المؤلفون: Krzysztof Kamiński, Jolanta Obniska, Sabina Rzepka

المصدر: Bioorganic & Medicinal Chemistry. 20:4872-4880

مصطلحات موضوعية: Male, Phenytoin, medicine.medical_treatment, Clinical Biochemistry, Antiepileptic drug, Administration, Oral, Succinimides, Pharmaceutical Science, Mice, Inbred Strains, Pharmacology, Biochemistry, Pyrrolidine, Mannich Bases, Rats, Sprague-Dawley, Mice, chemistry.chemical_compound, Seizures, Oral administration, In vivo, Drug Discovery, medicine, Animals, Molecular Biology, Electroshock, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Neurotoxicity, medicine.disease, Rats, Maximal electroshock, Anticonvulsant, Pentylenetetrazole, Molecular Medicine, Anticonvulsants, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca3039e22b2b7a0c6b0f01fec92c6317
https://doi.org/10.1016/j.bmc.2012.05.032

المؤلفون: Jolanta Obniska, Krzysztof Kamiński, Sabina Rzepka

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:5800-5803

مصطلحات موضوعية: Time Factors, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Drug Evaluation, Preclinical, Administration, Oral, Succinimides, Pharmaceutical Science, Convulsants, Phenylpiperazine, Motor Activity, Biochemistry, Piperazines, Pyrrolidine, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Succinimide, Seizures, Drug Discovery, medicine, Animals, High activity, Molecular Biology, Electroshock, Trifluoromethyl, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Rats, Maximal electroshock, Anticonvulsant, Drug Design, Phenytoin, Ethosuximide, Pentylenetetrazole, Molecular Medicine, Anticonvulsants, Injections, Intraperitoneal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fc33384a3540a5fb9e0658f59f8e62
https://doi.org/10.1016/j.bmcl.2011.07.118

المؤلفون: Beata Wiklik, Krzysztof Kamiński, Iwona Chlebek, Sabina Rzepka, Jolanta Obniska

مصطلحات موضوعية: Male, Pyrrolidines, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Status epilepticus, Motor Activity, Pharmacology, Biochemistry, Mannich Bases, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, Epilepsy, Seizures, Oral administration, In vivo, Drug Discovery, medicine, Animals, Cytochrome P-450 CYP3A, Humans, Molecular Biology, ED50, Electroshock, CYP3A4, Chemistry, Organic Chemistry, medicine.disease, Rats, Disease Models, Animal, Anticonvulsant, Drug Design, Toxicity, Microsomes, Liver, Cytochrome P-450 CYP3A Inhibitors, Pentylenetetrazole, Molecular Medicine, Anticonvulsants, medicine.symptom, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae617f96375d74741e052e32da44c38
https://ruj.uj.edu.pl/xmlui/handle/item/123844