المؤلفون: Buckberry, S., Liu, X., Poppe, D., Tan, J.P., Sun, G., Chen, J., Nguyen, T.V., de Mendoza, A., Pflueger, J., Frazer, T., Vargas-Landín, D.B., Paynter, J.M., Smits, N., Liu, N., Ouyang, J.F., Rossello, F.J., Chy, H.S., Rackham, O.J.L., Laslett, A.L., Breen, J.

المصدر: http://dx.doi.org/10.1038/s41586-023-06424-7.

مصطلحات موضوعية: Epigenetic memory, Epigenomics, Reprogramming, Chromatin, Humans, DNA Transposable Elements, DNA Methylation, Epigenesis, Genetic, Induced Pluripotent Stem Cells, Cellular Reprogramming, Human Embryonic Stem Cells, DNA Demethylation

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1069830; http://purl.org/au-research/grants/nhmrc/1178460; http://purl.org/au-research/grants/arc/LE170100225; http://purl.org/au-research/grants/arc/FT180100674; http://purl.org/au-research/grants/nhmrc/1104560; http://purl.org/au-research/grants/nhmrc/1111206; http://purl.org/au-research/grants/arc/1111206; http://purl.org/au-research/grants/nhmrc/1173711; Nature, 2023; 620(7975):863-872; https://hdl.handle.net/2440/140035; Liu, X. [0000-0002-9487-9305]; Breen, J. [0000-0001-6184-0925]; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/140035
https://doi.org/10.1038/s41586-023-06424-7

المؤلفون: Chen, J., Neil, J.A., Tan, J.P., Rudraraju, R., Mohenska, M., Sun, Y.B.Y., Walters, E., Bediaga, N.G., Sun, G., Zhou, Y., Li, Y., Drew, D., Pymm, P., Tham, W.H., Rossello, F.J., Nie, G., Liu, X., Subbarao, K., Polo, J.M.

المصدر: http://dx.doi.org/10.1038/s41556-023-01182-0.

مصطلحات موضوعية: Trophoblasts, Placenta, Humans, Cell Differentiation, Pregnancy, Female, COVID-19, Angiotensin-Converting Enzyme 2, SARS-CoV-2

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/2004774; http://purl.org/au-research/grants/nhmrc/1177174; Nature Cell Biology, 2023; 25(8):1223-1234; https://hdl.handle.net/2440/139124; Walters, E. [0000-0002-4533-7884]; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/139124
https://doi.org/10.1038/s41556-023-01182-0

المؤلفون: Nefzger, C.M., Jardé, T., Srivastava, A., Schroeder, J., Rossello, F.J., Horvay, K., Prasko, M., Paynter, J.M., Chen, J., Weng, C.-F., Sun, Y.B.Y., Liu, X., Chan, E., Deshpande, N., Chen, X., Li, Y.J., Pflueger, J., Engel, R.M., Knaupp, A.S., Tsyganov, K.

المصدر: http://dx.doi.org/10.1038/s41536-022-00226-7.

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1061883; http://purl.org/au-research/grants/nhmrc/1188689; http://purl.org/au-research/grants/nhmrc/1146623; http://purl.org/au-research/grants/nhmrc/1129600; npj Regenerative Medicine, 2022; 7(1):31-1-31-8; https://hdl.handle.net/2440/135652; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/135652
https://doi.org/10.1038/s41536-022-00226-7

المؤلفون: Law, A.M.K., Chen, J., Colino-Sanguino, Y., Fuente, L.R.D.L., Fang, G., Grimes, S.M., Lu, H., Huang, R.J., Boyle, S.T., Venhuizen, J., Castillo, L., Tavakoli, J., Skhinas, J.N., Millar, E.K.A., Beretov, J., Rossello, F.J., Tipper, J.L., Ormandy, C.J., Samuel, M.S., Cox, T.R.

المصدر: http://dx.doi.org/10.1002/advs.202103332.

