نتائج البحث - "Saïd M. Sebti"

1

Academic Journal

GSK3 suppression upregulates β-catenin and c-Myc to abrogate KRas-dependent tumors

المؤلفون: Aslamuzzaman Kazi, Shengyan Xiang, Hua Yang, Daniel Delitto, José Trevino, Rays H. Y. Jiang, Muhammad Ayaz, Harshani R. Lawrence, Perry Kennedy, Saïd M. Sebti

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e4dd4e549d124d48b1ca42f85db738ff

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2

Academic Journal

Supplementary Table S1 from Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors

المؤلفون: Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M.V., Bogos Agianian, Martin Garcia Chavez, Vignesh Vudatha, Rui Wang, Rajanikanth Vangipurapu, Liwei Chen, Perry Kennedy, Karthikeyan Subramanian, Jonathan C.K. Quirke, Francisca Beato, Patrick W. Underwood, Jason B. Fleming, Jose Trevino, Paul J. Hergenrother, Evripidis Gavathiotis, Said M. Sebti

مصطلحات موضوعية: Cancer, Cancer Biology, Molecular and Cellular Biology, Therapeutic Research and Development, Small Molecule Agents, Gastrointestinal Cancers, Pancreatic cancer, Oncogenes & Tumor Suppressors, Kras, Chemistry & Chemical Biology, Cell Signaling, Guanine nucleotide binding proteins and effectors

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Table_S1_from_Discovery_of_KRB-456_a_KRAS_G12D_Switch-I_II_Allosteric_Pocket_Binder_That_Inhibits_the_Growth_of_Pancreatic_Cancer_Patient-derived_Tumors/24913478

الاتاحة: https://doi.org/10.1158/2767-9764.24913478.v1
https://figshare.com/articles/journal_contribution/Supplementary_Table_S1_from_Discovery_of_KRB-456_a_KRAS_G12D_Switch-I_II_Allosteric_Pocket_Binder_That_Inhibits_the_Growth_of_Pancreatic_Cancer_Patient-derived_Tumors/24913478

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3

Academic Journal

Supplementary Figure Legends from Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors

المؤلفون: Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M.V., Bogos Agianian, Martin Garcia Chavez, Vignesh Vudatha, Rui Wang, Rajanikanth Vangipurapu, Liwei Chen, Perry Kennedy, Karthikeyan Subramanian, Jonathan C.K. Quirke, Francisca Beato, Patrick W. Underwood, Jason B. Fleming, Jose Trevino, Paul J. Hergenrother, Evripidis Gavathiotis, Said M. Sebti

مصطلحات موضوعية: Cancer, Cancer Biology, Molecular and Cellular Biology, Therapeutic Research and Development, Small Molecule Agents, Gastrointestinal Cancers, Pancreatic cancer, Oncogenes & Tumor Suppressors, Kras, Chemistry & Chemical Biology, Cell Signaling, Guanine nucleotide binding proteins and effectors

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Figure_Legends_from_Discovery_of_KRB-456_a_KRAS_G12D_Switch-I_II_Allosteric_Pocket_Binder_That_Inhibits_the_Growth_of_Pancreatic_Cancer_Patient-derived_Tumors/24913484

الاتاحة: https://doi.org/10.1158/2767-9764.24913484.v1
https://figshare.com/articles/journal_contribution/Supplementary_Figure_Legends_from_Discovery_of_KRB-456_a_KRAS_G12D_Switch-I_II_Allosteric_Pocket_Binder_That_Inhibits_the_Growth_of_Pancreatic_Cancer_Patient-derived_Tumors/24913484

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4

Academic Journal

Supplementary Methods from Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors

المؤلفون: Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M.V., Bogos Agianian, Martin Garcia Chavez, Vignesh Vudatha, Rui Wang, Rajanikanth Vangipurapu, Liwei Chen, Perry Kennedy, Karthikeyan Subramanian, Jonathan C.K. Quirke, Francisca Beato, Patrick W. Underwood, Jason B. Fleming, Jose Trevino, Paul J. Hergenrother, Evripidis Gavathiotis, Said M. Sebti

مصطلحات موضوعية: Cancer, Cancer Biology, Molecular and Cellular Biology, Therapeutic Research and Development, Small Molecule Agents, Gastrointestinal Cancers, Pancreatic cancer, Oncogenes & Tumor Suppressors, Kras, Chemistry & Chemical Biology, Cell Signaling, Guanine nucleotide binding proteins and effectors

Relation: https://figshare.com/articles/journal_contribution/Supplementary_Methods_from_Discovery_of_KRB-456_a_KRAS_G12D_Switch-I_II_Allosteric_Pocket_Binder_That_Inhibits_the_Growth_of_Pancreatic_Cancer_Patient-derived_Tumors/24913481

الاتاحة: https://doi.org/10.1158/2767-9764.24913481.v1
https://figshare.com/articles/journal_contribution/Supplementary_Methods_from_Discovery_of_KRB-456_a_KRAS_G12D_Switch-I_II_Allosteric_Pocket_Binder_That_Inhibits_the_Growth_of_Pancreatic_Cancer_Patient-derived_Tumors/24913481

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5

Academic Journal

Novel mutant KRAS addiction signature predicts response to the combination of ERBB and MEK inhibitors in lung and pancreatic cancers

