المؤلفون: Rouleau, Michèle, Villeneuve, Lyne, Allain, Eric P., McCabe-Leroux, Jules, Tremblay, Sophie, Nguyen Van Long, Flora, Uchil, Ashwini, Joly-Beauparlant, Charles, Droit, Arnaud, Guillemette, Chantal

المساهمون: Canadian Institutes of Health Research, Canada Research Chairs

المصدر: BMC Cancer ; volume 24, issue 1 ; ISSN 1471-2407

الاتاحة: http://dx.doi.org/10.1186/s12885-024-12143-7
https://link.springer.com/content/pdf/10.1186/s12885-024-12143-7.pdf
https://link.springer.com/article/10.1186/s12885-024-12143-7/fulltext.html

المؤلفون: Nguyen Van Long, Flora, Valcourt‐Gendron, Délya, Caron, Patrick, Rouleau, Michèle, Villeneuve, Lyne, Simonyan, David, Le, Trang, Sergerie, Roxanne, Laverdière, Isabelle, Vanura, Katrina, Guillemette, Chantal

المساهمون: Canada Foundation for Innovation

المصدر: Clinical and Translational Medicine ; volume 13, issue 12 ; ISSN 2001-1326 2001-1326

الاتاحة: http://dx.doi.org/10.1002/ctm2.1442
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ctm2.1442

المؤلفون: Fernández-Marcelo, Tamara, Frías, Cristina, Pascua, Irene, Juan Chocano, María Del Carmen De, Head, Jacqueline, Gómez, Ana, Hernando Trancho, Florentino, Jarabo Sarceda, José Ramón, Díaz-Rubio García, Eduardo, Torres García, Antonio José, Rouleau, Michèle, Benito De Las Heras, Manuel R., Iniesta, Pilar, Iniesta Serrano, María Pilar

مصطلحات الفهرس: 616-006.04, PARP3, Telomerase, Lung cancer, Tumour cell lines, Ciencias Biomédicas, 24 Ciencias de la Vida, journal article, VoR

URL: https://hdl.handle.net/20.500.14352/93262
https://jeccr.biomedcentral.com/articles/10.1186/1756-9966-33-19

المؤلفون: Rouleau, Michèle, Nguyen Van Long, Flora, Turcotte, Véronique, Caron, Patrick, Lacombe, Louis, Aprikian, Armen, Saad, Fred, Carmel, Michel, Chevalier, Simone, Lévesque, Eric, Guillemette, Chantal

المساهمون: Fonds de Recherche du Québec - Santé, Gouvernement du Canada | Canadian Institutes of Health Research, Canada Research Chairs, Canada Research Chair in Pharmacogenomics

المصدر: British Journal of Cancer ; volume 128, issue 2, page 285-296 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/s41416-022-02040-w
https://www.nature.com/articles/s41416-022-02040-w.pdf
https://www.nature.com/articles/s41416-022-02040-w

المؤلفون: Caron, Patrick, Nguyen Van Long, Flora, Rouleau, Michèle, Bujold, Emmanuel, Fortin, Paul, Mohammadi, Siamak, Lévesque, Éric, Breton, Sylvie, Guillemette, Chantal

المساهمون: Canada Research Chairs, Canadian Institutes of Health Research

المصدر: Journal of Chromatography A ; volume 1677, page 463296 ; ISSN 0021-9673

الاتاحة: http://dx.doi.org/10.1016/j.chroma.2022.463296
https://api.elsevier.com/content/article/PII:S0021967322004897?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021967322004897?httpAccept=text/plain

المؤلفون: Rouleau, Michèle.

Thesis Advisors: Tenniswood, M.

مصطلحات موضوعية: Biology, Animal Physiology.

وصف الملف: 160 p.

