المؤلفون: Gabriel Rocha, Jonathan Ramírez-Cárdenas, M. Carmen Padilla-Pérez, Samuel Walpole, Ridvan Nepravishta, M. Isabel García-Moreno, Elena M. Sánchez-Fernández, Carmen Ortiz Mellet, Jesús Angulo, Juan C. Muñoz-García

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Sociology, Immunology, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, two saturation times, obtain initial slopes, main intermolecular contacts, increasing saturation times, epitope mapping requires, observed nmr tool, powerful analytical technique, std nmr spectroscopy, full analysis using, ), std nmr, , powerful ligand, k <, >< sub, weak affinity, small molecules, pharmaceutical industry, new protocol, long series, important limitation, given macromolecule

Relation: https://figshare.com/articles/journal_contribution/Speeding-up_the_Determination_of_Protein_Ligand_Affinities_by_STD_NMR_The_Reduced_Data_Set_STD_NMR_Approach_rd-STD_NMR_/24926279

الاتاحة: https://doi.org/10.1021/acs.analchem.3c03980.s001
https://figshare.com/articles/journal_contribution/Speeding-up_the_Determination_of_Protein_Ligand_Affinities_by_STD_NMR_The_Reduced_Data_Set_STD_NMR_Approach_rd-STD_NMR_/24926279

المؤلفون: María Jose García-Jiménez, Myriam Torres-Rico, José L. de Paz, Pedro M. Nieto

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3026

مصطلحات موضوعية: carbohydrate–protein interaction, pleiotrophin, chondroitin sulfate, GAG synthesis, transient NMR methods, STD-NMR spectroscopy

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biophysics; https://dx.doi.org/10.3390/ijms23063026

الاتاحة: https://doi.org/10.3390/ijms23063026

المؤلفون: Francesca Berni (11128292), Ermioni Kalfopoulou (11128295), Ana M. Gimeno Cardells (11128298), Filippo Carboni (1565848), Daan van der Es (5663255), Felipe Romero-Saavedra (647854), Diana Laverde (319025), Karmela Miklic (11128301), Suzana Malic (11128304), Tihana L. Rovis (11128307), Stipan Jonjic (139671), Sara Ali (3430022), Herman S. Overkleeft (128584), Cornelis H. Hokke (115502), Angela van Diepen (11128310), Roberto Adamo (544440), Jesús Jiménez-Barbero (1507663), Gijsbert A. van der Marel (7289363), Johannes Huebner (19110), Jeroen D. C. Codée (7319009)

مصطلحات موضوعية: Biotechnology, Ecology, Immunology, Mental Health, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, Monoclonal Antibody, Glycerol phosphate, sugar appendage, findings show, Synthetic Glycerol Phosphate, TA microarrays, case study, ELISA, staphylococcus species, Epitope Recognition, GroP residues, antigenic cell-wall components, molecular-level binding analysis, STD-NMR spectroscopy, antibody, binding site, interaction

Relation: https://figshare.com/articles/journal_contribution/Epitope_Recognition_of_a_Monoclonal_Antibody_Raised_against_a_Synthetic_Glycerol_Phosphate_Based_Teichoic_Acid/14977079

الاتاحة: https://doi.org/10.1021/acschembio.1c00422.s001

المؤلفون: García-Jiménez, María José, Gil-Caballero, Sergio, Maza, Susana, Corzana, Francisco, Juárez-Vicente, Francisco, Miles, Jonathan R, Sakamoto, Kazuma, Kadomatsu, Kenji, García-Domínguez, Mario, de Paz, José L, Nieto, Pedro M

مصطلحات موضوعية: MD, STD NMR spectroscopy, carbohydrate-protein complexes, chondroitin sulfate, midkine, transient NMRspectroscopy, Animals, Chondroitin Sulfates, Glycosaminoglycans, Mice, NIH 3T3 Cells, Oligosaccharides

وصف الملف: application/pdf

Relation: http://hdl.handle.net/10668/18144; PMC8457220; https://doi.org/10.1002/chem.202101674; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457220/pdf

الاتاحة: http://hdl.handle.net/10668/18144
https://doi.org/10.1002/chem.202101674
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457220/pdf

