol 19, iss 11

مصطلحات موضوعية: 0301 basic medicine, Aging, Neurodegenerative, Alzheimer's Disease, chemistry.chemical_compound, Epitopes, Mice, 0302 clinical medicine, Monoclonal, 2.1 Biological and endogenous factors, Immunology and Allergy, Aetiology, biology, Neurodegeneration, Antibodies, Monoclonal, Neurodegenerative Diseases, Hematology, 3. Good health, 5.1 Pharmaceuticals, Neurological, Development of treatments and therapeutic interventions, medicine.symptom, Nicotinamide adenine dinucleotide phosphate, Biotechnology, Multiple Sclerosis, Immunology, Inflammation, Autoimmune Disease, Antibodies, Fibrin, Proinflammatory cytokine, 03 medical and health sciences, Acquired Cognitive Impairment, medicine, Animals, Humans, Neuroinflammation, Innate immune system, business.industry, Neurosciences, Neurotoxicity, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Fibrinogen, medicine.disease, Brain Disorders, Rats, 030104 developmental biology, chemistry, biology.protein, Cancer research, Dementia, business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6af962de7a0dd3774e7f8fdc95dc383
https://pubmed.ncbi.nlm.nih.gov/30323342

المؤلفون: Daniel V. Santi, Thomas Jung, Gary W. Ashley, Lorenz Vogt, Shaun D. Fontaine, Brian R. Hearn, Stefanie Grabulovski, Eric L. Schneider, Samuel J. Pfaff, Verena Strassberger, Ralph Reid

المصدر: Bioconjugate chemistry. 27(10)

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Hydrodynamic radius, Chemistry, Organic Chemistry, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Cleavage (embryo), Molecular biology, 03 medical and health sciences, Subcutaneous injection, 030104 developmental biology, Pharmacokinetics, Covalent bond, Drug delivery, PEG ratio, Biophysics, Linker, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5059bca5985758cc1f210f063f21f15c
https://pubmed.ncbi.nlm.nih.gov/27657443

المؤلفون: Robert J. Fletterick, Samuel J. Pfaff

المصدر: Journal of Biological Chemistry. 285:15256-15267

مصطلحات موضوعية: Hormone response element, Transcription, Genetic, biology, Binding protein, Molecular Sequence Data, Cell Biology, Biochemistry, DNA binding site, Kinetics, Receptors, Glucocorticoid, Glucocorticoid receptor, Allosteric Regulation, Allosteric enzyme, Nuclear receptor, biology.protein, Humans, Amino Acid Sequence, Binding site, Glucocorticoids, Molecular Biology, Molecular Biophysics, Protein Binding, Transcription Factors, Binding domain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4311249d2e4c835d99d8c841f3d096ed
https://doi.org/10.1074/jbc.m110.108118

المؤلفون: Pamela M. England, Robert J. Fletterick, Eva Estébanez-Perpiñá, Ning Bao, Justin D. Blethrow, Leslie A. Cruz, Sabine Borngraeber, Samuel J. Pfaff

المصدر: Journal of Medicinal Chemistry. 51:5856-5860

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Nitro compound, AMPA receptor, Crystallography, X-Ray, Mass Spectrometry, Article, Drug Discovery, Receptors, AMPA, Binding site, Receptor, chemistry.chemical_classification, Binding Sites, Molecular Structure, biology, musculoskeletal, neural, and ocular physiology, Active site, Nitro Compounds, nervous system, chemistry, Covalent bond, Synaptic plasticity, Quinolines, Excitatory Amino Acid Antagonists, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbd0417e8cc9e4a1b6e51d79cac7e7b
https://doi.org/10.1021/jm701517b

المؤلفون: Samuel J, Pfaff, Michael S, Chimenti, Mark J S, Kelly, Michelle R, Arkin

المصدر: Methods in molecular biology (Clifton, N.J.). 1278

مصطلحات موضوعية: Models, Molecular, Small Molecule Libraries, Magnetic Resonance Spectroscopy, Drug Discovery, Biophysics, Computer-Aided Design, Humans, Protein Interaction Maps, Surface Plasmon Resonance, Crystallography, X-Ray

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::81d518d040b01ee8da02f981966b156d
https://pubmed.ncbi.nlm.nih.gov/25859978

المؤلفون: Mark J. S. Kelly, Michael S. Chimenti, Michelle R. Arkin, Samuel J. Pfaff

المصدر: Methods in Molecular Biology ISBN: 9781493924240

مصطلحات موضوعية: Fragment (logic), Chemistry, Computational biology, Surface plasmon resonance, Protein–protein interaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5d5bc7f8f8a1e1969ef31fc81edc4fa2
https://doi.org/10.1007/978-1-4939-2425-7_39

المؤلفون: Benjamin M. Buehrer, Hanne Grøn, Eugene Hur, Samuel J. Pfaff, E. Sturgis Payne, Robert J. Fletterick

المساهمون: Ueli Schibler

المصدر: PLoS biology, vol 2, iss 9
PLoS Biology
PLoS Biology, Vol 2, Iss 9, p E274 (2004)

مصطلحات موضوعية: Male, Secondary, Time Factors, Protein Conformation, Amino Acid Motifs, Sequence Homology, Plasma protein binding, Molecular Biology/Structural Biology, Crystallography, X-Ray, Medical and Health Sciences, Protein Structure, Secondary, Androgen, Nuclear Receptor Coactivator 2, 0302 clinical medicine, Protein structure, Glucocorticoid, Homo (Human), Receptors, Biology (General), Cancer, Oncogene Proteins, 0303 health sciences, Crystallography, General Neuroscience, Prostate Cancer, Intracellular Signaling Peptides and Proteins, Thyroid Hormone Receptors beta, LIM Domain Proteins, Biological Sciences, Cell biology, Gene Expression Regulation, Neoplastic, DNA-Binding Proteins, Amino Acid, Biochemistry, Receptors, Estrogen, Receptors, Androgen, 030220 oncology & carcinogenesis, General Agricultural and Biological Sciences, Research Article, Protein Binding, Urologic Diseases, Protein Structure, QH301-705.5, Molecular Sequence Data, Nuclear Receptor Coactivators, Nerve Tissue Proteins, Biology, DNA-binding protein, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Receptors, Glucocorticoid, Leucine, Peptide Library, Coactivator, Genetics, Humans, Amino Acid Sequence, Transcription factor, 030304 developmental biology, Neoplastic, General Immunology and Microbiology, Sequence Homology, Amino Acid, Agricultural and Veterinary Sciences, Prostatic Neoplasms, Surface Plasmon Resonance, Estrogen, Androgen receptor, Cytoskeletal Proteins, Kinetics, Nuclear receptor, Gene Expression Regulation, Nuclear receptor coactivator 2, X-Ray, Peptides, Carrier Proteins, Transcription Factors, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21941fbbc52d6f6027f8858e514e71c1
https://escholarship.org/uc/item/4m51f66p