المؤلفون: Omur Guven, Belgin Sever, Faika Başoğlu-Ünal, Abdulilah Ece, Hiroshi Tateishi, Ryoko Koga, Mohamed O. Radwan, Nefise Demir, Mustafa Can, Mutlu Dilsiz Aytemir, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita, Halilibrahim Ciftci, Hasan DeMirci

المصدر: Pharmaceuticals, Vol 16, Iss 11, p 1608 (2023)

مصطلحات موضوعية: TRAF6, zinc finger, RING domain, cancer, X-ray crystallography, structural biology, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/16/11/1608; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/1202296dce524954b7f465f6ba2024b8

المؤلفون: Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Kensaku Anraku, Kazuaki Monde, Çağdaş Dağ, Ebru Destan, Busra Yuksel, Esra Ayan, Gunseli Yildirim, Merve Yigin, F. Betul Ertem, Alaleh Shafiei, Omur Guven, Sabri O. Besler, Raymond G. Sierra, Chun Hong Yoon, Zhen Su, Mengling Liang, Burcin Acar, Turkan Haliloglu, Masami Otsuka, Fumiaki Yumoto, Mikako Fujita, Toshiya Senda, Hasan DeMirci

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/77d919cd60ce407e9fad3b1b4378ff45

المؤلفون: Halilibrahim Ciftci, Hiroshi Tateishi, Jun-ichiro Inoue, Kana Iwamaru, Kazuo Umezawa, Masami Otsuka, Mikako Fujita, Mohamed O. Radwan, Nanami Baba, Riko Nakagawa, Ryoko Koga, Takuma Chinen, Tsugumasa Toma, Yuna Tominaga

المصدر: Chemical and Pharmaceutical Bulletin. 2022, 70(7):477

المؤلفون: Hiroshi Tateishi, Kazuaki Monde, Kensaku Anraku, Ryoko Koga, Yuya Hayashi, Halil Ibrahim Ciftci, Hasan DeMirci, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Masami Otsuka, Mikako Fujita

المصدر: Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/155939fcd0ff43f9a3efc384ff447645

المؤلفون: Wataru Shida, Hiroshi Tateishi, Yurika Tahara, Mikako Fujita, Doaa Husham Majeed Alsaadi, Masato Watanabe, Ryoko Koga, Mohamed O. Radwan, Halil I. Ciftci, Sevgi Gezici, Yuki Kurauchi, Hiroshi Katsuki, Masami Otsuka, Koji Sugimura, Mikiyo Wada, Nazim Sekeroglu, Takashi Watanabe

المصدر: Molecules; Volume 24; Issue 21; Pages: 3850

مصطلحات موضوعية: Caucasian beech, beech, twig, Turkey, anti-leukemic activity

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Natural Products Chemistry; https://dx.doi.org/10.3390/molecules24213850

الاتاحة: https://doi.org/10.3390/molecules24213850

المؤلفون: Mohamed O. Radwan, Halil I. Ciftci, Taha F. S. Ali, Doha E. Ellakwa, Ryoko Koga, Hiroshi Tateishi, Akiko Nakata, Akihiro Ito, Minoru Yoshida, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka

المصدر: Molecules; Volume 24; Issue 18; Pages: 3295

مصطلحات موضوعية: STLC, SIRT2, anticancer, molecular docking, solubility

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Natural Products Chemistry; https://dx.doi.org/10.3390/molecules24183295

الاتاحة: https://doi.org/10.3390/molecules24183295

المؤلفون: Halil I Ciftci, Raymond G Sierra, Chun Hong Yoon, Zhen Su, Hiroshi Tateishi, Ryoko Koga, Koiwai Kotaro, Fumiaki Yumoto, Toshiya Senda, Mengling Liang, Soichi Wakatsuki, Masami Otsuka, Mikako Fujita, Hasan DeMirci