المؤلفون: F. Vasile, M. Panigada, A. Siccardi, D. Potenza, G. Tiana

المساهمون: F. Vasile, M. Panigada, A. Siccardi, D. Potenza, G. Tiana

مصطلحات موضوعية: STD-NMR spectroscopy, influenza virus Hemagglutinin, ligand-protein interaction, transfected cell, antiviral drug discovery, Settore CHIM/06 - Chimica Organica, Settore FIS/03 - Fisica della Materia, Settore MED/17 - Malattie Infettive

Relation: info:eu-repo/semantics/altIdentifier/pmid/29695047; info:eu-repo/semantics/altIdentifier/wos/WOS:000435297000003; volume:19; issue:5; numberofpages:13; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; http://hdl.handle.net/2434/571371; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85046072147

الاتاحة: http://hdl.handle.net/2434/571371
https://doi.org/10.3390/ijms19051267

المؤلفون: F. Vasile, F. Gubinelli, M. Panigada, E. Soprana, A. Siccardi, D. Potenza

المساهمون: F. Vasile, F. Gubinelli, M. Panigada, E. Soprana, A. Siccardi, D. Potenza

مصطلحات موضوعية: STD-NMR spectroscopy, anti-viral drug discovery, influenza-virus hemagglutinin, ligand-protein interaction, transfected cells, Settore CHIM/06 - Chimica Organica

Relation: info:eu-repo/semantics/altIdentifier/pmid/29087468; info:eu-repo/semantics/altIdentifier/wos/WOS:000426834800005; volume:28; issue:1; firstpage:42; lastpage:49; numberofpages:8; journal:GLYCOBIOLOGY; http://hdl.handle.net/2434/560236; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85046107395

الاتاحة: http://hdl.handle.net/2434/560236
https://doi.org/10.1093/glycob/cwx092

المؤلفون: Barbara Hadley, Andrea Maggioni, Angel Ashikov, Christopher J. Day, Thomas Haselhorst, Joe Tiralongo

المصدر: Computational and Structural Biotechnology Journal, Vol 10, Iss 16, Pp 23-32 (2014)

مصطلحات موضوعية: Nucleotide sugar transporters, CMP-sialic acid transporter, Golgi apparatus, Endoplasmic reticulum, STD NMR spectroscopy, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S200103701400004X; https://doaj.org/toc/2001-0370

URL الوصول: https://doaj.org/article/707f2373f3b04b088a5091150e1c94bc

المؤلفون: Hollinger, Martin

مصطلحات موضوعية: Sättigungs-Transfer-Differenz (STD)-NMR Spektroskopie, Oberflächenplasmonenresonanz, Saturation-Transfer-Difference (STD) - NMR spectroscopy, plasmon surface resonance, 540 Chemie, 35.52 Präparative Organische Chemie, Arzneimitteldesign, Geflügelpestvirus, Molekulardesign, Neuraminsäurederivate, ddc:540

URL الوصول: http://nbn-resolving.de/urn:nbn:de:gbv:18-42805
https://ediss.sub.uni-hamburg.de/handle/ediss/2719

المؤلفون: Lotteke J Y M Swier, Anna K. H. Hirsch, Dirk Jan Slotboom, Leticia Monjas, Inda Setyawati

المساهمون: Helmholtz-Institut für pharmazeutische Forschung Saarland, Universitätscampus E9.1, 66123 Saarbrücken, Germany., Chemical Biology 2, Enzymology

المصدر: Chemmedchem
ChemMedChem, 12(20), 1693-1696. WILEY-V C H VERLAG GMBH

مصطلحات موضوعية: Models, Molecular, Stereochemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, Small Molecule Libraries, Bacterial Proteins, transmembrane proteins, Drug Discovery, Dynamic combinatorial chemistry, Combinatorial Chemistry Techniques, flexible protein pockets, Thiamine, General Pharmacology, Toxicology and Pharmaceutics, Integral membrane protein, Pharmacology, dynamic combinatorial chemistry, biology, Molecular Structure, 010405 organic chemistry, Component (thermodynamics), Chemistry, Communication, fungi, Organic Chemistry, Lactococcus lactis, Transporter, Biological Transport, Nuclear magnetic resonance spectroscopy, energy-coupling factor transporter, biology.organism_classification, Transmembrane protein, Communications, 0104 chemical sciences, Protein Subunits, Drug Design, Molecular Medicine, ATP-Binding Cassette Transporters, STD NMR spectroscopy, Carrier Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b9e406cfc92a1a979a5079fcadb571

المؤلفون: Teixeira, João M. C., Dias, David M., Cañada, Javier, Martins, J. A. R., André, João P., Jiménez-Barbero, Jesús, Geraldes, Carlos F. G. C.

