المؤلفون: Naglaa M. Ahmed, Mosaad S. Mohamed, Samir M. Awad, Neama A. Abd El-tawab, Mohamed S. Gaballah, Ahmed M. Said

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)

مصطلحات موضوعية: Pyrimidine, anticancer, Bax, Bcl2, p53, Caspase3, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/1e450a1d34db43c69c584854860172db

المؤلفون: Rania H. Abd El-Hameed, Mosaad S. Mohamed, Samir M. Awad, Bardes B. Hassan, Marwa Abd El-Fattah Khodair, Yara E. Mansour

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1, Pp 405-422 (2023)

مصطلحات موضوعية: Benzocoumarin, apoptosis, cell cycle arrest, AML, HL-60, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

URL الوصول: https://doaj.org/article/2b6c97a1264b4ea89425950243b2a360

المؤلفون: Zainab M. Khoder, Mosaad S. Mohamed, Samir M. Awad, Amal F. Gharib, Omnia Aly, Marwa Abd El-Fattah Khodair, Samar S. Fatahala, Rania H. Abd El-Hameed

المصدر: Molecules, Vol 29, Iss 19, p 4697 (2024)

مصطلحات موضوعية: chromenopyrimidine, NCI-assay, cytotoxicity, molecular docking, Bcl-2/Mcl-1 assay, apoptosis, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/29/19/4697; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/885728ae13ad40c68a2cc42ea619e13e

المؤلفون: Yasser M. Zohny, Samir M. Awad, Maha A. Rabie, Omar Awad Alsaidan

المصدر: Molecules, Vol 28, Iss 12, p 4869 (2023)

مصطلحات موضوعية: 3,4-dihydropyrimidin-2(1H)ones, nifedipine isosters, antihypertensive, calcium channel blocking, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/12/4869; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/fa41e8f2662249daa32f4e084bdb4d95

المؤلفون: Naglaa M. Ahmed, Ahmed H. Lotfallah, Mohamed S. Gaballah, Samir M. Awad, Moustafa K. Soltan

المصدر: Molecules, Vol 28, Iss 4, p 1925 (2023)

مصطلحات موضوعية: sulfonamides, antioxidant, DPPH, 15-LOX, molecular docking, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/4/1925; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/bf95a9407d03493ab3dd5dc9b64ce779

المؤلفون: Yasser M. Zohny, Samir M. Awad, Maha A. Rabie, Omar A. Al-Saidan

المصدر: Molecules, Vol 28, Iss 2, p 784 (2023)

مصطلحات موضوعية: antihypertensive agents, calcium channel blockers, dihydropyrimidins, cardiovascular diseases, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/2/784; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/651a8d719245434d8374130e38948ebf

المؤلفون: Samir M. Awad, Yasser M. Zohny, Sahar A. Ali, Shahenda Mahgoub, Ahmed M. Said

المصدر: Molecules, Vol 23, Iss 11, p 2913 (2018)

مصطلحات موضوعية: hyperthyroidism, thiouracil, pyrimidine, antithyroid, PTU, LPO, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/23/11/2913; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/e827e0896c374f7685135dea8197b7a5

المؤلفون: Amira Ibrahim Sayed, Samir M. Awad, Mosaad S. Mohamed

المصدر: Molecules, Vol 15, Iss 3, Pp 1882-1890 (2010)

مصطلحات موضوعية: pyrimidine, 6-amino-2-thioxo-1H-pyrimidine-4-one, antimicrobial, anti-inflammatory, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/15/3/1882/; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/0f7ad2ab91a5483a8e727c0837501dbb

المؤلفون: Samar S. Fatahala, Amira I. Sayed, Shahenda Mahgoub, Heba Taha, Mohamed-I kotb El-Sayed, Mohamed F. El-Shehry, Samir M. Awad, Rania H. Abd El-Hameed

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 21; Pages: 11957

مصطلحات موضوعية: sulfonamides, cytotoxicity, apoptosis, cell cycle, CDK2, molecular docking

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pharmacology; https://dx.doi.org/10.3390/ijms222111957

الاتاحة: https://doi.org/10.3390/ijms222111957

المؤلفون: Samir Y. Abbas, Maha M. Abd El-Aziz, Samir M. Awad, Mosaad S. Mohamed

المصدر: Synthetic Communications. 53:68-75

مصطلحات موضوعية: Organic Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bfa1baa80b15f6f5273e236b136b58d
https://doi.org/10.1080/00397911.2022.2150086

