المؤلفون: Anne M. Fourie, Xiaoli Cheng, Leon Chang, Carrie Greving, Xinyi Li, Beverly Knight, David Polidori, Aaron Patrick, Trpta Bains, Ruth Steele, Samantha J. Allen, Raymond J. Patch, Chengzao Sun, Sandeep Somani, Ashok Bhandari, David Liu, Keith Huie, Shu Li, Michael A. Rodriguez, Xiaohua Xue, Arun Kannan, Teddy Kosoglou, Jonathan P. Sherlock, Jennifer Towne, M. Claire Holland, Nishit B. Modi

المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/a5c225b49e4844578be75fc534d1282c

المؤلفون: Piyali Chatterjee, Laura E Weaver, Karen M Doersch, Shelley E Kopriva, Valorie L Chiasson, Samantha J Allen, Ajay M Narayanan, Kristina J Young, Kathleen A Jones, Thomas J Kuehl, Brett M Mitchell

المصدر: PLoS ONE, Vol 7, Iss 7, p e41884 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3407075?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/a4301ebdaa6e4c609d023b8d1682c41d

المؤلفون: Weixue Wang (1307655), Laurence Mevellec (1693495), Annie Liu (5793302), Geoff Struble (11523741), Robyn Miller (478482), Samantha J. Allen (8926661), Kelly Federowicz (11523744), Berthold Wroblowski (1340940), Jorge Vialard (3469151), Kay Ahn (1523929), Daniel Krosky (4107913)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Cancer, Infectious Diseases, Virology, Computational Biology, Chemical Sciences not elsewhere classified, privileged chemical scaffold, targeting inactive (<, study may represent, length hpk1 utilizing, attenuates kinase autophosphorylation, unphosphorylated inactive forms, cell receptor signaling, 1 , selective hpk1 inhibitors, kinase cascade assays, allosteric hpk1 inhibitor, assays using active, cell signaling, unphosphorylated hpk1, selective inhibitor, inactive conformation, cascade assays, vs <

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_an_Allosteric_Inactive_Conformation-Selective_Inhibitor_of_Full-Length_HPK1_Utilizing_a_Kinase_Cascade_Assay/16743780

الاتاحة: https://doi.org/10.1021/acs.biochem.1c00486.s001

المؤلفون: Aaron A. Thompson, Michael B. Harbut, Pei-Pei Kung, Nathan K. Karpowich, Jeffrey D. Branson, Joanna C. Grant, Deborah Hagan, Heather A. Pascual, Guoyun Bai, Reza Beheshti Zavareh, Heather R. Coate, Bernard C. Collins, Marjorie Côte, Christine F. Gelin, Kelly L. Damm-Ganamet, Hadi Gholami, Adam R. Huff, Luis Limon, Kevin J. Lumb, Puiying A. Mak, Kohki M. Nakafuku, Edmund V. Price, Amy Y. Shih, Mandana Tootoonchi, Nadeem A. Vellore, Jocelyn Wang, Na Wei, Jeannie Ziff, Scott B. Berger, James P. Edwards, Agnès Gardet, Siquan Sun, Jennifer E. Towne, Jennifer D. Venable, Zhicai Shi, Hariharan Venkatesan, Marie-Laure Rives, Sujata Sharma, Brock T. Shireman, Samantha J. Allen

المصدر: Proceedings of the National Academy of Sciences. 120

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a4d48b50bde14ca39eb944d361970a99
https://doi.org/10.1073/pnas.2216342120

المؤلفون: Jorge Vialard, Kelly Federowicz, Geoff Struble, Weixue Wang, Samantha J Allen, Daniel Jason Krosky, Annie Liu, Robyn L. Miller, Berthold Wroblowski, Kay Ahn, Laurence Anne Mevellec

المصدر: Biochemistry. 60(41)

مصطلحات موضوعية: Drug discovery, Kinase, Allosteric regulation, Autophosphorylation, Pyrimidinones, Protein Serine-Threonine Kinases, Triazoles, Phosphoproteins, Biochemistry, Cell biology, High-Throughput Screening Assays, chemistry.chemical_compound, Protein kinase domain, chemistry, Phosphorylation, Humans, Kinome, Adenosine triphosphate, Protein Kinase Inhibitors, Adaptor Proteins, Signal Transducing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a434c7c0f939d41bacdd35042e3e1f1e
https://pubmed.ncbi.nlm.nih.gov/34608799

المؤلفون: Teena M Varghese, Michael F.A. Finley, Samantha J Allen, Paul L. Dudas, Jonathan E Schneeweis

