نتائج البحث - "Ruza, Reinis R."

المساهمون: Alzheimer's Drug Discovery Foundation, Francis Crick Institute, Wellcome Trust, Cancer Research UK, UK Medical Research Council, Alzheimer's Research UK

المصدر: Journal of Medicinal Chemistry ; volume 65, issue 10, page 7212-7230 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.2c00162
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00162

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5

Academic Journal

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

المصدر: Nature Structural & Molecular Biology ; volume 27, issue 9, page 846-854 ; ISSN 1545-9993 1545-9985

الاتاحة: http://dx.doi.org/10.1038/s41594-020-0469-6
http://www.nature.com/articles/s41594-020-0469-6.pdf
http://www.nature.com/articles/s41594-020-0469-6

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6

Academic Journal

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

المؤلفون: Zhou, Daming, Duyvesteyn, Helen M. E., Chen, Cheng-Pin, Huang, Chung-Guei, Chen, Ting-Hua, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Ma, Che, Huo, Jiandong, Carrique, Loic, Malinauskas, Tomas, Ruza, Reinis R., Shah, Pranav N. M., Tan, Tiong Kit, Rijal, Pramila, Donat, Robert F., Godwin, Kerry, Buttigieg, Karen R., Tree, Julia A., Radecke, Julika, Paterson, Neil G., Supasa, Piyada, Mongkolsapaya, Juthathip, Screaton, Gavin R., Carroll, Miles W., Gilbert-Jaramillo, Javier, Knight, Michael L., James, William, Owens, Raymond J., Naismith, James H., Townsend, Alain R., Fry, Elizabeth E., Zhao, Yuguang, Ren, Jingshan, Stuart, David I., Huang, Kuan-Ying A.

المصدر: Nature Structural & Molecular Biology ; volume 27, issue 10, page 950-958 ; ISSN 1545-9993 1545-9985

الاتاحة: http://dx.doi.org/10.1038/s41594-020-0480-y
http://www.nature.com/articles/s41594-020-0480-y.pdf
http://www.nature.com/articles/s41594-020-0480-y

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7

Academic Journal

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

المساهمون: CAMS, Wellcome Trust, Cancer Research UK, UK Medical Research Council, EPA Cephalosporin Fund, Rosalind Franklin Institute, Chinese Academy of Medical Sciences

المصدر: Cell Host & Microbe ; volume 28, issue 3, page 445-454.e6 ; ISSN 1931-3128

الاتاحة: http://dx.doi.org/10.1016/j.chom.2020.06.010
https://api.elsevier.com/content/article/PII:S1931312820303516?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1931312820303516?httpAccept=text/plain

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8

Academic Journal

Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen

المؤلفون: Atkinson, Benjamin N., Steadman, David, Zhao, Yuguang, Sipthorp, James, Vecchia, Luca, Ruza, Reinis R., Jeganathan, Fiona, Lines, Georgie, Frew, Sarah, Monaghan, Amy, Kjær, Svend, Bictash, Magda, Jones, E. Yvonne, Fish, Paul V.

المساهمون: Cancer Research UK, Wellcome Trust, Alzheimer’s Research UK, Francis Crick Institute, Medical Research Council

المصدر: MedChemComm ; volume 10, issue 8, page 1361-1369 ; ISSN 2040-2503 2040-2511

الاتاحة: http://dx.doi.org/10.1039/c9md00096h
http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00096H

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9

Academic Journal

Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Shut State

المؤلفون: Fourati, Zeineb, Ruza, Reinis R., Laverty, Duncan, Drege, Emmanuelle, Delarue-Cochin, Sandrine, Joseph, Delphine, Koehl, Patrice, Smart, Trevor, Delarue, Marc

المصدر: Biophysical Journal ; volume 112, issue 3, page 553a ; ISSN 0006-3495

الاتاحة: http://dx.doi.org/10.1016/j.bpj.2016.11.2984
https://api.elsevier.com/content/article/PII:S0006349516340140?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006349516340140?httpAccept=text/plain

