المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/journal_contribution/Key_i_glp-1_i_alleles_used_in_this_study_/16673287

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s008

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/journal_contribution/Phenotypic_analysis_of_the_effect_of_ER_stress_induced_by_DTT_treatment_on_suppression_of_Notch-dependent_tumorous_phenotypes_/16673293

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s010

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/journal_contribution/Phenotypic_analysis_of_the_effect_of_loss_of_i_cup-2_i_on_expression_of_the_Glp_phenotype_/16673290

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s009

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/journal_contribution/Phenotypic_analysis_of_the_effect_of_ER_stress_induced_by_DTT_treatment_on_suppression_of_a_i_gld-2_gld-1_i_Notch-independent_tumours_/16673296

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s011

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/journal_contribution/List_of_strains_used_/16673299

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s012

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/_-REC-8_and_-HIM-3_immunostaining_of_gonads_of_the_indicated_genotypes_/16673272

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s003

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Raw_unscaled_average_SYGL-1_intensity_measurements_of_individual_experiments_to_compare_SYGL-1_intensity_in_i_glp-1_ar202_i_genetic_backgrounds_/16673275

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s004

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/A_simplified_schematic_of_the_genetic_pathway_controlling_the_proliferation_vs_differentiation_balance_in_the_i_C_i_i_elegans_i_germline_and_the_consequence_of_disruption_of_key_players_in_the_pathway_on_the_phenotype_/16673266

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s001

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Raw_average_CUP-2_intensity_measurements_to_compare_CUP-2_levels_in_WT_vs_i_puf-8_q725_i_genetic_backgrounds_at_25_C_/16673269

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s002

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Effect_of_DTT_treatment_on_weak_Notch-dependent_tumours_and_Notch-independent_tumours_/16673278

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s005

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Raw_unscaled_average_SYGL-1_intensity_measurements_comparing_i_xbp-1_i_RNAi_treated_RNAi_germlines_against_empty_vector_control_RNAi_treated_germlines_of_i_cup-2_tm2838_sygl-1_am307_glp-1_ar202_i_/16673284

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s007

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Raw_unscaled_average_SYGL-1_intensity_measurements_of_individual_experiments_to_compare_SYGL-1_intensity_in_wildtype_and_i_glp-1_ar202_i_genetic_backgrounds_with_induction_of_ER_stress_by_DTT_treatment_/16673281

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.s006

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Derlin_mutants_have_smaller_proliferative_zone_sizes_/16673305

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.g002

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Loss_of_i_cup-2_i_decreases_SYGL-1_protein_levels_in_i_glp-1_ar202_i_germlines_/16673311

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.g004

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Chemical_induction_of_ER_stress_also_suppresses_Notch-dependent_tumours_and_suppression_of_tumours_by_loss_of_i_cup-2_i_activity_requires_i_xbp-1_i_a_key_player_in_the_Unfolded_Protein_Response_/16673320

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.g007

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Retrograde_transport_may_contribute_to_i_cup-2_i_activity_and_i_cup-2_i_is_required_mainly_within_the_germline_to_promote_germ_cell_proliferation_/16673317

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.g006

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/CUP-2_is_expressed_in_the_proliferative_zone_of_the_germline_and_co-localizes_with_SP12_an_ER_marker_/16673314

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.g005

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/figure/Chemical_induction_of_ER_stress_by_DTT_reduces_the_spread_of_SYGL-1_a_readout_for_GLP-1_Notch_signalling_in_i_glp-1_ar202_i_germlines_/16673323

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.g008

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/dataset/Loss_of_Derlin_activity_supresses_i_glp-1_gf_i_overproliferation_/16673326

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.t001

المؤلفون: Ramya Singh (11473498), Ryan B. Smit (11473501), Xin Wang (91924), Chris Wang (9188870), Hilary Racher (11473504), Dave Hansen (5411927)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Developmental Biology, Cancer, unfolded protein response, stem cell pools, primary signal controlling, many human diseases, erad ), suppresses, div >< p, derlin family proteins, caenorhabditis elegans <, notch signaling levels, derlin mutants may, proliferation phenotype associated, function mutations activate, proliferation suppression due, elegans <, notch signaling, proliferation suppression, c <, term functioning, including cancers, germ line, functioning properly

Relation: https://figshare.com/articles/dataset/Loss_of_Derlin_activity_suppress_i_glp-1_gf_i_overproliferation_in_the_proliferative_zone_/16673329

الاتاحة: https://doi.org/10.1371/journal.pgen.1009687.t002