المصدر: SLAS discovery : advancing life sciences RD. 26(1)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Cell, Gene Expression, 010501 environmental sciences, 01 natural sciences, Biochemistry, Analytical Chemistry, 03 medical and health sciences, Genes, Reporter, Drug Discovery, medicine, Cytotoxic T cell, Humans, Luciferase, Viability assay, 0105 earth and related environmental sciences, biology, Chemistry, Small molecule, High-Throughput Screening Assays, 030104 developmental biology, medicine.anatomical_structure, Cytokine, Gene Expression Regulation, Cancer research, biology.protein, Interleukin-23 Subunit p19, Molecular Medicine, Phosphorylation, Antibody, Biotechnology, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a31d677e00fe1099053c8119e05f938
https://pubmed.ncbi.nlm.nih.gov/32484379

المؤلفون: Samantha J, Allen, Kevin J, Lumb

المصدر: Advances in protein chemistry and structural biology. 121

مصطلحات موضوعية: Models, Molecular, Binding Sites, Tumor Necrosis Factor-alpha, Arthritis, Interleukin-17, Antibodies, Monoclonal, Nuclear Receptor Subfamily 1, Group F, Member 3, Interleukin-23, Protein Structure, Secondary, Autoimmune Diseases, Small Molecule Libraries, Gene Expression Regulation, Neoplasms, Protein Interaction Mapping, Humans, Immunologic Factors, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::18dc9e25d067ab3e3bf0576f4d7b5f9f
https://pubmed.ncbi.nlm.nih.gov/32312425

المؤلفون: Brian A. Zabel, Susumu Nakae, Ji-yun Kim, Takao Ohyama, Carsten Alt, Junliang Pan, Hajime Suto, Dulce Soler, Samantha J. Allen, Tracy M. H, Chang Ho Song, Stephen J. Galli, Eugene C. Butcher

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jem.rupress.org/content/205/10/2207.full.pdf.

مصطلحات موضوعية: anaphylaxis

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.6938; http://jem.rupress.org/content/205/10/2207.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.6938
http://jem.rupress.org/content/205/10/2207.full.pdf

المؤلفون: Adam B Weinglass, Nicholas B Hastings, Bradley S Sherborne, Jennifer M. Johnston, Andrew D Howard, Maria Webb, Steven L. Colletti, Clemens Vonrhein, Kevin J. Lumb, Srivanya Tummala, Frank K Brown, Jennifer Hadix, Hubert Josien, Stephen M. Soisson, Guo Yan, Harry R. Chobanian, John Wang, Michael W. Miller, Brande Thomas-Fowlkes, Dawn L. Hall, Jeffrey D. Hermes, Thu Ho, Barbara Pio, Payal R. Sheth, Sujata Sharma, Maria Kornienko, Samantha J Allen, Sangita B. Patel, Jerry Di Salvo, Sarah Souza, Gérard Bricogne, Christopher W Plummer, Jun Lu, Noel Byrne

المصدر: Nature Structural & Molecular Biology. 24:570-577

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Binding Sites, biology, Protein Conformation, Allosteric regulation, Cooperativity, Crystallography, X-Ray, Partial agonist, Receptors, G-Protein-Coupled, 03 medical and health sciences, Transmembrane domain, 030104 developmental biology, Allosteric Regulation, Allosteric enzyme, Biochemistry, Structural Biology, Free fatty acid receptor 1, biology.protein, Free fatty acid receptor, Biophysics, Humans, Binding site, Molecular Biology, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4bc0224021f59b552cc8f44381dfe9
https://doi.org/10.1038/nsmb.3417

المؤلفون: Kevin J. Lumb, Samantha J Allen

المصدر: Advances in Protein Chemistry and Structural Biology ISBN: 9780128168462

مصطلحات موضوعية: Protein therapeutics, Structural biology, Interleukin 23, Interleukin 17, Computational biology, Biology, Small molecule, Protein–protein interaction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ecdecf790171ac6068f25f58c9972cd1
https://doi.org/10.1016/bs.apcsb.2019.12.006

المؤلفون: Stacy Wong, Robert A. Weber, Douglas S. Fornfeist, Samantha J. Allen

المصدر: Journal of surgical education. 77(3)

مصطلحات موضوعية: medicine.medical_specialty, Students, Medical, Positive correlation, Education, Correlation, 03 medical and health sciences, Patient safety, 0302 clinical medicine, medicine, Humans, Medical physics, 030212 general & internal medicine, Technical skills, Rank correlation, Surgeons, Internship and Residency, Resident education, Hand surgery, Hand, Orthopedics, 030220 oncology & carcinogenesis, Orthopedic surgery, Surgery, Female, Clinical Competence, Psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd583868dff972373575bb48da4b162
https://pubmed.ncbi.nlm.nih.gov/31954663

