نتائج البحث - "Ruppin, Eytan"

المساهمون: National Institutes of Health, Institute for Information and Communications Technology Promotion, National Cancer Institute, Samsung Science & Technology Foundation, Samsung, Sungkyunkwan University, Kwanjeong Educational Foundation, Ministry of Science, ICT and Future Planning

المصدر: Med ; volume 5, issue 1, page 73-89.e9 ; ISSN 2666-6340

الاتاحة: http://dx.doi.org/10.1016/j.medj.2023.12.009
https://api.elsevier.com/content/article/PII:S2666634023004075?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2666634023004075?httpAccept=text/plain

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11

Academic Journal

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

المؤلفون: Riva, Laura, Yuan, Shuofeng, Yin, Xin, Martin-Sancho, Laura, Matsunaga, Naoko, Pache, Lars, Burgstaller-Muehlbacher, Sebastian, De Jesus, Paul D, Teriete, Peter, Hull, Mitchell V, Chang, Max W, Chan, Jasper Fuk-Woo, Cao, Jianli, Poon, Vincent Kwok-Man, Herbert, Kristina M, Cheng, Kuoyuan, Nguyen, Tu-Trinh H, Rubanov, Andrey, Pu, Yuan, Nguyen, Courtney, Choi, Angela, Rathnasinghe, Raveen, Schotsaert, Michael, Miorin, Lisa, Dejosez, Marion, Zwaka, Thomas P, Sit, Ko-Yung, Martinez-Sobrido, Luis, Liu, Wen-Chun, White, Kris M, Chapman, Mackenzie E, Lendy, Emma K, Glynne, Richard J, Albrecht, Randy, Ruppin, Eytan, Mesecar, Andrew D, Johnson, Jeffrey R, Benner, Christopher, Sun, Ren, Schultz, Peter G, Su, Andrew I, García-Sastre, Adolfo, Chatterjee, Arnab K, Yuen, Kwok-Yung, Chanda, Sumit K

المصدر: Nature. 586(7827)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Infectious Diseases, Lung, Pneumonia & Influenza, Orphan Drug, Emerging Infectious Diseases, Coronaviruses Therapeutics and Interventions, Pneumonia, Coronaviruses, Rare Diseases, Stem Cell Research, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Adenosine Monophosphate, Alanine, Alveolar Epithelial Cells, Antiviral Agents, Betacoronavirus, COVID-19, Cell Line, Coronavirus Infections, Cysteine Proteinase Inhibitors, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Drug Repositioning, Drug Synergism, Gene Expression Regulation, Humans, Hydrazones, Induced Pluripotent Stem Cells, Models, Biological, Morpholines, Pandemics, Pneumonia, Viral, Pyrimidines, Reproducibility of Results, SARS-CoV-2, Small Molecule Libraries, Triazines, Virus Internalization, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6p88f41f
https://escholarship.org/content/qt6p88f41f/qt6p88f41f.pdf

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12

Academic Journal

Beyond Synthetic Lethality: Charting the Landscape of Pairwise Gene Expression States Associated with Survival in Cancer.

المؤلفون: Magen, Assaf, Das Sahu, Avinash, Lee, Joo, Sharmin, Mahfuza, Lugo, Alexander, Gutkind, J, Schäffer, Alejandro, Ruppin, Eytan, Hannenhalli, Sridhar

المصدر: Cell Reports. 28(4)

مصطلحات موضوعية: cancer stratification, data mining, drug response, gene interactions, patient survival analysis, synthetic lethality, Antineoplastic Agents, Carcinogenesis, Gene Expression Regulation, Neoplastic, Genes, Neoplasm, Humans, Neoplasms, Organ Specificity, Survival Analysis, Synthetic Lethal Mutations

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/04k7q4h0

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13

Academic Journal

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice.

المصدر: Nature communications. 10(1)

مصطلحات موضوعية: Intestines, Animals, Mice, Inbred C57BL, Mice, Knockout, Humans, Mice, Bacteria, Melanoma, Ubiquitin-Protein Ligases, Antimicrobial Cationic Peptides, Membrane Proteins, Cell Proliferation, Unfolded Protein Response, Gastrointestinal Microbiome, Inbred C57BL, Knockout

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6qt5b0dh

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14

Academic Journal

Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy.