المؤلفون: Rania H. Abd El-Hameed, Mosaad S. Mohamed, Samir M. Awad, Marwa Abd El-Fattah Khodair

المصدر: Anti-Cancer Agents in Medicinal Chemistry. 21:963-986

مصطلحات موضوعية: Cancer Research, Cell Survival, Antineoplastic Agents, Tubulin Polymerization Inhibitors, Structure-Activity Relationship, Then test, Derivative (finance), Humans, Cytotoxic T cell, Benzopyrans, Spectral analysis, Protein Kinase Inhibitors, Cell Proliferation, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Sorafenib, Combinatorial chemistry, Tubulin Modulators, ErbB Receptors, Molecular Docking Simulation, Enzyme, Molecular Medicine, Drug Screening Assays, Antitumor, Colchicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6348d08811b1a4858f5c4ae8051f63
https://doi.org/10.2174/1871520620666200925103742

المؤلفون: Samir M. Awad, Shahira Nofal, Naglaa Mohamed Ahmed

المصدر: Journal of Pharmaceutical Research International. :49-67

مصطلحات موضوعية: biology, Pyrimidine, medicine.drug_class, Ibuprofen, Combinatorial chemistry, Enzyme assay, Anti-inflammatory, In vitro, chemistry.chemical_compound, chemistry, Docking (molecular), biology.protein, medicine, Potency, IC50, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ab81566639fe3474baad97eae01a300b
https://doi.org/10.9734/jpri/2020/v32i2230771

المؤلفون: Ahmed M. Said, Naglaa Mohamed Ahmed, Shahenda Mahgoub, Sahar A. Ali, Samir M. Awad, Heba Taha

المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 847-863 (2020)

مصطلحات موضوعية: Male, Models, Molecular, antioxidant activity, RM1-950, Pyrazole, Nitric Oxide, medicine.disease_cause, 01 natural sciences, Antioxidants, Structure-Activity Relationship, chemistry.chemical_compound, Picrates, Lipoxygenase Inhibitors, Superoxides, Drug Discovery, scavenging activity, medicine, Animals, Arachidonate 15-Lipoxygenase, Humans, Rats, Wistar, Biological evaluation, hybrids, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Low toxicity, 010405 organic chemistry, Chemistry, Biphenyl Compounds, General Medicine, Combinatorial chemistry, Rats, 0104 chemical sciences, 15-lipoxygenase inhibitors, 010404 medicinal & biomolecular chemistry, Design synthesis, Drug Design, Pyrazoles, Therapeutics. Pharmacology, Oxidative stress, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1482baf1b91139f2d00b7ed7d9ec48f9
https://doi.org/10.1080/14756366.2020.1742116

المؤلفون: Shahenda, Mahgoub, Samar S, Fatahala, Amira I, Sayed, Hanaa B, Atya, Mohamed F, El-Shehry, Hala, Afifi, Samir M, Awad, Rania H Abd, El-Hameed, Heba, Taha

المصدر: Bioorganic Chemistry. 128:106092

مصطلحات موضوعية: Dipeptidyl-Peptidase IV Inhibitors, Diabetes Mellitus, Type 2, SARS-CoV-2, Organic Chemistry, Drug Discovery, Humans, Hypoglycemic Agents, Pyrimidinones, Molecular Biology, Biochemistry, Antioxidants, COVID-19 Drug Treatment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69805331d8af176400c5b9a2afff6727
https://doi.org/10.1016/j.bioorg.2022.106092

المؤلفون: Mohamed F. El-Shehry, Mohamed-I Kotb El-Sayed, Yara E. Mansour, Shahenda Mahgoub, Samir M. Awad, Samar S. Fatahala

المصدر: Bioorganic Chemistry

مصطلحات موضوعية: Coronavirus disease 2019 (COVID-19), medicine.drug_class, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Angiotensin-Converting Enzyme Inhibitors, Calcium channel blocker, Pharmacology, Bioisosters, THP‐1 cells, Biochemistry, Antiviral Agents, Anti-inflammatory, Article, Nifedipine, Drug Discovery, medicine, Receptor Inhibition, Humans, THP1 cell line, Molecular Biology, CCB, Antihypertensive Agents, ComputingMethodologies_COMPUTERGRAPHICS, Chemistry, SARS-CoV-2, Calcium channel, Organic Chemistry, Anti-Inflammatory Agents, Non-Steroidal, COVID-19, Calcium Channel Blockers, COVID-19 Drug Treatment, ACE2 receptor, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa982926b0224964350feeba03f682f7
https://pubmed.ncbi.nlm.nih.gov/34474305

