المؤلفون: COMPASS Consortium, INVENT Consortium, Estonian Biobank, PRECISEQ Consortium, FinnGen Consortium, MEGASTROKE Consortium, SIREN Consortium, Biobank Japan, CHARGE Consortium, GIGASTROKE Consortium, Regeneron Genetics Ctr, ODYSSEY Study, SICFAIL Study, Generacion Study, SMART Study, Helsinki Stroke Project, EPIC, Mishra, Aniket, Malik, Rainer, Hachiya, Tsuyoshi, Tomppo, Liisa, Havulinna, Aki S., Puurunen, Marja K., Weir, David, Putaala, Jukka, Sibolt, Gerli, Perola, Markus, Jousilahti, Pekka, Sarin, Antti-Pekka, Martinez-Majander, Nicolas, Zhou, Wei, Curtze, Sami, Tiainen, Marjaana, Kinnunen, Janne, Strbian, Daniel

المساهمون: HUS Neurocenter, Neurologian yksikkö, Clinicum, Department of Neurosciences, Helsinki University Hospital Area, University of Helsinki, Institute for Molecular Medicine Finland

مصطلحات موضوعية: GENOME-WIDE ASSOCIATION, MENDELIAN RANDOMIZATION, POLYGENIC RISK, HERITABILITY, STATISTICS, EXPRESSION, BRAIN, ATLAS, REGULARIZATION, METAANALYSIS, Neurosciences

وصف الملف: application/pdf

Relation: Detailed acknowledgements are provided in the Supplementary Information. We thank the participants and staff of contributing studies. We also thank Michele M. Sale, who passed away in 2018, for her important contributions to some of the studies included in this manuscript, as principal investigator of one of the grants that funded "The Sea Islands Genetics Network (SIGNET)" (R01 DK084350). She contributed specifically to SIGNET-REGARDS from the REasons for Geographic And Racial Differences in Stroke (REGARDS, U01 NS041588) and served as a key contributor to SiGN, COMPASS and METASTROKE.; COMPASS Consortium , INVENT Consortium , Estonian Biobank , PRECISEQ Consortium , FinnGen Consortium , MEGASTROKE Consortium , SIREN Consortium , Biobank Japan , CHARGE Consortium , GIGASTROKE Consortium , Regeneron Genetics Ctr , ODYSSEY Study , SICFAIL Study , Generacion Study , SMART Study , Helsinki Stroke Project , EPIC , Mishra , A , Malik , R , Hachiya , T , Tomppo , L , Havulinna , A S , Puurunen , M K , Weir , D , Putaala , J , Sibolt , G , Perola , M , Jousilahti , P , Sarin , A-P , Martinez-Majander , N , Zhou , W , Curtze , S , Curtze , S , Tiainen , M , Kinnunen , J & Strbian , D 2022 , ' Stroke genetics informs drug discovery and risk prediction across ancestries ' , Nature , vol. 611 , no. 7934 , pp. 115–123 . https://doi.org/10.1038/s41586-022-05165-3; ORCID: /0000-0003-1545-8500/work/128517922; http://hdl.handle.net/10138/353741; 77ac6188-7405-4f46-8dda-64ef16b3551c; 000862209300001

الاتاحة: http://hdl.handle.net/10138/353741