المصدر: Molecular Systems Biology. 15(3)

مصطلحات موضوعية: drug combination, drug resistance, immunotherapy, synergy, Computational Biology, Drug Resistance, Neoplasm, Drug Synergism, Female, Gene Expression Profiling, Humans, Immunotherapy, Male, Melanoma, Molecular Targeted Therapy, Synthetic Lethal Mutations

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8m85w242
https://escholarship.org/content/qt8m85w242/qt8m85w242.pdf

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15

Academic Journal

A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK

المؤلفون: Feng, Xiaodong, Arang, Nadia, Rigiracciolo, Damiano Cosimo, Lee, Joo Sang, Yeerna, Huwate, Wang, Zhiyong, Lubrano, Simone, Kishore, Ayush, Pachter, Jonathan A, König, Gabriele M, Maggiolini, Marcello, Kostenis, Evi, Schlaepfer, David D, Tamayo, Pablo, Chen, Qianming, Ruppin, Eytan, Gutkind, J Silvio

المصدر: Cancer Cell. 35(3)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Genetics, Eye Disease and Disorders of Vision, Cancer, Rare Diseases, 2.1 Biological and endogenous factors, Animals, Cell Line, Tumor, Cell Proliferation, Computational Biology, Focal Adhesion Kinase 1, GTP-Binding Protein alpha Subunits, Gq-G11, Genes, Lethal, Hippo Signaling Pathway, Humans, Melanoma, Mice, Neoplasm Transplantation, Phosphorylation, Prognosis, Protein Serine-Threonine Kinases, Signal Transduction, Survival Analysis, Uveal Neoplasms, FAK, G protein, GNA11, GNAQ, Hippo, MOB1, PTK2, YAP, signal transduction, uveal melanoma, Protein-Serine-Threonine Kinases, Neurosciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/64b720sp
https://escholarship.org/content/qt64b720sp/qt64b720sp.pdf

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16

Academic Journal

Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection : test negative design study

المؤلفون: Israel, Ariel, Merzon, Eugene, Schäffer, Alejandro A, Shenhar, Yotam, Green, Ilan, Golan-Cohen, Avivit, Ruppin, Eytan, Magen, Eli, Vinker, Shlomo

المصدر: BMJ: British Medical Journal, 2021 Nov . 375, 1-7.

URL الوصول: https://www.jstor.org/stable/27354845

17

Academic Journal

The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure

المساهمون: Wu, Victoria H., Yung, Bryan S., Faraji, Farhoud, Saddawi-Konefka, Robert, Wang, Zhiyong, Wenzel, Alexander T., Song, Miranda J., Pagadala, Meghana S., Clubb, Lauren M., Chiou, Joshua, Sinha, Sanju, Matic, Marin, Raimondi, Francesco, Hoang, Thomas S., Berdeaux, Rebecca, Vignali, Dario A. A., Iglesias-Bartolome, Ramiro, Carter, Hannah, Ruppin, Eytan, Mesirov, Jill P., Gutkind, J. Silvio

مصطلحات موضوعية: Animal, CD8-Positive T-Lymphocyte, Immunotherapy, Mice, Transgenic, Neoplasm, Signal Transduction, Tumor Microenvironment, cytotoxic T lymphocyte antigen 4, G protein coupled receptor, Settore BIO/11 - Biologia Molecolare

Relation: info:eu-repo/semantics/altIdentifier/pmid/37308665; info:eu-repo/semantics/altIdentifier/wos/WOS:001004898600003; volume:24; issue:8; firstpage:1318; lastpage:1330; numberofpages:13; journal:NATURE IMMUNOLOGY; https://hdl.handle.net/11384/140822; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85163140581

الاتاحة: https://hdl.handle.net/11384/140822
https://doi.org/10.1038/s41590-023-01529-7

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