الاتاحة: http://hdl.handle.net/10393/5991

المؤلفون: Lévesque, Eric, Labriet, Adrien, Hovington, Hélène, Allain, Éric P., Melo-Garcia, Luciana, Rouleau, Michèle, Brisson, Hervé, Turcotte, Véronique, Caron, Patrick, Villeneuve, Lyne, Leclercq, Mickaël, Droit, Arnaud, Audet-Walsh, Etienne, Simonyan, David, Fradet, Yves, Lacombe, Louis, Guillemette, Chantal

المساهمون: Prostate Cancer Canada, Cancer Research Society, Fonds de Recherche du Québec-Société et Culture

المصدر: British Journal of Cancer ; volume 122, issue 7, page 1068-1076 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/s41416-020-0749-2
http://www.nature.com/articles/s41416-020-0749-2.pdf
http://www.nature.com/articles/s41416-020-0749-2

المؤلفون: Allain, Eric P., Rouleau, Michèle, Vanura, Katrina, Tremblay, Sophie, Vaillancourt, Joanie, Bat, Vincent, Caron, Patrick, Villeneuve, Lyne, Labriet, Adrien, Turcotte, Véronique, Le, Trang, Shehata, Medhat, Schnabl, Susanne, Demirtas, Dita, Hubmann, Rainer, Joly-Beauparlant, Charles, Droit, Arnaud, Jäger, Ulrich, Staber, Philipp B., Lévesque, Eric, Guillemette, Chantal

المساهمون: Gouvernement du Canada | Canadian Institutes of Health Research

المصدر: British Journal of Cancer ; volume 123, issue 2, page 240-251 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/s41416-020-0887-6
http://www.nature.com/articles/s41416-020-0887-6.pdf
http://www.nature.com/articles/s41416-020-0887-6

المؤلفون: Guillemette, Chantal, Rouleau, Michèle, Vanura, Katrina, Lévesque, Éric

المساهمون: Gouvernement du Canada | Canadian Institutes of Health Research

المصدر: British Journal of Cancer ; volume 123, issue 8, page 1347-1348 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/s41416-020-1006-4
http://www.nature.com/articles/s41416-020-1006-4.pdf
http://www.nature.com/articles/s41416-020-1006-4

المؤلفون: Allain, Eric P., Rouleau, Michèle, Lévesque, Eric, Guillemette, Chantal

المساهمون: Gouvernement du Canada | Canadian Institutes of Health Research

المصدر: British Journal of Cancer ; volume 122, issue 9, page 1277-1287 ; ISSN 0007-0920 1532-1827

الاتاحة: http://dx.doi.org/10.1038/s41416-019-0722-0
http://www.nature.com/articles/s41416-019-0722-0.pdf
http://www.nature.com/articles/s41416-019-0722-0

المؤلفون: Ferreira, Maria Tedim, Berger, Louise, Rouleau, Michèle, Poirier, Guy G.

المساهمون: canadian institutes of health research

المصدر: Journal of Histochemistry & Cytochemistry ; volume 68, issue 6, page 413-435 ; ISSN 0022-1554 1551-5044

الاتاحة: https://doi.org/10.1369/0022155420926022
https://journals.sagepub.com/doi/pdf/10.1369/0022155420926022
https://journals.sagepub.com/doi/full-xml/10.1369/0022155420926022

المؤلفون: Guillemette, Chantal, Vanura, Katrina, Le, Trang, Rouleau, Michèle, Allain, Eric P., Villeneuve, Lyne, Caron, Patrick, Turcotte, Véronique, Lévesque, Eric

مصطلحات موضوعية: UGT2B17, CLL, prostaglandins, glucuronidation, PGE2

جغرافية الموضوع: UMW:14557

وصف الملف: text/html

Relation: vignette : https://repositorium.meduniwien.ac.at/titlepage/urn/urn:nbn:at:at-ubmuw:3-39118/128; urn:nbn:at:at-ubmuw:3-39118; https://resolver.obvsg.at/urn:nbn:at:at-ubmuw:3-39118; local:99145986888303331; system:AC16185786

الاتاحة: https://doi.org/10.3389/fonc.2019.00606
https://repositorium.meduniwien.ac.at/doi/10.3389/fonc.2019.00606
https://resolver.obvsg.at/urn:nbn:at:at-ubmuw:3-39118