المؤلفون: Shima Mahmoud Ali, Yara E. Mansour, Samir M. Awad, Samar S. Fatahala

المصدر: Molecules
Volume 26
Issue 10
Molecules, Vol 26, Iss 2988, p 2988 (2021)

مصطلحات موضوعية: 2019-20 coronavirus outbreak, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), viruses, Pharmaceutical Science, Acyclovir, Drug resistance, Herpesvirus 1, Human, medicine.disease_cause, Antiviral Agents, Article, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, QD241-441, Cytopathogenic Effect, Viral, cyclic nucleosides, Drug Discovery, Chlorocebus aethiops, medicine, Structure–activity relationship, Animals, uracil, Aciclovir, Physical and Theoretical Chemistry, antiviral activities, Uridine, Vero Cells, 030304 developmental biology, 0303 health sciences, 030306 microbiology, Organic Chemistry, Uracil, Reference Standards, Virology, Herpes simplex virus, chemistry, Chemistry (miscellaneous), acyclic nucleosides, Vero cell, Molecular Medicine, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f137e9d97186fc8636e6e8d148af6b3
http://europepmc.org/articles/PMC8157375

المؤلفون: Maha A. Rabie, Yasser M. Zohny, Hesham Haffez, Heba Taha, Samir M. Awad

المصدر: Bioorganic chemistry. 104

مصطلحات موضوعية: Cell cycle checkpoint, Cell Survival, Antineoplastic Agents, Apoptosis, 01 natural sciences, Biochemistry, Antioxidants, chemistry.chemical_compound, Pyrimidine analogue, Structure-Activity Relationship, Drug Discovery, Cytotoxic T cell, Humans, Molecular Biology, IC50, Cells, Cultured, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Phosphodiesterase, Fas receptor, 0104 chemical sciences, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Pyrimidines, Thiourea, chemistry, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f5e6e0927828ad781d49244c874dc3
https://pubmed.ncbi.nlm.nih.gov/32911199

المؤلفون: Saif M. Hassan, Ram B Singh, Mahmood J. Jawad, Najah R. Hadi, Samir M. Awad, Jaipaul Singh, Salam W Ahjel

المصدر: Medical Archives

مصطلحات موضوعية: 0301 basic medicine, NF-E2-Related Factor 2, Pneumonia, Viral, ACE2, Review, nCOVID-19, NF-κB, Alveolar cells, 03 medical and health sciences, chemistry.chemical_compound, Betacoronavirus, 0302 clinical medicine, Downregulation and upregulation, Viral entry, Gene expression, medicine, Humans, Receptor, Lung, Pandemics, business.industry, Activator (genetics), SARS-CoV-2, F410, COVID-19, ROS, General Medicine, respiratory system, Pulmonary Alveoli, 030104 developmental biology, medicine.anatomical_structure, chemistry, Nrf2 activators, Apoptosis, Alveolar Epithelial Cells, Cancer research, RIG-1, business, Coronavirus Infections, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa70a1d3325b94338c305d64f6d6b92

المؤلفون: Mosaad S. Mohamed, Samir M. Awad, Amira Ibrahim Sayed

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.mdpi.com/1420-3049/15/3/1882/pdf/.

مصطلحات موضوعية: pyrimidine, 6-amino-2-thioxo-1H-pyrimidine-4-one, antimicrobial, antiinflammatory

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.429.9583; http://www.mdpi.com/1420-3049/15/3/1882/pdf/

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.429.9583
http://www.mdpi.com/1420-3049/15/3/1882/pdf/

المؤلفون: Ahmed H. Shamroukh, Samir M. Awad, Hatem S. Ali, Aymn E. Rashad

المصدر: Journal of Heterocyclic Chemistry. 51:899-905

مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, chemistry, Carboxylic acid, Reagent, Organic Chemistry, Organic chemistry, Reactivity (chemistry), Pyrazole, Hydrazide, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b241c2a99af86f9a2e3cb1acd1229498
https://doi.org/10.1002/jhet.1724