المؤلفون: Katarzyna M. Tyc, Aslamuzzaman Kazi, Alok Ranjan, Rui Wang, Said M. Sebti

المصدر: iScience, Vol 26, Iss 3, Pp 106082- (2023)

مصطلحات موضوعية: Cancer, Transcriptomics, Science

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223001591; https://doaj.org/toc/2589-0042; https://doaj.org/article/d36dcf12c3fb495b80f4008e28cd2572

الاتاحة: https://doi.org/10.1016/j.isci.2023.106082
https://doaj.org/article/d36dcf12c3fb495b80f4008e28cd2572

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6

Supp Figures from Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer

المؤلفون: Saïd M. Sebti, José Trevino, John Koomen, Eric A. Welsh, Mokenge Malafa, Jason B. Fleming, Patrick Underwood, Kazim Husain, Terence M. Williams, Bin Fang, Francisca Beato, Hua Yang, Rajanikanth Vangipurapu, Shengyan Xiang, Liwei Chen, Aslamuzzaman Kazi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3c5c7bb40829ed9e2c0a6092ad296a
https://doi.org/10.1158/1078-0432.22480673.v1

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7

Data from Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer

المؤلفون: Saïd M. Sebti, José Trevino, John Koomen, Eric A. Welsh, Mokenge Malafa, Jason B. Fleming, Patrick Underwood, Kazim Husain, Terence M. Williams, Bin Fang, Francisca Beato, Hua Yang, Rajanikanth Vangipurapu, Shengyan Xiang, Liwei Chen, Aslamuzzaman Kazi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5522e5fa9b7383df56badf8e1b5b2172
https://doi.org/10.1158/1078-0432.c.6530501

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8

Supplementary Data from Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer

المؤلفون: Saïd M. Sebti, José Trevino, John Koomen, Eric A. Welsh, Mokenge Malafa, Jason B. Fleming, Patrick Underwood, Kazim Husain, Terence M. Williams, Bin Fang, Francisca Beato, Hua Yang, Rajanikanth Vangipurapu, Shengyan Xiang, Liwei Chen, Aslamuzzaman Kazi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5d61663c85de4f79cf80423cc27a7c
https://doi.org/10.1158/1078-0432.22480658.v1

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9

Supplementary Data from Combination of Farnesyltransferase and Akt Inhibitors Is Synergistic in Breast Cancer Cells and Causes Significant Breast Tumor Regression in ErbB2 Transgenic Mice

المؤلفون: Saïd M. Sebti, Jin Q. Cheng, Andrew D. Hamilton, Domenico Coppola, William J. Fulp, Y. Ann Chen, Kara D. Forinash, Maria E. Balasis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d216809b2095fee2b72c1cb81311aac1
https://doi.org/10.1158/1078-0432.22442673

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10

Data from Combination of Farnesyltransferase and Akt Inhibitors Is Synergistic in Breast Cancer Cells and Causes Significant Breast Tumor Regression in ErbB2 Transgenic Mice

المؤلفون: Saïd M. Sebti, Jin Q. Cheng, Andrew D. Hamilton, Domenico Coppola, William J. Fulp, Y. Ann Chen, Kara D. Forinash, Maria E. Balasis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0895cd4b3d0ea341e7f26ac360ffdb
https://doi.org/10.1158/1078-0432.c.6519345

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11

Supplementary Figure 2 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12283faddd80f040d4fcd387d6eda5d8
https://doi.org/10.1158/0008-5472.22395777

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12

Supplementary Figure 2 from A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Wayne C. Guida, Harshani R. Lawrence, Murali K. Urlam, Hua Yang, Roberta Pireddu, Ying Sun, Xiaolei Zhang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52db33b6be49761e50a20e3b86119d69
https://doi.org/10.1158/0008-5472.22399038.v1

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13

Supplementary Table 2 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010cd8795a78124402a30c017fde77c6
https://doi.org/10.1158/0008-5472.22395765

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14

Supplementary Table 4 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b036d791eed5cc9092b87753bb1603
https://doi.org/10.1158/0008-5472.22395759.v1

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15

Supplementary Table 3 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0b7387632b7e2eb8ac99e920405251
https://doi.org/10.1158/0008-5472.22395762.v1

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16

Supplementary Figure 4 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a41899a6a8e1f8c37629cfa88c9950c
https://doi.org/10.1158/0008-5472.22395771.v1

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17

Supplementary Figure 1 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a25bebf05e5949478030065dfb71a8
https://doi.org/10.1158/0008-5472.22395780.v1

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18

Supplementary Figure 1 from A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Wayne C. Guida, Harshani R. Lawrence, Murali K. Urlam, Hua Yang, Roberta Pireddu, Ying Sun, Xiaolei Zhang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e22dd39cc241e177d3cb8ecf67e1a4
https://doi.org/10.1158/0008-5472.22399041

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19

Supplementary Table 1 from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8dbad2a8b3b4926ca43a3b91fd80fd
https://doi.org/10.1158/0008-5472.22395768.v1

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20

Data from RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer

المؤلفون: Saïd M. Sebti, Nicholas J. Lawrence, Ernst Schönbrunn, Mathew P. Martin, Nan Sun, Ying Sun, Roberta Pireddu, Kara D. Forinash, Ronil A. Patel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef365ddb9c892a1d7f06100c828baad
https://doi.org/10.1158/0008-5472.c.6504393.v1

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