المؤلفون: Michael Walsh, Claudette Bethune, Andrew Smyth, Jessica Tyrwhitt, Shiangtung W. Jung, Rosie Z. Yu, Yanfeng Wang, Richard S. Geary, Jeffrey Weitz, Sanjay Bhanot

المصدر: Kidney International Reports, Vol 7, Iss 2, Pp 200-209 (2022)

مصطلحات موضوعية: anticoagulation, antisense oligonucleotide, FXI, hemodialysis, pharmacokinetics, randomized controlled trial, Diseases of the genitourinary system. Urology, RC870-923

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2468024921015175; https://doaj.org/toc/2468-0249

URL الوصول: https://doaj.org/article/9d5c672fdff6474baf02354f5b056319

المؤلفون: Stefan Willmann, Eleonora Marostica, Nelleke Snelder, Alexander Solms, Markus Jensen, Maximilian Lobmeyer, Anthonie W. A. Lensing, Claudette Bethune, Erin Morgan, Rosie Z. Yu, Yanfeng Wang, Shiangtung W. Jung, Richard Geary, Sanjay Bhanot

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 890-901 (2021)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2163-8306

URL الوصول: https://doaj.org/article/a0f07a9e368749df85e58f6529f928d9

المؤلفون: Nicholas J. Viney, Shuling Guo, Li‐Jung Tai, Brenda F. Baker, Mariam Aghajan, Shiangtung W. Jung, Rosie Z. Yu, Sheri Booten, Heather Murray, Todd Machemer, Sebastien Burel, Sue Murray, Gustavo Buchele, Sotirios Tsimikas, Eugene Schneider, Richard S. Geary, Merrill D. Benson, Brett P. Monia

المصدر: ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)

مصطلحات موضوعية: Transthyretin, Amyloidosis, Cardiomyopathy, Polyneuropathy, Antisense, Ligand‐conjugated, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2055-5822

URL الوصول: https://doaj.org/article/3297462a8e6e4c1081fbb6040b37c72e

المؤلفون: Colby S. Shemesh, Rosie Z. Yu, Mark S. Warren, Michael Liu, Mirza Jahic, Brandon Nichols, Noah Post, Song Lin, Daniel A. Norris, Eunju Hurh, Jane Huang, Tanya Watanabe, Scott P. Henry, Yanfeng Wang

المصدر: Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 34-47 (2017)

مصطلحات موضوعية: antisense oligonucleotides, pharmacokinetics, drug interaction, metabolism, transport, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253117302408; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/e207d7ae85c046919a7c54818f631e90

المؤلفون: John K. Diep, Rosie Z. Yu, Nicholas J. Viney, Eugene Schneider, Shuling Guo, Scott Henry, Brett Monia, Richard Geary, Yanfeng Wang

المصدر: British Journal of Clinical Pharmacology. 88:5389-5398

مصطلحات موضوعية: Pharmacology, Amyloid Neuropathies, Familial, Oligonucleotides, Humans, Prealbumin, Pharmacology (medical), Oligonucleotides, Antisense

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cf398f01a3cd3a211509b8e0991145
https://doi.org/10.1111/bcp.15468

المؤلفون: Sanjay Bhanot, Eleonora Marostica, Maximilian Lobmeyer, Nelleke Snelder, Erin E. Morgan, Anthonie W. A. Lensing, Richard S. Geary, Markus Jensen, Shiangtung W. Jung, Yanfeng Wang, Rosie Z. Yu, Stefan Willmann, Claudette Bethune, Alexander Solms

المصدر: CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 8, Pp 890-901 (2021)
CPT: Pharmacometrics & Systems Pharmacology

مصطلحات موضوعية: medicine.medical_treatment, Population, RM1-950, Pharmacology, Models, Biological, Article, End stage renal disease, Pharmacokinetics, Renal Dialysis, Humans, Medicine, Pharmacology (medical), education, Factor XI, PK/PD models, Randomized Controlled Trials as Topic, education.field_of_study, Dose-Response Relationship, Drug, business.industry, Research, Articles, Oligonucleotides, Antisense, Pharmacometrics, Modeling and Simulation, Pharmacodynamics, Kidney Failure, Chronic, Asialoglycoprotein receptor, Hemodialysis, Therapeutics. Pharmacology, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c833bb12274e461ae57144f261c44b4
https://doaj.org/article/a0f07a9e368749df85e58f6529f928d9