المؤلفون: Labriet, Adrien, Lévesque, Éric, Cecchin, Erika, De Mattia, Elena, Villeneuve, Lyne, Rouleau, Michèle, Jonker, Derek, Couture, Félix, Simonyan, David, Allain, Eric P., Buonadonna, Angela, D’Andrea, Mario, Toffoli, Giuseppe, Guillemette, Chantal

المساهمون: Gouvernement du Canada | Canadian Institutes of Health Research

المصدر: Scientific Reports ; volume 9, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-019-49477-3
https://www.nature.com/articles/s41598-019-49477-3.pdf
https://www.nature.com/articles/s41598-019-49477-3

المؤلفون: Guauque Olarte, Sandra Milena, Tourancheau, Alan, Rouleau, Michèle, Villeneuve, Lyne, Gilbert, Isabelle, Droit, Arneaud, Guillemette, Chantal

مصطلحات موضوعية: UGT, Transcriptome, Epigenetics, Pharmacogenomics

جغرافية الموضوع: 18(2)

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

Relation: https://www.nature.com/articles/tpj20175; https://corpus.ulaval.ca/jspui/handle/20.500.11794/13068; The Pharmacogenomics Journal; 1. Bellemare J, Rouleau M, Harvey M, Guillemette C. Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions. J Biol Chem 2010; 285: 3600- 3607.; 2. Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, et al. Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines. Pharmacogenomics J 2016.; 3. Menard V, Collin P, Margaillan G, Guillemette C. Modulation of the UGT2B7 enzyme activity by C-terminally truncated proteins derived from alternative splicing. Drug Metab Dispos 2013; 41: 2197-2205.; 4. Guillemette C, Levesque E, Rouleau M. Pharmacogenomics of human uridine diphospho-glucuronosyltransferases and clinical implications. Clin Pharmacol Ther 2014; 96: 324-339.; 5. Stingl JC, Bartels H, Viviani R, Lehmann ML, Brockmoller J. Relevance of UDPglucuronosyltransferase polymorphisms for drug dosing: A quantitative systematic review. Pharmacol Ther 2014; 141: 92-116.; 6. Meech R, Rogers A, Zhuang L, Lewis BC, Miners JO, Mackenzie PI. Identification of residues that confer sugar selectivity to UDP-glycosyltransferase 3A (UGT3A) enzymes. J Biol Chem 2012; 287: 24122-24130; 7. Meech R, Mubarokah N, Shivasami A, Rogers A, Nair PC, Hu DG, et al. A novel function for UDP glycosyltransferase 8: galactosidation of bile acids. Mol Pharmacol 2015; 87: 442-450.; 8. Tourancheau A, Margaillan G, Rouleau M, Gilbert I, Villeneuve L, Levesque E, et al. Unravelling the transcriptomic landscape of the major phase II UDPglucuronosyltransferase drug metabolizing pathway using targeted RNA sequencing. Pharmacogenomics J 2016; 16: 60-70.; 9. Langmead B, Salzberg SL. Fast gapped-read alignment with Bowtie 2. Nat Methods 2012; 9: 357-359.; 11. Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 2013; 14: R36.; 12. Goff L, Trapnell C, Kelley D. cummeRbund: Analysis, exploration, manipulation, and visualization of Cufflinks high-throughput sequencing data. R package version 282 2013.; 13. R Development Core Team, R.C. (2008). R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing, Vienna, Austria; URL: https://www.R-project.org.; 14. den Dunnen JT, Dalgleish R, Maglott DR, Hart RK, Greenblatt MS, McGowanJordan J, et al. HGVS Recommendations for the Description of Sequence Variants: 2016 Update. Hum Mutat 2016; 37: 564-569.; 15. MacKenzie PI, Rogers A, Elliot DJ, Chau N, Hulin JA, Miners JO, et al. The novel UDP glycosyltransferase 3A2: cloning, catalytic properties, and tissue distribution. Mol Pharmacol 2011; 79: 472-478.; 16. Mackenzie PI, Rogers A, Treloar J, Jorgensen BR, Miners JO, Meech R. Identification of UDP glycosyltransferase 3A1 as a UDP Nacetylglucosaminyltransferase. J Biol Chem 2008; 283: 36205-36210.; 17. McCarroll SA, Hadnott TN, Perry GH, Sabeti PC, Zody MC, Barrett JC, et al. Common deletion polymorphisms in the human genome. Nat Genet 2006; 38: 86- 92.; 18. Bellemare J, Rouleau M, Harvey M, Popa I, Pelletier G, Tetu B, et al. Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans. J Pathol 2011; 223: 425-435; 19. Court MH, Zhang X, Ding X, Yee KK, Hesse LM, Finel M. Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues. Xenobiotica 2012; 42: 266-277; 20. Margaillan G, Rouleau M, Fallon JK, Caron P, Villeneuve L, Turcotte V, et al. Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues. Drug Metab Dispos 2015; 43: 611-619.; 21. Margaillan G, Rouleau M, Klein K, Fallon JK, Caron P, Villeneuve L, et al. Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential. Drug Metab Dispos 2015; 43: 1331-1335.; 22. Ohno S, Nakajin S. Determination of mRNA expression of human UDPglucuronosyltransferases and application for localization in various human tissues by real-time reverse transcriptase-polymerase chain reaction. Drug Metab Dispos 2009; 37: 32-40.; 23. Hart T, Komori HK, LaMere S, Podshivalova K, Salomon DR. Finding the active genes in deep RNA-seq gene expression studies. BMC Genomics 2013; 14: 778.; 24. Menard V, Levesque E, Chen S, Eap O, Joy MS, Ekstrom L, et al. Expression of UGT2B7 is driven by two mutually exclusive promoters and alternative splicing in human tissues: changes from prenatal life to adulthood and in kidney cancer. Pharmacogenet Genomics 2013; 23: 684-696.; 25. Rouleau M, Roberge J, Bellemare J, Guillemette C. Dual roles for splice variants of the glucuronidation pathway as regulators of cellular metabolism. Mol Pharmacol 2014; 85: 29-36; 26. Rouleau M, Tourancheau A, Girard-Bock C, Villeneuve L, Vaucher J, Duperre AM, et al. Divergent Expression and Metabolic Functions of Human Glucuronosyltransferases through Alternative Splicing. Cell Rep 2016; 17: 114- 124; 27. Nagy E, Maquat LE. A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance. Trends Biochem Sci 1998; 23: 198-199.; 28. Bushey RT, Dluzen DF, Lazarus P. Importance of UDP-glucuronosyltransferases 2A2 and 2A3 in tobacco carcinogen metabolism. Drug Metab Dispos 2013; 41: 170-179.; 29. Bushey RT, Lazarus P. Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobaccorelated cancer susceptibility. J Pharmacol Exp Ther 2012; 343: 712-724.; 30. Audet-Delage Y, Rouleau M, Rouleau M, Roberge J, Miard S, Picard F, et al. Crosstalk between alternatively spliced UGT1A isoforms and colon cancer cell metabolism. Submitted 2016.; 31. Shkreta L, Bell B, Revil T, Venables JP, Prinos P, Elela SA, et al. CancerAssociated Perturbations in Alternative Pre-messenger RNA Splicing. Cancer Treat Res 2013; 158: 41-94.; 32. Levesque E, Menard V, Laverdiere I, Bellemare J, Barbier O, Girard H, et al. Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation. Pharmacogenet Genomics 2010; 20: 195- 210.; 33. Menard V, Eap O, Roberge J, Harvey M, Levesque E, Guillemette C. Transcriptional diversity at the UGT2B7 locus is dictated by extensive pre-mRNA splicing mechanisms that give rise to multiple mRNA splice variants. Pharmacogenet Genomics 2011; 21: 631-641.; https://hdl.handle.net/20.500.12494/15372; Alan Tourancheau, Michèle Rouleau, Sandra Guauque-Olarte, Lyne Villeneuve, Isabelle Gilbert, Arnaud Droit and Chantal Guillemette. Quantitative profiling of the UGT transcriptome in human drug-metabolizing tissues. Pharmacogenomics J. 2018 Apr;18(2):251-261. doi:10.1038/tpj.2017.5. Epub 2017 Apr 25. Recuperado de

الاتاحة: https://hdl.handle.net/20.500.12494/15372
https://doi.org/10.1038/tpj.2017.5

المؤلفون: Gagné, Jean-Philippe, Rouleau, Michèle, Poirier, Guy G.