مصطلحات موضوعية: alginate, ex vivo drug screening, single-cell RNAseq, three dimensional culture, tissue microenvironment, whole-tissue organoids

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/GNT114519; http://purl.org/au-research/grants/nhmrc/GNT1184809; http://purl.org/au-research/grants/nhmrc/GNT2012941; http://purl.org/au-research/grants/nhmrc/GNT1158590; Advanced Science, 2022; 9(21):2103332-1-2103332-19; https://hdl.handle.net/2440/135378; Samuel, M.S. [0000-0001-7880-6379]; Martelotto, L. [0000-0002-9625-1183]

الاتاحة: https://hdl.handle.net/2440/135378
https://doi.org/10.1002/advs.202103332

المؤلفون: Zethoven, M., Martelotto, L., Pattison, A., Bowen, B., Balachander, S., Flynn, A., Rossello, F.J., Hogg, A., Miller, J.A., Frysak, Z., Grimmond, S., Fishbein, L., Tischler, A.S., Gill, A.J., Hicks, R.J., Dahia, P.L.M., Clifton-Bligh, R., Pacak, K., Tothill, R.W.

المصدر: http://dx.doi.org/10.1038/s41467-022-34011-3.

مصطلحات موضوعية: Humans, Paraganglioma, Pheochromocytoma, Adrenal Gland Neoplasms, Succinate Dehydrogenase, Tumor Microenvironment

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1108032; Nature Communications, 2022; 13(1):6262-6262; https://hdl.handle.net/2440/137150; Martelotto, L. [0000-0002-9625-1183]

الاتاحة: https://hdl.handle.net/2440/137150
https://doi.org/10.1038/s41467-022-34011-3

المؤلفون: Salmon, J.M., Todorovski, I., Stanley, K.L., Bruedigam, C., Kearney, C.J., Martelotto, L.G., Rossello, F.J., Semple, T., Mir Arnau, G., Zethoven, M., Bots, M., Bjelosevic, S., Cluse, L.A., Fraser, P.J., Litalien, V., Vidacs, E., McArthur, K., Matthews, A.Y., Gressier, E., de Weerd, N.A.

المصدر: http://dx.doi.org/10.1158/2159-8290.cd-20-1145.

مصطلحات موضوعية: Dendritic Cells, Humans, Histone Deacetylases, Cell Differentiation, Epigenesis, Genetic, Leukemia, Myeloid, Acute, Histone Deacetylase Inhibitors, Panobinostat

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/GNT1178339; http://purl.org/au-research/grants/nhmrc/1113577; http://purl.org/au-research/grants/nhmrc/1063008; http://purl.org/au-research/grants/nhmrc/GNT2011217; Cancer Discovery, 2022; 12(6):1560-1579; https://hdl.handle.net/2440/135425; Martelotto, L.G. [0000-0002-9625-1183]; Kile, B.T. [0000-0002-8836-8947]

الاتاحة: https://hdl.handle.net/2440/135425
https://doi.org/10.1158/2159-8290.CD-20-1145

المؤلفون: Hauswirth, G.M., Garside, V.C., Wong, L.S.F., Bildsoe, H., Manent, J., Chang, Y.-C., Nefzger, C.M., Firas, J., Chen, J., Rossello, F.J., Polo, J.M., McGlinn, E.

المصدر: http://dx.doi.org/10.1038/s41467-021-27335-z.

مصطلحات موضوعية: Spine, Tail, Animals, Mammals, Mice, Tretinoin, Homeodomain Proteins, Bone Morphogenetic Proteins, MicroRNAs, Body Patterning, Genes, Homeobox, Growth Differentiation Factors, Biological Evolution, Transcriptome

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1051792; http://purl.org/au-research/grants/arc/DP180102157; Nature Communications, 2022; 13(1):1-12; https://hdl.handle.net/2440/134236; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/134236
https://doi.org/10.1038/s41467-021-27335-z

المؤلفون: Grubman, A., Choo, X.Y., Chew, G., Ouyang, J.F., Sun, G., Croft, N.P., Rossello, F.J., Simmons, R., Buckberry, S., Landin, D.V., Pflueger, J., Vandekolk, T.H., Abay, Z., Zhou, Y., Liu, X., Chen, J., Larcombe, M., Haynes, J.M., McLean, C., Williams, S.

المصدر: http://dx.doi.org/10.1038/s41467-021-23111-1.