المؤلفون: Yanfeng Wang, Padma Narayanan, Daniel A. Norris, Richard S. Geary, Scott P. Henry, Tae-Won Kim, Brett P. Monia, Rosie Z. Yu

المصدر: Nucleic Acid Therapeutics. 30:265-275

مصطلحات موضوعية: medicine.medical_specialty, Hematology, biology, business.industry, Immunogenicity, Cmax, Pharmacology, Biochemistry, Titer, Transthyretin, Pharmacokinetics, Internal medicine, Pharmacodynamics, Drug Discovery, Toxicity, Genetics, medicine, biology.protein, Molecular Medicine, business, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9bdd6fde5c778b60361c6e8fcb009283
https://doi.org/10.1089/nat.2020.0867

المؤلفون: Jon W Collins, Scott P. Henry, Richard S. Geary, Brett P. Monia, Elizabeth J. Ackermann, Shannon Hall, Yanfeng Wang, Rosie Z. Yu

المصدر: Nucleic Acid Therapeutics

مصطلحات موضوعية: Male, 0301 basic medicine, Oligonucleotides, Gene Expression, inotersen, Biochemistry, Gastroenterology, Body Mass Index, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, Prealbumin, Drug Dosage Calculations, hereditary TTR amyloidosis, Aged, 80 and over, education.field_of_study, biology, Alanine Transaminase, Middle Aged, Original Papers, Neuroprotective Agents, 030220 oncology & carcinogenesis, Molecular Medicine, Female, RNA Interference, pharmacokinetics, Glomerular Filtration Rate, Adult, oligonucleotide, medicine.medical_specialty, Bilirubin, antisense, Population, Renal function, 03 medical and health sciences, Pharmacokinetics, Internal medicine, pharmacodynamics, Genetics, medicine, Humans, education, Molecular Biology, Serum Albumin, Aged, Amyloid Neuropathies, Familial, Models, Statistical, business.industry, Confidence interval, Transthyretin, 030104 developmental biology, chemistry, Case-Control Studies, Pharmacodynamics, Mutation, Lean body mass, biology.protein, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7738a399c01da5a8eb9f6c5e8d9fd228
https://doi.org/10.1089/nat.2019.0822

المؤلفون: Yanfeng Wang, John K. Diep, Rosie Z. Yu, Eunju Hurh, Ewa Karwatowska‐Prokopczuk, Eugene Schneider, Scott Henry, Sanjay Bhanot, Richard S. Geary

المصدر: Journal of clinical pharmacologyReferences.

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b60c46dc27f55a183d4b9afa6f7b0ecf
https://pubmed.ncbi.nlm.nih.gov/35801818

المؤلفون: Rosie Z Yu, Mark J Graham, Noah Post, Stan Riney, Thomas Zanardi, Shannon Hall, Jennifer Burkey, Colby S Shemesh, Thazha P Prakash, Punit P Seth, Eric E Swayze, Richard S Geary, Yanfeng Wang, Scott Henry

المصدر: Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)

مصطلحات موضوعية: antisense oligonucleotide, disposition, mice, pharmacokinetics, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S2162253117300409; https://doaj.org/toc/2162-2531; https://doaj.org/article/2b26807b841244429f7ffc38c01b9c47

الاتاحة: https://doi.org/10.1038/mtna.2016.26
https://doaj.org/article/2b26807b841244429f7ffc38c01b9c47

المؤلفون: Colby S Shemesh, Rosie Z Yu, Hans J Gaus, Sarah Greenlee, Noah Post, Karsten Schmidt, Michael T Migawa, Punit P Seth, Thomas A Zanardi, Thazha P Prakash, Eric E Swayze, Scott P Henry, Yanfeng Wang