المؤلفون: Nathaniel L. Elsen, Zangwei Xu, Peter J. Dandliker, Peter Saradjian, Keith W. Rickert, Berengere Sauvagnat, Nadya Smotrov, Dawn L. Hall, Elliott B. Nickbarg, Yiping Chen, Sujata Sharma, Kevin J. Lumb, Maria Kornienko, Noel Byrne, Chad Chamberlin, Christine Andrews, Samantha J Allen, Ilona Kariv, Jennifer M. Shipman, Patrick J. Curran, Kevin G. Coleman, Beutel Bruce A, Rachael E. Ford, Victoria Kutilek, Andrew Hashke, Rafael Fernandez, Tianxiao Sun, Matthew Richards, Ryan Boinay

المصدر: SLAS Discovery. 21:608-619

مصطلحات موضوعية: 0301 basic medicine, High-throughput screening, Phenotypic screening, Cell, Druggability, Computational biology, Biology, Ligands, Bioinformatics, 01 natural sciences, Biochemistry, Mass Spectrometry, Analytical Chemistry, Structure-Activity Relationship, 03 medical and health sciences, Drug Discovery, medicine, TNF Receptor-Associated Factor 5, Reverse pharmacology, 010405 organic chemistry, Drug discovery, NF-kappa B, Transcription Factor RelA, Ligand (biochemistry), Phenotype, High-Throughput Screening Assays, 0104 chemical sciences, 030104 developmental biology, medicine.anatomical_structure, Molecular Medicine, Protein Binding, Signal Transduction, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321009edd98ca17a57d26928e293e5e3
https://doi.org/10.1177/1087057116637353

المؤلفون: Arjun Saha, Annie X. Liu, Samantha J Allen, Teena M Varghese, Michael D. Hack, Taraneh Mirzadegan

المصدر: Journal of chemical information and modeling. 58(10)

مصطلحات موضوعية: 0301 basic medicine, Drug candidate, General Chemical Engineering, media_common.quotation_subject, Chemistry, Pharmaceutical, Drug Evaluation, Preclinical, Small Molecule Libraries, General Chemistry, Library and Information Sciences, Data science, Chemical space, Computer Science Applications, High-Throughput Screening Assays, 03 medical and health sciences, 030104 developmental biology, Drug Discovery, Quality (business), Throughput (business), Software, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3005dae336d7eccd61e7169f0cce2531
https://pubmed.ncbi.nlm.nih.gov/30204440

المؤلفون: Kevin J. Lumb, Stephen M. Soisson, Jennifer M. Shipman, Gopal Parthasarathy, Dawn L. Hall, Scott A. Johnson, Keith W. Rickert, Rachael E. Ford, Ronald E. Diehl, Samantha J Allen, Paul Zuck, Paul L. Darke, Sanjeev Munshi, John C. Reid

المصدر: Journal of Biological Chemistry. 290:20360-20373

مصطلحات موضوعية: inorganic chemicals, Models, Molecular, G-Protein-Coupled Receptor Kinase 4, Protein Conformation, Molecular Sequence Data, Mitogen-activated protein kinase kinase, Biology, Crystallography, X-Ray, environment and public health, Biochemistry, Substrate Specificity, MAP2K7, Humans, Amino Acid Sequence, Phosphorylation, Kinase activity, Molecular Biology, Sequence Homology, Amino Acid, MAP kinase kinase kinase, Autophosphorylation, Cyclin-dependent kinase 2, Cyclin-dependent kinase 3, Cell Biology, Cell biology, enzymes and coenzymes (carbohydrates), Protein Structure and Folding, Hypertension, biology.protein, bacteria, Cyclin-dependent kinase 9, biological phenomena, cell phenomena, and immunity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206a2a57c447e93465670375d12ebb66
https://doi.org/10.1074/jbc.m115.648907

المؤلفون: Joseph R. Sharkey, Samantha J. Allen, M. Renée Umstattd Meyer

المصدر: Journal of health care for the poor and underserved. 27(2)

مصطلحات موضوعية: Parental support, media_common.quotation_subject, Physical fitness, Physical activity, Overweight, Developmental psychology, 03 medical and health sciences, Social support, 0302 clinical medicine, Perception, Mexican Americans, Medicine, Humans, 030212 general & internal medicine, Child, Exercise, Mexico, media_common, 030505 public health, business.industry, Mexican origin, Public Health, Environmental and Occupational Health, medicine.disease, Obesity, Texas, Female, medicine.symptom, 0305 other medical science, business, Social psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410da8a6e7a17851b134359ff7cccc02
https://pubmed.ncbi.nlm.nih.gov/27180703

المؤلفون: Brian A. Zabel, Luis A. Zuniga, Samantha J. Allen, Brent Johnston, Tracy M. Handel, David G. Guido, Ji-Yun Kim, Takao Ohyama, Eugene C. Butcher