المصدر: Science, 2012 May 01. 336(6082), 678-679.

URL الوصول: http://dx.doi.org/10.1126/science.1221870

المؤلفون: Rouleau, Michèle, Audet-Delage, Yannick, Desjardins, Sylvie, Rouleau, Mélanie, Girard-Bock, Camille, Guillemette, Chantal

المساهمون: Natural Sciences and Engineering Research Council of Canada

المصدر: Frontiers in Pharmacology ; volume 8 ; ISSN 1663-9812

الاتاحة: http://dx.doi.org/10.3389/fphar.2017.00023
http://journal.frontiersin.org/article/10.3389/fphar.2017.00023/full

المؤلفون: Strickfaden, Hilmar, McDonald, Darin, Kruhlak, Michael J., Haince, Jean-Francois, Th'ng, John P.H., Rouleau, Michele, Ishibashi, Toytaka, Corry, Gareth N., Ausio, Juan, Underhill, D. Alan, Poirier, Guy G., Hendzel, Michael J.

المساهمون: Canadian Institutes of Health Research

المصدر: Journal of Biological Chemistry ; volume 291, issue 4, page 1789-1802 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.m115.694992
https://api.elsevier.com/content/article/PII:S0021925820361147?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820361147?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M115.694992

المؤلفون: Rouleau, Michèle, Tourancheau, Alan, Girard-Bock, Camille, Villeneuve, Lyne, Vaucher, Jonathan, Duperré, Anne-Marie, Audet-Delage, Yannick, Gilbert, Isabelle, Popa, Ion, Droit, Arnaud, Guillemette, Chantal

المصدر: Cell Reports ; volume 17, issue 1, page 114-124 ; ISSN 2211-1247

الاتاحة: http://dx.doi.org/10.1016/j.celrep.2016.08.077
https://api.elsevier.com/content/article/PII:S2211124716311731?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2211124716311731?httpAccept=text/plain

المؤلفون: Wagner, Antoine¹ (AUTHOR), Rouleau, Michèle¹ (AUTHOR), Villeneuve, Lyne¹ (AUTHOR), Le, Trang² (AUTHOR), Peltier, Cheryl^3,4 (AUTHOR), Allain, Éric P.⁵ (AUTHOR), Beaudoin, Caroline¹ (AUTHOR), Tremblay, Sophie¹ (AUTHOR), Courtier, Fréderic¹ (AUTHOR), Nguyen Van Long, Flora¹ (AUTHOR), Laverdière, Isabelle¹ (AUTHOR), Lévesque, Éric⁶ (AUTHOR), Banerji, Versha^3,4 (AUTHOR), Vanura, Katrina² (AUTHOR), Guillemette, Chantal¹ (AUTHOR) chantal.guillemette@crchudequebec.ulaval.ca

المصدر: Cells (2073-4409). May2023, Vol. 12 Issue 9, p1295. 16p.

مصطلحات موضوعية: *B cell receptors, *BRUTON tyrosine kinase, *PROTEIN-tyrosine kinases, *CHRONIC lymphocytic leukemia, *ENZYMES, *FC receptors

المؤلفون: Rouleau, Michèle, Nguyen Van Long, Flora, Turcotte, Véronique, Caron, Patrick, Lacombe, Louis, Aprikian, Armen, Saad, Fred, Carmel, Michel, Chevalier, Simone, Lévesque, Eric, Guillemette, Chantal

المصدر: British Journal of Cancer; Jan2023, Vol. 128 Issue 2, p285-296, 12p