مصطلحات موضوعية: Amyloid plaque, Brain, Microglia, Animals, Humans, Mice, Alzheimer Disease, Disease Models, Animal, Phagocytosis, Gene Expression, Aged, 80 and over, Middle Aged, Female, Male, Hypoxia-Inducible Factor 1, alpha Subunit, Gene Regulatory Networks, Plaque, Amyloid, Transcriptome

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/GNT1097461; Nature Communications, 2021; 12(1):3015-1-3015-22; https://hdl.handle.net/2440/133831; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133831
https://doi.org/10.1038/s41467-021-23111-1

المؤلفون: Knaupp, A.S., Mohenska, M., Larcombe, M.R., Ford, E., Lim, S.M., Wong, K., Chen, J., Firas, J., Huang, C., Liu, X., Nguyen, T., Sun, Y.B.Y., Holmes, M.L., Tripathi, P., Pflueger, J., Rossello, F.J., Schröder, J., Davidson, K.C., Nefzger, C.M., Das, P.P.

المصدر: http://dx.doi.org/10.1016/j.stemcr.2020.11.005.

مصطلحات موضوعية: Epigenetics, Nanog, single-locus pull-down, pluripotency, transcriptional complex, RCOR2, iPSCs, reprogramming, TINC, Humans, Multiprotein Complexes, Genetic Loci, Co-Repressor Proteins, Human Embryonic Stem Cells, Nanog Homeobox Protein

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1178460; http://purl.org/au-research/grants/nhmrc/APP1092280; http://purl.org/au-research/grants/nhmrc/1069830; http://purl.org/au-research/grants/arc/CE140100008; http://purl.org/au-research/grants/nhmrc/1036587; http://purl.org/au-research/grants/arc/FT120100862; http://purl.org/au-research/grants/arc/FT180100674; Stem Cell Reports, 2020; 15(6):1246-1259; https://hdl.handle.net/2440/133443; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133443
https://doi.org/10.1016/j.stemcr.2020.11.005

المؤلفون: La, H.M., Mäkelä, J.A., Chan, A.L., Rossello, F.J., Nefzger, C.M., Legrand, J.M.D., De Seram, M., Polo, J.M., Hobbs, R.M.

المصدر: http://dx.doi.org/10.1038/s41467-018-04827-z.

مصطلحات موضوعية: Spermatogonia, Testis, Stem Cells, Animals, Mice, Transgenic, Integrases, Homeodomain Proteins, Trans-Activators, Luminescent Proteins, Gene Expression Profiling, Cell Differentiation, Gene Expression Regulation, Developmental, Cell Lineage, Founder Effect, Genes, Reporter, Male, Proto-Oncogene Proteins c-kit, Octamer Transcription Factor-3, Single-Cell Analysis, Promyelocytic Leukemia Zinc Finger Protein

وصف الملف: application/pdf

Relation: Nature Communications, 2018; 9(1):1-18; https://hdl.handle.net/2440/133490; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133490
https://doi.org/10.1038/s41467-018-04827-z

المؤلفون: O’Brien, C.M., Chy, H.S., Zhou, Q., Blumenfeld, S., Lambshead, J.W., Liu, X., Kie, J., Capaldo, B.D., Chung, T.L., Adams, T.E., Phan, T., Bentley, J.D., McKinstry, W.J., Oliva, K., McMurrick, P.J., Wang, Y.C., Rossello, F.J., Lindeman, G.J., Chen, D., Jarde, T.

المصدر: http://dx.doi.org/10.1002/stem.2558.

مصطلحات موضوعية: Hematopoietic Stem Cells, Pluripotent Stem Cells, Animals, Humans, Mice, Membrane Proteins, Antibodies, Monoclonal, Antigens, Surface, Flow Cytometry, Cell Culture Techniques, Cell Differentiation, Down-Regulation, Octamer Transcription Factor-3, Embryoid Bodies, Cell Self Renewal

وصف الملف: application/pdf

Relation: Stem Cells, 2017; 35(3):626-640; https://hdl.handle.net/2440/133641; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133641
https://doi.org/10.1002/stem.2558

المؤلفون: Nefzger, C.M., Rossello, F.J., Chen, J., Liu, X., Knaupp, A.S., Firas, J., Paynter, J.M., Pflueger, J., Buckberry, S., Lim, S.M., Williams, B., Alaei, S., Faye-Chauhan, K., Petretto, E., Nilsson, S.K., Lister, R., Ramialison, M., Powell, D.R., Rackham, O.J.L., Polo, J.M.

المصدر: http://dx.doi.org/10.1016/j.celrep.2017.11.029.