المصدر: Experimental Hematology. 34:1106-1114

مصطلحات موضوعية: Cancer Research, Molecular Sequence Data, CMKLR1, Receptors, G-Protein-Coupled, Proinflammatory cytokine, Mice, Transforming Growth Factor beta, Genetics, Animals, Humans, Chemerin, Macrophage, Amino Acid Sequence, Receptor, Antigen-presenting cell, Molecular Biology, biology, Macrophages, Toll-Like Receptors, Antibodies, Monoclonal, Dendritic Cells, Cell Biology, Hematology, Cell biology, Integrin alpha M, Immunology, biology.protein, Intercellular Signaling Peptides and Proteins, Receptors, Chemokine, Chemokines, Ex vivo

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd29dce8507471549cda1ef782e48e27
https://doi.org/10.1016/j.exphem.2006.03.011

المؤلفون: Brian A. Zabel, Tracy M. Handel, Takao Ohyama, Joanna Cichy, Eugene C. Butcher, Samantha J. Allen, Luis A. Zuniga

المصدر: Experimental Hematology. 34:1021-1032

مصطلحات موضوعية: Cancer Research, Proteases, Dipeptidyl Peptidase 4, Inflammation, Biology, ADAM10 Protein, Structure-Activity Relationship, Immune system, Genetics, medicine, Leukocyte degranulation, Animals, Humans, Macrophage, Molecular Biology, Chemotactic Factors, Effector, Monokines, Membrane Proteins, Chemotaxis, Cell Biology, Hematology, Macrophage Inflammatory Proteins, Chemokine CXCL12, Immunity, Innate, Cell biology, Complement system, ADAM Proteins, Chemotaxis, Leukocyte, Biochemistry, Chemokines, CC, Receptors, Chemokine, Amyloid Precursor Protein Secretases, medicine.symptom, Chemokines, CXC, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e24fa46453f30d142b3e72ecd38c859
https://doi.org/10.1016/j.exphem.2006.05.003

المؤلفون: Tracy M. Handel, Damon J. Hamel, Samantha J. Allen

المصدر: Cytokine. 55(2)

مصطلحات موضوعية: Chemokine, Recombinant Fusion Proteins, Immunology, CCL3, Biotin, CCL7, Ligands, Biochemistry, Chromatography, Affinity, Article, Chemokine receptor, Radioligand Assay, Immunology and Allergy, Humans, CCL14, Chemokine CCL7, Receptor, Molecular Biology, Chemokine CCL3, Fluorescent Dyes, biology, Interleukin-8, Hematology, Ligand (biochemistry), In vitro, Chemokines, CC, biology.protein, Chemokines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8fff91c2597b79009ddb7dec8a5a8c
https://pubmed.ncbi.nlm.nih.gov/21632261

المؤلفون: Tracy M. Handel, Jan Potempa, Hua Tu, Andrzej Kozik, Brian A. Zabel, Tomasz Kantyka, Paulina Kulig, Anna Stefanska, Samantha J. Allen, Magdalena Banaś, Eugene C. Butcher, Agnieszka Chyra, Joanna Cichy

المصدر: The Journal of Immunology

مصطلحات موضوعية: Cathepsin L, medicine.medical_treatment, Cathepsin K, Immunology, CHO Cells, Biology, CMKLR1, Article, Cathepsin B, Substrate Specificity, Cathelicidin, 03 medical and health sciences, Cricetulus, 0302 clinical medicine, Cell Movement, Cysteine Proteases, Cricetinae, medicine, Animals, Humans, Immunology and Allergy, Chemerin, Chemoattractant activity, 030304 developmental biology, Antibacterial agent, Cathepsin, 0303 health sciences, Chemotactic Factors, Dendritic Cells, Recombinant Proteins, Anti-Bacterial Agents, 3. Good health, Biochemistry, 030220 oncology & carcinogenesis, biology.protein, Intercellular Signaling Peptides and Proteins, Receptors, Chemokine, Cystatin, Chemokines

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e109a670472bfcd1309c9acdb0f7e6
https://ruj.uj.edu.pl/xmlui/handle/item/61591

المؤلفون: Richard Horuk, Tracy M. Handel, Sofia Ribeiro, Samantha J. Allen

مصطلحات موضوعية: CCR1, Detergents, Molecular Sequence Data, Receptors, CCR1, C-C chemokine receptor type 7, C-C chemokine receptor type 6, Biology, CCR8, CXCR3, Article, Protein Structure, Secondary, Cell Line, Chemokine receptor, Biochemistry, Chemokine binding, Chemokines, CC, Humans, CXC chemokine receptors, Amino Acid Sequence, Chemokines, Micelles, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc78a2b4ad103d604390218e481cc0e4
https://europepmc.org/articles/PMC2706832/