مصطلحات موضوعية: Ligand-receptor binding, Glycoconjugates, STD-NMR spectroscopy, MRI contrast agents, Protein-ligand interaction, Compound docking, Saturation transfer difference NMR spectroscopy, Science & Technology

وصف الملف: application/pdf

Relation: info:eu-repo/grantAgreement/FCT/5876-PPCDTI/70063/PT; http://hdl.handle.net/1822/14275

الاتاحة: http://hdl.handle.net/1822/14275
https://doi.org/10.1007/s00775-011-0773-z

المؤلفون: Thomas Peters, Alvaro Mallagaray, Robert Creutznacher, Eric Schulze, Georg Wallmann, Matthias Stein

المصدر: ChemBioChem: A European Journal of Chemical Biology
Chembiochem
Datacite
UnpayWall
ORCID
Microsoft Academic Graph
PubMed Central

مصطلحات موضوعية: ved/biology.organism_classification_rank.species, Binding pocket, long-timescale MD, Bile acid binding, Coat protein, Molecular Dynamics Simulation, 010402 general chemistry, medicine.disease_cause, Ligands, 01 natural sciences, Biochemistry, ensemble docking, Cofactor, Bile Acids and Salts, Molecular recognition, Antigen, medicine, Animals, Humans, Molecular Biology, Nuclear Magnetic Resonance, Biomolecular, Caliciviridae Infections, Binding Sites, biology, Full Paper, 010405 organic chemistry, ved/biology, Chemistry, Organic Chemistry, Norovirus, Full Papers, 0104 chemical sciences, 3. Good health, Protein Structure, Tertiary, chemical shift perturbation, biology.protein, Molecular Medicine, STD NMR spectroscopy, Capsid Proteins, molecular recognition, Dimerization, Murine norovirus, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80eb63e1ac05e40afd58809b79e00afc
https://hdl.handle.net/21.11116/0000-0004-F749-421.11116/0000-0007-AAFD-D

المؤلفون: van Straaten, Karin E., Kuttiyatveeti, Jijin R. A., Sevrain, Charlotte M., Villaume, Sydney A., Jimenez-Barbero, Jesus, Linclau, Bruno, Vincent, Stephane P., Sanders, David A. R.

المصدر: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ; ISSN: 0002-7863 ; ISSN: 1520-5126

مصطلحات موضوعية: Chemistry, HYDROGEN-BOND ACCEPTOR, STD-NMR SPECTROSCOPY, ESCHERICHIA-COLI, CRYSTAL-STRUCTURES, CONFORMATIONAL-CHANGE, ORGANIC FLUORINE, OXIDIZED, STATE, DOMAIN MOTIONS, MECHANISM, GALACTOFURANOSE

Relation: https://biblio.ugent.be/publication/01GMMX8R9275W206QA6QBTBN5B; http://hdl.handle.net/1854/LU-01GMMX8R9275W206QA6QBTBN5B; http://dx.doi.org/10.1021/ja511204p

الاتاحة: https://biblio.ugent.be/publication/01GMMX8R9275W206QA6QBTBN5B
http://hdl.handle.net/1854/LU-01GMMX8R9275W206QA6QBTBN5B
https://doi.org/10.1021/ja511204p

المؤلفون: Ng, Preston S. K., Boehm, Raphael, Hartley-Tassell, Lauren E., Steen, Jason A., Wang, Hui, Lukowski, Samuel W., Hawthorne, Paula L., Trezise, Ann E. O., Coloe, Peter J., Grimmond, Sean M., Haselhorst, Thomas, von Itzstein, Mark, Paton, Adrienne W., Paton, James C., Jennings, Michael P.