المصدر: Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)

مصطلحات موضوعية: antisense oligonucleotide, biotransformation, metabolism, N-acetyl galactosamine, targeted drug delivery, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S216225311730046X; https://doaj.org/toc/2162-2531; https://doaj.org/article/1de8c3f8738147bdba5db5c61c7a342f

الاتاحة: https://doi.org/10.1038/mtna.2016.31
https://doaj.org/article/1de8c3f8738147bdba5db5c61c7a342f

المؤلفون: Rosie Z Yu, John S Grundy, Scott P Henry, Tae-Won Kim, Daniel A Norris, Jennifer Burkey, Yanfeng Wang, Andrew Vick, Richard S Geary

المصدر: Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)

مصطلحات موضوعية: Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S2162253116300026; https://doaj.org/toc/2162-2531; https://doaj.org/article/246f1041032e42dfa83f03452a855de3

الاتاحة: https://doi.org/10.1038/mtna.2014.69
https://doaj.org/article/246f1041032e42dfa83f03452a855de3

المؤلفون: Yanfeng Wang, Daniel A. Norris, Rosie Z. Yu, Noah Post, Sarah Greenlee

المصدر: Bioanalysis. 11:1909-1912

مصطلحات موضوعية: Bioanalysis, Chemistry, Oligonucleotide, Clinical Biochemistry, General Medicine, Oligonucleotides, Antisense, Pharmacology, Analytical Chemistry, Medical Laboratory Technology, Pharmacokinetics, Liquid chromatography–mass spectrometry, Humans, Tissue Distribution, Tissue distribution, General Pharmacology, Toxicology and Pharmaceutics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183b7e8183addbc9348a7bf9523388fa
https://doi.org/10.4155/bio-2019-0194

المؤلفون: Eunju Hurh, Yanfeng Wang, Rosie Z. Yu, John B. Matson, Noah Post, Hans Gaus, Sarah Greenlee

المصدر: Drug Metabolism and Disposition. 47:1164-1173

مصطلحات موضوعية: Pharmacology, Oligonucleotide, Metabolite, ADME Study, Pharmaceutical Science, Metabolism, 030226 pharmacology & pharmacy, Blood proteins, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, media_common.cataloged_instance, European union, media_common, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c611842ca8914ac5fb1c2d0981792eda
https://doi.org/10.1124/dmd.119.087395

المؤلفون: Yanfeng Wang, Rosie Z. Yu, Scott P. Henry, Richard S. Geary

المصدر: Expert Opinion on Drug Metabolism & Toxicology. 15:475-485

مصطلحات موضوعية: Pharmacology, Clinical pharmacology, business.industry, Oligonucleotide, General Medicine, Prodrug, Toxicology, Ligand (biochemistry), 030226 pharmacology & pharmacy, law.invention, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, law, 030220 oncology & carcinogenesis, Medicine, Distribution (pharmacology), Asialoglycoprotein receptor, business, ADME

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7222b2975d1d028e96a5f949d277b42e
https://doi.org/10.1080/17425255.2019.1621838

المؤلفون: Michael, Walsh, Claudette, Bethune, Andrew, Smyth, Jessica, Tyrwhitt, Shiangtung W, Jung, Rosie Z, Yu, Yanfeng, Wang, Richard S, Geary, Jeffrey, Weitz, Sanjay, Bhanot

المصدر: Kidney international reports. 7(2)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8ae4aa5ef679c132fcc18ff3e3bf48d6
https://pubmed.ncbi.nlm.nih.gov/35155859

المؤلفون: Rosie Z Yu, Tae-Won Kim, An Hong, Tanya A Watanabe, Hans J Gaus, Richard S Geary, Ph.D Rosie Z Yu

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://dmd.aspetjournals.org/content/dmd/early/2006/12/15/dmd.106.012401.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.3165; http://dmd.aspetjournals.org/content/dmd/early/2006/12/15/dmd.106.012401.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1062.3165
http://dmd.aspetjournals.org/content/dmd/early/2006/12/15/dmd.106.012401.full.pdf