مصطلحات موضوعية: Neutrophils, Fibroblasts, Keratinocytes, Animals, Humans, Flow Cytometry, Octamer Transcription Factor-3, Early Growth Response Protein 1, Induced Pluripotent Stem Cells, Cellular Reprogramming

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/1051309; http://purl.org/au-research/grants/nhmrc/1092280; Cell Reports, 2017; 21(10):2649-2660; https://hdl.handle.net/2440/133488; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133488
https://doi.org/10.1016/j.celrep.2017.11.029

المؤلفون: Murphy, N.M., Burton, M., Powell, D.R., Rossello, F.J., Cooper, D., Chopra, A., Hsieh, M.J., Sayer, D.C., Gordon, L., Pertile, M.D., Tait, B.D., Irving, H.R., Pouton, C.W.

وصف الملف: pdf

Relation: ispartof: Scientific Reports vol 6; WOS:000380654800001; http://dx.doi.org/10.1038/srep30381; 991005543714207891; https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Haplotyping-the-human-leukocyte-antigen-system/991005543714207891; https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12136166590007891/13136839220007891; alma:61MUN_INST/bibs/991005543714207891

الاتاحة: https://doi.org/10.1038/srep30381
https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Haplotyping-the-human-leukocyte-antigen-system/991005543714207891
https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12136166590007891/13136839220007891

المؤلفون: Zwan, Y.G. (Yvonne ) van der, Rijlaarsdam, M.A. (Martin), Rossello, F.J. (Fernando), Notini, A.J. (Amanda), Boer, S. (Suzan) de, Watkins, D.N. (D. Neil), Gillis, A.J.M. (Ad), Dorssers, L.C.J. (Lambert), White, S.J. (Stefan), Looijenga, L.H.J. (Leendert)

المصدر: PLoS ONE vol. 9 no. 6

وصف الملف: application/pdf

Relation: http://repub.eur.nl/pub/55175; urn:hdl:1765/55175

الاتاحة: http://repub.eur.nl/pub/55175
https://doi.org/10.1371/journal.pone.0098330

المؤلفون: Rossello, F.J., Tothill, R.W., Britt, K., Marini, K.D., Falzon, J., Thomas, D.M., Peacock, C.D., Marchionni, L., Li, J., Bennett, S., Tantoso, E., Brown, T., Chan, P., Martelotto, L.G., Watkins, D.N.

المساهمون: Coleman, W.B.

المصدر: http://dx.doi.org/10.1371/journal.pone.0074432.

مصطلحات موضوعية: Mammalian genomics, Human genomics, Breast cancer, Sequence alignment, Small cell lung cancer, Cancers and neoplasms, Copy number variation, RNA sequencing, Cell Line, Tumor, Animals, Humans, Mice, Nude, Neoplasms, Disease Models, Animal, Oligonucleotide Array Sequence Analysis, Xenograft Model Antitumor Assays, Gene Expression Profiling, Species Specificity, Genome, Human, DNA Copy Number Variations, High-Throughput Nucleotide Sequencing, Exome

وصف الملف: application/pdf

Relation: http://purl.org/au-research/grants/nhmrc/546204; PLoS One, 2013; 8(9):e74432-1-e74432-12; https://hdl.handle.net/2440/134546; Martelotto, L.G. [0000-0002-9625-1183]

الاتاحة: https://hdl.handle.net/2440/134546
https://doi.org/10.1371/journal.pone.0074432

المؤلفون: Cain, J.E, McCaw, A, Jayasekara, W.S.N, Rossello, F.J, Marini, K.D, Irving, A.T, Kansara, M, Thomas, D.M, Ashley, D.M, Watkins, D.N

المساهمون: DUKE-NUS MEDICAL SCHOOL

المصدر: Unpaywall 20201031

مصطلحات موضوعية: panobinostat, adipocyte, animal experiment, animal model, article, cartilage cell, cell differentiation, cell lineage, controlled study, cytostasis, drug exposure, female, gene expression, human, human cell, low drug dose, mouse, nonhuman, osteoblast, osteosarcoma, osteosarcoma cell, priority journal, senescence, tumor xenograft, upregulation

Relation: Cain, J.E, McCaw, A, Jayasekara, W.S.N, Rossello, F.J, Marini, K.D, Irving, A.T, Kansara, M, Thomas, D.M, Ashley, D.M, Watkins, D.N (2013). Sustained low-dose treatment with the Histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells. Sarcoma 2013 : 608964. ScholarBank@NUS Repository. https://doi.org/10.1155/2013/608964; https://scholarbank.nus.edu.sg/handle/10635/180800