مصطلحات موضوعية: N-glycolylneuraminic acid, Anion exchange chromatography, Pulsed amperometric detection, STD NMR spectroscopy, Sialic acid, Acetylneuraminic acid, Binding specificity, Molecular phylogeny, Cell glycolipids, Ligand binding, 1300 Biochemistry, Genetics and Molecular Biology, 1600 Chemistry, 3100 Physics and Astronomy

Relation: orcid:0000-0002-8598-7902; 565526; 1006618; DP120103178; DP130102945; Not set

الاتاحة: https://espace.library.uq.edu.au/view/UQ:352084

المؤلفون: Mondal, Milon, Radeva, Nedyalka, Koester, Helene, Park, Ahyoung, Potamitis, Constantinos, Zervou, Maria, Klebe, Gerhard, Hirsch, Anna K. H.

المصدر: Mondal , M , Radeva , N , Koester , H , Park , A , Potamitis , C , Zervou , M , Klebe , G & Hirsch , A K H 2014 , ' Structure-Based Design of Inhibitors of the Aspartic Protease Endothiapepsin by Exploiting Dynamic Combinatorial Chemistry ' , Angewandte Chemie - International Edition , vol. 53 , no. 12 , pp. 3259-3263 . https://doi.org/10.1002/anie.201309682

مصطلحات موضوعية: dynamic combinatorial chemistry, enzyme inhibitors, STD NMR spectroscopy, structure-based design, X-ray diffraction, DIFFERENCE NMR-SPECTROSCOPY, HYDE SCORING FUNCTION, DRUG DESIGN, X-RAY, NUCLEOPHILIC CATALYSIS, COVALENT CHEMISTRY, LIGAND-BINDING, LIVING CELLS, LIBRARIES, DISCOVERY

Relation: https://research.rug.nl/en/publications/85ec4b0c-95af-45d4-9185-109c8d45df56

الاتاحة: https://hdl.handle.net/11370/85ec4b0c-95af-45d4-9185-109c8d45df56
https://research.rug.nl/en/publications/85ec4b0c-95af-45d4-9185-109c8d45df56
https://doi.org/10.1002/anie.201309682

المؤلفون: Helene Köster, Ahyoung Park, Anna K. H. Hirsch, Milon Mondal, Maria Zervou, Constantinos Potamitis, Gerhard Klebe, Nedyalka Radeva

المساهمون: Chemical Biology 2

المصدر: Angewandte Chemie-International Edition, 53(12), 3259-3263. WILEY-V C H VERLAG GMBH

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Stereochemistry, enzyme inhibitors, NUCLEOPHILIC CATALYSIS, Catalysis, Structure-Activity Relationship, Aspartate protease, X-Ray Diffraction, DIFFERENCE NMR-SPECTROSCOPY, Dynamic combinatorial chemistry, Structure–activity relationship, Aspartic Acid Endopeptidases, Combinatorial Chemistry Techniques, HYDE SCORING FUNCTION, LIVING CELLS, Endothiapepsin, dynamic combinatorial chemistry, Molecular Structure, Chemistry, fungi, General Chemistry, Nuclear magnetic resonance spectroscopy, COVALENT CHEMISTRY, Combinatorial chemistry, LIBRARIES, structure-based design, Biological target, DISCOVERY, Drug Design, LIGAND-BINDING, X-RAY, Structure based, STD NMR spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c53ddf86a505959a91d7cb9297aa0b0
https://pubmed.ncbi.nlm.nih.gov/24532096

المؤلفون: de Talance, Vincent Lemau, Thiery, Emilie, Eppe, Guillaume, El Bkassiny, Sandy, Mortier, Jérémie, Vincent, Stéphane P.

المساهمون: Univ Namur FUNDP, Acad Louvain, Dept Chim, Lab Chim Bioorgan, B-5000 Namur, Belgium, Partenaires INRAE, Université de Namur Namur (UNamur)

المصدر: ISSN: 0732-8303.