المصدر: International Journal of Molecular Sciences; Volume 20; Issue 7; Pages: 1675

مصطلحات موضوعية: Serial Femtosecond X-ray crystallography, human immunodeficiency virus, matrix protein, inositol hexaphosphate, ambient temperature

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biophysics; https://dx.doi.org/10.3390/ijms20071675

الاتاحة: https://doi.org/10.3390/ijms20071675

المؤلفون: Omur Guven, Halilibrahim Ciftci, Hiroshi Tateishi, Ryoko Koga, Mohamed O. Radwan, Belgin Sever, Jun-ichiro Inoue, Masami Otsuka, Mikako Fujita, Hasan DeMirci

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::65602250a37ce7643de745b08c64a81c
https://doi.org/10.1101/2023.02.25.529911

المؤلفون: Muhammed Karabacak, Mehlika Dilek Altıntop, Halil İbrahim Çiftçi, Ryoko Koga, Masami Otsuka, Mikako Fujita, Ahmet Özdemir

المصدر: Molecules, Vol 20, Iss 10, Pp 19066-19084 (2015)

مصطلحات موضوعية: pyrazoline, oxadiazole, anticancer activity, apoptosis, DNA cleavage, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/20/10/19066; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/912b566621df4952b782502d1cbc74da

المؤلفون: Mehlika Altıntop, Halil Ciftci, Mohamed Radwan, Belgin Sever, Zafer Kaplancıklı, Taha Ali, Ryoko Koga, Mikako Fujita, Masami Otsuka, Ahmet Özdemir

المصدر: Molecules; Volume 23; Issue 1; Pages: 59

مصطلحات موضوعية: thiadiazole, thiazole, benzothiazole, Bcr-Abl, kinase inhibitor, leukemia

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules23010059

الاتاحة: https://doi.org/10.3390/molecules23010059

المؤلفون: Tsugumasa Toma, Junpei Yamashita, Masahiro Kamo, Ryoko Koga, Yoshinari Okamoto, Hiroshi Tateishi, Masami Otsuka, MIKAKO FUJITA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::901817cd43c697b2b25f4d7cc96c9837
https://doi.org/10.21203/rs.3.rs-1400405/v1

المؤلفون: Mohamed O. Radwan, Tsugumasa Toma, Yuiichi Arakaki, Masahiro Kamo, Naoya Inoue, Ryoko Koga, Masami Otsuka, Hiroshi Tateishi, Mikako Fujita

المصدر: Bioorganic & Medicinal Chemistry. 86:117294

مصطلحات موضوعية: Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aba65821e0a12cc44f7f8717fb203f9
https://doi.org/10.1016/j.bmc.2023.117294

المؤلفون: Halil Ibrahim Ciftci, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita, Mohamed O. Radwan, Mustafa Can, Ryoko Koga, Safiye Emirdag Ozturk, Taha F. S. Ali, Zeynep Ocak

المصدر: Biological and Pharmaceutical Bulletin. 2018, 41(4):570

المؤلفون: Shusuke Kawakubo, Yasuhiro Tomitaka, Kenta Tomimura, Ryoko Koga, Hiroki Matsuoka, Seiji Uematsu, Kazuo Yamashita, Simon Y W Ho, Kazusato Ohshima

المصدر: Virus evolution. 8(2)

مصطلحات موضوعية: Virology, Microbiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f507eb7bed9b490fde7fcaa3ebc5b602
https://pubmed.ncbi.nlm.nih.gov/35903148

المؤلفون: Kanako Kawashima, Mayuko Hirota‐Tsukimachi, Tsugumasa Toma, Ryoko Koga, Kana Iwamaru, Yosuke Kanemaru, Misato Yanae, Ami Ahagon, Yurine Nakamura, Kensaku Anraku, Hiroshi Tateishi, Jin Gohda, Jun‐ichiro Inoue, Masami Otsuka, Mikako Fujita