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10

Academic Journal

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

المصدر: Nature Structural & Molecular Biology ; volume 28, issue 3, page 326-326 ; ISSN 1545-9993 1545-9985

الاتاحة: https://doi.org/10.1038/s41594-021-00566-w
http://www.nature.com/articles/s41594-021-00566-w.pdf
http://www.nature.com/articles/s41594-021-00566-w

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11

Academic Journal

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

المصدر: Nature Structural & Molecular Biology ; volume 27, issue 11, page 1094-1094 ; ISSN 1545-9993 1545-9985

الاتاحة: https://doi.org/10.1038/s41594-020-00527-9
https://www.nature.com/articles/s41594-020-00527-9.pdf
https://www.nature.com/articles/s41594-020-00527-9

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12

Academic Journal

The SARS-CoV-2 Spike Harbours a Lipid Binding Pocket Which Modulates Stability of the Prefusion Trimer

المؤلفون: Carrique, Loic, Duyvesteyn, Helen ME, Malinauskas, Tomas, Zhao, Yuguang, Ren, Jingshan, Zhou, Daming, Walter, Thomas S., Radecke, Julika, Huo, Jiandong, Ruza, Reinis R., Shah, Pranav NM, Fry, Elizabeth, Stuart, David I.

المصدر: SSRN Electronic Journal ; ISSN 1556-5068

الاتاحة: http://dx.doi.org/10.2139/ssrn.3656643

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13

Academic Journal

Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines as Inhibitors of Notum Carboxylesterase Activity

المساهمون: Research Councils UK, Francis Crick Institute, Alzheimer???s Research UK, Wellcome Trust, University College London, Eli Lilly and Company, Cancer Research UK

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 17, page 9464-9483 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.0c00660
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c00660

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14

Academic Journal

5-Phenyl-1,3,4-oxadiazol-2(3 H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit

المؤلفون: Mahy, William, Willis, Nicky J., Zhao, Yuguang, Woodward, Hannah L., Svensson, Fredrik, Sipthorp, James, Vecchia, Luca, Ruza, Reinis R., Hillier, James, Kjær, Svend, Frew, Sarah, Monaghan, Amy, Bictash, Magda, Salinas, Patricia C., Whiting, Paul, Vincent, Jean-Paul, Jones, E. Yvonne, Fish, Paul V.

المساهمون: Medical Research Council, Wellcome Trust, Cancer Research UK, Alzheimer's Research UK

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 21, page 12942-12956 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.0c01391
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01391

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15

Academic Journal

5‑Phenyl-1,3,4-oxadiazol-2(3H)‑ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit.

المؤلفون: Mahy, William, Willis, Nicky J., Zhao, Yuguang, Woodward, Hannah L., Svensson, Fredrik, Sipthorp, James, Vecchia, Luca, Ruza, Reinis R., Hillier, James, Kjær, Svend, Frew, Sarah, Monaghan, Amy, Bictash, Magda, Salinas, Patricia C., Whiting, Paul, Vincent, Jean-Paul, Jones, E. Yvonne, Fish, Paul V.

المصدر: Journal of Medicinal Chemistry; 11/12/2020, Vol. 63 Issue 21, p12942-12956, 15p

16

Electronic Resource

Structural Details of an Allosteric Mechanism for Bimodal Anesthetic Modulation of Pentameric Ligand-Gated Ion Channels

المؤلفون: Howard, Rebecca J., Fourati, Zaineb, Heusser, Stephanie A., Hui, Haidai, Ruza, Reinis R., Sauguet, Ludovic, Lindahl, Erik, Delarue, Marc

مصطلحات الفهرس: Biophysics, Biofysik, Article in journal, info:eu-repo/semantics/article, text

URL: http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-240181
Biophysical Journal, 0006-3495, 2018, 114:3, s. 204A-204A

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