مصطلحات موضوعية: Lactone, Anomeric oxidation, UDP-GALACTOPYRANOSE MUTASE, STD-NMR SPECTROSCOPY, MYCOBACTERIUM-TUBERCULOSIS, CHEMICAL-SYNTHESIS, INHIBITORS, ACIDS, OXIDATION, MECHANISM, BINDING, Galactofuranose, Arabinogalactan, CONVENIENT SYNTHESIS, [SDV]Life Sciences [q-bio]

Relation: hal-02646233; https://hal.inrae.fr/hal-02646233; PRODINRA: 355386; WOS: 000299003800013

الاتاحة: https://hal.inrae.fr/hal-02646233
https://doi.org/10.1080/07328303.2011.616273

المؤلفون: Stéphane P. Vincent, Sandy El Bkassiny, Guillaume Eppe, Vincent Lemau de Talancé, Jérémie Mortier, Emilie Thiery

المساهمون: Univ Namur FUNDP, Acad Louvain, Dept Chim, Lab Chim Bioorgan, B-5000 Namur, Belgium, Partenaires INRAE, Université de Namur [Namur] (UNamur)

المصدر: Journal of Carbohydrate Chemistry
Journal of Carbohydrate Chemistry, Taylor & Francis, 2011, 30 (7-9), pp.605-617. ⟨10.1080/07328303.2011.616273⟩

مصطلحات موضوعية: MECHANISM, Arabinogalactan, [SDV]Life Sciences [q-bio], Ether, OXIDATION, 01 natural sciences, Biochemistry, Anomeric oxidation, 03 medical and health sciences, chemistry.chemical_compound, BINDING, Organic chemistry, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Chemistry, Galactofuranose, Organic Chemistry, STD-NMR SPECTROSCOPY, Lactone, ACIDS, 0104 chemical sciences, CONVENIENT SYNTHESIS, Yield (chemistry), MYCOBACTERIUM-TUBERCULOSIS, UDP-GALACTOPYRANOSE MUTASE, CHEMICAL-SYNTHESIS, INHIBITORS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275c0d89a123f64efb8961f05a0c1af0
https://hal.inrae.fr/hal-02646233

المؤلفون: Predrag Novak, Predrag Tepeš, Vedrana Lazić

المصدر: Croatica Chemica Acta
Volume 80
Issue 2

مصطلحات موضوعية: STD NMR spectroscopy, macrolide antibiotics, albumin, epitope mapping, albumine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a7e58d2ccc3267cfd4ff6568a65ca944
https://www.bib.irb.hr/299030

المؤلفون: Hollinger, Martin

المساهمون: Meyer, Bernd (Prof. Dr.)

مصطلحات موضوعية: Sättigungs-Transfer-Differenz (STD)-NMR Spektroskopie, Oberflächenplasmonenresonanz, Saturation-Transfer-Difference (STD) - NMR spectroscopy, plasmon surface resonance, 540 Chemie, 35.52 Präparative Organische Chemie, Arzneimitteldesign, Geflügelpestvirus, Molekulardesign, Neuraminsäurederivate, ddc:540

Relation: http://nbn-resolving.de/urn:nbn:de:gbv:18-42805; https://ediss.sub.uni-hamburg.de/handle/ediss/2719

الاتاحة: http://nbn-resolving.de/urn:nbn:de:gbv:18-42805
https://ediss.sub.uni-hamburg.de/handle/ediss/2719

المؤلفون: Ministerio de Asuntos Económicos y Transformación Digital (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), De Paz, J.L. [0000-0002-8555-2271], Nieto, Pedro M. [0000-0002-4074-9011], García-Jiménez, María José, Torres-Rico, Myriam, Paz, José L. de, Nieto, Pedro M.

مصطلحات الفهرس: Carbohydrate–protein interaction, Pleiotrophin, Chondroitin sulfate, GAG synthesis, Transient NMR methods, STD-NMR spectroscopy, artículo

URL: http://hdl.handle.net/10261/265253
https://doi.org/10.3390/ijms23063026
Publisher's version
https://doi.org/10.3390/ijms23063026
Sí
info:eu-repo/grantAgreement/MINECO-MCIN/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017 -2020/PGC2018-099497-B-100
info:eu-repo/grantAgreement/MINECO//CTQ2015-70134-P/ES/INTESIS DE GLICOSAMINOGLICANOS Y GLICOMIMETICOS, ESTRUCTURA EN DISOLUCION Y RECONOCIMIENTO MOLECULAR. IMPLICACIONES EN QUIMICA BIOLOGICA DE CARBOHIDRATOS