المصدر: Chemical biologydrug designREFERENCES. 99(4)

مصطلحات موضوعية: Pharmacology, Membrane Glycoproteins, Receptor Activator of Nuclear Factor-kappa B, Chimera, Drug Discovery, Organic Chemistry, RANK Ligand, NF-kappa B, Molecular Medicine, Osteoclasts, Biochemistry, Glutathione Transferase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d565023e6e2145755af3c42afc3c70bc
https://pubmed.ncbi.nlm.nih.gov/34882966

المؤلفون: Mohamed O. Radwan, Jun-ichiro Inoue, Mikako Fujita, Hiroshi Tateishi, Tomohiko Ejima, Ryoko Koga, Masami Otsuka, Yosuke Kanemaru, Yoshinari Okamoto, Tomohiro Hida

المصدر: Bioorganic & Medicinal Chemistry Letters. 29:2162-2167

مصطلحات موضوعية: Clinical Biochemistry, Pharmaceutical Science, Oxidative phosphorylation, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Drug Discovery, Humans, Cytotoxicity, Molecular Biology, TNF Receptor-Associated Factor 6, chemistry.chemical_classification, Zinc finger, Molecular Structure, 010405 organic chemistry, Organic Chemistry, Dithiol, Zinc Fingers, NF-κB, Prodrug, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Molecular Medicine, Tumor necrosis factor alpha

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fb4c7defd5d5b51e46c227b25c9fa4
https://doi.org/10.1016/j.bmcl.2019.06.050

المؤلفون: Halil I. Ciftci, Akihiro Ito, Ryoko Koga, Mikako Fujita, Akiko Nakata, Yoshio Okiyama, Taha F.S. Ali, Takeo Ohsugi, Minoru Yoshida, Masami Otsuka, Teruki Honma, Mohamed O. Radwan

المصدر: Bioorganic & Medicinal Chemistry. 27:1767-1775

مصطلحات موضوعية: Cell Survival, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, SIRT2, 01 natural sciences, Biochemistry, Bleomycin, Structure-Activity Relationship, chemistry.chemical_compound, Sirtuin 2, Catalytic Domain, Drug Discovery, Humans, Structure–activity relationship, Moiety, Histidine, Binding site, Molecular Biology, IC50, Binding Sites, Nicotinamide, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, In vitro, 0104 chemical sciences, Histone Deacetylase Inhibitors, Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Sirtuin, MCF-7 Cells, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9220b55d3344a28cd5acf9d0160105eb
https://doi.org/10.1016/j.bmc.2019.03.003

المؤلفون: Zhen Su, Halil I. Ciftci, Busra Yuksel, Masami Otsuka, Kensaku Anraku, Mikako Fujita, Kotaro Koiwai, Chun Hong Yoon, Çağdaş Dağ, Alaleh Shafiei, Mengling Liang, Gunseli Yildirim, Kazuaki Monde, Toshiya Senda, Hasan DeMirci, Burcin Acar, Hiroshi Tateishi, Ryoko Koga, Raymond G. Sierra, Omur Guven, Fumiaki Yumoto, F. Betul Ertem, Turkan Haliloglu, Merve Yigin, Ebru Destan, Esra Ayan, Sabri O. Besler

المساهمون: Demirci, Hasan (ORCID 0000-0002-9135-5397 & YÖK ID 307350), Dağ, Çağdaş, Shafiei, Alaleh, Güven, Ömür, Besler, Sabri Özkan, Ertem, Fatma Betül, Çiftçi, Halilibrahim, Tateishi, Hiroshi, Koiwai, Kotaro, Koga, Ryoko, Anraku, Kensaku, Monde, Kazuaki, Destan, Ebru, Yüksel, Büşra, Ayan, Esra, Yıldırım, Günseli, Yığın, Merve, Sierra, Raymond G., Yoon, Chun Hong, Su, Zhen, Liang, Mengling, Acar, Burçin, Haliloğlu, Türkan, Otsuka, Masami, Yumoto, Fumiaki, Fujita, Mikako, Senda, Toshiya, Koç Üniversitesi İş Bankası Enfeksiyon Hastalıkları Uygulama ve Araştırma Merkezi (EHAM) / Koç University İşbank Center for Infectious Diseases (KU-IS CID), College of Sciences, Graduate School of Sciences and Engineering, Department of Molecular Biology and Genetics