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/180800

المؤلفون: Jardé, T., Chan, W.H., Rossello, F.J., Kaur Kahlon, T., Theocharous, M., Kurian Arackal, T., Flores, T., Giraud, M., Richards, E., Chan, E., Kerr, G., Engel, R.M., Prasko, M., Donoghue, J.F., Abe, S.I., Phesse, T.J., Nefzger, C.M., McMurrick, P.J., Powell, D.R., Daly, R.J.

المصدر: http://dx.doi.org/10.1016/j.stem.2020.06.021.

مصطلحات موضوعية: Cell proliferation, Intestines, Paneth Cells, Epithelium, Neuregulin-1

Relation: http://purl.org/au-research/grants/nhmrc/1129600; http://purl.org/au-research/grants/nhmrc/1011187; http://purl.org/au-research/grants/nhmrc/1100531; http://purl.org/au-research/grants/nhmrc/1188689; Cell Stem Cell, 2020; 27(4):646-662.e7; https://hdl.handle.net/2440/133649; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133649
https://doi.org/10.1016/j.stem.2020.06.021

المؤلفون: Liu, X., Ouyang, J.F., Rossello, F.J., Tan, J.P., Davidson, K.C., Valdes, D.S., Schröder, J., Sun, Y.B.Y., Chen, J., Knaupp, A.S., Sun, G., Chy, H.S., Huang, Z., Pflueger, J., Firas, J., Tano, V., Buckberry, S., Paynter, J.M., Larcombe, M.R., Poppe, D.

المصدر: http://dx.doi.org/10.1038/s41586-020-2734-6.

مصطلحات موضوعية: Cellular reprogramming, Chromatin, Fibroblasts, Trophoblasts, Ectoderm, Humans, Transcription, Genetic, Gene Expression Regulation, Adult, Female, Induced Pluripotent Stem Cells

Relation: http://purl.org/au-research/grants/nhmrc/1104560; http://purl.org/au-research/grants/nhmrc/1069830; http://purl.org/au-research/grants/nhmrc/1092280; http://purl.org/au-research/grants/arc/FT180100674; Nature, 2020; 586(7827):101-[107]; https://hdl.handle.net/2440/133651; Martelotto, L.G. [0000-0002-9625-1183]; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133651
https://doi.org/10.1038/s41586-020-2734-6

المؤلفون: Asselin-Labat M.-L., Cain J.E., Papenfuss A.T., Cowley M.J., Watkins D.N., Leong T.L., Gayevskiy V., Steinfort D.P., De Massy M.R., Gonzalez-Rajal A., Marini K.D., Stone E., Chin V., Havryk A., Plit M., Irving L.B., Jennings B.R., McCloy R.A., Jayasekara W.S.N., Alamgeer M., Boolell V., Field A., Russell P.A., Kumar B., Gough D.J., Szczepny A., Ganju V., Rossello F.J.

مصطلحات الفهرس: controlled study, DNA damage, DNA repair, gene dosage, genetic heterogeneity, genotype environment interaction, germline mutation, homologous recombination, human, human cell, lung metastasis, priority journal, smoking, tobacco, tumor microenvironment, whole genome sequencing, article, clinical article, Article

URL: Oncogene
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المؤلفون: Chen, J., Nefzger, C.M., Rossello, F.J., Sun, Y.B.Y., Lim, S.M., Liu, X., de Boer, S., Knaupp, A.S., Li, J., Davidson, K.C., Polo, J.M., Barberi, T.

المصدر: http://dx.doi.org/10.1002/stem.2794.

مصطلحات موضوعية: Pluripotent Stem Cells, Animals, Humans, Mice, Signal Transduction, Cell Differentiation, beta Catenin, Wnt Signaling Pathway

Relation: http://purl.org/au-research/grants/nhmrc/1051117; http://purl.org/au-research/grants/nhmrc/1092280; ARC; Stem Cells, 2018; 36(6):822-833; https://hdl.handle.net/2440/133472; Polo, J.M. [0000-0002-2531-778X]

الاتاحة: https://hdl.handle.net/2440/133472
https://doi.org/10.1002/stem.2794