المؤلفون: Catarina Nilsson, Rosanne M. Crooke, Nigel Davies, Birgitta Rosengren, Brett P. Monia, Eva Hurt-Camejo, Cristina S. J. Rocha, Tina Rydén-Bergsten, Stan Riney, Daniel Lindén, Rosie Z. Yu, Yanfeng Wang, Peter Gennemark, Anna Tivesten, Dorota Kakol-Palm, Ulf Andersson, Lloyd G. Tillman, Marie Elebring, Björn Carlsson, Mikko Hölttä, Jane Knöchel, Linda Wernevik, Rasmus Jansson-Löfmark, Niclas Clemmensen, Rikard Isaksson, Katrin Walter, Richard S. Geary, Dinko Rekić

المصدر: Science Translational Medicine. 13

مصطلحات موضوعية: 0301 basic medicine, 030204 cardiovascular system & hematology, Pharmacology, 03 medical and health sciences, Subcutaneous injection, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Oral administration, medicine, Animals, Potency, business.industry, Cholesterol, PCSK9, PCSK9 Inhibitors, Serine Endopeptidases, General Medicine, Oligonucleotides, Antisense, medicine.disease, Rats, Bioavailability, Macaca fascicularis, 030104 developmental biology, chemistry, business, Dyslipidemia, Lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197948bccc867454748627a58e0b6234
https://doi.org/10.1126/scitranslmed.abe9117

المؤلفون: Gina McMullen, Charvi Nanavati, Rosie Z. Yu, Yanfeng Wang, Scott P. Henry, Richard S. Geary

المصدر: Nucleic acid therapeutics. 31(4)

مصطلحات موضوعية: Body surface area, Chemistry, Conjugated system, Pharmacology, Oligonucleotides, Antisense, Biochemistry, chemistry.chemical_compound, Interspecies scaling, Single species, Pharmacokinetics, Galactosamine, Drug Discovery, Antisense oligonucleotides, Genetics, Retrospective analysis, Molecular Medicine, Humans, Molecular Biology, Retrospective Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358d598c863e745127456ab0533c214d
https://pubmed.ncbi.nlm.nih.gov/33891483

المؤلفون: Sheri L. Booten, Gustavo Buchele, Mariam Aghajan, Todd Machemer, Brett P. Monia, Richard S. Geary, Nicholas J. Viney, Sue Murray, Merrill D. Benson, Sebastien A. Burel, Sotirios Tsimikas, Shuling Guo, Eugene Schneider, Shiangtung W. Jung, Brenda F. Baker, Heather M. Murray, Li-Jung Tai, Rosie Z. Yu

المصدر: ESC heart failure, vol 8, iss 1
ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)
ESC Heart Failure

مصطلحات موضوعية: lcsh:Diseases of the circulatory (Cardiovascular) system, Oligonucleotides, 030204 cardiovascular system & hematology, Pharmacology, Cardiorespiratory Medicine and Haematology, Amyloid Neuropathies, Ligands, Transthyretin, Mice, 0302 clinical medicine, Familial, Ligand-conjugated, Original Research Articles, Clinical endpoint, Medicine, Prealbumin, Original Research Article, 030212 general & internal medicine, Cancer, biology, Amyloidosis, Liver Disease, Tolerability, 6.1 Pharmaceuticals, Cardiology and Cardiovascular Medicine, Polyneuropathy, Biotechnology, endocrine system, Cardiomyopathy, Clinical Trials and Supportive Activities, 03 medical and health sciences, Rare Diseases, Pharmacokinetics, Clinical Research, Potency, Animals, Antisense, Adverse effect, Amyloid Neuropathies, Familial, business.industry, Ligand‐conjugated, nutritional and metabolic diseases, Evaluation of treatments and therapeutic interventions, Oligonucleotides, Antisense, medicine.disease, Orphan Drug, lcsh:RC666-701, biology.protein, business, Digestive Diseases

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff308bcce12264c19717432639a3fe9f
https://escholarship.org/uc/item/41n576q7