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports

مصطلحات موضوعية: Models, Molecular, Cyclitol, Protein Conformation, Science, Association (object-oriented programming), Human immunodeficiency virus (HIV), HIV Infections, Crystal structure, Crystallography, X-Ray, medicine.disease_cause, Article, World health, chemistry.chemical_compound, Protein Domains, medicine, Molecule, Humans, Protein Precursors, Binding site, X-ray crystallography, Budding, Multidisciplinary, Binding Sites, Viral matrix protein, Chemistry, Virus Assembly, Cell Membrane, Binding sites, Cell membrane, HIV infections, HIV-1, Models molecular, Phosphoric monoester hydrolases, Protein conformation, Protein domains, Protein precursors, Virus assembly, Phosphoric Monoester Hydrolases, Multidisciplinary sciences, Science and technology, Membrane, Virion assembly, Biophysics, Medicine, Structural biology

وصف الملف: pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ba8bb3719fb61500020f51b8babec4
https://doi.org/10.1101/2021.02.21.432153

المؤلفون: Mikako Fujita, Hiroshi Tateishi, Kazunori Shimagaki, Ami Ahagon, Yoshihiro Yamaguchi, Ryoko Koga, Masami Otsuka, Haruna Fujino

المصدر: The Journal of general virology. 101(9)

مصطلحات موضوعية: 0301 basic medicine, Proteasome Endopeptidase Complex, Zinc binding, Proline, Mutant, Amino Acid Motifs, Human immunodeficiency virus (HIV), Biology, medicine.disease_cause, 03 medical and health sciences, Virology, Homologous chromosome, medicine, Humans, Point Mutation, Viral Regulatory and Accessory Proteins, Proteasome degradation, Escherichia coli, Binding Sites, 030102 biochemistry & molecular biology, Protein Stability, vpr Gene Products, Human Immunodeficiency Virus, Cell biology, Zinc, 030104 developmental biology, HEK293 Cells, Viral replication, HIV-2, Proteolysis, Mutant Proteins, Peptides, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c132a6cf388f0875e04e7df1d12a72d4
https://pubmed.ncbi.nlm.nih.gov/32553018

المؤلفون: Kimihiko Orito, Kei Noguchi, Naomi Taira, Tanima Biswas, Ryoko Koga, Junko Miyoshi, Masami Otsuka, Yoshinari Okamoto, Mikako Fujita, Tetsuya Negoto, Motohiro Morioka, Taha F.S. Ali

المصدر: European Journal of Medicinal Chemistry. 163:207-214

مصطلحات موضوعية: Carnosine, Pharmacology, Gerbil, PC12 Cells, 01 natural sciences, Neuroprotection, 03 medical and health sciences, chemistry.chemical_compound, Lipid oxidation, Drug Discovery, Animals, HSP70 Heat-Shock Proteins, CA1 Region, Hippocampal, 030304 developmental biology, Neurons, chemistry.chemical_classification, Aldehydes, 0303 health sciences, Reactive oxygen species, Cell Death, Lipid peroxide, 010405 organic chemistry, Organic Chemistry, General Medicine, Free radical scavenger, Rats, 0104 chemical sciences, Hsp70, Hydrazines, Neuroprotective Agents, chemistry, Ischemic Attack, Transient, Reperfusion Injury, Gerbillinae

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7c5bba18b886efb9f30d9502f58200
https://doi.org/10.1016/j.ejmech.2018.11.060