المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/journal_contribution/Characterisation_of_Nsp3_/14996504

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.s001

المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/journal_contribution/Characterization_of_inhibitors_/14996507

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.s002

المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/journal_contribution/Details_of_reagents_/14996516

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.s005

المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/journal_contribution/Design_of_PLpro_S1_-mutant_and_identified_inhibitory_nanobody_sequences_/14996510

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.s003

المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/journal_contribution/List_of_cDNA_constructs_/14996513

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.s004

المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/figure/Nsp3_sup_core_sup_is_a_more_active_protease_compared_to_PLpro_/14996519

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.g001

المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/figure/Development_of_nanobodies_that_inhibit_Nsp3_sup_core_sup_/14996528

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.g004

المؤلفون: Lee A. Armstrong (11146577), Sven M. Lange (11146580), Virginia Dee Cesare (11146583), Stephen P. Matthews (11146586), Raja Sekhar Nirujogi (841149), Isobel Cole (11146589), Anthony Hope (8841605), Fraser Cunningham (2069398), Rachel Toth (141271), Rukmini Mukherjee (3190851), Denisa Bojkova (8068613), Franz Gruber (4223701), David Gray (184988), Paul G. Wyatt (473658), Jindrich Cinatl (23848), Ivan Dikic (24996), Paul Davies (264924), Yogesh Kulathu (1293333)

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Evolutionary Biology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, host cell proteins, block PLpro activity, MALDI-TOF, 16 non-structural proteins, length Nsp 3, substrate binding site, K 48-linked polyubiquitin, SARS-CoV -2 infection assays, papain-like protease domain, ISG, Nsp 3 biology, Nsp 3, IC

Relation: https://figshare.com/articles/figure/Identification_and_characterization_of_PLpro_inhibitors_/14996525

الاتاحة: https://doi.org/10.1371/journal.pone.0253364.g003